Menu
 
Research menu
Jump to menu

Publications:  Dr Andrew Stagg

Giles EM, Stagg AJ (2017) . Type 1 Interferon in the Human Intestine-A Co-ordinator of the Immune Response to the Microbiota.Inflamm Bowel Dis vol. 23, (4) 524-533.
10.1097/MIB.0000000000001078
Gordon H, Hoti I, Lindsay JO et al. (2017) . Circulating non-classical monocytes are reduced in patients with active IBD but increase after vedolizumab: a role for alpha 4 beta 7 in myeloid cell recruitment to the inflamed intestine. JOURNAL OF CROHNS & COLITIS. vol. 11, S104-S105.
McCarthy N, Gordon H, Rahman S et al. (2017) . Mucosal inflammation promotes activation of circulating Vd2+T-cells in Crohn's disease. JOURNAL OF CROHNS & COLITIS. vol. 11, S107-S107.
McCarthy N, Gordon H, Rahman S et al. (2017) . P059 Mucosal inflammation promotes activation of circulating Vδ2+ T-cells in Crohn's disease.J Crohns Colitis vol. 11, (suppl_1)
10.1093/ecco-jcc/jjx002.185
Hedin CR, van der Gast CJ, Stagg AJ et al. (2017) . The gut microbiota of siblings offers insights into microbial pathogenesis of inflammatory bowel disease.Gut Microbes1-7.
10.1080/19490976.2017.1284733
http://qmro.qmul.ac.uk/xmlui/handle/123456789/19559
Hedin C, van der Gast CJ, Rogers GB et al. (2016) . Siblings of patients with Crohn's disease exhibit a biologically relevant dysbiosis in mucosal microbial metacommunities.Gut vol. 65, (6) 944-953.
10.1136/gutjnl-2014-308896
Tyler C, McCarthy N, Moser B et al. (2016) . Human intestinal V delta 2+T-cells acquire antigen-presenting potency upon exposure to microbial phosphoantigen: modulation by mucosal inflammation and vedolizumab therapy.JOURNAL OF CROHNS & COLITIS vol. 10, S29-S29.
Whitehouse A, Mushtaq N, McCarthy N et al. (2016) . Increased Airway Dendritic Cell Activation And Altered Subset Distribution In London Children Exposed To Higher Levels Of Pollution. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 193,
Anderson JL, Hedin CR, Benjamin JL et al. (2015) . Dietary intake of inulin-type fructans in active and inactive Crohn's disease and healthy controls: a case-control study.J Crohns Colitis vol. 9, (11) 1024-1031.
10.1093/ecco-jcc/jjv136
McCarthy NE, Hedin CR, Sanders TJ et al. (2015) . Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease.Journal of Clinical Investigation vol. 125, (8) 3215-3225.
10.1172/JCI80840
http://qmro.qmul.ac.uk/xmlui/handle/123456789/14670
Lahiri R, Derwa Y, Bashir Z et al. (2015) . EARLY MONOCYTE DYSFUNCTION IN PATIENTS WHO DEVELOP SYSTEMIC INFLAMMATORY RESPONSE SYNDROME (SIRS) AND SEPSIS AFTER HEPATOPANCREATICOBILIARY SURGERY. JOURNAL OF HEPATOLOGY. vol. 62, S290-S291.
Beamish E, Pattisson C, Johnson J et al. (2015) . Improving the Outcome of Stoma Reversal Surgery: Impact of Microflora. FASEB JOURNAL. vol. 29,
Brugha R, Mushtaq N, McCarthy NE et al. (2015) . Respiratory tract dendritic cells in paediatric asthma.Clin Exp Allergy vol. 45, (3) 624-631.
