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Publications:  Prof Rupert Pearse

Duceppe E, Patel A, Chan MTV, Berwanger O, Ackland G, Kavsak PA, Rodseth R, Biccard B et al.(2020). Preoperative n-terminal pro-b-type natriuretic peptide and cardiovascular events after noncardiac surgery: A cohort study. Annals of Internal Medicine vol. 172, (2) 96-104.
10.7326/M19-2501
Turan A, Artis AS, Hanline C, Saha P, Maheshwari K, Kurz A, Devereaux PJ, Duceppe E et al.(2020). Preoperative Vitamin D Concentration and Cardiac, Renal, and Infectious Morbidity after Noncardiac Surgery. Anesthesiology vol. 132, (1) 121-130.
10.1097/ALN.0000000000003000
Wijeysundera D, Beattie WS, Hillis G, ABBOTT T, Shulman M, Ackland G, Mazer D, Myles P et al.(2019). Integration of the Duke Activity Status Index into Preoperative Risk Evaluation: A Multicentre Prospective Cohort Study. British Journal of Anaesthesia
10.1016/j.bja.2019.11.025
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62126
Scheeren TWL, Bakker J, De Backer D, Annane D, Asfar P, Boerma EC, Cecconi M, Dubin A et al.(2019). Current use of vasopressors in septic shock. Annals of Intensive Care vol. 9, (1)
10.1186/s13613-019-0498-7
Yang F, Walker S, Richardson G, Stephens T, Phull M, Thompson A, Pearse RM(2019). Reply letter to: “A commentary on “cost-effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery, health economic evaluation” (int J Surg 2019; epub ahead of print)”. International Journal of Surgery vol. 72, 252-253.
10.1016/j.ijsu.2019.11.020
Macdonald N, Pearse RM, Murray PT, Inzitari R, Doran P, Prowle JR(2019). The role of goal-directed therapy in the prevention of acute kidney injury after major gastrointestinal surgery: Substudy of the OPTIMISE trial. European Journal of Anaesthesiology vol. 36, (12) 924-932.
10.1097/EJA.0000000000001104
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61126
Yang F, Walker S, Richardson G, Stephens T, Phull M, Thompson A, Pearse RM, Enhanced Peri-Operative Care for High-risk patients (EPOCH) trial group(2019). Cost-effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery: Learning from 15,856 patients. International Journal of Surgery vol. 72, 25-31.
10.1016/j.ijsu.2019.10.001
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62739
Murray D, Pearse RM, Quiney N(2019). Towards a coordinated national strategy to improve survival after emergency laparotomy. Br J Anaesth vol. 123, (4) 399-401.
10.1016/j.bja.2019.06.023
Cashmore R, Fowler A, Pearse R(2019). Post-operative intensive care: is it really necessary?. Intensive Care Medicine
10.1007/s00134-019-05775-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62005
Haines R, Zolfaghari P, Wan Y, PUTHUCHEARY Z, Pearse R, Prowle J(2019). Elevated urea to creatinine ratio provides a biochemical signature of muscle catabolism and persistent critical illness after major trauma. Intensive Care Medicine
10.1007/s00134-019-05760-5
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59545
Stephens TJ, Peden CJ, Haines R, Grocott MPW, Murray D, Cromwell D, Johnston C, Hare S et al.(2019). Hospital-level evaluation of the effect of a national quality improvement programme: time-series analysis of registry data. BMJ Quality and Safety
10.1136/bmjqs-2019-009537
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61464
Stephens T, Pearse RM(2019). Learning from the EPOCH trial (Editorial). What we have learnt from a trial of an intervention to improve survival following emergency laparotomy. Anaesthesia Critical Care and Pain Medicine vol. 38, (4) 321-322.
10.1016/j.accpm.2019.06.006
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58970
The Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators(2019). Association between complications and death within 30 days after noncardiac surgery. Canadian Medical Association Journal vol. 191, (30) E830-E837.
10.1503/cmaj.190221
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60052
Peden CJ, Stephens T, Martin G, Kahan BC, Thomson A, Rivett K, Wells D, Richardson G et al.(2019). Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial. The Lancet vol. 393, (10187) 2213-2221.
