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Publications:  Prof Ian Sanderson

Pathak SJ, Mueller JL, Okamoto K, Das B, Hertecant J, Greenhalgh L, Cole T, Pinsk V et al.(2019). EPCAM mutation update: Variants associated with congenital tufting enteropathy and Lynch syndrome. Hum Mutat vol. 40, (2) 142-161.
10.1002/humu.23688
Flemer B, Gaci N, Borrel G, Sanderson IR, Chaudhary PP, Tottey W, O'Toole PW, Brugère J-F(2017). Fecal microbiota variation across the lifespan of the healthy laboratory rat. Gut Microbes vol. 8, (5) 428-439.
10.1080/19490976.2017.1334033
Amon P, Serena G, Fasano A, Walker A, Wade W, Sanderson I (2017). EXCLUSIVE ENTERAL NUTRITION MODULATES THE MICROBIOTA IN CHILDHOOD CROHN'S DISEASE INDEPENDENTLY OF ITS EFFECT ON INTESTINAL INFLAMMATION. GASTROENTEROLOGY. vol. 152, S214-S214.
10.1016/S0016-5085(17)31018-1
Amon P, Sanderson I(2017). What is the microbiome?. Archives of Disease in Childhood: Education and Practice Edition
10.1136/archdischild-2016-311643
Rampton DS, Goodhand JR, Joshi NM, Karim A-B, Koodun Y, Barakat FM, Macken L, Ward DG et al.(2016). Oral Iron Treatment Response and Predictors in Anaemic Adolescents and Adults with IBD: A Prospective Controlled Open-Label Trial. Journal of Crohn's and Colitis
10.1093/ecco-jcc/jjw208
SANDERSON IR, Altowati MA, Jones AP, Hickey H, Williamson PR, Barakat FM, Plaatjies NC, Hardwick B et al.(2016). Assessing the feasibility of injectable growth-promoting therapy in Crohn’s disease. Pilot and Feasibility Studies vol. 2, 71-71.
10.1186/s40814-016-0112-9
Goodhand J, Rampton D, Joshi N, Karim A-B, Koodun Y, Macken L, Baraket F, Epstein J et al. (2016). CLINICAL TRIAL: EFFECTS OF ORAL FERROUS SULPHATE ON HAEMOGLOBIN, HEPCIDIN, DISEASE ACTIVITY, MOOD AND QUALITY OF LIFE IN ADOLESCENTS AND ADULTS WITH IRON DEFICIENCY ANAEMIA DUE TO IBD. GUT. vol. 65, A251-A251.
10.1136/gutjnl-2016-312388.472
McCarthy NE, Hedin CR, Sanders TJ, Amon P, Hoti I, Ayada I, Baji V, Giles EM et al.(2015). Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease. Journal of Clinical Investigation vol. 125, (8) 3215-3225.
10.1172/JCI80840
McCarthy NE, Hedin CR, Sanders TJ, Amon P, Baji V, Giles EM, Wildemann M, Bashir Z et al. (2014). Colonic V delta 2+T-cells display elevated TNF production and reversible ablation by azathioprine therapy in Crohn's disease. IMMUNOLOGY. vol. 143, 165-165.
Giles E, Sanders TJ, McCarthy NE, Sanderson I, Lindsay J, MacDonald TT, Stagg AJ (2014). Constitutive Type I Interferon, via STAT1 activation, selectively promotes regulatory T cell function in the healthy human intestine, but not in IBD. IMMUNOLOGY. vol. 143, 17-17.
Sanderson IR(2014). Growth problems in children with IBD. Nat Rev Gastroenterol Hepatol vol. 11, (10) 601-610.
10.1038/nrgastro.2014.102
Giles E, Pathak M, Sanders TJ, McCarthy NE, Sanderson IR, Thomas M, Lindsay JO, Stagg AJ (2014). Constitutive Type I Interferon, via STAT1 Activation, Selectively Promotes Regulatory T Cell Function in the Healthy Human Intestine, but Not in Inflammatory Bowel Disease. GASTROENTEROLOGY. vol. 146, S293-S294.
Dogra H, Peiris M, Robinow AD, Blackshaw A, Sanderson IR (2014). Nutrient-Induced Reduction of IL-8 Release in Paediatric Human Ascending Colon. GASTROENTEROLOGY. vol. 146, S783-S783.
Li Y, Teo WL, Low MJ, Meijer L, Sanderson I, Pettersson S, Greicius G(2014). Constitutive TLR4 signalling in intestinal epithelium reduces tumor load by increasing apoptosis in APC(Min/+) mice. Oncogene vol. 33, (3) 369-377.
10.1038/onc.2012.581
Li S, Symonds ALJ, Miao T, Sanderson I, Wang P(2014). Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer. Front Immunol vol. 5,
10.3389/fimmu.2014.00293
Giles E, Pathak M, Sanders TJ, McCarthy NE, Sanderson IR, MacDonald TT, Lindsay JO, Stagg AJ (2013). Constitutive Type I Interferon, via STAT1 activation, promotes regulatory T cell function in the healthy human intestine, but not in inflammatory bowel disease. IMMUNOLOGY. vol. 140, 168-168.
Sylvester FA, Gordon CM, Thayu M, Burnham JM, Denson LA, Essers J, Ferrari S, Gupta N et al.(2013). Report of the CCFA pediatric bone, growth and muscle health workshop, New York City, November 11-12, 2011, with updates. Inflamm Bowel Dis vol. 19, (13) 2919-2926.
10.1097/MIB.0b013e3182a5a004
Queiroz DMM, Harris PR, Sanderson IR, Windle HJ, Walker MM, Rocha AMC, Rocha GA, Carvalho SD et al.(2013). Iron status and Helicobacter pylori infection in symptomatic children: an international multi-centered study. PLoS One vol. 8, (7)
10.1371/journal.pone.0068833
Rao A, Standing JF, Naik S, Savage MO, Sanderson IR(2013). Mathematical modelling to restore circulating IGF-1 concentrations in children with Crohn's disease-induced growth failure: a pharmacokinetic study. BMJ Open vol. 3, (5) Article e002737,
10.1136/bmjopen-2013-002737
Rao A, Kamperidis N, Koodun Y, Naik S, Croft NM, Sanderson IR (2012). RESPONSE TO ENTERAL NUTRITION PREDICTS INCREASED LENGTH OF REMISSION IN CHILDREN WITH CROHN'S DISEASE. GUT. vol. 61, A239-A239.