10.1111/cea.12457
http://qmro.qmul.ac.uk/xmlui/handle/123456789/6638
Lahiri R, Derwa Y, Bashir Z et al. (2015) . Systemic Inflammatory Response Syndrome After Major Abdominal Surgery Predicted by Early Upregulation of TLR4 and TLR5.Ann Surg vol. 2015, (3)
10.5966/sctm.2012-0137
http://qmro.qmul.ac.uk/xmlui/handle/123456789/9508
McCarthy NE, Hedin CR, Sanders TJ et al. (2014) . Colonic V delta 2+T-cells display elevated TNF production and reversible ablation by azathioprine therapy in Crohn's disease. IMMUNOLOGY. vol. 143, 165-165.
Wildemann M, Mushtaq N, McCarthy N et al. (2014) . Fossil fuel derived ambient particulate matter (PM10) induces multiple pathways of activation in human dendritic cells.IMMUNOLOGY vol. 143, 99-99.
http://qmro.qmul.ac.uk/xmlui/handle/123456789/6739
Mann ER, Bernardo D, Ng SC et al. (2014) . Human gut dendritic cells drive aberrant gut-specific t-cell responses in ulcerative colitis, characterized by increased IL-4 production and loss of IL-22 and IFNγ.Inflamm Bowel Dis vol. 20, (12) 2299-2307.
10.1097/MIB.0000000000000223
Vossenkämper A, Hundsrucker C, Page K et al. (2014) . A CD3-specific antibody reduces cytokine production and alters phosphoprotein profiles in intestinal tissues from patients with inflammatory bowel disease.Gastroenterology vol. 147, (1) 172-183.
10.1053/j.gastro.2014.03.049
http://qmro.qmul.ac.uk/xmlui/handle/123456789/5879
Hedin C, van der Gast C, Rogers G et al. (2014) . OC-051 Siblings Of Crohn's Disease Patients Exhibit A Biologically Relevant Dysbiosis In The Mucosal Microbial Community: A 16s Rrna Gene Pyrosequencing Study.Gut vol. 63 Suppl 1,
10.1136/gutjnl-2014-307263.51
Al-Hassi HO, Mann ER, Sanchez B et al. (2014) . Altered human gut dendritic cell properties in ulcerative colitis are reversed by Lactobacillus plantarum extracellular encrypted peptide STp.Mol Nutr Food Res vol. 58, (5) 1132-1143.
10.1002/mnfr.201300596
Sanders TJ, McCarthy NE, Giles EM et al. (2014) . Increased production of retinoic acid by intestinal macrophages contributes to their inflammatory phenotype in patients with Crohn's disease.Gastroenterology vol. 146, (5)
10.1053/j.gastro.2014.01.057
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15329
Hedin C, van der Gast C, Rogers G et al. (2014) . 16S rRNA gene pyrosequencing indicate that siblings of Crohn's disease patients exhibit a biologically relevant dysbiosis in the mucosal microbiota communities.JOURNAL OF CROHNS & COLITIS vol. 8, S11-S12.
10.1016/S1873-9946(14)60021-0
Hedin CR, McCarthy NE, Louis P et al. (2014) . Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings.Gut
10.1136/gutjnl-2013-306226
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15330
Brugha RE, Mushtaq N, Stagg A et al. (2014) . First Description Of Dendritic Cell Subsets In Induced Sputum From Children With Asthma. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 189,
Wildemann M, Mushtaq N, Sanders TJ et al. (2014) . Fossil Fuel And Biomass Derived Particulate Matter (pm) Induce Distinct Profiles Of Activation And Aryl Hydrocarbon Receptor (ahr) Signalling In Human Dendritic Cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 189,
Vossenkamper A, Blair P, Safinia N et al. (2013) . A role for gut-associated lymphoid tissue in shaping the human B cell repertoire. IMMUNOLOGY. vol. 140, 27-27.
Giles E, Pathak M, Sanders TJ et al. (2013) . Constitutive Type I Interferon, via STAT1 activation, promotes regulatory T cell function in the healthy human intestine, but not in inflammatory bowel disease. IMMUNOLOGY. vol. 140, 168-168.