10.1016/S0140-6736(18)32521-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54603
Fowler AJ, ABBOTT T, PROWLE J, PEARSE R(2019). Age of patients undergoing surgery. British Journal of Surgery
10.1002/bjs.11148
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58766
Haller G, Bampoe S, Cook T, Fleisher LA, Grocott MPW, Neuman M, Story D, Myles PS et al.(2019). Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators. British Journal of Anaesthesia
10.1016/j.bja.2019.04.041
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59546
ABBOTT TEF, PEARSE RM, beattie S, Phull M, Beilstein C, Raj A, Grocott M, Cuthbertson B et al.(2019). Chronotropic incompetence and myocardial injury after non-cardiac surgery: planned secondary analysis of a prospective observational international cohort study. BJA: British Journal of Anaesthesia vol. 123, (1) 17-26.
10.1016/j.bja.2019.03.022
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56417
Bishop D, Dyer RA, Maswime S, Rodseth RN, van Dyk D, Kluyts HL, Tumukunde JT, Madzimbamuto FD et al.(2019). Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study: a 7-day prospective observational cohort study. The Lancet Global Health vol. 7, (4) e513-e522.
10.1016/S2214-109X(19)30036-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58691
Edwards MR, Forbes G, MacDonald N, Berdunov V, Mihaylova B, Dias P, Thomson A, Grocott MP et al.(2019). Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery. BMJ Open vol. 9, (1) e023455-e023455.
10.1136/bmjopen-2018-023455
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56225
ABBOTT TEF, PEARSE R(2019). Depth of Anesthesia and Postoperative Delirium. JAMA - Journal of the American Medical Association vol. 321, (5) 459-460.
10.1001/jama.2019.0164
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55562
ABBOTT TEF, Greaves K, PEARSE RM, Writing committee for the International Surgical Outcomes Study (ISOS) group(2019). Prospective observational cohort study on grading the severity of postoperative complications in global surgery research. British Journal of Surgery vol. 106, e73-e80.
10.1002/bjs.11025
https://qmro.qmul.ac.uk/xmlui/handle/123456789/53289
Abbott TEF, Pearse RM, Cuthbertson BH, Wijeysundera DN, Ackland GL(2019). Cardiac vagal dysfunction and myocardial injury after non-cardiac surgery: a planned secondary analysis of the measurement of Exercise Tolerance before surgery study. British Journal of Anaesthesia
10.1016/j.bja.2018.10.060
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57537
Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA et al.(2019). Correction: Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies (PLoS ONE (2019) 14:8 (e0221277) DOI: 10.1371/journal.pone.0221277). PLoS ONE vol. 14, (12)
10.1371/journal.pone.0226379
Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA et al.(2019). Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies. PLoS ONE vol. 14, (8)
10.1371/journal.pone.0221277
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61876
Barnes J, Hunter J, Harris S, Shankar-Hari M, Diouf E, Jammer I, Kalkman C, Klein AA et al.(2019). Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis. British Journal of Anaesthesia
10.1016/j.bja.2019.01.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59006
Shulman MA, Cuthbertson BH, Wijeysundera DN, Pearse RM, Thompson B, Torres E, Ambosta A, Wallace S et al.(2019). Using the 6-minute walk test to predict disability-free survival after major surgery. British Journal of Anaesthesia vol. 122, (1) 111-119.
10.1016/j.bja.2018.08.016
Kluyts HL, le Manach Y, Munlemvo DM, Madzimbamuto F, Basenero A, Coulibaly Y, Rakotoarison S, Gobin V et al.(2018). The ASOS Surgical Risk Calculator: development and validation of a tool for identifying African surgical patients at risk of severe postoperative complications. British Journal of Anaesthesia vol. 121, (6) 1357-1363.
