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Publications:  Prof Mauro Perretti

Voisin M-B, Leoni G, Woodfin A, Loumagne L, Patel NS, Di Paola R, Cuzzocrea S, Thiemermann C et al.(2019). Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post-ischemia/reperfusion injury. J Pathol vol. 248, (1) 88-102.
10.1002/path.5234
Nadkarni S, Lashin H, Hollywood J, Dasgupta B, Mason JC, Perretti M(2019). Identification of an activated neutrophil phenotype in polymyalgia rheumatica during steroid treatment: a potential involvement of immune cell cross-talk. Clin Sci (Lond) vol. 133, (7) 839-851.
10.1042/CS20180415
Di Paola R, Fusco R, Gugliandolo E, D'Amico R, Cordaro M, Impellizzeri D, Perretti M, Cuzzocrea S(2019). Formyl peptide receptor 1 signalling promotes experimental colitis in mice. Pharmacol Res vol. 141, 591-601.
10.1016/j.phrs.2019.01.041
Sugimoto MA, Vago JP, Perretti M, Teixeira MM(2019). Mediators of the Resolution of the Inflammatory Response. Trends Immunol vol. 40, (3) 212-227.
10.1016/j.it.2019.01.007
de Gaetano M, Butler E, Gahan K, Zanetti A, Marai M, Chen J, Cacace A, Hams E et al.(2019). Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A4 mimetics (sLXms). Eur J Med Chem vol. 162, 80-108.
10.1016/j.ejmech.2018.10.049
Pessolano E, Belvedere R, Bizzarro V, Franco P, Marco ID, Porta A, Tosco A, Parente L et al.(2018). Annexin A1 May Induce Pancreatic Cancer Progression as a Key Player of Extracellular Vesicles Effects as Evidenced in the In Vitro MIA PaCa-2 Model System. Int J Mol Sci vol. 19, (12)
10.3390/ijms19123878
Thomas BL, Perretti M(2018). Neutrophil wrap. Nat Nanotechnol vol. 13, (12) 1098-1099.
10.1038/s41565-018-0260-6
Petri MH, Thul S, Andonova T, Lindquist-Liljeqvist M, Jin H, Skenteris N-T, Arnardottir H, Maegdefessel L et al.(2018). Resolution of Inflammation Through the Lipoxin and ALX/FPR2 Receptor Pathway Protects Against Abdominal Aortic Aneurysms. JACC Basic Transl Sci vol. 3, (6) 719-727.
10.1016/j.jacbts.2018.08.005
Salamah MF, Ravishankar D, Kodji X, Moraes LA, Williams HF, Vallance TM, Albadawi DA, Vaiyapuri R et al.(2018). The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Adv vol. 2, (21) 2973-2985.
10.1182/bloodadvances.2018021758
Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K et al.(2018). n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis. Brain vol. 141, (11) 3130-3143.
10.1093/brain/awy247
Hebeda CB, Machado ID, Reif-Silva I, Moreli JB, Oliani SM, Nadkarni S, Perretti M, Bevilacqua E et al.(2018). Endogenous annexin A1 (AnxA1) modulates early-phase gestation and offspring sex-ratio skewing. J Cell Physiol vol. 233, (9) 6591-6603.
10.1002/jcp.26258
Patruno S, Garrido-Mesa J, Romano M, PERRETTI M, MONTERO MELENDEZ T(2018). Ligand bias and its association with pro-resolving actions of melanocortin drugs. Frontiers in Pharmacology vol. 9, (919)
10.3389/fphar.2018.00919
PITZALIS C, CORSIERO E, JAGEMANN L, PERRETTI M, BOMBARDIERI M(2018). Characterization of a synovial B cell-derived 1 recombinant monoclonal antibody 2 targeting stromal calreticulin in the rheumatoid joints. Journal of Immunology
10.4049/jimmunol.1800346
Piovezan AP, Perretti M(2018). Potential engagement of pathways of the resolution of inflammation as mechanism of action for plants on animal models. J Ethnopharmacol vol. 221, 160-161.
10.1016/j.jep.2017.11.033
Qin CX, Finlayson SB, Al-Sharea A, Tate M, De Blasio MJ, Deo M, Rosli S, Prakoso D et al.(2018). Author Correction: Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo. Sci Rep vol. 8, (1)
10.1038/s41598-018-24994-9
Lashin HMS, Nadkarni S, Oggero S, Jones HR, Knight JC, Hinds CJ, Perretti M(2018). Microvesicle Subsets in Sepsis Due to Community Acquired Pneumonia Compared to Faecal Peritonitis. Shock vol. 49, (4) 393-401.
10.1097/SHK.0000000000000989
Rhys HI, Dell'Accio F, Pitzalis C, Moore A, Norling LV, Perretti M(2018). Neutrophil Microvesicles from Healthy Control and Rheumatoid Arthritis Patients Prevent the Inflammatory Activation of Macrophages. EBioMedicine vol. 29, 60-69.
10.1016/j.ebiom.2018.02.003
Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR et al.(2018). Resolvins suppress tumor growth and enhance cancer therapy. J Exp Med vol. 215, (1) 115-140.
10.1084/jem.20170681
Perretti M, Norling LV(2017). Actions of SPM in regulating host responses in arthritis. Mol Aspects Med vol. 58, 57-64.
