Menu
 
Research menu
Jump to menu

Publications:  Prof Jude Fitzgibbon

Al Seraihi AF, Rio-Machin A, Tawana K et al.(2018). GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML. Leukemia
10.1038/s41375-018-0134-9
https://qmro.qmul.ac.uk/handle/123456789/38923
Araf S, Okosun J, Fitzgibbon J(2018). Predicting early relapse in follicular lymphoma: have we turned a corner?. Lancet Oncol vol. 19, (4) 441-442.
10.1016/S1470-2045(18)30114-1
https://qmro.qmul.ac.uk/handle/123456789/36480
Gascoyne RD, Nadel B, Pasqualucci L et al.(2017). Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015. Hematol Oncol vol. 35, (4) 397-407.
10.1002/hon.2411
Rio-Machin A, Gómez-López G, Muñoz J et al.(2017). The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia. Leukemia vol. 31, (9) 2000-2005.
10.1038/leu.2017.194
https://qmro.qmul.ac.uk/handle/123456789/24558
Tawana K, Wang J, Király PA et al.(2017). Recurrent somatic JAK-STAT pathway variants within a RUNX1-mutated pedigree. Eur J Hum Genet vol. 25, (8) 1020-1024.
10.1038/ejhg.2017.80
https://qmro.qmul.ac.uk/handle/123456789/36112
Tawana K, Rio-Machin A, Preudhomme C et al.(2017). Familial CEBPA-mutated acute myeloid leukemia. SEMINARS IN HEMATOLOGY vol. 54, (2) 87-93.
10.1053/j.seminhematol.2017.04.001
Tawana K, Rio-Machin A, Preudhomme C et al.(2017). Familial CEBPA-mutated acute myeloid leukemia. Semin Hematol vol. 54, (2) 87-93.
10.1053/j.seminhematol.2017.04.001
Korfi K, Ali S, Heward JA et al.(2017). Follicular lymphoma, a B cell malignancy addicted to epigenetic mutations. Epigenetics vol. 12, (5) 370-377.
10.1080/15592294.2017.1282587
https://qmro.qmul.ac.uk/handle/123456789/19089
Mansouri L, Noerenberg D, Young E et al.(2016). Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma. Blood vol. 128, (23) 2666-2670.
10.1182/blood-2016-03-704528
Araf S, Korfi K, Rahim T et al.(2016). Advances in the molecular diagnosis of diffuse large B-cell lymphoma in the era of precision medicine. Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare vol. 16, (10) 1093-1102.
10.1080/14737159.2016.1235974
Araf S, Fitzgibbon J(2016). Pediatric-type FL: simply different. Blood vol. 128, (8) 1030-1031.
10.1182/blood-2016-07-725002
Ripperger T, Tawana K, Kratz C et al.(2016). Clinical utility gene card for: Familial platelet disorder with associated myeloid malignancies. Eur J Hum Genet vol. 24, (8)
10.1038/ejhg.2015.278
Tummala H, Walne AJ, Williams M et al.(2016). DNAJC21 Mutations Link a Cancer-Prone Bone Marrow Failure Syndrome to Corruption in 60S Ribosome Subunit Maturation. Am J Hum Genet vol. 99, (1) 115-124.
10.1016/j.ajhg.2016.05.002
https://qmro.qmul.ac.uk/handle/123456789/15700
Kotsiou E, Okosun J, Besley C et al.(2016). TNFRSF14 aberrations in follicular lymphoma increase clinically significant allogeneic T-cell responses. Blood vol. 128, (1) 72-81.
10.1182/blood-2015-10-679191
https://qmro.qmul.ac.uk/handle/123456789/12275
GROSE RP, Dawkins JBN, Wang J et al.(2016). Reduced expression of histone methyltransferases KMT2C and KMT2D correlates with improved outcome in pancreatic ductal adenocarcinoma. Cancer Research
10.1158/0008-5472.CAN-16-0481
https://qmro.qmul.ac.uk/handle/123456789/12978
Araf S, Wang J, Pangault C et al. (2016). GENOMIC PROFILING REVEALS SPATIAL HETEROGENEITY IN FOLLICULAR LYMPHOMA: IMPLICATIONS FOR PRECISION MEDICINE. HAEMATOLOGICA. vol. 101, 270-270.
Britton D, Casado P, Rajeeve V et al. (2016). PROTEOMIC ANALYSIS OF RELAPSE AML IDENTIFIES OPPORTUNITIES FOR THERAPEUTIC INTERVENTION IN INDIVIDUAL PATIENTS. HAEMATOLOGICA. vol. 101, 373-373.