10.1136/gutjnl-2012-302514c.131
Kamperidis N, Goodhand JR, Chowdhury FA, Koodun Y, Direzke NC, Naik S, Sanderson IR, Croft NM et al.(2012). Factors associated with nonadherence to thiopurines in adolescent and adult patients with inflammatory bowel disease. J Pediatr Gastroenterol Nutr vol. 54, (5) 685-689.
10.1097/MPG.0b013e3182475e71
Arribas B, Garrido-Mesa N, Perán L, Camuesco D, Comalada M, Bailón E, Olivares M, Xaus J et al.(2012). The immunomodulatory properties of viable Lactobacillus salivarius ssp. salivarius CECT5713 are not restricted to the large intestine. Eur J Nutr vol. 51, (3) 365-374.
10.1007/s00394-011-0221-4
Goodhand JR, Kamperidis N, Rao A, Laskaratos F, McDermott A, Wahed M, Naik S, Croft NM et al.(2012). Prevalence and management of anemia in children, adolescents, and adults with inflammatory bowel disease. Inflamm Bowel Dis vol. 18, (3) 513-519.
10.1002/ibd.21740
Raymond M, Marchbank T, Moyer MP, Playford RJ, SANDERSON IR, Kruidenier L(2012). IL-1β stimulation of CCD-18co myofibroblasts enhances repair of epithelial monolayers through Wnt-5a. American Journal of Physiology: Gastrointestinal and Liver Physiology
10.1152/ajpgi.00458.2011
Rao A, Mellerio JE, Sklar M, Brain C, Allgrove J, Sanderson IR, Martinez AE(2011). GROWTH IMPAIRED CHILDREN WITH EPIDERMOLYSIS BULLOSA HAVE INCREASED SERUM MARKERS OF INFLAMMATION AND REDUCED CIRCULATING IGF-1/IGFBP-3. PEDIATRIC RESEARCH vol. 70, 294-294.
10.1038/pr.2011.519
Queiroz DMM, Harris P, Sanderson I, Rocha AMC, Rocha GA, Villagran A, Walker MM, Windle H et al. (2011). IRON DEFICIENCY ANAEMIA (IDA) AND H. PYLORI INFECTION IN CHILDREN: A MULTICENTERED STUDY. HELICOBACTER. vol. 16, 109-110.
Queiroz DMM, Harris P, Sanderson IR, Rocha AMC, Rocha GA, Villagran A, Thomson M, Windle H et al. (2011). THE PREVALENCE OF H. PYLORI INFECTION REMAINS HIGH IN CHILDREN FROM DEVELOPING COUNTRIES. HELICOBACTER. vol. 16, 86-86.
Goodhand JR, Tshuma N, Rao A, Kotta S, Wahed M, Croft NM, Sanderson IR, Epstein J et al.(2011). Do children with IBD really respond better than adults to thiopurines?. J Pediatr Gastroenterol Nutr vol. 52, (6) 702-707.
10.1097/MPG.0b013e31820ba46c
Rao A, Naik S, Savage MO, Sanderson IR (2011). Subcutaneous rhIGF-1 Significantly Increases Circulating IGF-1 Concentrations in Children With Crohn's Disease Induced Growth Failure. GASTROENTEROLOGY. vol. 140, S508-S508.
Rao A, Naik S, Savage MO, Sanderson IR (2011). SUBCUTANEOUS RHIGF-1 SIGNIFICANTLY INCREASES CIRCULATING IGF-1 CONCENTRATIONS IN CHILDREN WITH CROHN'S DISEASE INDUCED GROWTH FAILURE. GUT. vol. 60,
10.1136/gut.2011.239301.35
Dhaliwal W, Shawa T, Khanam M, Jagatiya P, Simuyandi M, Ndulo N, Bevins CL, Sanderson IR et al.(2010). Intestinal antimicrobial gene expression: impact of micronutrients in malnourished adults during a randomized trial. J Infect Dis vol. 202, (6) 971-978.
10.1086/655903
Kelly P, Shawa T, Mwanamakondo S, Soko R, Smith G, Barclay GR, Sanderson IR(2010). Gastric and intestinal barrier impairment in tropical enteropathy and HIV: limited impact of micronutrient supplementation during a randomised controlled trial. BMC Gastroenterol vol. 10,
10.1186/1471-230X-10-72
Epstein J, Sanderson IR, Macdonald TT(2010). Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies. Br J Nutr vol. 103, (11) 1545-1557.
10.1017/S0007114509993667
Rao A, Tshuma NB, Goodhand JR, Wahed M, Croft NM, Epstein J, Sanderson IR (2010). RESPONSE TO AZATHIOPRINE IN ADULTS AND CHILDREN WITH INFLAMMATORY BOWEL DISEASE IS COMPARABLE WHEN PHENOTYPE IS CONTROLLED. J PEDIATR GASTR NUTR. vol. 50, E112-E112.
Epstein J, Docena G, MacDonald TT, Sanderson IR(2010). Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1beta and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease. Br J Nutr vol. 103, (6) 824-832.
10.1017/S0007114509992510
Kelly P, Dhaliwal W, Shawa T, Sanderson I (2009). EXPRESSION OF SMALL INTESTINAL ANTIMICROBIAL GENES IN ZAMBIAN ADULTS: A RANDOMISED CONTROLLED TRIAL OF MICRONUTRIENT SUPPLEMENTATION. GUT. vol. 58, A118-A119.
Kelly P, Shawa T, Sanderson I (2009). GASTRIC HYPOCHLORHYDRIA AND INTESTINAL BARRIER DYSFUNCTION IN HIV INFECTION IS NOT DEPENDENT ON NUTRITION: A RANDOMISED CONTROLLED TRIAL OF SUPPLEMENTATION. GUT. vol. 58, A82-A83.