10.1016/j.mam.2017.04.005
Qin CX, Finlayson SB, Ai-Sharea A, Tate M, De Blasio MJ, Deo M, Rosli S, Prakoso D et al.(2017). Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo. Sci Rep vol. 7, (1) 16615-16615.
10.1038/s41598-017-16317-1
Simeoli R, Montague K, Jones HR, Castaldi L, Chambers D, Kelleher JH, Vacca V, Pitcher T et al.(2017). Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma. Nat Commun vol. 8, (1) 1778-1778.
10.1038/s41467-017-01841-5
Petri MH, Laguna-Fernandez A, Arnardottir H, Wheelock CE, Perretti M, Hansson GK, Bäck M(2017). Aspirin-triggered lipoxin A4 inhibits atherosclerosis progression in apolipoprotein E-/- mice. Br J Pharmacol vol. 174, (22) 4043-4054.
10.1111/bph.13707
Lima KM, Vago JP, Caux TR, Negreiros-Lima GL, Sugimoto MA, Tavares LP, Arribada RG, Carmo AAF et al.(2017). The resolution of acute inflammation induced by cyclic AMP is dependent on annexin A1. J Biol Chem vol. 292, (33) 13758-13773.
10.1074/jbc.M117.800391
Perretti M, Montero-Melendez T(2017). Resolution in an 'over-inflamed' era. Biochemist vol. 39, (4) 4-7.
Simeoli R, Mattace Raso G, Pirozzi C, Lama A, Santoro A, Russo R, Montero-Melendez T, Berni Canani R et al.(2017). An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis. Br J Pharmacol vol. 174, (11) 1484-1496.
10.1111/bph.13637
Gittens BR, Bodkin JV, Nourshargh S, Perretti M, Cooper D(2017). Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation. J Immunol vol. 198, (11) 4458-4469.
10.4049/jimmunol.1600709
Piovezan AP, Batisti AP, Benevides MLACS, Turnes BL, Martins DF, Kanis L, Duarte ECW, Cavalheiro AJ et al.(2017). Hydroalcoholic crude extract of Casearia sylvestris Sw. reduces chronic post-ischemic pain by activation of pro-resolving pathways. J Ethnopharmacol vol. 204, 179-188.
10.1016/j.jep.2017.03.059
Perretti M, Di Filippo C, D'Amico M, Dalli J(2017). Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide. PLoS One vol. 12, (4) Article 0175786, e0175786-e0175786.
10.1371/journal.pone.0175786
Brod S, Gobbetti T, Gittens B, Ono M, Perretti M, D'Acquisto F(2017). The impact of environmental enrichment on the murine inflammatory immune response. JCI Insight vol. 2, (7)
10.1172/jci.insight.90723
Kaneva MK, Greco KV, Headland SE, Montero-Melendez T, Mori P, Greenslade K, Pitzalis C, Moore A et al.(2017). Identification of Novel Chondroprotective Mediators in Resolving Inflammatory Exudates. J Immunol vol. 198, (7) 2876-2885.
10.4049/jimmunol.1601111
Montero-Melendez T, Forfar RAE, Cook JM, Jerman JC, Taylor DL, Perretti M(2017). Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3. Cell Mol Life Sci vol. 74, (7) 1335-1345.
10.1007/s00018-016-2419-3
PERRETTI M, Dalli J, Colas R, Federici Canova D, Gobbetti T(2017). Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection. Proceedings of the National Academy of Sciences of the United States of America vol. 114, (15) 3963-3968.
10.1073/pnas.1617290114
Perretti M, Cooper D, Dalli J, Norling LV(2017). Immune resolution mechanisms in inflammatory arthritis. Nat Rev Rheumatol vol. 13, (2) 87-99.
10.1038/nrrheum.2016.193
Bruzzi S, Sutti S, Toscani A, Bozzola C, Reutelingsperger C, Kusters D, Mcarthur S, Perretti M et al. (2017). Annexin A1 supplementation prevents the progression to fibrosis of nonalcoholic steatoepatitis (NASH). JOURNAL OF HEPATOLOGY. Conference: The International Liver Congress 2017 vol. 66, S608-S608.
10.1016/S0168-8278(17)31653-7
NADKARNI SA, Smith J, Mauro C, Marelli-Berg FM, Perretti M, Sferruzzi-Perri AN, Ledwozyw A, Kishore M et al.(2016). Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy. Proceedings of the National Academy of Sciences of USA
10.1073/pnas.1611944114
Machado ID, Spatti M, Hastreiter A, Santin JR, Fock RA, Gil CD, Oliani SM, Perretti M et al.(2016). Annexin A1 Is a Physiological Modulator of Neutrophil Maturation and Recirculation Acting on the CXCR4/CXCL12 Pathway. J Cell Physiol vol. 231, (11) 2418-2427.
10.1002/jcp.25346
Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M, Serhan CN(2016). Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. Journal of Immunology vol. 197, (6) 2362-2368.
10.4049/jimmunol.1502268
Di Perna L, Gesualdo C, Maisto R, Di Filippo C, Perretti M, Testa F, Rossi S, D'amico M et al. (2016). Activation of melanocortin receptors Mc1 and Mc5 attenuates retinal damage in experimental diabetic retinopathy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. vol. 57,
Madeira MFM, Queiroz-Junior CM, Montero-Melendez T, Werneck SMC, Correa JD, Soriani FM, Garlet GP, Souza DG et al.(2016). Melanocortin agonism as a viable strategy to control alveolar bone loss induced by oral infection. The FASEB Journal
10.1096/fj.201600790R
Eldridge S, Nalesso G, Ismail H, Vicente-Greco K, Kabouridis P, Ramachandran M, Niemeier A, Herz J et al.(2016). Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo. Ann Rheum Dis vol. 75, (6) 1228-1235.