Okosun J, Wolfson RL, Wang J et al.(2016). Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma (vol 48, pg 183, 2016). NATURE GENETICS vol. 48, (6) 700-700.
10.1038/ng0616-700b
Rio-Machin A, Cardoso S, Tawana K et al. (2016). WHOLE EXOME SEQUENCING REVEALS NOVEL CANDIDATE GENES IN FAMILIAL MDS/AML. HAEMATOLOGICA. vol. 101, 205-206.
Okosun J, Wolfson RL, Wang J et al.(2016). Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nat Genet vol. 48, (6) 700-700.
10.1038/ng0616-700b
DOKAL I(2016). Germline heterozygous DDX41 vriants in a subset of familial myelodysplasia and acute myeloid leukaemia. Leukemia
10.1038/leu.2016.124
https://qmro.qmul.ac.uk/handle/123456789/12225
Okosun J, Montoto S, Fitzgibbon J(2016). The routes for transformation of follicular lymphoma. Current Opinion in Hematology vol. 23, (4) 1-1.
10.1097/MOH.0000000000000255
Tawana K, Fitzgibbon J(2016). Inherited DDX41 mutations: 11 genes and counting. Blood vol. 127, (8) 960-961.
10.1182/blood-2016-01-690909
Okosun J, Wolfson RL, Wang J et al.(2016). Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nature Genetics vol. 48, (2) 183-188.
10.1038/ng.3473
Okosun J, Wolfson RL, Wang J et al. (2016). Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nat Genet. vol. 48, 183-188.
10.1038/ng.3473
Engert A, Balduini C, Brand A et al.(2016). The European Hematology Association Roadmap for European Hematology Research: a consensus document. Haematologica vol. 101, (2) 115-208.
10.3324/haematol.2015.136739
Araf S, Okosun J, Koniali L et al.(2016). Epigenetic dysregulation in follicular lymphoma. Epigenomics vol. 8, (1) 77-84.
10.2217/epi.15.96
Tawana K, Wang J, Renneville A et al.(2015). Disease evolution and outcomes in familial AML with germline CEBPA mutations. Blood vol. 126, (10) 1214-1223.
10.1182/blood-2015-05-647172
Tawana K, Wang J, Kiraly PA et al. (2015). CONVERGENCE OF SOMATIC MUTATIONS WITHIN THE JAK-STAT SIGNALLING PATHWAY IN A NOVEL RUNX1-MUTATED PEDIGREE. HAEMATOLOGICA. vol. 100, 9-10.
Koniali L, Heward J, Loveday C et al. (2015). KDM5 INHIBITION LEADS TO INCREASED H3K4ME3 LEVELS AND CELL DEATH IN GERMINAL CENTRE LYMPHOMA CELL LINES INDEPENDENT OF MLL2 MUTATION STATUS. HAEMATOLOGICA. vol. 100, 104-104.
Noerenberg D, Frick M, Couronne L et al. (2015). NFKBIE MUTATIONS OCCUR IN 15% OF GCB DLBCL AND IN VARIOUS OTHER LYMPHOID MALIGNANCIES. HAEMATOLOGICA. vol. 100, 549-549.
Carlotti E, Wrench D, Rosignoli G et al.(2015). High Throughput Sequencing Analysis of the Immunoglobulin Heavy Chain Gene from Flow-Sorted B Cell Sub-Populations Define the Dynamics of Follicular Lymphoma Clonal Evolution. PLoS One vol. 10, (9)
10.1371/journal.pone.0134833
Kotsiou E, Okosun J, Clear AJ et al. (2014). TNFRSF14 aberrations in Follicular Lymphoma B Cells Result in Increased Alloresponses in Vitro and in Vivo. BLOOD. vol. 124,
Rohatiner AZS, Smith ML, Spinelli O et al.(2014). Myeloblative therapy with autologous haematopoietic stem cell support as consolidation of first remission in acute myeloid leukaemia - very long follow-up. Br J Haematol vol. 167, (5) 724-726.
10.1111/bjh.13055
https://qmro.qmul.ac.uk/handle/123456789/6616
Okosun J, Packham G, Fitzgibbon J(2014). Investigational epigenetically targeted drugs in early phase trials for the treatment of haematological malignancies. Expert Opin Investig Drugs vol. 23, (10) 1321-1332.
10.1517/13543784.2014.923402
Bouska A, McKeithan TW, Deffenbacher KE et al.(2014). Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma. BLOOD vol. 123, (11) 1681-1690.
10.1182/blood-2013-05-500595
Okosun J, Bödör C, Wang J et al.(2014). Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nature Genetics vol. 46, (2) 176-181.