Wildemann M, Mushtaq N, Sanders TJ et al. (2013) . Fossil fuel derived particulate matter (PM10) induces maturation and aryl hydrocarbon receptor (AhR) signalling in human dendritic cells. IMMUNOLOGY. vol. 140, 33-33.
Sanders TJ, McCarthy NE, Giles EM et al. (2013) . Retinoic acid generation by human intestinal CD14(+) macrophages is enhanced in Crohn's disease and maintains an inflammatory phenotype. IMMUNOLOGY. vol. 140, 32-32.
McCarthy NE, Bashir Z, Vossenkämper A et al. (2013) . Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells.J Immunol vol. 191, (5) 2752-2763.
10.4049/jimmunol.1202959
http://qmro.qmul.ac.uk/xmlui/handle/123456789/5470
Vossenkämper A, Blair PA, Safinia N et al. (2013) . A role for gut-associated lymphoid tissue in shaping the human B cell repertoire.J Exp Med vol. 210, (9) 1665-1674.
10.1084/jem.20122465
http://qmro.qmul.ac.uk/xmlui/handle/123456789/5436
Al-Hassi HO, Bernardo D, Murugananthan AU et al. (2013) . A mechanistic role for leptin in human dendritic cell migration: differences between ileum and colon in health and Crohn's disease.Mucosal Immunol vol. 6, (4) 751-761.
10.1038/mi.2012.113
Alazawi W, Lahiri R, Spyrou A et al. (2013) . PATIENTS WITH COMPENSATED CIRRHOSIS HAVE SELECTIVE PARESIS OF FLAGELLIN-INDUCED INNATE IMMUNE RESPONSES DUE TO FAILURES IN ERK SIGNALLING. JOURNAL OF HEPATOLOGY. vol. 58, S133-S134.
Groves KC, Bibby DF, Clark DA et al. (2012) . Disease Progression in HIV-1-Infected Viremic Controllers.J Acquir Immune Defic Syndr vol. 61, (4) 407-416.
10.1097/QAI.0b013e318269c414
Mann ER, McCarthy NE, Peake STC et al. (2012) . Skin- and gut-homing molecules on human circulating γδ T cells and their dysregulation in inflammatory bowel disease.Clin Exp Immunol vol. 170, (2) 122-130.
10.1111/j.1365-2249.2012.04649.x
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15333
Sanders TJ, McCarthy NE, Giles EM et al. (2012) . Retinoic acid production in the human intestine: antigen presenting cell retinaldehyde dehydrogenase activity is enhanced in inflammatory bowel disease. IMMUNOLOGY. vol. 137, 78-78.
McCarthy NE, Hedin CR, Vossenkaemper A et al. (2012) . HUMAN ANTI-MICROBIAL V delta 2+T-CELLS ARE NOVEL INTESTINAL LYMPHOCYTES WITH FUNCTIONAL RELEVANCE IN CROHN'S DISEASE. GUT. vol. 61, A4-A4.
10.1136/gutjnl-2012-302514a.9
Mann ER, Bernardo D, Al-Hassi HO et al. (2012) . Human gut-specific homeostatic dendritic cells are generated from blood precursors by the gut microenvironment.Inflamm Bowel Dis vol. 18, (7) 1275-1286.
10.1002/ibd.21893
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15337
Sanders TJ, McCarthy NE, Giles E et al. (2012) . INTESTINAL INFLAMMATION REGULATES RETINOIC ACID DEPENDENT IMPRINTING OF GUT TROPISM BY DENDRITIC CELLS INDEPENDENTLY OF RALDH EXPRESSION. GUT. vol. 61, A402-A402.
10.1136/gutjnl-2012-302514d.256
Hedin CR, Taylor K, Louis P et al. (2012) . MICROBIAL, PHENOTYPIC AND GENETIC MARKERS OF RISK: ASPECTS OF CROHN'S DISEASE THAT ARE SHARED BY UNAFFECTED SIBLINGS.GUT vol. 61, A22-A23.