10.1136/annrheumdis-2015-207316
Norling L, Headland S, Dalli J, Arnardottir H, Jones H, Haworth O, Serhan C, Perretti M (2016). PRO-RESOLVING AND CARTILAGE-PROTECTIVE ACTIONS OF RESOLVIN D1 IN INFLAMMATORY ARTHRITIS. ANNALS OF THE RHEUMATIC DISEASES. Conference: EULAR vol. 75, 673-673.
10.1136/annrheumdis-2016-eular.6116
MONTERO MELENDEZ T, Buckley CD, Filer A, Turner JD, Perretti M (2016). TARGETING SYNOVIAL FIBROBLASTS WITH MELANOCORTIN DRUGS. ANNALS OF THE RHEUMATIC DISEASES. Conference: Annual European Congress of Rheumatology EULAR 2016 vol. 75, 923-923.
10.1136/annrheumdis-2016-eular.3231
Vital SA, Becker F, Holloway PM, Russell J, Perretti M, Granger DN, Gavins FNE(2016). Fpr2/ALX Regulates Neutrophil-Platelet Aggregation and Attenuates Cerebral Inflammation: Impact for Therapy in Cardiovascular Disease. Circulation Article CIRCULATIONAHA.115.0,
10.1161/CIRCULATIONAHA.115.020633
Chen J, Kieswich J, Chiazza F, Moyes A, Gobbetti T, Purvis G, Salvatori D, Patel N et al.(2016). IkB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD. Journal of the American Society of Nephrology
10.1681/ASN.2015060670
Brancaleone V, Esposito I, Gargiulo A, Vellecco V, Asimakopoulou A, Citi V, Calderone V, Gobbetti T et al.(2016). D-Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-γ-lyase. Br J Pharmacol vol. 173, (9) 1556-1565.
10.1111/bph.13459
Sugimoto MA, Sousa LP, Pinho V, Perretti M, Teixeira MM(2016). Resolution of Inflammation: What Controls Its Onset?. Frontiers in Immunology vol. 7,
10.3389/fimmu.2016.00160
Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al.(2016). Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis. JCI Insight vol. 1, (5)
10.1172/jci.insight.85922
Gobbetti T, Toller-Kawahisa JE, Cooray SN, Flower RJ, Perretti M (2016). New link between the AnxA1/FPR2 system and activation of AMP-activated protein kinase. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. vol. 46, 93-93.
Jones HR, Robb CT, Perretti M, Rossi AG(2016). The role of neutrophils in inflammation resolution. Seminars in Immunology vol. 28, (2) 137-145.
10.1016/j.smim.2016.03.007
Sinniah A, Yazid S, Perretti M, Solito E, Flower RJ(2016). The role of the Annexin-A1/FPR2 system in the regulation of mast cell degranulation provoked by compound 48/80 and in the inhibitory action of nedocromil. Int Immunopharmacol vol. 32, 87-95.
10.1016/j.intimp.2016.01.003
Vago JP, Tavares LP, Sugimoto MA, Lima GLN, Galvão I, de Caux TR, Lima KM, Ribeiro ALC et al.(2016). Proresolving Actions of Synthetic and Natural Protease Inhibitors Are Mediated by Annexin A1. J Immunol vol. 196, (4) 1922-1932.
10.4049/jimmunol.1500886
Rossi S, Maisto R, Gesualdo C, Trotta MC, Ferraraccio F, Kaneva MK, Getting SJ, Surace E et al.(2016). Activation of Melanocortin Receptors MC 1 and MC 5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy. Mediators Inflamm vol. 2016,
10.1155/2016/7368389
Headland SE, Jones HR, Norling LV, Kim A, Souza PR, Corsiero E, Gil CD, Nerviani A et al.(2015). Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis. Sci Transl Med vol. 7, (315)
10.1126/scitranslmed.aac5608
Federici Canova D, Pavlov AM, Norling LV, Gobbetti T, Brunelleschi S, Le Fauder P, Cenac N, Sukhorukov GB et al.(2015). Alpha-2-macroglobulin loaded microcapsules enhance human leukocyte functions and innate immune response. J Control Release vol. 217, 284-292.
10.1016/j.jconrel.2015.09.021
Perretti M, Leroy X, Bland EJ, Montero-Melendez T(2015). Resolution Pharmacology: Opportunities for Therapeutic Innovation in Inflammation. Trends Pharmacol Sci vol. 36, (11) 737-755.
10.1016/j.tips.2015.07.007
Chen J, Kieswich J, Chiazza F, Gobbetti T, Patel NSA, Perretti M, Collino M, Yaqoob MM et al. (2015). THE CARDIAC DYSFUNCTION CAUSED BY SEPSIS IN ANIMALS WITH CHRONIC KIDNEY DISEASE IS ATTENUATED BY INHIBITING I kappa B KINASE. SHOCK. vol. 44, 16-16.