10.1016/j.bja.2018.08.005
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56730
Stephens TJ, Peden CJ, Pearse RM, Shaw SE, Abbott TEF, Jones E, Kocman D, Martin G et al.(2018). Improving care at scale: Process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial). Implementation Science vol. 13, (1)
10.1186/s13012-018-0823-9
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54101
Chaudery H, MacDonald N, Ahmad T, Chandra S, Tantri A, Sivasakthi V, Mansor M, Matos R et al.(2018). Acute Kidney Injury and Risk of Death After Elective Surgery: Prospective Analysis of Data From an International Cohort Study. Anesth Analg
10.1213/ANE.0000000000003923
https://qmro.qmul.ac.uk/xmlui/handle/123456789/51644
Fowler AJ, AHMAD T, ABBOTT T, TORRANCE H, PEARSE R, Wouters PF, De Hert S, Lobo SM et al.(2018). Association of preoperative anaemia with postoperative morbidity and mortality: an observational cohort study in low-, middle-, and high-income countries. British Journal of Anaesthesia vol. 121, (6) 1227-1235.
10.1016/j.bja.2018.08.026
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49263
Bloom B, Thomas S, Ahrensberg JM, Weaver R, Fowler A, Bestwick J, Harris T, Pearse R(2018). A systematic review and meta-analysis of return to work after mild Traumatic brain injury. Brain Inj1-14.
10.1080/02699052.2018.1532111
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49183
Ackland GL, Abbott TEF, Cain D, Edwards MR, Sultan P, Karmali SN, Fowler AJ, Whittle JR et al.(2019). Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery. British Journal of Anaesthesia
10.1016/j.bja.2018.09.002
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49203
TORRANCE H, LONGBOTTOM R, VIVIAN M, Lalabekyan B, ABBOTT TEF, ACKLAND GL, HINDS CJ, PEARSE RM et al.(2018). Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery. PLoS ONE vol. 13, (9)
10.1371/journal.pone.0203795
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45023
Hewitt Smith A, Bulamba F, Olupot C, Musana F, Ochieng JP, Lipnick MS, Pearse RM(2018). Surgical outcomes in eastern Uganda: A one-year cohort study. Southern African Journal of Anaesthesia and Analgesia vol. 24, (5) 122-127.
10.1080/22201181.2018.1517476
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58692
Greenberg L, Jairath V, Pearse R, Kahan BC(2018). Prespecification of statistical analysis approaches in published clinical trial protocols was inadequate. Journal of Clinical Epidemiology vol. 101, 53-60.
10.1016/j.jclinepi.2018.05.023
Pearse RM, Hopkins PM(2018). Where audit meets science: role of reporting and recommendations guidelines in service evaluations. Br J Anaesth vol. 121, (1) 118-120.
10.1016/j.bja.2018.05.007
Wijeysundera D, PEARSE R, shulman M, ABBOTT TEF, Torres E, Ambosta A, Bernard C, Granton J et al.(2018). Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study. Lancet vol. 391, (10140) 2631-2640.
10.1016/S0140-6736(18)31131-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42364
WALKER S, ABBOTT TEF, Brown K, PEARSE R, ACKLAND G(2018). Perioperative management of angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers: a survey of perioperative medicine practitioners. PeerJ
10.7717/peerj.5061
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42127
Lurati Buse G, Manns B, Lamy A, Guyatt G, Polanczyk CA, Chan MTV, Wang CY, Villar JC et al.(2018). Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost–consequence analysis. Canadian Journal of Surgery vol. 61, (3) 185-194.
10.1503/cjs.010217
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39863
Kahan BC, Morris TP, Harris E, Pearse R, Hooper R, Eldridge S(2018). Re-randomization increased recruitment and provided similar treatment estimates as parallel designs in trials of febrile neutropenia. Journal of Clinical Epidemiology vol. 97, 14-19.
10.1016/j.jclinepi.2018.02.002
https://qmro.qmul.ac.uk/xmlui/handle/123456789/40443
ABBOTT TEF, Fowler A, Pelosi P, Garna de Abru M, Moller A, Canet J, Creagh-Brown B, Mythen M et al.(2018). A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications. British Journal of Anaesthesia
10.1016/j.bja.2018.02.007
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38183
Yeung J, Gillies MA, Pearse RM(2018). Pragmatic trials in peri-operative medicine: why, when and how?. Anaesthesia
10.1111/anae.14252
PROWLE JR(2018). Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model. Scientific Reports
10.1038/s41598-018-21929-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34319
PEARSE RM(2018). Perioperative patient outcomes in the African Surgical Outcomes Study: a 7-day prospective observational cohort study. Lancet
10.1016/S0140-6736(18)30001-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/51443
ackland GL, ABBOTT T, Pearse RM, Karmali S, Whittle J, Minto G(2018). Arterial pulse pressure and postoperative morbidity in high-risk surgical patients. British Journal of Anaesthesia vol. 120, (1) 94-100.