Kelly P, Katubulushi M, Todd J, Banda R, Yambayamba V, Fwoloshi M, Zulu I, Kafwembe E et al.(2008). Micronutrient supplementation has limited effects on intestinal infectious disease and mortality in a Zambian population of mixed HIV status: a cluster randomized trial. AM J CLIN NUTR vol. 88, (4) 1010-1017.
10.1093/ajcn/88.4.1010
Naik S, Smith F, Ho J, Croft NM, Domizio P, Price E, Sanderson IR, Meadows NJ(2008). Staphylococcal enterotoxins G and I, a cause of severe but reversible neonatal enteropathy. CLIN GASTROENTEROL H vol. 6, (2) 251-254.
10.1016/j.cgh.2007.09.004
SANDERSON I, Sanderson IR(2008). Dietary regulation of gene expression. Gastroenterology and Nutrition: Neonatology questions and controversies, Editors: Neu, J, Edition. 1st, Saunders (Philadelphia (PA)),
SANDERSON I, Bajaj-Elliott M(2008). Nutrition and gene expression. Nutrition in Pediatrics, Editors: Duggan, C, Watkins, JB, Walker, WA, B C Decker (Hamilton (ON)),
SANDERSON I, Kleinman RA, Goulet O, Mieli-Vergani G, Sanderson IR, Schneider BL, Sherman PM(2008). Walker's pediatric gastrointestinal disease : physiology, diagnosis, management. BC Decker (Hamilton Ont.),
Weng M, Walker WA, Sanderson IR(2007). Butyrate regulates the expression of pathogen-triggered IL-8 in intestinal epithelia. PEDIATR RES vol. 62, (5) 542-546.
10.1203/PDR.0b013e318155a422
Sanderson IR(2007). Dietary modulation of GALT. J Nutr vol. 137, (11 Suppl) 2557S-2562S.
10.1093/jn/137.11.2557S
Daley A, Randall R, Darsley M, Choudhry N, Thomas N, Sanderson IR, Croft NM, Kelly P(2007). Genetically modified enterotoxigenic Escherichia coli vaccines induce mucosal immune responses without inflammation. Gut vol. 56, (11) 1550-1556.
10.1136/gut.2006.112805
Koglmeier J, Meadows N, Naik S, Sanderson I, Croft N(2007). Contribution of repeat colonoscopies to clinical management in children with inflammatory bowel disease. J PEDIATR GASTR NUTR vol. 44, 108-108.
Sebastian M, Mohamed A, Sanderson IR, Kruidenier L (2007). Myofibroblast Wnt-5A facilitates intestinal epithelial repair through a non-canonical pathway. GUT. vol. 56, A39-A39.
Sebastian M, Mohamed A, Wilson JW, Galvez J, Sanderson IR, Kruidenier L (2007). Myofibroblast Wnt-5a facilitates intestinal epithelial repair through a non-canonical pathway. GASTROENTEROLOGY. vol. 132, A710-A710.
Lottaz D, Buri C, Monteleone G, Rosmann S, MacDonald TT, Sanderson IR, Sterchi EE(2007). Compartmentalised expression of meprin in small intestinal mucosa: enhanced expression in lamina propria in coeliac disease. BIOL CHEM vol. 388, (3) 337-341.
10.1515/BC.2007.038
Sanderson IR, Walker WA(2007). TLRs in the Gut I. The role of TLRs/Nods in intestinal development and homeostasis. Am J Physiol Gastrointest Liver Physiol vol. 292, (1) G6-10.
10.1152/ajpgi.00275.2006
Sawczenko A, Ballinger AB, Savage MO, Sanderson IR(2006). Clinical features affecting final adult height in patients with pediatric-onset Crohn's disease. PEDIATRICS vol. 118, (1) 124-129.
10.1542/peds.2005-2931
Mulligan P, White NRJ, Monteleone G, Wang P, Wilson JW, Ohtsuka Y, Sanderson IR(2006). Breast milk lactoferrin regulates gene expression by binding bacterial DNA CpG motifs but not genomic DNA promoters in model intestinal cells. PEDIATR RES vol. 59, (5) 656-661.
10.1203/01.pdr.0000214958.80011.e1
Weng MQ, Walker W, Sanderson I (2006). Butyrate up-regulates the bacterial lipoprotein stimulation of the NF kappa B inhibitory protein A20, in intestinal epithelial cells. GASTROENTEROLOGY. vol. 130, A609-A609.
Manzo BA, Crabtree JE, Fiona Campbell M, Tweedle D, Potten CS, Bajaj-Elliott M, Sanderson IR, Wilson JW(2006). Helicobacter pylori regulates the expression of inhibitors of DNA binding (Id) proteins by gastric epithelial cells. Microbes Infect vol. 8, (4) 1064-1074.
10.1016/j.micinf.2005.11.003
Afzal NA, Hans-Joerg L, Mills S, Green M, Naik S, Meadows N, Sanderson I, Croft N (2006). Inflammatory bowel disease phenotype in British children of South Asian origin. GASTROENTEROLOGY. vol. 130, A215-A215.
Yap LM, Lottaz D, Ahmad T, Zhang L, Van Heel D, McGovern D, Negoro K, Sterchi E et al. (2006). Polymorphism in the MEP1A gene: A role in IBD?. INFLAMMATORY BOWEL DISEASES. vol. 12, S19-S19.
10.1097/00054725-200604002-00038
Levi RS, Kruidenier L, Meijer L, Lu XP, Sebastian M, Pettersson S, Sanderson IR (2006). Transgenic epithelial cell toll-like receptor (TLR) signaling reduces inflammation in DSS colitis. GASTROENTEROLOGY. vol. 130, A367-A367.
White NR, Mulligan P, King PJ, Sanderson IR(2006). Sodium butyrate-mediated Sp3 acetylation represses human insulin-like growth factor binding protein-3 expression in intestinal epithelial cells. J Pediatr Gastroenterol Nutr vol. 42, (2) 134-141.