10.1038/ng.2856
Okosun J, Bödör C, Wang J et al.(2014). Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nat Genet vol. 46, (2) 176-181.
10.1038/ng.2856
Haider S, Wang J, Nagano A et al.(2014). A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma. Genome Med vol. 6, (12)
10.1186/s13073-014-0105-3
https://qmro.qmul.ac.uk/handle/123456789/6841
Mutsaers PGNJ, van de Loosdrecht AA, Tawana K et al.(2013). Highly variable clinical manifestations in a large family with a novel GATA2 mutation. Leukemia vol. 27, (11) 2247-2248.
10.1038/leu.2013.105
Bödör C, Grossmann V, Popov N et al.(2013). EZH2 mutations are frequent and represent an early event in follicular lymphoma. Blood vol. 122, (18) 3165-3168.
10.1182/blood-2013-04-496893
Gertner-Dardenne J, Fauriat C, Orlanducci F et al.(2013). The co-receptor BTLA negatively regulates human V gamma 9V delta 2 T-cell proliferation: a potential way of immune escape for lymphoma cells. BLOOD vol. 122, (6) 922-931.
10.1182/blood-2012-11-464685
Green CL, Tawana K, Hills RK et al.(2013). GATA2 mutations in sporadic and familial acute myeloid leukaemia patients with CEBPA mutations. Br J Haematol vol. 161, (5) 701-705.
10.1111/bjh.12317
Okosun J, Clear A, Iqbal S et al. (2013). TNFRSF14 aberrations are associated with death from acute GvHD after reduced-intensity conditioned allogeneic haematopoietic stem cell transplantation for follicular lymphoma. BONE MARROW TRANSPLANTATION. vol. 48, S169-S169.
Robbez-Masson LJ, Bödör C, Jones JL et al.(2013). Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing. PLoS One vol. 8, (11)
10.1371/journal.pone.0078839
https://qmro.qmul.ac.uk/handle/123456789/13790
Bouska A, McKeithan T, Deffenbacher KE et al. (2012). Genetic Abnormalities in Follicular Lymphoma and Transformed Follicular Lymphoma. BLOOD. vol. 120,
Okosun J, Boedoer C, Wang J et al. (2012). Whole Genome Sequencing in Sequential Biopsies Reveals the Genetic Evolution of Follicular Lymphoma to Transformed Follicular Lymphoma. BLOOD. vol. 120,
Delage B, Luong P, Maharaj L et al.(2012). Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis. Cell Death Dis vol. 3,
10.1038/cddis.2012.83
Quintana-Bustamante O, Smith SL-L, Griessinger E et al.(2012). Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis. LEUKEMIA vol. 26, (7) 1537-1546.
10.1038/leu.2012.38
Bödör C, Renneville A, Smith M et al.(2012). Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival. Haematologica vol. 97, (6) 890-894.
10.3324/haematol.2011.054361
Adams D, Altucci L, Antonarakis SE et al.(2012). BLUEPRINT to decode the epigenetic signature written in blood. NATURE BIOTECHNOLOGY vol. 30, (3) 224-226.
10.1038/nbt.2153
Leich E, Zamo A, Horn H et al.(2011). MicroRNA profiles of t(14;18)-negative follicular lymphoma support a late germinal center B-cell phenotype. Blood vol. 118, (20) 5550-5558.
10.1182/blood-2011-06-361972
Okosun J, Fitzgibbon J(2011). It's a targeted world in non-Hodgkin's lymphoma. Br J Nurs vol. 20, (17)
10.12968/bjon.2011.20.Sup10.S28
Fitzgibbon J (2011). A Molecular Portrait of Follicular Lymphoma. EUROPEAN JOURNAL OF CANCER. vol. 47, S33-S33.
10.1016/S0959-8049(11)70349-5
Stevens J, Waters R, Sieniawska C et al.(2011). Serum selenium concentration at diagnosis and outcome in patients with haematological malignancies. Br J Haematol vol. 154, (4) 448-456.
10.1111/j.1365-2141.2011.08744.x
Montoto S, Fitzgibbon J(2011). Transformation of indolent B-cell lymphomas. J Clin Oncol vol. 29, (14) 1827-1834.
10.1200/JCO.2010.32.7577
Szlosarek PW, Luong F, Clear A et al.(2011). Pegylated arginine deiminase (ADI-PEG20) as a potential novel therapy for argininosuccinate synthetase-deficient acute myeloid leukemia. CANCER RESEARCH vol. 71,
Bödör C, O'Riain C, Wrench D et al.(2011). EZH2 Y641 mutations in follicular lymphoma. Leukemia vol. 25, (4) 726-729.