10.1016/j.bja.2017.11.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24953
ABBOTT T, Ahmad T, Phull M, Fowler A, Hewson R, Biccard B, Chew M, Gillies M et al.(2018). The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis. British Journal of Anaesthesia vol. 120, (1) 146-155.
10.1016/j.bja.2017.08.002
https://qmro.qmul.ac.uk/xmlui/handle/123456789/31564
MacDonald N, Pearse RM(2017). Are we close to the ideal intravenous fluid?. Br J Anaesth vol. 119, (suppl_1) i63-i71.
10.1093/bja/aex293
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42485
Moppett IK, Pearse RM(2017). Evidence-based medicine: the clue is in the name. Br J Anaesth vol. 119, (6) 1084-1086.
10.1093/bja/aex337
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32243
ABBOTT T, pearse RM, Archbold RA, Ahmad T, Niebrzegowska E, Wragg A, Rodseth R, Devereaux PJ et al.(2018). A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study. Anesthesia and Analgesia vol. 126, (6) 1936-1945.
10.1213/ANE.0000000000002560
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36643
Vellinga NAR, Boerma EC, Koopmans M, Donati A, Dubin A, Shapiro NI, Pearse RM, van der Voort PHJ et al.(2017). Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: A microSOAP post hoc analysis. Critical Care vol. 21, (1)
10.1186/s13054-017-1842-7
Gillies MA, Sander M, Shaw A, Wijeysundera DN, Myburgh J, Aldecoa C, Jammer I, Lobo SM et al.(2017). Current research priorities in perioperative intensive care medicine. Intensive Care Med vol. 43, (9) 1173-1186.
10.1007/s00134-017-4848-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24806
Szakmany T, Ditai J, Kirov M, Protsenko D, Osinaike B, Venara A, Demartines N, Hubner M et al.(2017). In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study. EJSO - European Journal of Surgical Oncology
10.1016/j.ejso.2017.08.002
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25370
Schultz MJ, Hemmes SNT, Neto AS, Binnekade JM, Canet J, Hedenstierna G, Jaber S, Hiesmayr M et al.(2017). Epidemiology, practice of ventilation and outcome for patients at increased risk of postoperative pulmonary complications: LAS VEGAS - An observational study in 29 countries. European Journal of Anaesthesiology vol. 34, (8) 492-507.
10.1097/EJA.0000000000000646
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36609
Chaudery H, MacDonald N, Pearse RM, Prowle JR (2017). Global Incidence and Associations of Acute Kidney Injury in the International Surgical Outcomes Study (ISOS). vol. 119, is. 2, pp. E28-E28.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32224
Ahmad T, Bouwman RA, Grigoras I, Aldecoa C, Hofer C, Hoeft A, Holt P, Fleisher LA et al.(2017). Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: A 7-day cohort study of elective surgery. British Journal of Anaesthesia vol. 119, (2) 258-266.
10.1093/bja/aex185
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25107
ABBOTT T, Pearse R, Dobbs TD, Harrison EM, Gillies MA, Fowler AJ(2017). Frequency of surgical treatment and related hospital procedures in the United Kingdom: A national ecological study using hospital episode statistics. British Journal Of Anaesthesia vol. 119, (2) 249-257.
10.1093/bja/aex137
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25383
ABBOTT T, pearse R, ahmad T, ackland G(2017). Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery. British Journal Of Anaesthesia vol. 119, (1) 78-86.
10.1093/bja/aex165
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25477
ABBOTT T, Lee A, Pearse R, Ackland G, Minto G(2017). Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients. British Journal Of Anaesthesia vol. 119, (1) 87-94.