Holloway PM, Durrenberger PF, Trutschl M, Cvek U, Cooper D, Orr AW, Perretti M, Getting SJ et al.(2015). Both MC1 and MC3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion-Induced Neutrophil Recruitment. Arterioscler Thromb Vasc Biol vol. 35, (9) 1936-1944.
10.1161/ATVBAHA.115.305348
McArthur S, Gobbetti T, Kusters DHM, Reutelingsperger CP, Flower RJ, Perretti M(2015). Definition of a Novel Pathway Centered on Lysophosphatidic Acid To Recruit Monocytes during the Resolution Phase of Tissue Inflammation. J Immunol vol. 195, (3) 1139-1151.
10.4049/jimmunol.1500733
Haas R, Smith J, Rocher-Ros V, Nadkarni S, Montero-Melendez T, D'Acquisto F, Bland EJ, Bombardieri M et al.(2015). Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions. PLoS Biol vol. 13, (7)
10.1371/journal.pbio.1002202
Trentin PG, Ferreira TPT, Arantes ACS, Ciambarella BT, Cordeiro RSB, Flower RJ, Perretti M, Martins MA et al.(2015). Annexin A1 mimetic peptide controls the inflammatory and fibrotic effects of silica particles in mice. Br J Pharmacol vol. 172, (12) 3058-3071.
10.1111/bph.13109
Chen J, Kieswich J, Chiazza F, Gobbetti T, Patel NS, Perretti M, Collino M, Yaqoob MM et al. (2015). THE CARDIAC DYSFUNCTION CAUSED BY SEPSIS IN ANIMALS WITH CHRONIC KIDNEY DISEASE IS ATTENUATED BY INHIBITING I kappa B KINASE. SHOCK. vol. 43, 92-93.
Perretti M(2015). The resolution of inflammation: New mechanisms in patho-physiology open opportunities for pharmacology. Semin Immunol vol. 27, (3) 145-148.
10.1016/j.smim.2015.06.001
Flower RJ, Perretti M(2015). 'Annexins' themed section. Br J Pharmacol vol. 172, (7) 1651-1652.
10.1111/bph.13089
Montero-Melendez T, Gobbetti T, Cooray SN, Jonassen TE, Perretti M(2015). Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol vol. 194, (7) 3381-3388.
10.4049/jimmunol.1402645
Amoruso A, Fresu LG, Dalli J, Miglietta D, Bardelli C, Federici Canova D, Perretti M, Brunelleschi S(2015). Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen. Life Sci vol. 126, 28-36.
10.1016/j.lfs.2015.01.025
Leoni G, Neumann P-A, Kamaly N, Quiros M, Nishio H, Jones HR, Sumagin R, Hilgarth RS et al.(2015). Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest vol. 125, (3) 1215-1227.
10.1172/JCI76693
Fredman G, Kamaly N, Spolitu S, Milton J, Ghorpade D, Chiasson R, Kuriakose G, Perretti M et al.(2015). Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice. Sci Transl Med vol. 7, (275)
10.1126/scitranslmed.aaa1065
Gobbetti T, Ducheix S, le Faouder P, Perez T, Riols F, Boue J, Bertrand-Michel J, Dubourdeau M et al.(2015). Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor. Br J Pharmacol vol. 172, (3) 910-923.
10.1111/bph.12957
Petri MH, Laguna-Fernandez A, Tseng C-N, Hedin U, Perretti M, Bäck M(2015). Aspirin-triggered 15-epi-lipoxin A₄ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation. Int J Cardiol vol. 179, 370-372.
10.1016/j.ijcard.2014.11.010
Kusters DHM, Chatrou ML, Willems BAG, De Saint-Hubert M, Bauwens M, van der Vorst E, Bena S, Biessen EAL et al.(2015). Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet. PLoS One vol. 10, (6)
10.1371/journal.pone.0130484
Gobbetti T, Coldewey SM, Chen J, McArthur S, le Faouder P, Cenac N, Flower RJ, Thiemermann C et al.(2014). Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proc Natl Acad Sci U S A vol. 111, (52) 18685-18690.
10.1073/pnas.1410938111
Thompson D, McArthur S, Hislop JN, Flower RJ, Perretti M(2014). Identification of a novel recycling sequence in the C-tail of FPR2/ALX receptor: association with cell protection from apoptosis. J Biol Chem vol. 289, (52) 36166-36178.
10.1074/jbc.M114.612630
Machado ID, Santin JR, Drewes CC, Gil CD, Oliani SM, Perretti M, Farsky SHP(2014). Alterations in the profile of blood neutrophil membrane receptors caused by in vivo adrenocorticotrophic hormone actions. Am J Physiol Endocrinol Metab vol. 307, (9) E754-E763.
10.1152/ajpendo.00227.2014
Fredman G, Ozcan L, Spolitu S, Hellmann J, Spite M, Backs J, Tabas I (2014). Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway. Proc Natl Acad Sci U S A. vol. 111, 14530-14535.
10.1073/pnas.1410851111
Greco KV, Nalesso G, Kaneva MK, Sherwood J, Iqbal AJ, Moradi-Bidhendi N, Dell'Accio F, Perretti M(2014). Analyses on the mechanisms that underlie the chondroprotective properties of calcitonin. Biochem Pharmacol vol. 91, (3) 348-358.