10.1136/gutjnl-2012-302514a.51
Hedin CR, Louis P, Farquharson F et al. (2012) . PREBOTICS AS PRIMARY PREVENTION OF CROHN'S DISEASE: IMPACT ON LUMINAL MICROBIOLOGY AND ELEVATED FAECAL CALPROTECTIN IS GREATER IN HEALTHY SIBLINGS THAN IN PATIENTS.GUT vol. 61, A171-A171.
10.1136/gutjnl-2012-302514b.237
Sanders TJ, McCarthy NE, Giles EM et al. (2012) . THE ROLE OF RDH10 AND RALDH ENZYMES IN RETINOIC ACID-MEDIATED IMMUNE REGULATION BY ANTIGEN PRESENTING CELLS IN THE HUMAN INTESTINE. GUT. vol. 61, A402-A403.
10.1136/gutjnl-2012-302514d.257
Benjamin JL, Hedin CRH, Koutsoumpas A et al. (2012) . Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota.INFLAMMATORY BOWEL DISEASES vol. 18, (6) 1092-1100.
10.1002/ibd.21864
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15332
Hedin CR, Stagg AJ, Whelan K et al. (2012) . Family studies in Crohn's disease: new horizons in understanding disease pathogenesis, risk and prevention.Gut vol. 61, (2) 311-318.
10.1136/gut.2011.238568
Ng SC, Benjamin JL, McCarthy NE et al. (2011) . Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease.Inflamm Bowel Dis vol. 17, (10) 2027-2037.
10.1002/ibd.21590
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15335
Benjamin JL, Hedin CRH, Koutsoumpas A et al. (2011) . Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease.Gut vol. 60, (7) 923-929.
10.1136/gut.2010.232025
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15338
Hedin CR, McCarthy NE, Bhattacharjee S et al. (2011) . V Delta 2+T CELL EXPANSION IN CROHN'S DISEASE: IMPACT OF INFLAMMATION, DISEASE ACTIVITY AND TREATMENT. GUT. vol. 60,
10.1136/gut.2011.239301.314
Ng SC, Benjamin JL, McCarthy NE et al. (2010) . Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease. Inflamm Bowel Dis.
10.1002/ibd.21590
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15336
Al-Hassi HO, Murugananthan A, Bernardo DO et al. (2010) . CCR7-induced homing of human gut dendritic cells mediated by LepRb; differences between ileum and colon and in Crohn's disease. IMMUNOLOGY. vol. 131, 161-162.
McCarthy NE, Hedin CRH, Bhattacharjee S et al. (2010) . Circulating 'gut-tropic' V delta 2 T-cells are expanded in some Crohn's disease patients and their siblings but are ablated by azathioprine therapy. IMMUNOLOGY. vol. 131, 107-107.
Sanders T, McCarthy N, Gellatly N et al. (2010) . Factors from inflamed human intestinal mucosa act on dendritic cells to uncouple the imprinting of gut tropism from FoxP(3)(+) T cell generation. IMMUNOLOGY. vol. 131, 30-31.
Sanders T, McCarthy N, Gellatly N et al. (2010) . Factors from inflamed human intestinal mucosa act on dendritic cells to uncouple the imprinting of gut tropism from FoxP3(+) T cell generation. IMMUNOLOGY. vol. 131, 134-135.
Mann ER, Bernardo D, Al-Hassi HO et al. (2010) . Human dendritic cell function is dependent on tissue of residence. IMMUNOLOGY. vol. 131, 40-40.
Hedin CRH, Mullard M, Sharratt E et al. (2010) . Probiotic and prebiotic use in patients with inflammatory bowel disease: a case-control study.Inflamm Bowel Dis vol. 16, (12) 2099-2108.
10.1002/ibd.21286
Gellatly NL, Sanders TJ, Ahmed M et al. (2010) . Retinoic acid and aryl hydrocarbon receptor signalling: opposing effects on human dendritic cell differentiation and ability to imprint gut homing. IMMUNOLOGY. vol. 131, 155-155.