10.1038/leu.2010.311
Wrench D, Leighton P, Skibola CF et al.(2011). SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma. Blood vol. 117, (11) 3147-3150.
10.1182/blood-2010-10-315382
Langabeer SE, Owen CJ, McCarron SL et al.(2010). A novel RUNX1 mutation in a kindred with familial platelet disorder with propensity to acute myeloid leukaemia: male predominance of affected individuals. Eur J Haematol vol. 85, (6) 552-553.
10.1111/j.1600-0609.2010.01513.x
Wrench D, Sangaralingam A, Tayyib H et al. (2010). TNFRSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenvironment In Transformed Follicular Lymphoma. BLOOD. vol. 116, 349-349.
Wrench D, Montoto S, Fitzgibbon J(2010). Molecular signatures in the diagnosis and management of follicular lymphoma. Curr Opin Hematol vol. 17, (4) 333-340.
10.1097/MOH.0b013e328338ccab
Ghazaly E, Smith P, Quentmeier H et al. (2010). ACCUMULATION OF 2-HYDROXYGLUTARATE (2-HG) IN NORMAL KARYOTYPE AML PATIENTS WITH IDH1 MUTATION. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 95, 20-20.
O' Riain C, Smith P, Clear A et al. (2010). EZH2 MUTATION IN FOLLICULAR LYMPHOMA. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 95, 167-167.
Wrench J, Skibola C, Matthews J et al. (2010). SNP RS6457327 ON CHROMOSOME 6P PREDICTS TRANSFORMATION OF FOLLICULAR LYMPHOMA. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 95, 170-171.
Sziosarek PW, Delage B, O'Riain C et al.(2010). Effect of inactivation of argininosuccinate synthetase on sensitivity of lymphomas to caspase-dependent apoptosis following treatment with arginine deiminase. JOURNAL OF CLINICAL ONCOLOGY vol. 28, (15)
Langabeer SE, Owen CJ, McCarron SL et al. (2010). A novel RUNX1 mutation in an Irish kindred with familial platelet disorder with propensity to acute myeloid leukaemia. BRITISH JOURNAL OF HAEMATOLOGY. vol. 149, 73-73.
Owen C, Fitzgibbon J, Paschka P(2010). The clinical relevance of Wilms Tumour 1 (WT1) gene mutations in acute leukaemia. HEMATOL ONCOL vol. 28, (1) 13-19.
10.1002/hon.931
O'Riain C, Calaminici M, Clear A et al. (2010). DNA Methylation and Polycomb Repression in Follicular Lymphoma. MODERN PATHOLOGY. vol. 23, 315A-315A.
O'Riain C, O'Shea DM, Yang Y et al.(2009). Array-based DNA methylation profiling in follicular lymphoma. Leukemia vol. 23, (10) 1858-1866.
10.1038/leu.2009.114
Fitzgibbon J (2009). The Molecular Pathogenesis of Follicular Lymphoma. JOURNAL OF MEDICAL GENETICS. vol. 46, S24-S24.
Leich E, Salaverria I, Bea S et al.(2009). Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations. BLOOD vol. 114, (4) 826-834.
10.1182/blood-2009-01-198580
Oke A, Pearce D, Wilkinson RW et al.(2009). AZD1152 Rapidly and Negatively Affects the Growth and Survival of Human Acute Myeloid Leukemia Cells In vitro and In vivo. CANCER RES vol. 69, (10) 4150-4158.
10.1158/0008-5472.CAN-08-3203
Carlotti E, Wrench D, Matthews J et al.(2009). Transformation of follicular lymphoma to diffuse large B-cell lymphoma may occur by divergent evolution from a common progenitor cell or by direct evolution from the follicular lymphoma clone. Blood vol. 113, (15) 3553-3557.
10.1182/blood-2008-08-174839
O'Shea D, O'Riain C, Gupta M et al.(2009). Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation. Blood vol. 113, (10) 2298-2301.
10.1182/blood-2008-08-174953
Fitzgibbon J, Gale R, Hills R et al.(2009). Comparing Apples and Oranges in Normal Karyotype Acute Myeloid Leukemia REPLY. J CLIN ONCOL vol. 27, (3) 474-476.
10.1200/JCO.2008.19.4894
Wrench D, Waters R, Carlotti E et al.(2009). Clinical relevance of MDM2 SNP 309 and TP53 Arg72Pro in follicular lymphoma. HAEMATOL-HEMATOL J vol. 94, (1) 148-150.
10.3324/haematol.13533
Owen CJ, Toze CL, Koochin A et al.(2008). Five new pedigrees with inherited RUNX1 mutations causing familial platelet disorder with propensity to myeloid malignancy. Blood vol. 112, (12) 4639-4645.