10.1016/j.bcp.2014.07.034
Brancaleone V, Mitidieri E, Flower RJ, Cirino G, Perretti M(2014). Annexin A1 mediates hydrogen sulfide properties in the control of inflammation. J Pharmacol Exp Ther vol. 351, (1) 96-104.
10.1124/jpet.114.217034
Burgmaier M, Schutters K, Willems B, Van der Vorst EPC, Kusters D, Chatrou M, Norling L, Biessen EAL et al.(2014). AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(-/-) mice. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE vol. 18, (10) 2117-2124.
10.1111/jcmm.12374
Lashin H, Nadkarni S, Hinds C, Perretti M (2014). IN PATIENTS WITH SEVERE SEPSIS MICROPARTICLE PROFILES DIFFER ACCORDING TO THE SOURCE OF INFECTION. INTENSIVE CARE MEDICINE. vol. 40, S239-S240.
Montero-Melendez T, Madeira MFM, Norling LV, Alsam A, Curtis MA, da Silva TA, Perretti M(2014). Association between periodontal disease and inflammatory arthritis reveals modulatory functions by melanocortin receptor type 3. Am J Pathol vol. 184, (8) 2333-2341.
10.1016/j.ajpath.2014.04.009
Locatelli I, Sutti S, Jindal A, Vacchiano M, Bozzola C, Reutelingsperger C, Kusters D, Bena S et al.(2014). Endogenous Annexin A1 Is a Novel Protective Determinant in Nonalcoholic Steatohepatitis in Mice. HEPATOLOGY vol. 60, (2) 531-544.
10.1002/hep.27141
Montero-Melendez T, Perretti M(2014). Gapdh gene expression is modulated by inflammatory arthritis and is not suitable for qPCR normalization. Inflammation vol. 37, (4) 1059-1069.
10.1007/s10753-014-9829-x
Ahmed TJ, Kaneva MK, Pitzalis C, Cooper D, Perretti M(2014). Resolution of inflammation: examples of peptidergic players and pathways. Drug Discov Today vol. 19, (8) 1166-1171.
10.1016/j.drudis.2014.05.020
Cash JL, Norling LV, Perretti M(2014). Resolution of inflammation: targeting GPCRs that interact with lipids and peptides. Drug Discov Today vol. 19, (8) 1186-1192.
10.1016/j.drudis.2014.06.023
Farsky SHP, Santin JR, Takahama C, Machado ID, Teixeira S, Muscara MN, Pitta IR, Solito E et al. (2014). ANNEXIN A1 AND PPAR gamma ON RESOLUTION OF INFLAMMATION. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. vol. 115, 286-286.
Montero-Melendez T, Perretti M(2014). Connections in pharmacology: innovation serving translational medicine. Drug Discov Today vol. 19, (7) 820-823.
10.1016/j.drudis.2013.11.022
Headland SE, Jones HR, D'Sa ASV, Perretti M, Norling LV(2014). Cutting-edge analysis of extracellular microparticles using ImageStream(X) imaging flow cytometry. Sci Rep vol. 4,
10.1038/srep05237
Hardy W, Wright F, Hawtree S, Fearon U, Veale D, Perretti M, Wilson A, Muthana M (2014). HYPOXIA-INDUCIBLE FACTOR 2a REGULATES MACROPHAGE FUNCTION IN RHEUMATOID ARTHRITIS. ANNALS OF THE RHEUMATIC DISEASES. vol. 73, 174-174.
10.1136/annrheumdis-2014-eular.4257
Old EA, Nadkarni S, Grist J, Gentry C, Bevan S, Kim K-W, Mogg AJ, Perretti M et al.(2014). Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain. JOURNAL OF CLINICAL INVESTIGATION vol. 124, (5) 2023-2036.
10.1172/JCI71389
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M (2014). NEUTROPHILS IN GCA. RHEUMATOLOGY. vol. 53, 9-9.
Fu H, Kishore M, Gittens B, Wang G, Coe D, Komarowska I, Infante E, Ridley AJ et al.(2014). Self-recognition of the endothelium enables regulatory T-cell trafficking and defines the kinetics of immune regulation. Nat Commun vol. 5,
10.1038/ncomms4436
Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M(2014). Investigational analysis reveals a potential role for neutrophils in giant-cell arteritis disease progression. Circ Res vol. 114, (2) 242-248.
10.1161/CIRCRESAHA.114.301374
Gallo I, Rattazzi L, Piras G, Gobbetti T, Panza E, Perretti M, Dalley JW, D'Acquisto F(2014). Formyl peptide receptor as a novel therapeutic target for anxiety-related disorders. PLoS One vol. 9, (12)
10.1371/journal.pone.0114626
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Cooray SN, Gobbetti T, Montero-Melendez T, McArthur S, Thompson D, Clark AJL, Flower RJ, Perretti M(2013). Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci U S A vol. 110, (45) 18232-18237.
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Cash JL, Bena S, Headland SE, McArthur S, Brancaleone V, Perretti M(2013). Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23. EMBO Rep vol. 14, (11) 999-1007.
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Brancaleone V, Flower RJ, Cirino G, Perretti M (2013). Annexin A1 (AnxA1) mediates hydrogen sulfide (H2S) effects in the control of inflammation. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. vol. 31, S21-S22.
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Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M(2013). Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Mol Cell Proteomics vol. 12, (8) 2205-2219.