Groves K, Bibby D, Clark D et al. (2010) . Disease Progression Despite Suppressed Plasma Viral Load in Human Immunodeficiency Infected Viremic Controllers. AIDS RESEARCH AND HUMAN RETROVIRUSES. vol. 26, A163-A163.
Vossenkämper A, Marchès O, Fairclough PD et al. (2010) . Inhibition of NF-κB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE.J Immunol vol. 185, (7) 4118-4127.
10.4049/jimmunol.1000500
Ng SC, Kamm MA, Stagg AJ et al. (2010) . Intestinal dendritic cells: their role in bacterial recognition, lymphocyte homing, and intestinal inflammation.Inflamm Bowel Dis vol. 16, (10) 1787-1807.
10.1002/ibd.21247
Ng SC, Plamondon S, Kamm MA et al. (2010) . Immunosuppressive effects via human intestinal dendritic cells of probiotic bacteria and steroids in the treatment of acute ulcerative colitis.Inflamm Bowel Dis vol. 16, (8) 1286-1298.
10.1002/ibd.21222
Price CL, Hassi HOSA, English NR et al. (2010) . Methylglyoxal modulates immune responses: relevance to diabetes.J Cell Mol Med vol. 14, (6B) 1806-1815.
10.1111/j.1582-4934.2009.00803.x
Benjamin JL, Koutsoumpas A, Hedin CRH et al. (2010) . DEMOGRAPHIC, CLINICAL AND GENETIC FACTORS ASSOCIATED WITH DYSBIOSIS IN PATIENTS WITH ACTIVE CROHN'S DISEASE. GUT. vol. 59, A5-A5.
10.1136/gut.2009.208934k
Benjamin JL, Hedin CRH, Koutsoumpas A et al. (2010) . NO CLINICAL BENEFIT OF PREBIOTICS IN THE TREATMENT OF ACTIVE CROHN'S DISEASE: A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED TRIAL. GUT. vol. 59, A1-A2.
10.1136/gut.2009.208934c
Ng SC, Plamondon S, Al-Hassi HO et al. (2009) . A novel population of human CD56+ human leucocyte antigen D-related (HLA-DR+) colonic lamina propria cells is associated with inflammation in ulcerative colitis.Clin Exp Immunol vol. 158, (2) 205-218.
10.1111/j.1365-2249.2009.04012.x
Mann ER, McCarthy NE, Milestone AN et al. (2009) . LOSS OF HUMAN GAMMA DELTA T-CELLS IN CROHN'S DISEASE AND ULCERATIVE COLITIS. GUT. vol. 58, A61-A61.
Ng SC, Hart AL, Kamm MA et al. (2009) . Mechanisms of action of probiotics: recent advances.Inflamm Bowel Dis vol. 15, (2) 300-310.
10.1002/ibd.20602
Groves KC, Bibby D, Isaksen A et al. (2009) . Altered T cell homeostasis and activation in HIV-1 elite suppressors with low CD4+T-cell counts.RETROVIROLOGY vol. 6, Article P250,
Gellatly NL, Knight SC, Stagg AJ (2008) . Dendritic cell (DC) imprinting of homing markers on human T-cells is modulated by bacteria. IMMUNOLOGY. vol. 125, 23-23.
Mann ER, McCarthy NE, Hart AL et al. (2008) . Distinct gut and skin homing phenotypes of human dendritic cells and T-cells. IMMUNOLOGY. vol. 125, 22-23.
Ng SC, Plamondon S, Kamm MA et al. (2008) . Dysregulated gut homing in patients with ulcerative colitis is associated with altered CD103 (alpha-E) expression by human colonic dendritic cells. IMMUNOLOGY. vol. 125, 23-23.
Mann ER, McCarthy NE, Hart AL et al. (2008) . Loss of human gamma delta T-cells in Crohn's disease and ulcerative colitis. IMMUNOLOGY. vol. 125, 104-104.