10.1093/bja/aex164
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25476
Martin GP, Kocman D, Stephens T, Peden CJ, Pearse RM, This study was carried out as part of a wider randomised controlled trial, EPOCH(2017). Pathways to professionalism? Quality improvement, care pathways, and the interplay of standardisation and clinical autonomy. Sociol Health Illn
10.1111/1467-9566.12585
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25204
ABBOTT T, Pearse RM(2017). Saving money: an ideal driver for improved perioperative care?. Anaesth Crit Care Pain Med vol. 36, (3) 147-148.
10.1016/j.accpm.2017.01.006
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19367
Writing Committee for the VISION Study Investigators, Devereaux PJ, Biccard BM, Sigamani A, Xavier D, Chan MTV, Srinathan SK, Walsh M et al.(2017). Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery. JAMA vol. 317, (16) 1642-1651.
10.1001/jama.2017.4360
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58626
Kahan BC, Koulenti D, Arvaniti K, Beavis V, Campbell D, Chan M, Moreno R, Pearse RM et al.(2017). Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries. Intensive Care Med vol. 43, (7) 971-979.
10.1007/s00134-016-4633-8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23062
O'Connor ME, Hewson RW, Kirwan CJ, Ackland GL, Pearse RM, Prowle JR(2017). Acute kidney injury and mortality 1 year after major non-cardiac surgery. British Journal of Surgery
10.1002/bjs.10498
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19798
Pearse RM, ABBOTT T, Haslop R, Ahmad T, Kahan BC, Filippini C, Rhodes A, Ranieri M(2017). Prevention of Respiratory Insufficiency after Surgical Management (PRISM) trial: report of the protocol for a pragmatic randomised controlled trial of Continuous Positive Airway Pressure (CPAP) to prevent respiratory complications and improve survival following major abdominal surgery. Minerva Anestesiol vol. 83, (2) 175-182.
10.23736/S0375-9393.16.11502-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19079
Bloom BM, Kinsella K, Pott J, Patel HC, Harris T, Lecky F, Pearse R(2017). Short-term neurocognitive and symptomatic outcomes following mild traumatic brain injury: A prospective multi-centre observational cohort study. Brain Inj vol. 31, (3) 304-311.
10.1080/02699052.2016.1256501
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19566
Davenport RA, Guerreiro M, Frith D, Rourke C, Platton S, Cohen M, Pearse R, Thiemermann C et al.(2017). Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy. Anesthesiology vol. 126, (1) 115-127.
10.1097/ALN.0000000000001428
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17825
Gillies MA, Harrison EM, Pearse RM, Garrioch S, Haddow C, Smyth L, Parks R, Walsh TS et al.(2017). Intensive care utilization and outcomes after high-risk surgery in Scotland: a population-based cohort study. Br J Anaesth vol. 118, (1) 123-131.
10.1093/bja/aew396
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18739
Pearse R(2016). Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries. British Journal of Anaesthesia vol. 117, (5) 601-609.
10.1093/bja/aew316
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17816
Prowle JR, Kam EPY, Ahmad T, Smith NCE, Protopapa K, Pearse RM(2016). Preoperative renal dysfunction and mortality after non-cardiac surgery. The British journal of surgery vol. 103, (10) 1316-1325.
10.1002/bjs.10186
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13833
Longbottom ER, Torrance HDT, Owen HC, Fragkou PC, Hinds CJ, Pearse RM, O'Dwyer MJ(2016). Features of Postoperative Immune Suppression Are Reversible with Interferon Gamma and Independent of Interleukin-6 Pathways. Annals of Surgery vol. 264, (2) 370-377.
10.1097/SLA.0000000000001484
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11890
Abbott TEF, Ackland GL, Archbold RA, Wragg A, Kam E, Ahmad T, Khan AW, Niebrzegowska E et al.(2016). Preoperative heart rate and myocardial injury after non-cardiac surgery: results of a predefined secondary analysis of the VISION study. British Journal of Anaesthesia vol. 117, (2) 172-181.