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Godson C, Perretti M(2013). Novel pathways in the yin-yang of immunomodulation. CURRENT OPINION IN PHARMACOLOGY vol. 13, (4) 543-546.
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Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S et al.(2013). A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation. Blood vol. 122, (4) 608-617.
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Iqbal AJ, Cooper D, Vugler A, Gittens BR, Moore A, Perretti M(2013). Endogenous galectin-1 exerts tonic inhibition on experimental arthritis. J Immunol vol. 191, (1) 171-177.
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Dalli J, Consalvo AP, Ray V, Di Filippo C, D'Amico M, Mehta N, Perretti M(2013). Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A4 receptor. J Immunol vol. 190, (12) 6478-6487.
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Norling LV, Perretti M(2013). The role of omega-3 derived resolvins in arthritis. Curr Opin Pharmacol vol. 13, (3) 476-481.
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Nusrat A, Leoni G, Neumann P-A, Alam A, Lambeth D, Hilgarth R, Kusters D, Reutelingsperger C et al. (2013). Annexin 1 in microparticles promotes intestinal mucosal wound repair during inflammation. JOURNAL OF IMMUNOLOGY. vol. 190,
Fowkes RC, Moradi-Bidhendi N, Branceleone V, Zariwala MG, Brady D, Jessop DS, Perretti M, Renshaw D(2013). Annexin-A1 protein and its relationship to cortisol in human saliva. PSYCHONEUROENDOCRINOLOGY vol. 38, (5) 722-727.
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Ortega-Gomez A, Perretti M, Soehnlein O(2013). Resolution of inflammation: an integrated view. EMBO MOLECULAR MEDICINE vol. 5, (5) 661-674.
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Ryan SM, McMorrow J, Umerska A, Patel HB, Kornerup KN, Tajber L, Murphy EP, Perretti M et al.(2013). An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis. J Control Release vol. 167, (2) 120-129.
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Patel HB, Bombardieri M, Pitzalis C, Perretti M (2013). Activation of Melanocortin Receptor 3 as a new strategy to control experimental and rheumatoid arthritis. FASEB JOURNAL. vol. 27,
Cooray SN, Clark A, Flower R, Perretti M (2013). Agonist-induced conformational change of the Formyl Peptide Receptors. FASEB JOURNAL. vol. 27,
Thompson D, Perretti M (2013). Differential Trafficking of the FPR2/ALX receptor in response to endogenous or synthetic ligands. FASEB JOURNAL. vol. 27,
Leoni G, Neumann P-A, Alam A, Hilgarth RS, Lambeth DJ, Kusters D, Reutelingsperger C, Perretti M et al. (2013). Epithelial wound repair: insights into the multifaceted roles of Annexin A1. FASEB JOURNAL. vol. 27,
Montero-Melendez T, Dalli J, Perretti M(2013). Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors. Cell Death Differ vol. 20, (4) 567-575.
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Gittens B, Perretti M, Cooper D (2013). Investigating Novel Roles for Exogenous and Endogenous Galectin-3 in Controlling Vascular Inflammation. FASEB JOURNAL. vol. 27,
Martin K, Perretti M, Ahluwalia A (2013). Kinin B1 receptor regulates inflammatory cell recruitment during low laminar shear stress. FASEB JOURNAL. vol. 27,
Perretti M, Bena S, Brancaleone V, Flower RJ (2013). Modulation of the receptor ALX/FPR2 in vascular inflammation. FASEB JOURNAL. vol. 27,
Perretti M, Dalli J, Norling LV, Montero-Melendez T, Hinds C (2013). Neutrophil Microparticles are heterogenous in content and function. FASEB JOURNAL. vol. 27,
Headland SE, Dell'Accio F, Perretti M (2013). Neutrophil-Derived Microparticles as Novel Effectors in Joint Disease. FASEB JOURNAL. vol. 27,
Norling LV, Perretti M (2013). Omega-3 derived Resolvin D1 reduces the severity of inflammatory arthritis. FASEB JOURNAL. vol. 27,
Poliselli Farsky SH, Machado ID, Santin JR, Ferraz VP, Gil CD, Oliani SM, Perretti M (2013). Role of cytosolic glucocorticoid receptor and Annexin-A1 on neutrophil traffic from bone marrow into blood: SDF-1alpha/CXCR-4/CXCR-2 axis. FASEB JOURNAL. vol. 27,
Rhodes DH, Pini M, Castellanos KJ, Montero-Melendez T, Cooper D, Perretti M, Fantuzzi G(2013). Adipose tissue-specific modulation of galectin expression in lean and obese mice: evidence for regulatory function. Obesity (Silver Spring) vol. 21, (2) 310-319.
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Leoni G, Alam A, Neumann P-A, Lambeth JD, Cheng G, McCoy J, Hilgarth RS, Kundu K et al.(2013). Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair. JOURNAL OF CLINICAL INVESTIGATION vol. 123, (1) 443-454.
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Kosicka A, Cunliffe AD, Mackenzie R, Zariwala MG, Perretti M, Flower RJ, Renshaw D(2013). Attenuation of plasma annexin A1 in human obesity. FASEB JOURNAL vol. 27, (1) 368-378.