Ng SC, Plamondon S, Hart AL et al. (2008) . Oral probiotic bacteria, VSL#3, is associated with the down-regulation of pro-inflammatory cytokine production by gut dendritic cells in patients with ulcerative colitis. IMMUNOLOGY. vol. 125, 129-129.
Ng SC, McCarthy NE, Plamondon S et al. (2008) . TNF-alpha production and differential release of Th1/Th2 cytokines from gut biopsies is associated with 'trauma responses' in inflammatory bowel disease but not in controls. IMMUNOLOGY. vol. 125, 96-96.
Al-Hassi HO, Price CL, Hart AL et al. (2008) . The expression of ILT3 upregulated on DC from inflamed mucosa: role for probiotic bacteria. IMMUNOLOGY. vol. 125, 110-110.
Arebi N, Gurmany S, Bullas D et al. (2008) . Review article: the psychoneuroimmunology of irritable bowel syndrome--an exploration of interactions between psychological, neurological and immunological observations.Aliment Pharmacol Ther vol. 28, (7) 830-840.
10.1111/j.1365-2036.2008.03801.x
Bedford PA, Burke F, Stagg AJ et al. (2008) . Dendritic cells derived from bone marrow cells fail to acquire and present major histocompatibility complex antigens from other dendritic cells.Immunology vol. 124, (4) 542-552.
10.1111/j.1365-2567.2008.02808.x
Ng SC, Koutsoumpas A, Hedin CR et al. (2008) . Production of IL-10 by colonic dendritic cells is associated with higher concentrations of faecal microbiota in patients with active Crohn's disease.GASTROENTEROLOGY vol. 134, (4) A653-A654.
Koutsoumpas A, Hedin CR, Ng SC et al. (2008) . The concentration and proportion of key bacterial groups of the faecal microbiota are different between smokers and non-smokers with active Crohn's disease.GASTROENTEROLOGY vol. 134, (4) A497-A497.
Hedin CRH, Koutsoumpas A, Forbes A et al. (2008) . Factors that limit recruitment to clinical trials in crohn's disease. GUT. vol. 57, A118-A118.
Ng SC, Koutsoumpas A, Hedin CR et al. (2008) . Production of il-10 by colonic dendritic cells is associated with higher concentrations of faecal microbiota in patients with active crohn's disease. GUT. vol. 57, A144-A144.
Koutsoumpas A, Hedin CRH, Ng SC et al. (2008) . Smokers with active crohn's disease have differences in the concentration and proportion of key bacterial groups of the faecal microbiota. GUT. vol. 57, A152-A153.
Di Sabatino A, Pickard KM, Gordon JN et al. (2007) . Evidence for the role of interferon-alfa production by dendritic cells in the Th1 response in celiac disease.Gastroenterology vol. 133, (4) 1175-1187.
10.1053/j.gastro.2007.08.018
http://qmro.qmul.ac.uk/xmlui/handle/123456789/2040
Ng SC, Plamondon S, Knight SC et al. (2007) . Accumulation of plasmacytoid dendritic cells in the intestine of acute ulcerative colitis. GUT. vol. 56, A116-A116.
McCarthy NE, Jones HA, Marks NA et al. (2007) . Inhaled allergen-driven CD1c up-regulation and enhanced antigen uptake by activated human respiratory-tract dendritic cells in atopic asthma.Clin Exp Allergy vol. 37, (1) 72-82.
10.1111/j.1365-2222.2006.02631.x
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15347
Critchley-Thorne RJ, Stagg AJ, Vassaux G (2006) . Recombinant Escherichia coli expressing invasin targets the Peyer's patches: the basis for a bacterial formulation for oral vaccination.Mol Ther vol. 14, (2) 183-191.
10.1016/j.ymthe.2006.01.011
Lindsay JO, Whelan K, Stagg AJ et al. (2006) . Clinical, microbiological, and immunological effects of fructo-oligosaccharide in patients with Crohn's disease.Gut vol. 55, (3) 348-355.