10.1182/blood-2008-05-156745
Virappane P, Gale R, Hills R et al. (2008). Mutation of the Wilms' Tumor 1 Gene Is a Poor Prognostic Factor Associated With Chemotherapy Resistance in Normal Karyotype Acute Myeloid Leukemia: The United Kingdom Medical Research Council Adult Leukaemia Working Party. JOURNAL OF CLINICAL ONCOLOGY. vol. 26, 5429-5435.
10.1200/JCO.2008.16.0333
Deffenbacher KE, Wright G, Iqbal J et al. (2008). Genetic Abnormalities Involved in the Development and Progression of Follicular Lymphoma. BLOOD. vol. 112, 714-714.
Yang YW, Wrench DJ, Lister TA et al. (2008). Recurrent Chromosomal Intermingling Interactions at the BCL2 Locus in T(14;18) +Ve and -Ve Cell Lines. BLOOD. vol. 112, 713-713.
Quintana-Bustamante O, Smith SLL, Fitzgibbon J et al. (2008). Role of Different C/EBP alpha Mutations in AML Transformation. BLOOD. vol. 112, 484-484.
O'Shea D, O'Riain C, Taylor C et al.(2008). The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival. Blood vol. 112, (8) 3126-3129.
10.1182/blood-2008-05-154013
Raghavan M, Smith L-L, Lillington DM et al.(2008). Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia. Blood vol. 112, (3) 814-821.
10.1182/blood-2008-01-132431
Wrench D, Waters R, Matthews J et al. (2008). MDM2 309 and TP53 ARG72PRO SNP genotypes do not predict clinical outcome of follicular lymphoma. ANNALS OF ONCOLOGY. vol. 19, 178-178.
Stevens JM, Juliger S, Summers K et al. (2008). METHYLSELENINIC ACID DEMONSTRATES ANTI-LEUKAEMIC ACTIVITY AND SENSITISES AML CELLS TO THE EFFECTS OF CYTOTOXIC AGENTS BY INITIATING THE UNFOLDED PROTEIN RESPONSE. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 93, 115-116.
O'Riain C, O'Shea D, Yang Y et al. (2008). Methylation profiling in 158 cases of previously untreated follicular lymphoma (FL). ANNALS OF ONCOLOGY. vol. 19, 101-101.
O'Shea D, O'Riain C, MacDougall F et al. (2008). SNP array genotyping in 182 diagnostic follicular lymphoma cases identifies sites of AUPD associated with overall survival and risk of transformation. ANNALS OF ONCOLOGY. vol. 19, 111-111.
Owen C, Virappane P, Alikian M et al.(2008). WTX is rarely mutated in acute myeloid leukemia. HAEMATOL-HEMATOL J vol. 93, (6) 947-948.
10.3324/haematol.12509
Owen CJ, Toze CJ, Forrest DL et al.(2008). Should patients with myelodysplasia and/or acute myeloid leukemia (MDS/AML) be screened for inherited runx1 mutations prior to sibling donor allografting?. ANN HEMATOL vol. 87, S11-S11.
Owen C, Barnett M, Fitzgibbon J(2008). Familial myelodysplasia and acute myeloid leukaemia--a review. Br J Haematol vol. 140, (2) 123-132.
10.1111/j.1365-2141.2007.06909.x
Carlotti E, Wrench D, Iqbal S et al. (2007). Determining the mechanism of transformation of follicular lymphoma into diffuse large B cell lymphoma. BLOOD. vol. 110, 61A-61A.
Virappane P, Gale RE, Hills R et al. (2007). Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemoresistance in normal karyotype acute myeloid leukemia. BLOOD. vol. 110, 113A-113A.
Owen CJ, Yin JAL, Toze CJ et al. (2007). Should patients with myelodysplasia and/or acute myeloid leukemia (MDS/AML) be screened for inherited RUNX1 mutations prior to sibling donor allografting?. BLOOD. vol. 110, 336B-336B.
Jüliger S, Goenaga-Infante H, Lister TA et al.(2007). Chemosensitization of B-cell lymphomas by methylseleninic acid involves nuclear factor-kappaB inhibition and the rapid generation of other selenium species. Cancer Res vol. 67, (22) 10984-10992.
10.1158/0008-5472.CAN-07-0519
Fitzgibbon J, Iqbal S, Davies A et al.(2007). Genome-wide detection of recurring sites of uniparental disomy in follicular and transformed follicular lymphoma. Leukemia vol. 21, (7) 1514-1520.