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Sampaio ALF, Dalli J, Brancaleone V, D'Acquisto F, Perretti M, Wheatley C(2013). Biphasic modulation of NOS expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: downstream regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 expression. Mediators Inflamm vol. 2013,
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Schutters K, Kusters DHM, Chatrou MLL, Montero-Melendez T, Donners M, Deckers NM, Krysko DV, Vandenabeele P et al.(2013). Cell surface-expressed phosphatidylserine as therapeutic target to enhance phagocytosis of apoptotic cells. Cell Death Differ vol. 20, (1) 49-56.
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Norling LV, Perretti M(2013). Control of myeloid cell trafficking in resolution. J Innate Immun vol. 5, (4) 367-376.
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Ahmed TJ, Montero-Melendez T, Perretti M, Pitzalis C(2013). Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin Peptides. Int J Inflam vol. 2013,
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Montero-Meléndez T, Llor X, García-Planella E, Perretti M, Suárez A(2013). Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling. PLoS One vol. 8, (10)
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Pang J, Rhodes DH, Pini M, Akasheh RT, Castellanos KJ, Cabay RJ, Cooper D, Perretti M et al.(2013). Increased adiposity, dysregulated glucose metabolism and systemic inflammation in Galectin-3 KO mice. PLoS One vol. 8, (2)
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Viiri LE, Full LE, Navin TJ, Begum S, Didangelos A, Astola N, Berge RK, Seppala I et al.(2013). Smooth muscle cells in human atherosclerosis: Proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY vol. 54, 65-72.
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Al-Kashi A, Montero-Melendez T, Moradi-Bidhendi N, Gilligan JP, Mehta N, Perretti M(2013). The calcitonin and glucocorticoids combination: mechanistic insights into their class-effect synergy in experimental arthritis. PLoS One vol. 8, (2)
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Vincent TL, Williams RO, Maciewicz R, Silman A, Garside P, Arthritis Research UK animal models working group(2012). Mapping pathogenesis of arthritis through small animal models. Rheumatology (Oxford) vol. 51, (11) 1931-1941.
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Cardini S, Dalli J, Fineschi S, Perretti M, Lungarella G, Lucattelli M(2012). Genetic Ablation of the Fpr1 Gene Confers Protection from Smoking-Induced Lung Emphysema in Mice. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY vol. 47, (3) 332-339.
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Perretti M(2012). Editorial: to resolve or not to resolve: annexin A1 pushes resolution on track. J Leukoc Biol vol. 92, (2) 245-247.
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Headland S, Perretti M (2012). Neutrophil microparticles as novel effectors of joint disease. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 93, A30-A30.
Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M(2012). Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol vol. 32, (8) 1970-1978.
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Bena S, Brancaleone V, Wang JM, Perretti M, Flower RJ(2012). Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling. J Biol Chem vol. 287, (29) 24690-24697.
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Kabouridis PS, Pimentel TA, Brancaleone V, D'Acquisto F, Oliani SM, Perretti M, Jury EC(2012). Distinct localization of T cell Agrin during antigen presentation--evidence for the expression of Agrin receptor(s) in antigen-presenting cells. FEBS J vol. 279, (13) 2368-2380.
10.1111/j.1742-4658.2012.08615.x
Vong L, Ferraz JGP, Dufton N, Panaccione R, Beck PL, Sherman PM, Perretti M, Wallace JL(2012). Up-Regulation of Annexin-A1 and Lipoxin A(4) in Individuals with Ulcerative Colitis May Promote Mucosal Homeostasis. PLOS ONE vol. 7, (6) Article ARTN e39244,
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Clark AK, Grist J, Al-Kashi A, Perretti M, Malcangio M(2012). Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model. ARTHRITIS AND RHEUMATISM vol. 64, (6) 2038-2047.
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Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FNE, Cooper D, Gould D et al.(2012). The peritoneal tumour microenvironment of high-grade serous ovarian cancer. J Pathol vol. 227, (2) 136-145.
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Liverani E, Banerjee S, Roberts W, Naseem KM, Perretti M(2012). Prednisolone exerts exquisite inhibitory properties on platelet functions. Biochem Pharmacol vol. 83, (10) 1364-1373.
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Patel HB, Kornerup KN, Sampaio ALFS, D'Acquisto F, Seed MP, Girol AP, Gray M, Pitzalis C et al.(2012). The impact of endogenous annexin A1 on glucocorticoid control of inflammatory arthritis. Annals of the Rheumatic Diseases
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Headland SE, Perretti M (2012). NEUTROPHIL MICROPARTICLES AS POTENTIAL NOVEL EFFECTORS OF JOINT DISEASE. RHEUMATOLOGY. vol. 51, 47-47.
Norling L, Dalli J, Flower R, Serhan C, Perretti M (2012). RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS. RHEUMATOLOGY. vol. 51, 47-48.
Cooper D, Iqbal AJ, Gittens BR, Cervone C, Perretti M(2012). The effect of galectins on leukocyte trafficking in inflammation: sweet or sour?. Ann N Y Acad Sci vol. 1253, 181-192.
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Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD et al.(2012). Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves. FASEB J vol. 26, (3) 1064-1076.
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Di Filippo C, Perretti M, Rossi F, Ferraraccio F, Motterlini R, D'Amico M(2012). Acute myocardial infarction in streptozotocin-induced hyperglycaemic rats: protection by a carbon monoxide-releasing molecule (CORM-3). NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY vol. 385, (2) 137-144.