10.1136/gut.2005.074971
McCarthy NE, Jones HA, Marks NA et al. (2005) . Enhanced CD1 expression by activated human respiratory tract dendritic cells in atopic asthma: a role for lipid antigen in allergen tolerance?. IMMUNOLOGY. vol. 116, 22-22.
Al-Hassi HO, Lindsay JO, Whelan K et al. (2005) . Modulation of intestinal dendritic cells (DC) in Crohn's disease patients taking a fructo-oligosaccharide prebiotic.IMMUNOLOGY vol. 116, 4-4.
Stagg AJ, Rigby R, Al-Hassi HO et al. (2005) . Polarisation of T lymphocyte homing by dendritic cells in health and intestinal disease.IMMUNOLOGY vol. 116, 27-28.
Hart AL, Al-Hassi HO, Rigby RJ et al. (2005) . Characteristics of intestinal dendritic cells in inflammatory bowel diseases.Gastroenterology vol. 129, (1) 50-65.
10.1053/j.gastro.2005.05.013
Mason MR, Stagg AJ, Knight SC et al. (2005) . The measurement of dendritic cells in umbilical cord blood: a novel technique using small volumes of whole blood.J Soc Gynecol Investig vol. 12, (4) 246-252.
10.1016/j.jsgi.2004.12.003
Lindsay JO, Whelan K, Stagg A et al. (2005) . Prebiotic fructo-oligosaccharide as a therapy for Crohn's disease: An open label trial. GUT. vol. 54, A23-A24.
Rigby RJ, Knight SC, Kamm MA et al. (2005) . Production of interleukin (IL)-10 and IL-12 by murine colonic dendritic cells in response to microbial stimuli.Clin Exp Immunol vol. 139, (2) 245-256.
10.1111/j.1365-2249.2004.02674.x
Hart AL, Lammers K, Brigidi P et al. (2004) . Modulation of human dendritic cell phenotype and function by probiotic bacteria.Gut vol. 53, (11) 1602-1609.
10.1136/gut.2003.037325
Hart AL, Kamm MA, Knight SC et al. (2004) . Prospective evaluation of intestinal homing memory T cells in ulcerative colitis.INFLAMM BOWEL DIS vol. 10, (5) 496-503.
10.1097/00054725-200409000-00002
Burke F, Stagg AJ, Bedford PA et al. (2004) . IL-10-producing B220+CD11c- APC in mouse spleen.J Immunol vol. 173, (4) 2362-2372.
10.4049/jimmunol.173.4.2362
Lammers KM, Hart AL, Brigidi P et al. (2004) . DNA derived from probiotic bacteria modulates human dendritic cell phenotype and function. GUT. vol. 53, A65-A65.
Hart AL, Al-Hassi HO, Kamm MA et al. (2004) . Dendritic cells may drive proinflammatory T cell immune responses in Crohn's disease by production of IL-12 and IL-6. GUT. vol. 53, A97-A98.
Stagg AJ, Hart AL, Knight SC et al. (2004) . Interactions between dendritic cells and bacteria in the regulation of intestinal immunity.BEST PRACT RES CL GA vol. 18, (2) 255-270.
10.1053/ybega.2004.441
Stagg AJ, Hart AL, Knight SC et al. (2004) . Microbial-gut interactions in health and disease. Interactions between dendritic cells and bacteria in the regulation of intestinal immunity.Best Pract Res Clin Gastroenterol vol. 18, (2) 255-270.
10.1016/j.bpg.2003.10.004
Hart AL, Al-Hassi HO, Kamm MA et al. (2004) . Toll like receptors 2 and 4 are upregulated on human lamina propria dendritic cells in intestinal inflammation. GUT. vol. 53, A3-A3.
Hart AL, Kamm MA, Knight SC et al. (2004) . Quantitative and functional characteristics of intestinal-homing memory T cells: analysis of Crohn's disease patients and healthy controls.CLIN EXP IMMUNOL vol. 135, (1) 137-145.