10.1097/01.mpg.0000189345.31010.89
Kruidenier L, MacDonald TT, Collins JE, Pender SLF, Sanderson IR(2006). Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells. Gastroenterology vol. 130, (1) 127-136.
10.1053/j.gastro.2005.09.032
Sanderson IR, Walker WA(2005). Immunology. CURR OPIN GASTROEN vol. 21, (6) 684-686.
10.1097/01.mog.0000183665.41753.84
Sawczenko A, Azooz O, Paraszczuk J, Idestrom M, Croft NM, Savage MO, Ballinger AB, Sanderson IR(2005). Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the-174 IL-6 G/C polymorphism in children. P NATL ACAD SCI USA vol. 102, (37) 13260-13265.
10.1073/pnas.0503589102
Abdalla SI, Sanderson IR, Fitzgerald RC(2005). Effect of inflammation on cyclooxygenase (COX)-2 expression in benign and malignant oesophageal cells. CARCINOGENESIS vol. 26, (9) 1627-1633.
10.1093/carcin/bgi114
Albers R, Antoine JM, Bourdet-Sicard R, Calder PC, Gleeson M, Lesourd B, Samartin S, Sanderson IR et al.(2005). Markers to measure immunomodulation in human nutrition intervention studies. BRIT J NUTR vol. 94, (3) 452-481.
10.1079/BJN20051469
Sanderson IR, Croft NM (2005). The anti-inflammatory effects of enteral nutrition. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION. vol. 29, S134-S140.
10.1177/01486071050290S4S134
Dogra H, Kruidenier L, Croft NM, Sanderson IR, Wilson JW (2005). Butyrate regulates the expression of the intestinal epithelial stem cell marker, Musashi-1. GASTROENTEROLOGY. vol. 128, A279-A279.
Dogra H, Kruidenier L, Sanderson IR, Croft NM, Wilson JW (2005). Luminal regulation of intestinal epithelial stem cell fate. GUT. vol. 54, A78-A78.
Sawczenko A, Idestrom M, Ballinger AB, Croft NM, Sanderson IR (2005). The -174 G/c interleukin-6 polymorphism determines growth failure in paediatric onset Crohn's disease. GASTROENTEROLOGY. vol. 128, A39-A39.
Sawczenko A, Idestrom M, Ballinger AB, Croft NM, Sanderson IR (2005). The-174 G/C interleukin-6 polymorphism determines growth failure in paediatric onset Crohn's disease. GUT. vol. 54, A97-A98.
SANDERSON IR, Morgan M, Baker AJ, Kelly DA(2005). Questionnaire survey of British Society for Paediatric Gastroenterology Hepatology And Nutrition (BSPGHAN) members to examine workload and resources for paediatric gastroenterologists. Arch Dis Child vol. 90,
10.1136/adc.2004.059105
Sanderson IR(2004). Short chain fatty acid regulation of signaling genes expressed by the intestinal epithelium. J Nutr vol. 134, (9) 2450S-2454S.
10.1093/jn/134.9.2450S
Sanderson IR, Bustin SA, Dziennis S, Paraszczuk J, Stamm DS(2004). Age and diet act through distinct isoforms of the class II transactivator gene in mouse intestinal epithelium. GASTROENTEROLOGY vol. 127, (1) 203-212.
10.1053/j.gastro.2004.04.014
SANDERSON IR(2004). Gastrin-induced Cyclooxygenase-2 expression in Barret's carcinogenesis. Clin Cancer Res vol. 10, 4784-4792.
10.1158/1078-0432.CCR-04-0015
Salazar-Lindo E, Allen S, Brewster DR, Elliott EJ, Fasano A, Phillips AD, Sanderson IR, Tarr PI et al. (2004). Intestinal infections and environmental enteropathy: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. vol. 39 Suppl 2, S662-S669.
10.1097/00005176-200406002-00013
Abdalla S, Sirieix PS, Sanderson IR, Fitzgerald RC (2004). Gastrin induces cyclooxygenase (COX)-2 expression in Barrett's oesophagus. GUT. vol. 53, A58-A58.
Manzo BA, Sanderson IR, Wilson JW (2004). Helicobacter pylori express an E2A homologue. GUT. vol. 53, A63-A63.
Manzo BA, Sanderson IR, Wilson JW (2004). Helicobacter pylori express an E2a homologue?. GASTROENTEROLOGY. vol. 126, A409-A409.
Croft NM, Paraszczuk J, Ali E, Wilson JW, Jones SA, Naik S, Sanderson IR (2004). Is there a relationship between NOD2 polymorphism and response to polymeric enteral feed in children with Crohn's disease?. GUT. vol. 53, A32-A32.
Yap LM, Lottaz D, Ahmad T, Zhang L, Van Heel D, McGovern D, Negoro K, Sterchi E et al. (2004). Polymorphisms in the MEP1A gene are not associated with susceptibility to coeliac disease. GUT. vol. 53, A71-A71.
Yap LM, Lottaz D, Ahmad T, Zhang L, Van Heel D, McGovern D, Negoro K, Sterchi E et al. (2004). Polymorphisms in the MEP1A gene: A role in inflammatory bowel disease (IBD)?. GASTROENTEROLOGY. vol. 126, A351-A352.
Abdalla S, Sanderson IR, Novelli MR, Lovat LB, Fitzgerald RC (2004). Variable cyclooxygenase (COX)-2 expression in Barrett's associated adenocarcinoma: Relationship to tumour differentiation. GUT. vol. 53, A58-A58.
Bannerjee T, Camacho-Hubner C, Babinska K, Dryhurst KM, Edwards R, Savage MO, Sanderson IR, Croft NM(2004). Anti-inflammatory and growth-stimulating effects precede nutritional restitution during enteral feeding in Crohn disease. J PEDIATR GASTR NUTR vol. 38, (3) 270-275.
10.1097/00005176-200403000-00007
Levi RS, Sanderson IR(2004). Dietary regulation of gene expression. CURR OPIN GASTROEN vol. 20, (2) 139-142.