10.1038/sj.leu.2404696
Owen C, Stevens J, Amess J et al. (2007). Familial myelodysplasia with monosomy 7. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 92, 234-234.
O'Shea D, Iqbal S, Carlotti E et al. (2007). SNP array profiling of follicular lymphoma reveals novel regions of acquired UPD. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 92, 62-62.
Kakkas I, Summers K, Fleischmann C et al. (2007). Simultaneous detection of FLT3, NPM1 and WT1 mutations using high-resolution capillary electrophoresis. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 92, 370-370.
Virappane P, Gale RE, Hills RK et al. (2007). Wilms' tumour 1 mutation in normal karyotype aml. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 92, 19-20.
Raghavan M, Smith LL, Chaplin T et al. (2007). Frequent relapse of acute myeloid leukaemia by mitotic recombination. BRITISH JOURNAL OF HAEMATOLOGY. vol. 137, 25-25.
Juliger S, Joel SP, Fitzgibbon J et al. (2007). Serum selenium at presentation may predict disease outcome in acute myeloid leukaemia (AML). BRITISH JOURNAL OF HAEMATOLOGY. vol. 137, 65-65.
Summers K, Stevens J, Kakkas I et al.(2007). Wilms' tumour 1 mutations are associated with FLT3-ITD and failure of standard induction chemotherapy in patients with normal karyotype AML. Leukemia vol. 21, (3) 550-551.
10.1038/sj.leu.2404514
Davies AJ, Rosenwald A, Wright G et al.(2007). Transformation of follicular lymphoma to diffuse large B-cell lymphoma proceeds by distinct oncogenic mechanisms. BRIT J HAEMATOL vol. 136, (2) 286-293.
10.1111/j.1365-2141.2006.06439.x
O'Shea D, Iqbal S, Carlotti E et al. (2006). aUPD in the clonal evolution of follicular lymphoma. BLOOD. vol. 108, 585A-585A.
Last K, Maharaj L, Perry J et al.(2006). The activity of methylated and non-methylated selenium species in lymphoma cell lines and primary tumours. ANN ONCOL vol. 17, (5) 773-779.
10.1093/annonc/mdl004
Zhang LY, Smith ML, Schultheis B et al.(2006). A novel K5091 mutation of KIT identified in familial mastocytosis - in vitro and in vivo responsiveness to imatinib therapy. LEUKEMIA RES vol. 30, (4) 373-378.
10.1016/j.leukres.2005.08.015
Smith LL, Pearce D, Smith ML et al.(2006). Development of a quantitative real-time polymerase chain reaction method for monitoring CEBPA mutations in normal karyotype acute myeloid leukaemia. BRIT J HAEMATOL vol. 133, (1) 103-105.
10.1111/j.1365-2141.2006.06001.x
Juliger S, Goenaga-Infante H, Fitzgibbon J et al. (2005). Methylseleninic acid results in rapid changes in intracellular selenium species and sensitises human lymphoma cells to doxorubicin. BLOOD. vol. 106, 503A-503A.
Joel SP, Oke A, Foot N et al. (2005). The activity of the novel aurora kinase B inhibitor AZD1152 in acute myeloid leukaemia cells. BLOOD. vol. 106, 943A-943A.
Fitzgibbon J, Smith L-L, Raghavan M et al.(2005). Association between acquired uniparental disomy and homozygous gene mutation in acute myeloid leukemias. Cancer Res vol. 65, (20) 9152-9154.
10.1158/0008-5472.CAN-05-2017
Davies AJ, Lee AM, Taylor C et al.(2005). A limited role for TP53 mutation in the transformation of follicular lymphoma to diffuse large B-cell lymphoma. LEUKEMIA vol. 19, (8) 1459-1465.
10.1038/sj.leu.2403802
Smith LL, Smith M, Goff L et al. (2005). Development of a quantitative real-time PCR method for monitoring CEBPA mutations in normal karyotype acute myeloid leukaemia patient samples. EXPERIMENTAL HEMATOLOGY. vol. 33, 73-73.
Davies A, Iqbal S, Fitzgibbon J et al. (2005). Homozygosity mapping by genome-wide SNP analysis of the transformation of follicular lymphoma (FL) to diffuse large B-cell lymphoma (TxDLBCL). ANNALS OF ONCOLOGY. vol. 16, 106-106.
Davies A, Arch R, Goff L et al. (2005). Refinement of the 13q31-32 amplicon in B-cell non-Hodgkin's lymphoma by a simultaneous genomic and transcriptional approach. ANNALS OF ONCOLOGY. vol. 16, 80-80.