10.1046/j.1365-2249.2004.02347.x
Stagg AJ, Hart AL, Knight SC et al. (2003) . The dendritic cell: its role in intestinal inflammation and relationship with gut bacteria.Gut vol. 52, (10) 1522-1529.
10.1136/gut.52.10.1522
Hart AL, Kamm MA, Knight SC et al. (2003) . The maturation and cytokine expression of human dendritic cells are differentially modulated by probiotic bacteria. GUT. vol. 52, A56-A57.
Hart AL, Stagg AJ, Kamm MA (2003) . Use of probiotics in the treatment of inflammatory bowel disease.J Clin Gastroenterol vol. 36, (2) 111-119.
10.1097/00004836-200302000-00005
Hart AL, Stagg AJ, Frame M et al. (2002) . Review article: the role of the gut flora in health and disease, and its modification as therapy.ALIMENT PHARM THERAP vol. 16, (8) 1383-1393.
10.1046/j.1365-2036.2002.01310.x
Stagg AJ, Kamm MA, Knight SC (2002) . Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin.Eur J Immunol vol. 32, (5) 1445-1454.
10.1002/1521-4141(200205)32:5<1445::AID-IMMU1445>3.0.CO;2-E
Hart AL, Rigby R, Jones A et al. (2002) . Circulating mucosal homing (beta 7+) memory T cells are decreased in number and display altered cytokine production in Crohn's disease.GUT vol. 50, A74-A74.
Rigby RJ, Hart AL, Westcott EDA et al. (2002) . Identification of possible gut homing dendritic cells in peripheral blood by expression of B7 integrin.GUT vol. 50, A67-A67.
Stagg AJ, Kamm MA, Knight SC (2002) . Intestinal dendritic cells increase T cell expression of alpha 4 beta 7 integrin.GUT vol. 50, A26-A27.
Rigby R, Kamm MA, Knight SC et al. (2002) . Pathogenic bacteria stimulate colonic dendritic cells to produce pro-inflammatory IL-12 while the response to probiotic bacteria is to produce anti-inflammatory IL-10.GUT vol. 50, A70-A70.
Hart AL, Rigby R, Stagg AJ et al. (2002) . Probiotic bacteria stimulate natural killer (NK) cell activation and cytokine production, an early step in innate immunity.GUT vol. 50, A69-A69.
Hart AL, Stagg AJ, Rigby R et al. (2002) . Streptococcus faecium, a possible probiotic bacterium, but not Lactobacillus acidophilus or Escherichia coli (Nissle), decreases proinflammatory cytokine production (IFN-Gamma) by an IL-10 dependent mechanism.GUT vol. 50, A67-A67.
Jebbari H, Stagg AJ, Davidson RN et al. (2002) . Leishmania major promastigotes inhibit dendritic cell motility in vitro.Infect Immun vol. 70, (2) 1023-1026.
10.1128/IAI.70.2.1023-1026.2002
Bell SJ, Rigby R, English N et al. (2001) . Migration and maturation of human colonic dendritic cells.J Immunol vol. 166, (8) 4958-4967.
10.4049/jimmunol.166.8.4958
Stagg AJ, Burke F, Hill S et al. (2001) . Isolation of mouse spleen dendritic cells.Methods Mol Med vol. 64, 9-22.
10.1385/1-59259-150-7:9
MCCARTHY NE, Tyler CJ, Lindsay JO et al.. Antigen-presenting human γδ T-cells promote intestinal CD4+ T-cell expression of IL-22 and mucosal release of calprotectin.Journal of Immunology
10.4049/jimmunol.1700003
http://qmro.qmul.ac.uk/xmlui/handle/123456789/19499
STAGG AJ, Giles EM, Sanders TJ et al.. Regulation of human intestinal T-cell responses by Type 1 interferon-STAT1 signalling is disrupted in inflammatory bowel disease.Mucosal Immunology
10.1038/mi.2016.44
http://qmro.qmul.ac.uk/xmlui/handle/123456789/12894
Return to top