10.1097/00001574-200403000-00015
Thapar N, Sanderson IR(2004). Diarrhoea in children: an interface between developing and developed countries. LANCET vol. 363, (9409) 641-653.
10.1016/S0140-6736(04)15599-2
Sanderson IR, WILSON JW, Butler RN, Jones SA(2004). Butyrate and TNF-alpha-induced apoptosis of intestinal epithelial cells: efficacy of specific caspase inhibitors in preventing cell death. Exp. Cell Res. vol. 292, 29-39.
SANDERSON I, Walker WA, Goulet O, Kleinman RA, Sherman PM, Schneider, Sanderson IR(2004). Pediatric Gastrointestinal Disease. BC Decker (Hamilton Ont.),
SANDERSON IR, Bajaj-Elliott M(2004). Structure and function of the gastrointestinal mucosa. Oral Tolerance: the response of the intestinal mucosa to dietary antigens, Editors: Morteau, O, Kluwer Academic
SANDERSON IR, Bajaj-Elliott M, Sanderson IR(2004). Structure and function of the gastrointestinal mucosa. Oral Tolerance: The response of the intestinal mucosa to dietary antigens, Editors: Morteau, O, Landes Biosciences Publishers (Georgetown, TX),
Jones SA, Butler RN, Sanderson IR, Wilson JW(2004). The effect of specific caspase inhibitors on TNF-alpha and butyrate-induced apoptosis of intestinal epithelial cells. EXP CELL RES vol. 292, (1) 29-39.
10.1016/j.yexcr.2003.08.005
Street ME, Miraki-Moud F, Sanderson IR, Savage MO, Giovannelli G, Bernasconi S, Camacho-Hübner C(2003). Interleukin-1beta (IL-1beta) and IL-6 modulate insulin-like growth factor-binding protein (IGFBP) secretion in colon cancer epithelial (Caco-2) cells. J Endocrinol vol. 179, (3) 405-415.
10.1677/joe.0.1790405
Sanderson IR(2003). The innate immune system of the gastrointestinal tract. MOL IMMUNOL vol. 40, (7) 393-394.
10.1016/S0161-5890(03)00159-7
Mulligan P, White NRJ, Monteleone G, Wang P, Wilson JW, Ohtsuka Y, Sanderson IR (2003). Breast milk lactoferrin regulates gene expression by binding to extracellular pro-inflammatory CpG DNA sequences, but not nuclear DNA. GUT. vol. 52, A58-A58.
Mulligan P, White N, Wang P, Wilson J, Sanderson I (2003). Breast milk lactoferrin regulates intestinal gene expression by binding bacterial DNA but not genomic DNA. GASTROENTEROLOGY. vol. 124, A260-A261.
10.1016/S0016-5085(03)81304-5
Croft NM, Ho J, Akanle OA, Savage MO, Sanderson IR (2003). Decreased bone mineral density at diagnosis in paediatric inflammatory bowel disease. GUT. vol. 52, A21-A21.
Kruidenier L, MacDonald TT, Sanderson IR (2003). Fibroblast-derived matrix metalloproteinases activate a potent neutrophil chemoattractant from intestinal epithelial cells. GUT. vol. 52, A57-A57.
Naik S, Wilson JW, Jones S, Sanderson I (2003). For whom the epithelial cell tolls, it tolls for BLP. GASTROENTEROLOGY. vol. 124, A158-A158.
10.1016/S0016-5085(03)80788-6
Manzo BA, Bajaj-Elliott M, Atherton J, Thomas R, Sanderson IR, Wilson JW (2003). Helicobacter pylori regulates Id-1 and Id-3 expression, but not Id-2. GUT. vol. 52, A8-A8.
Manzo BA, Bajaj-Elliott M, Atherton JC, Thomas RJ, Sanderson IR, Wilson JW (2003). Helicobacter pylori regulates expression of ID-1 and ID-3 but not ID-2. GASTROENTEROLOGY. vol. 124, A590-A591.
White NR, Mulligan P, Sanderson IR (2003). Sodium butyrate mediated spa acetylation represses IGFBP-3 expression in intestinal epithelial cells. GASTROENTEROLOGY. vol. 124, A433-A433.
10.1016/S0016-5085(03)82185-6
Naik S, Smith F, Ho J, Croft NM, Domizio P, Price E, Sanderson IR, Meadows NJ (2003). Staphylococcal enterotoxin G and I: A novel cause of severe neonatal enteropathy?. GUT. vol. 52, A101-A101.
Naik Z, Smith F, Ho J, Croft N, Domizio P, Sanderson I, Meadows T, Price E (2003). Staphylococcal enterotoxins G and I: A cause of severe neonatal enteropathy?. GASTROENTEROLOGY. vol. 124, A560-A560.
Kruidenier L, Pender SL, Naik SK, Mongrino R, Collins J, MacDonald TT, Sanderson IR (2003). The neutrophil chemokine NAP-2 is proteolytically activated from intestinal epithelial cells by fibroblast matrix metalloproteinases. GASTROENTEROLOGY. vol. 124, A111-A111.
10.1016/S0016-5085(03)80548-6
Ballinger AB, Savage MO, Sanderson IR(2003). Delayed puberty associated with inflammatory bowel disease. PEDIATR RES vol. 53, (2) 205-210.
10.1203/01.PDR.0000047510.65483.C9
Sanderson IR, Croft NM, SAVAGE MO, Ballinger AB, Sawczenko A(2003). Adult height in patients with early onset of Crohn's disease. [Letter]. Gut. vol. 52, (3) 454-455.
10.1136/gut.52.3.454
Ohtsuka Y, Sanderson IR(2003). Dextran sulfate sodium-induced inflammation is enhanced by intestinal epithelial cell chemokine expression in mice. PEDIATR RES vol. 53, (1) 143-147.
10.1203/01.PDR.0000041519.16507.06
SANDERSON IR(2003). Dietary regulation of immune genes of enterocytes. [Review]. NeoReviews vol. 4, c121-c124.
SANDERSON IR, Chapman MH(2003). Intestinal flora and the mucosal immune system. [Review]. Annales Nestle vol. 61, 55-65.