Suraweera N, Meijne E, Moody J et al.(2005). Mutations of the PU.1 Ets domain are specifically associated with murine radiation-induced, but not human therapy-related, acute myeloid leukaemia. Oncogene vol. 24, (22) 3678-3683.
10.1038/sj.onc.1208422
Lee A, Davies AJ, Clear A et al. (2005). Tissue microarray is a useful tool in the evaluation of genes implicated in transformation of follicular lymphoma. JOURNAL OF PATHOLOGY. vol. 205, 11-11.
Smith ML, Arch R, Smith L-L et al.(2005). Development of a human acute myeloid leukaemia screening panel and consequent identification of novel gene mutation in FLT3 and CCND3. Br J Haematol vol. 128, (3) 318-323.
10.1111/j.1365-2141.2004.05324.x
Smith ML, Cavenagh JD, Lister TA et al.(2004). Brief report - Mutation of CEBPA in familial acute myeloid leukemia. NEW ENGL J MED vol. 351, (23) 2403-2407.
10.1056/NEJMoa041331
Smith ML, Cavenagh JD, Lister TA et al.(2004). Mutation of CEBPA in familial acute myeloid leukemia. N Engl J Med vol. 351, (23) 2403-2407.
10.1056/NEJMoa041331
Fitzgibbon J, Smith M, Arch R et al. (2004). Development of a human acute myeloid leukaemia screening panel and identification of novel gene mutations. BLOOD. vol. 104, 817A-817A.
Ridler C, Smith M, Milne T et al. (2004). Flow cytometric FLT3 expression in acute leukaemias is of diagnostic value but does not correlate with ITD/D835Y mutation status. BLOOD. vol. 104, 823A-823A.
Fitzgibbon J, Smith M, Cavenagh J et al. (2004). Mutation of CEBPA in familial acute myeloid leukaemia. BLOOD. vol. 104, 555A-555A.
Davies AJ, Lee AM, Taylor C et al. (2004). Sequential time-point mutational analysis of TP53 in follicular lymphoma undergoing transformation to large B-cell lymphoma. BLOOD. vol. 104, 382A-382A.
Last K, Perry J, Maharaj L et al. (2004). The induction of apoptosis in lymphoma cells by methylseleninic acid and selenodiglutathione. BLOOD. vol. 104, 686A-686A.
Lee A, Davies A, Clear A et al. (2004). Tissue microarray is a useful tool in the evaluation of genes implicated in transformation of follicular lymphoma. BLOOD. vol. 104, 624A-624A.
Last KW, Rohatiner AZS, Fitzgibbon J et al.(2004). Serum selenium in lymphoma - In reply. J CLIN ONCOL vol. 22, (16) 3430-3430.
10.1200/JCO.2004.99.131
Nilsen H, An Q, Fitzgibbon J et al. (2004). Complex phenotypes associated with uracil in DNA in mammals. BRITISH JOURNAL OF CANCER. vol. 91, S71-S71.
Iqbal S, Jenner MJR, Summers KE et al.(2004). Reliable detection of clonal IgH/Bcl2 MBR rearrangement in follicular lymphoma: methodology and clinical significance. Br J Haematol vol. 124, (3) 325-328.
10.1046/j.1365-2141.2003.04796.x
Goff LK, Iqbal S, Jenner MJ et al. (2003). Reliable detection of clonal IgH/Bcl-2 MBR rearrangement in follicular lymphoma: Methodology and clinical significance. BLOOD. vol. 102, 633A-633A.
Debernardi S, Van Delft F, Davies A et al. (2003). The Wiskott-Aldrich-Syndrome family member 1 (WASF1) gene on 6q21 is down-regulated in specific AML cytogenetic subtypes. BLOOD. vol. 102, 582A-582A.
Last KW, Cornelius V, Delves T et al.(2003). Presentation serum selenium predicts for overall survival, dose delivery, and first treatment response in aggressive non-Hodgkin's lymphoma. J Clin Oncol vol. 21, (12) 2335-2341.
10.1200/JCO.2003.06.145
Snaddon J, Smith ML, Neat M et al.(2003). Mutations of CEBPA in acute myeloid leukemia FAB types M1 and M2. Genes Chromosomes Cancer vol. 37, (1) 72-78.
10.1002/gcc.10185
Smith ML, Snaddon J, Neat M et al.(2003). Mutation of BRAF is uncommon in AML FAB type M1 and M2. LEUKEMIA vol. 17, (1) 274-275.
10.1038/sj.leu.2402787
Davies A, Rosenwald A, Wright G et al. (2002). Gene expression profiling in paired follicular lymphoma samples pre- and post-transformation to large B cell lymphoma. BLOOD. vol. 100, 315A-316A.