10.1093/bja/aew182
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13922
Torrance HDT, Pearse RM, O'Dwyer MJ(2016). Does major surgery induce immune suppression and increase the risk of postoperative infection?. Curr Opin Anaesthesiol vol. 29, (3) 376-383.
10.1097/ACO.0000000000000331
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24596
Bloom BM, Maimaris C, Lecky F, Pearse R(2016). Letter in Response to 'Classification of Traumatic Brain Injury Severity Using Informed Data Reduction in a Series of Binary Classifier Algorithms'. IEEE Transactions on Neural Systems and Rehabilitation Engineering vol. 24, (5)
10.1109/TNSRE.2015.2479412
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19565
O'Connor ME, Kirwan CJ, Pearse RM, Prowle JR(2016). Incidence and associations of acute kidney injury after major abdominal surgery. Intensive care medicine vol. 42, (4) 521-530.
10.1007/s00134-015-4157-7
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10969
Gillies MA, Pearse RM(2016). Intensive Care after High-risk Surgery: What's in a Name?. Anesthesiology vol. 124, (4) 761-762.
10.1097/aln.0000000000001025
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11475
Wijeysundera DN, Pearse RM, Shulman MA, Abbott TEF, Torres E, Croal BL, Granton JT, Thorpe KE et al.(2016). Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery. BMJ Open vol. 6, (3) e010359-e010359.
10.1136/bmjopen-2015-010359
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12155
Ozdemir BA, Sinha S, Karthikesalingam A, Poloniecki JD, Pearse RM, Grocott MPW, Thompson MM, Holt PJE(2016). Mortality of emergency general surgical patients and associations with hospital structures and processes. Br J Anaesth vol. 116, (1) 54-62.
10.1093/bja/aev372
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11488
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Prowle JR, Kolic I, Purdell-Lewis J, Taylor R, Pearse RM, Kirwan CJ(2014). Serum creatinine changes associated with critical illness and detection of persistent renal dysfunction after AKI. Clin J Am Soc Nephrol vol. 9, (6) 1015-1023.
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James S, Jhanji S, Smith A, O'Brien G, Fitzgibbon M, Pearse RM(2014). Comparison of the prognostic accuracy of scoring systems, cardiopulmonary exercise testing, and plasma biomarkers: a single-centre observational pilot study. Br J Anaesth vol. 112, (3) 491-497.
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Dreyer G, Tucker AT, Harwood SM, Pearse RM, Raftery MJ, Yaqoob MM(2014). Ergocalciferol and microcirculatory function in chronic kidney disease and concomitant vitamin d deficiency: an exploratory, double blind, randomised controlled trial. PLoS One vol. 9, (7)
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Gillies MA, Habicher M, Jhanji S, Sander M, Mythen M, Hamilton M, Pearse RM(2014). Incidence of postoperative death and acute kidney injury associated with i.v. 6 hydroxyethyl starch use: systematic review and meta-analysis. BRITISH JOURNAL OF ANAESTHESIA vol. 112, (1) 25-34.
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Baron DM, Hochrieser H, Metnitz B, Rhodes A, Moreno RP, Pearse RM, Metnitz P, Investigators E (2013). PREOPERATIVE ANEMIA AND POLYCYTHEMIA ARE ASSOCIATED WITH A HIGHER IN-HOSPITAL MORTALITY IN NON-CARDIAC SURGERY PATIENTS. INTENSIVE CARE MEDICINE. vol. 39, S285-S285.
Cecconi M, Hochrieser H, Metnitz B, Moreno R, Pearse R, Metnitz P, Rhodes A, Investigators E (2013). PREOPERATVE SERUM SODIUM AND POSTOPERATIVE MORTALITY: A EUSOS SUBSTUDY. INTENSIVE CARE MEDICINE. vol. 39, S337-S338.
Pearse RM, van Zaane B, Moreno RP, Buhre WF, van Klei WA, Rhodes A, Med ESIC, Anaesthesiology ES (2013). START TIMES OF EMERGENCY SURGERY AND IN HOSPITAL MORTALITY: A COHORT STUDY ON THE EUSOS DATABASE COMPARING MORTALITY AFTER DAY SHIFT, EVENING SHIFT AND NIGHT SHIFT PROCTDURES. INTENSIVE CARE MEDICINE. vol. 39, S349-S349.