SANDERSON IR, Bajaj-Elliott M, Sanderson IR(2003). Nutrition and gene expression. Nutrition in Pediatrics - Basic Science and Clinical Aspects, Editors: Walker, WA, Watkins, J, Duggan, C, Edition. 2nd, BC Decker (Ontario, Canada),
SANDERSON IR(2003). The innate immune system of the gastrointestinal tract. [Review]. Mol. Immunol. vol. 40, 393-394.
SANDERSON IR(2003). The physiochemical environment of the neonatal intestine. [Review]. NeoReviews vol. 4, c117-c120.
SANDERSON IR(2003). Vascular endothelial growth factor in human milk. [Review]. NeoReviews vol. 4, c125-c127.
Escher JC, Lindquist B, Hildebrand H, Cezard JP, Derkx B, Ferry G, Grand R, Griffiths A et al.(2002). Budesonide capsules versus prednisolone in children with active Crohn's disease: Results of a European multicenter trial. GASTROENTEROLOGY vol. 122, (4) A12-A12.
Abdalla SI, Sanderson IR, Fitzgerald RC(2002). Cyclooxygenase-2 expression in columnar versus squamous phenotypes: Relationship to oesophageal inflammation and Barrett's oesophagus. GASTROENTEROLOGY vol. 122, (4) A290-A291.
Ali E, Crouchman P, Meadows N, Sanderson IR, Croft NM (2002). Outcome of enteral feeding for newly diagnosed Crohn's disease. GUT. vol. 50, A71-A72.
White NRJ, Mulligan P, Sanderson IR(2002). Sodium butyrate downregulates IGF-binding protein-3 expression in the absence of de novo protein synthesis. GUT vol. 50, A95-A96.
Sanderson IR (2002). Feeding genes. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. vol. 34, S22-S26.
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SANDERSON IR, Thapar N(2002). Intestinal malformations. Current Pediatric Therapy. Burg, FD, Ingelfiniger, JR, Polin, RA, Geshon, AA, Eds., WB Saunders (Philadelphia),
SANDERSON IR, Walker WA(2002). Role of the mucosal barrier in antigen handling by the gut. Food allergy and intolerance, 2nd Ed. Brostoff and Challacombe Eds., Saunders (London),
SANDERSON IR, Mirakian R(2002). The enterocytes. Food allergy and intolerance, 2nd Ed. Brostoff and Challacombe Eds., Saunders (London),
Sanderson IR (2001). Nutritional factors and immune functions of gut epithelium. PROCEEDINGS OF THE NUTRITION SOCIETY. vol. 60, 443-447.
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Ohtsuka Y, Lee J, Stamm DS, Sanderson IR(2001). MIP-2 secreted by epithelial cells increases neutrophil and lymphocyte recruitment in the mouse intestine. GUT vol. 49, (4) 526-533.
10.1136/gut.49.4.526
Kelly EJ, Naik S, Sanderson IR, Croft NM (2001). Elemental diet modulates the inflammatory response of enterocytes. GASTROENTEROLOGY. vol. 120, A674-A675.
Naik S, Meijer L, Pettersen S, Kelly EJ, Sanderson IR (2001). Absence of Toll like receptor 4 (TLR4) explains endotoxin hyporesponsiveness in human intestinal epithelium. GUT. vol. 48, A17-A17.
Croft NM, Kelly EJ, Bannerjee K, Dryhurst K, Sanderson I (2001). Diets can modulate the inflammatory response in vivo and in vitro. GUT. vol. 48, A2-A2.
Naik S, SANDERSON IR, Pettersson S, Meijer L, Kelly EJ(2001). Absence of Toll-like receptor 4 explains endotoxin hyporesponsiveness in human intestinal epithelium. J. Pediatr. Gastroenterol. Nutr. vol. 32, 449-453.
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SANDERSON IR, MacDermott RP(2001). Chemokines: an overview and their relation to chronic idiopathic inflammatory bowel disease. Recent Advances in Histopathology vol. 19, 201-210.
SANDERSON IR, MacDonald TT, Ohtsuka Y(2001). Food intolerance. Nutrition in the Infant - Problems and Practical Procedures. Preedy, V, Grimble, G, Watson, R, eds., Greenwich Medical Media Ltd (London),
Pollok RCG, Farthing MJG, Bajaj-Elliott M, Sanderson IR, McDonald V(2001). Interferon gamma induces enterocyte resistance against infection by the intracellular pathogen Cryptosporidium parvum. GASTROENTEROLOGY vol. 120, (1) 99-107.
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SANDERSON IR (2001). Review of autism research. Medical Research Council (London),
Pender SL, Quinn JJ, Sanderson IR, MacDonald TT(2000). Butyrate upregulates stromelysin-1 production by intestinal mesenchymal cells. Am J Physiol Gastrointest Liver Physiol vol. 279, (5) G918-G924.
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Ohtsuka Y, Sanderson IR(2000). Transforming growth factor-beta: an important cytokine in the mucosal immune response. Curr Opin Gastroenterol vol. 16, (6) 541-545.
10.1097/00001574-200011000-00014
Nanthakumar NN, Fusunyan RD, Sanderson I, Walker WA(2000). Inflammation in the developing human intestine: A possible pathophysiologic contribution to necrotizing enterocolitis. Proc Natl Acad Sci U S A vol. 97, (11) 6043-6048.
10.1073/pnas.97.11.6043
Sanderson IR, Naik S(2000). Dietary regulation of intestinal gene expression. Annu Rev Nutr vol. 20, 311-338.
10.1146/annurev.nutr.20.1.311
Fusunyan RD, Quinn JJ, Fujimoto M, MacDermott RP, Sanderson IR(1999). Butyrate switches the pattern of chemokine secretion by intestinal epithelial cells through histone acetylation. Mol Med vol. 5, (9) 631-640.
10.1007/bf03402075
Kelly EJ, Sanderson IR(1999). Nutrient regulation of intestinal gene expression. Curr Opin Clin Nutr Metab Care vol. 2, (4) 303-306.