Jenner M, Summers K, Matthews J et al. (2002). Genetic risk factor for follicular lymphoma within the MHC region. BLOOD. vol. 100, 567A-567A.
Fitzgibbon J, Arch R, Davies A et al. (2002). Refinement and evaluation of candidate genes within the 13q amplicon in germinal centre lymphoma. BLOOD. vol. 100, 189B-190B.
Jenner MJ, Summers KE, Norton AJ et al.(2002). JH probe real-time quantitative polymerase chain reaction assay for Bcl-2/IgH rearrangements. Br J Haematol vol. 118, (2) 550-558.
10.1046/j.1365-2141.2002.03623.x
Summers KE, Davies AJ, Matthews J et al.(2002). The relative role of peripheral blood and bone marrow for monitoring molecular evidence of disease in follicular lymphoma by quantitative real-time polymerase chain reaction. Br J Haematol vol. 118, (2) 563-566.
10.1046/j.1365-2141.2002.03641.x
Snaddon J, Neat M, Fitzgibbon J et al.(2002). Mutations in the runt homology domain of CBFalpha2 in myeloid malignancies with acquired trisomy 21. Cancer Genet Cytogenet vol. 136, (2) 151-152.
10.1016/S0165-4608(02)00525-3
Summers KE, Goff LK, Wilson AG et al.(2001). The frequency of the Bcl-2/IgH t(14;18)(q32;q21) rearrangement in normal individuals implications for the monitoring of disease in patients with follicular lymphoma. LEUKEMIA vol. 15, (12) 2024-2024.
Jenner MJ, Summers KE, Norton AJ et al.(2001). A universal strategy for quantifying Bcl-2/IgH breakpoints in follicular lymphoma. BLOOD vol. 98, (11) 126A-126A.
Snaddon J, Arch R, Sutcliffe K et al.(2001). Identification of several novel polymorphisms in the low affinity FC inhibitory receptor FCGR2B. BLOOD vol. 98, (11) 164B-164B.
Snaddon J, Neat M, Smith ML et al.(2001). Mutations in the runt domain of CBFA2 in myeloid malignancies with acquired trisomy 21. BLOOD vol. 98, (11) 195B-195B.
Snaddon J, Smith ML, Neat M et al.(2001). Mutations of CEBPA in acute myeloid leukaemia FAB-type M1 and M2. BLOOD vol. 98, (11) 195B-195B.
Davies AJ, Summers KE, Matthews J et al.(2001). The relative role of peripheral blood and bone marrow for monitoring molecular evidence of disease in follicular lymphoma by quantitative real time PCR. BLOOD vol. 98, (11) 124A-125A.
Neat MJ, Foot N, Jenner M et al.(2001). Localisation of a novel region of recurrent amplification in, follicular lymphoma to an similar to 6.8 Mb region of 13q32-33. GENE CHROMOSOME CANC vol. 32, (3) 236-243.
10.1002/gcc.1187
Foot N, Neat M, Jenner M et al.(2001). Localisation of a novel region of amplification in follicular lymphoma tumours to a 24cR region of human chromosome 13. J MED GENET vol. 38, S44-S44.
Last KW, Cornelius V, Delves T et al.(2001). Presentation serum selenium predicts for overall survival in patients with diffuse large B-cell (DLBC) lymphoma. BRIT J CANCER vol. 85, 59-59.
Summers KE, Goff LK, Wilson AG et al.(2001). Frequency of the Bcl-2/IgH rearrangement in normal individuals: implications for the monitoring of disease in patients with follicular lymphoma. J Clin Oncol vol. 19, (2) 420-424.
10.1200/JCO.2001.19.2.420
Jenner MJ, Matthews J, Summers K et al.(2000). Application of real time PCR to establishing clonality of Bcl-2 rearrangements in patients with follicular lymphoma. BLOOD vol. 96, (11) 332A-332A.
Fitzgibbon J, Hill AS, Arch RS et al.(2000). Identification of a novel polymorphism in the human FCGR2B gene: Correlation with response to Rituximab treatment in patients with follicular lymphoma. BLOOD vol. 96, (11) 179B-179B.
Neat M, Foot N, Jenner M et al.(2000). Localisation of a novel region of amplification in follicular lymphoma to an similar to 6.8 Mb region of human chromosome 13q32-33. BLOOD vol. 96, (11) 87A-87A.
Last KW, Cornelius VR, Delves T et al.(2000). Presentation serum selenium predicts for overall survival in patients with diffuse large B-cell (DLBC) lymphoma. BLOOD vol. 96, (11) 335A-335A.
Return to top