Diogo AC, Iannuccelli F, Rhodes A, Pearse R, Moreno R (2013). THE RELATIONSHIP BETWEEN THE ASA SCORE AND OUTCOME FROM SURGERY. RESULTS FROM THE EUSOS STUDY. INTENSIVE CARE MEDICINE. vol. 39, S349-S349.
Reynolds T, Vivian-Smith A, Jhanji S, Pearse RM(2013). Observational study of the effects of age, diabetes mellitus, cirrhosis and chronic kidney disease on sublingual microvascular flow. Perioper Med (Lond) vol. 2, (1)
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Bangash MN, Patel NSA, Benetti E, Collino M, Hinds CJ, Thiemermann C, Pearse RM(2013). Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. Crit Care vol. 17, (2)
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Prowle JR, Pearse RM(2013). Is it the end of the road for synthetic starches in critical illness?. BMJ (Online) vol. 346, (7900)
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Grocott MPW, Pearse RM(2012). Perioperative medicine: the future of anaesthesia?. BRITISH JOURNAL OF ANAESTHESIA vol. 108, (5) 723-726.
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Pearse RM, Ackland GL(2012). Perioperative fluid therapy. BMJ vol. 344,
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Bangash MN, Kong M-L, Pearse RM(2012). Use of inotropes and vasopressor agents in critically ill patients. Br J Pharmacol vol. 165, (7) 2015-2033.
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Terblanche M, Kruger P, di Gangi S, Gearay S, Gilfeather L, Ferguson ND, Pearse R, Beale R et al.(2012). Risk factors for acute organ failure in intensive care unit patients who receive respiratory support in the absence of non-respiratory organ failure: an international prospective cohort study. CRITICAL CARE vol. 16, (2) Article ARTN R61,
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James S, Jhanji S, Niebrzegowska E, Tarrell T, Smith AV, Pearse R (2011). PERI-OPERATIVE MICROVASCULAR FLOW AND CARDIO-PULMONARY EXERCISE TESTLNG IN HIGH RISK SURGICAL PATIENTS. INTENSIVE CARE MEDICINE. vol. 37, S132-S132.
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Martin-Loeches I, Lisboa T, Rhodes A, Moreno RP, Silva E, Sprung C, Chiche JD, Barahona D et al.(2011). Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection. Intensive Care Medicine vol. 37, (2) 272-283.
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Rampal T, Jhanji S, Pearse RM(2010). Using oxygen delivery targets to optimize resuscitation in critically ill patients. Curr Opin Crit Care vol. 16, (3) 244-249.
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Pearse RM(2010). Water, taken in moderation, cannot hurt anybody (Mark Twain 1835-1910). J PHYSIOL-LONDON vol. 588, (2) 281-282.
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Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds CJ, Pearse RM(2010). Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial. Crit Care vol. 14, (4)
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Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds CJ, Pearse RM (2009). A RANDOMISED CONTROLLED TRIAL OF THE EFFECTS OF POST-OPERATIVE HAEMODYNAMIC OPTIMISATION ON MICROVASCULAR FLOW, TISSUE OXYGENATION AND INFLAMMATORY MARKERS AFTER MAJOR ABDOMINAL SURGERY. INTENSIVE CARE MEDICINE. vol. 35, 213-213.
Shepherd SJ, Pearse RM(2009). Role of Central and Mixed Venous Oxygen Saturation Measurement in Perioperative Care. ANESTHESIOLOGY vol. 111, (3) 649-656.
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Jhanji S, Pearse RM(2009). The use of early intervention to prevent postoperative complications. Curr Opin Crit Care vol. 15, (4) 349-354.
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Jhanji S, Stirling S, Patel N, Hinds CJ, Pearse RM(2009). The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock. Crit Care Med vol. 37, (6) 1961-1966.
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Jhanji S, Lee C, Watson D, Hinds C, Pearse RM(2009). Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications. Intensive Care Med vol. 35, (4) 671-677.