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Sanderson IR(1999). The physicochemical environment of the neonatal intestine. Am J Clin Nutr vol. 69, (5) 1028S-1034S.
10.1093/ajcn/69.5.1028s
Siafakas CG, Anatolitou F, Fusunyan RD, Walker WA, Sanderson IR(1999). Vascular endothelial growth factor (VEGF) is present in human breast milk and its receptor is present on intestinal epithelial cells. Pediatr Res vol. 45, (5 Pt 1) 652-657.
10.1203/00006450-199905010-00007
Keshavarzian A, Fusunyan RD, Jacyno M, Winship D, MacDermott RP, Sanderson IR(1999). Increased interleukin-8 (IL-8) in rectal dialysate from patients with ulcerative colitis: evidence for a biological role for IL-8 in inflammation of the colon. Am J Gastroenterol vol. 94, (3) 704-712.
10.1111/j.1572-0241.1999.00940.x
Savage MO, Beattie RM, Camacho-Hübner C, Walker-Smith JA, Sanderson IR(1999). Growth in Crohn's disease. Acta Paediatr Suppl vol. 88, (428) 89-92.
Sanderson IR (1999). Nutrition and gene expression. INFLAMMATORY BOWEL DISEASES. Editors: Bistrian, BR, WalkerSmith, JA, vol. 2, 121-137.
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Sanderson IR(1998). Dietary regulation of genes expressed in the developing intestinal epithelium. Am J Clin Nutr vol. 68, (5) 999-1005.
10.1093/ajcn/68.5.999
Lim S, Dohil R, Meadows N, Domizio P, Sanderson IR(1998). Treatment of orofacial and ileo-colonic Crohn's disease with total enteral nutrition. J R Soc Med vol. 91, (9) 489-490.
10.1177/014107689809100909
Nishimura A, Fujimoto M, Oguchi S, Fusunyan RD, MacDermott RP, Sanderson IR(1998). Short-chain fatty acids regulate IGF-binding protein secretion by intestinal epithelial cells. Am J Physiol vol. 275, (1) E55-E63.
10.1152/ajpendo.1998.275.1.E55
Fusunyan RD, Quinn JJ, Ohno Y, MacDermott RP, Sanderson IR(1998). Butyrate enhances interleukin (IL)-8 secretion by intestinal epithelial cells in response to IL-1beta and lipopolysaccharide. Pediatr Res vol. 43, (1) 84-90.
10.1203/00006450-199804001-00501
Sanderson IR(1997). Forkheads, winged helices, and gastrointestinal epithelium. Gut vol. 41, (6) 853-854.
10.1136/gut.41.6.853
Ohno Y, Lee J, Fusunyan RD, MacDermott RP, Sanderson IR(1997). Macrophage inflammatory protein-2: chromosomal regulation in rat small intestinal epithelial cells. Proc Natl Acad Sci U S A vol. 94, (19) 10279-10284.
10.1073/pnas.94.19.10279
Sanderson IR(1997). Diet and gene expression in the intestine. Baillieres Clin Gastroenterol vol. 11, (3) 441-463.
10.1016/S0950-3528(97)90026-9
Oguchi S, Shinohara K, Yamashiro Y, Walker WA, Sanderson IR(1997). Growth factors in breast milk and their effect on gastrointestinal development. Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi vol. 38, (5) 332-337.
Sanderson IR, Ezzell RM, Kedinger M, Erlanger M, Xu ZX, Pringault E, Leon-Robine S, Louvard D et al.(1996). Human fetal enterocytes in vitro: modulation of the phenotype by extracellular matrix. Proc Natl Acad Sci U S A vol. 93, (15) 7717-7722.
10.1073/pnas.93.15.7717
Sanderson IR, Xu Z, Chu SW, Xie QY, Levine LJ, Walker WA(1996). Developmental differences in the expression of the cholera toxin sensitive subunit (Gs alpha) of adenylate cyclase in the rat small intestine. Gut vol. 38, (6) 853-858.
10.1136/gut.38.6.853
Insoft RM, Sanderson IR, Walker WA(1996). Development of immune function in the intestine and its role in neonatal diseases. Pediatr Clin North Am vol. 43, (2) 551-571.
10.1016/S0031-3955(05)70420-X
Tanaka M, Lee K, Martinez-Augustin O, He Y, Sanderson IR, Walker WA(1996). Exogenous nucleotides alter the proliferation, differentiation and apoptosis of human small intestinal epithelium. J Nutr vol. 126, (2) 424-433.
10.1093/jn/126.2.424
Sanderson IR, Walker WA(1995). Establishment of a human fetal small intestinal epithelial cell line. Int Arch Allergy Immunol vol. 107, (1-3) 396-397.
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Oguchi S, Walker WA, Sanderson IR(1995). Differentiation and polarity alter the binding of IGF-I to human intestinal epithelial (Caco-2) cells. J Pediatr Gastroenterol Nutr vol. 20, (2) 148-155.
10.1097/00005176-199502000-00003
Oguchi S, Walker WA, Sanderson IR(1995). Iron saturation alters the effect of lactoferrin on the proliferation and differentiation of human enterocytes (Caco-2 cells). Biol Neonate vol. 67, (5) 330-339.
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Sanderson IR(1994). New approaches to the study of human pediatric disease. Acta Paediatr Jpn vol. 36, (5) 572-578.
He Y, Sanderson IR, Walker WA(1994). Uptake, transport and metabolism of exogenous nucleosides in intestinal epithelial cell cultures. J Nutr vol. 124, (10) 1942-1949.
10.1093/jn/124.10.1942
Sanderson IR(1994). Unusual colitides. Baillieres Clin Gastroenterol vol. 8, (1) 181-196.
10.1016/S0950-3528(06)80025-4
Sanderson IR, He Y(1994). Nucleotide uptake and metabolism by intestinal epithelial cells. J Nutr vol. 124, (1 Suppl) 131S-137S.
10.1093/jn/124.suppl_1.131S
Oguchi S, Walker WA, Sanderson IR(1993). Insulin-like growth factor binding protein profile secreted by human intestinal epithelial cells varies with polarity. Biochem Biophys Res Commun vol. 196, (2) 789-793.