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Frith D, Chesebro B, Pittet JF, Cohen MJ, Thiemermann C, Pearse R, Brohi K (2009). ACUTE TRAUMATIC COAGULOPATHY IS DRIVEN BY SYSTEMIC HYPOPERFUSION INDEPENDENT OF HYPOTENSION AND HAEMORRHAGE VOLUME. SHOCK. vol. 32, 9-9.
Maddison B, Wolff C, Findlay G, Radermacher P, Hinds C, Pearse RM(2009). Comparison of three methods of extravascular lung water volume measurement in patients after cardiac surgery. Crit Care vol. 13, (4)
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Jhanji S, Stirling S, Patel NSA, Hinds CJ, Pearse RM (2009). EFFECT OF INCREASING DOSES OF NOREPINEPHRINE ON TISSUE OXYGENATION AND MICROVASCULAR PERFUSION IN SEPTIC SHOCK. SHOCK. vol. 32, 2-2.
Pearse RM(2009). Extending the role of lactate measurement into the prehospital environment. Crit Care vol. 13, (1)
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Davenport R, Coates A, Allard S, Pasi J, MacCallum P, Stanworth S, Thiemermann C, Pearse R et al. (2009). TRAUMA HAEMORRHAGE: EVOLVING ROLE OF ROTEM FOR PREDICTING TRANSFUSION REQUIREMENTS. SHOCK. vol. 32, 15-15.
Maddison B, Giudici R, Calzia E, Wolff C, Hinds C, Radermacher P, Pearse RM(2008). Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry. Intensive Care Med vol. 34, (11) 2106-2111.
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Jhanji S, Thomas B, Ely A, Watson D, Hinds CJ, Pearse RM(2008). Mortality and utilisation of critical care resources amongst high-risk surgical patients in a large NHS trust. Anaesthesia vol. 63, (7) 695-700.
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Pearse RM, Belsey JD, Cole JN, Bennett ED(2008). Effect of dopexamine infusion on mortality following major surgery: Individual patient data meta-regression analysis of published clinical trials. CRIT CARE MED vol. 36, (4) 1323-1329.
10.1097/CCM.0b013e31816091b
Jhanji S, Dawson J, Pearse RM(2008). Cardiac output monitoring: basic science and clinical application. Anaesthesia vol. 63, (2) 172-181.
10.1111/j.1365-2044.2007.05318.x
Maddison B, Findlay G, Radermacher P, Hinds C, Pearse RM (2008). Intrathoracic blood volume measurement: A comparison of transpulmonary lithium indicator dilution with indocyanine green indicator dilution. SHOCK. vol. 29, 63-63.
Jhanji S, Lee C, Watson D, Hinds CJ, Pearse RM (2008). Tissue oxygenation and microvascular flow after major abdominal surgery. SHOCK. vol. 29, 64-64.
Frith D, Chesebro B, Patel N, Thiemermann C, Brohi K, Cohen M, Pearse R (2008). Towards a mouse model for acute coagulopathy of trauma/shock. SHOCK. vol. 29, 6-6.
Pearse RM, Young JD(2007). Steroids to prevent postextubation laryngeal oedema. Lancet vol. 369, (9567) 1060-1061.
10.1016/S0140-6736(07)60503-0
Pearse RM, Dawson D, Fawcett J, Rhodes A, Grounds RM, Bennett D(2007). The incidence of myocardial injury following post-operative Goal Directed Therapy. BMC Cardiovasc Disord vol. 7,
10.1186/1471-2261-7-10
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9990
Pearse RM, Harrison DA, James P, Watson D, Hinds C, Rhodes A, Grounds RM, Bennett ED(2006). Identification and characterisation of the high-risk surgical population in the United Kingdom. Crit Care vol. 10, (3)
10.1186/cc4928
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9888
Pearse RM, Hinds CJ(2006). Should we use central venous saturation to guide management in high-risk surgical patients?. Crit Care vol. 10, (6)
10.1186/cc5122
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11479
Wort SJ, Rhodes A, Thomas H, Pearse R, Collinson P, Bennett ED (2005). The role of plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients. THORAX. vol. 60, II116-II116.
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