10.1006/bbrc.1993.2318
Sanderson IR, Ouellette AJ, Carter EA, Harmatz PR(1993). Ontogeny of Ia messenger RNA in the mouse small intestinal epithelium is modulated by age of weaning and diet. Gastroenterology vol. 105, (4) 974-980.
10.1016/0016-5085(93)90939-A
Sanderson IR, Ouellette AJ, Carter EA, Walker WA, Harmatz PR(1993). Differential regulation of B7 mRNA in enterocytes and lymphoid cells. Immunology vol. 79, (3) 434-438.
Hanson DG, Roy MJ, Miller SD, Seidman EG, Thomas MJ, Sanderson IR, Udall JN, Ely I et al.(1993). Endopeptidase inhibition and intestinal antigen processing in mice. Reg Immunol vol. 5, (2) 85-93.
Sanderson IR, Walker WA(1993). Uptake and transport of macromolecules by the intestine: possible role in clinical disorders (an update). Gastroenterology vol. 104, (2) 622-639.
10.1016/0016-5085(93)90436-G
Sanderson IR, Ouellette AJ, Carter EA, Harmatz PR(1992). Ontogeny of class II MHC mRNA in the mouse small intestinal epithelium. Mol Immunol vol. 29, (10) 1257-1263.
10.1016/0161-5890(92)90062-3
Walker WA, Sanderson IR(1992). Epithelial barrier function to antigens. An overview. Ann N Y Acad Sci vol. 664, 10-17.
10.1111/j.1749-6632.1992.tb39744.x
Sanderson IR, Phillips AD, Spencer J, Walker-Smith JA(1991). Response to autoimmune enteropathy to cyclosporin A therapy. Gut vol. 32, (11) 1421-1425.
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Sanderson IR, Risdon RA, Walker-Smith JA(1991). Intractable ulcerating enterocolitis of infancy. Arch Dis Child vol. 66, (3) 295-299.
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Sanderson IR, Bisset WM, Milla PJ, Leonard JV(1991). Chronic inflammatory bowel disease in glycogen storage disease type 1B. J Inherit Metab Dis vol. 14, (5) 771-776.
10.1007/BF01799948
Sanderson IR, Pritchard J, Marsh HT(1989). Chemotherapy as the initial treatment of spinal cord compression due to disseminated neuroblastoma. J Neurosurg vol. 70, (5) 688-690.
10.3171/jns.1989.70.5.0688
Brueton LA, Sanderson IR, Jadresic L, Harper JI, Savage MO, Ansell BM(1989). An infant with chronic articular and cutaneous manifestations: a new syndrome?. J R Soc Med vol. 82, (4) 223-225.
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Sanderson IR, Carter EP, Dillon MJ, Oberholzer VG, Savage MO(1989). Familial salivary gland insensitivity to aldosterone: a variant of pseudohypoaldosteronism. Horm Res vol. 32, (4) 145-147.
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Hill SM, Phillips AD, Walker-Smith JA, Sanderson IR, Milla PJ(1988). Antibiotics for Escherichia coli gastroenteritis. Lancet vol. 1, (8588) 771-772.
10.1016/S0140-6736(88)91584-X
Sanderson IR, Boulton P, Menzies I, Walker-Smith JA(1987). Improvement of abnormal lactulose/rhamnose permeability in active Crohn's disease of the small bowel by an elemental diet. Gut vol. 28, (9) 1073-1076.
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Sanderson IR, Brueton LA, Savage MO, Harper JI(1987). Eczema herpeticum: a potentially fatal disease. Br Med J (Clin Res Ed) vol. 294, (6573) 693-694.
Sanderson IR, Udeen S, Davies PS, Savage MO, Walker-Smith JA(1987). Remission induced by an elemental diet in small bowel Crohn's disease. Arch Dis Child vol. 62, (2) 123-127.
10.1136/adc.62.2.123
Sanderson IR, Boyle S, Williams CB, Walker-Smith JA(1986). Histological abnormalities in biopsies from macroscopically normal colonoscopies. Arch Dis Child vol. 61, (3) 274-277.
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Dourmashkin RR, Sanderson I, Walker-Smith JA, Dalgleish AG(1986). Is Crohn's disease caused by a lymphotropic virus?. J Pediatr Gastroenterol Nutr vol. 5, (2)
Sanderson IR, Leung KB, Pearce FL, Walker-Smith JA(1986). Lamina propria mast cells in biopsies from children with Crohn's disease. J Clin Pathol vol. 39, (3) 279-283.
10.1136/jcp.39.3.279
Sanderson IR(1986). Chronic inflammatory bowel disease. Clin Gastroenterol vol. 15, (1) 71-87.
Sanderson IR, Kingston JE, Khan S, Walker-Smith JA(1985). Hodgkin's disease complicating Crohn's disease in a child. J R Soc Med vol. 78, (10) 860-861.
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Sanderson IR, Walker-Smith JA(1985). Crohn's disease in childhood. Br J Surg vol. 72 Suppl, S87-S90.
10.1002/bjs.1800721345
Sanderson IR, Slavin G, Walker-Smith JA(1985). Density of mucosal mast cells in the lamina propria of the colon and terminal ileum of children. J Clin Pathol vol. 38, (7) 771-773.
10.1136/jcp.38.7.771
Sanderson IR, Walker-Smith JA(1984). Indigenous amoebiasis: an important differential diagnosis of chronic inflammatory bowel disease. Br Med J (Clin Res Ed) vol. 289, (6448)
Chong SK, Sanderson IR, Wright V, Walker-Smith JA(1984). Food allergy and infantile colitis. Arch Dis Child vol. 59, (7) 690-691.
10.1136/adc.59.7.690
Sanderson IR(1982). Headache and tumours in children. Br Med J (Clin Res Ed) vol. 285, (6340)
Parsons DS, Sanderson IR(1980). Influence of vascular flow on amino acid transport across frog small intestine. J Physiol vol. 309, 447-460.
10.1113/jphysiol.1980.sp013519
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