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de Lima CB, Tamura EK, Montero-Melendez T, Palermo-Neto J, Perretti M, Markus RP, Farsky SHP(2012). Actions of translocator protein ligands on neutrophil adhesion and motility induced by G-protein coupled receptor signaling. Biochem Biophys Res Commun vol. 417, (2) 918-923.
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Dalli J, Montero-Melendez T, McArthur S, Perretti M(2012). Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol vol. 3,
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Dalli J, Jones CP, Cavalcanti DM, Farsky SH, Perretti M, Rankin SM(2012). Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow. FASEB J vol. 26, (1) 387-396.
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Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed M, Perretti M, Chernajovsky Y(2012). Molecular engineering of short half-life small peptides (VIP, αMSH and γ₃MSH) fused to latency-associated peptide results in improved anti-inflammatory therapeutics. Ann Rheum Dis vol. 71, (1) 143-149.
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Greco KV, Iqbal AJ, Rattazzi L, Nalesso G, Moradi-Bidhendi N, Moore AR, Goldring MB, Dell'Accio F et al.(2011). High density micromass cultures of a human chondrocyte cell line: a reliable assay system to reveal the modulatory functions of pharmacological agents. Biochem Pharmacol vol. 82, (12) 1919-1929.
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Nadkarni S, Cooper D, Brancaleone V, Bena S, Perretti M(2011). Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes. Arterioscler Thromb Vasc Biol vol. 31, (11) 2749-2759.
10.1161/ATVBAHA.111.235176
Damazo AS, Sampaio AL, Nakata CM, Flower RJ, Perretti M, Oliani SM(2011). Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis. BMC Immunol vol. 12,
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Nadkarni S, Hollywood J, Mason JC, Dasgupta B, Perretti M (2011). Annexin-A1: A Potential Novel Biomarker in Giant Cell Arteritis. ARTHRITIS AND RHEUMATISM. vol. 63, S593-S593.
Patel HB, Montero-Melendez T, Greco KV, Perretti M(2011). Melanocortin receptors as novel effectors of macrophage responses in inflammation. Frontiers in Immunology vol. 2, Article 41, 1-6.
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Montero-Melendez T, Patel HB, Seed M, Nielsen S, Jonassen TEN, Perretti M(2011). The melanocortin agonist AP214 exerts anti-inflammatory and proresolving properties. Am J Pathol vol. 179, (1) 259-269.
10.1016/j.ajpath.2011.03.042
Greco KV, Moore A, Dell'Accio F, Perretti M (2011). 3D CULTURES OF C-28/I2 CHONDROCYTES TO STUDY CHONDROCYTE BIOLOGY AND THERAPEUTIC DEVELOPMENT. INFLAMMATION RESEARCH. vol. 60, 283-283.
Brancaleone V, Sampaio AL, Cirino G, Flower RJ, Perretti M (2011). A NOVEL CROSS-TALK IN RESOLUTION: H2S ACTIVATES THE ANNEXIN A1 PATHWAY. INFLAMMATION RESEARCH. vol. 60, 49-49.
Iqbal AJ, Cooper D, Vugler AD, Moore A, Perretti M (2011). ENDOGENOUS GALECTIN-1 INHIBITS EXPERIMENTAL ARTHRITIS: A POTENTIAL SWEET THERAPEUTIC TARGET?. INFLAMMATION RESEARCH. vol. 60, 186-187.
Rhodes D, Pini M, Montero-Melendez T, Perretti M, Fantuzzi G (2011). EXPRESSION OF ANNEXIN A1 IN ADIPOSE TISSUE IS DISSOCIATED FROM MACROPHAGE INFILTRATION DURING DEVELOPMENT OF OBESITY IN MICE. INFLAMMATION RESEARCH. vol. 60, 261-261.
Cooper D, Iqbal AJ, Niki T, Hirashima M, Perretti M (2011). GALECTIN-9: SWEETENING LEUKOCYTE RECRUITMENT. INFLAMMATION RESEARCH. vol. 60, 87-88.
Perretti M (2011). GLUCOCORTICOIDS CUT SHORT THE CONCERT OF INFLAMMATION THROUGH THE RELEASE OF ANNEXIN A1. INFLAMMATION RESEARCH. vol. 60, 16-17.
Montero-Melendez T, Jonassen T, Seed M, Perretti M (2011). MC3 AGONISTS AS NOVEL PRO-RESOLVING THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 269-269.
Greco KV, Montero-Melendez T, Patel H, Perretti M (2011). MELANOCORTIN RECEPTOR AGONISTS ARE NOVEL CHONDROPROTECTIVE THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 273-273.
Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed MP, Perretti M, Chernajovsky Y (2011). MOLECULAR ENGINEERING OF SHORT HALF LIFE SMALL PEPTIDES (VIP, alpha MSH AND gamma 3MSH) INTO LATENT ASSOCIATED PEPTIDE (LAP) RESULTS IN TARGETED ANTI-INFLAMMATORY AND ANTI-RHEUMATIC THERAPEUTICS. INFLAMMATION RESEARCH. vol. 60, 43-43.
Norling LV, Dalli J, Serhan CN, Perretti M (2011). RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS. INFLAMMATION RESEARCH. vol. 60, 60-60.
Roviezzo F, Brancaleone V, De Gruttola L, Vellecco V, Bucci M, D'Agostino B, Cooper D, Sorrentino R et al.(2011). Sphingosine-1-phosphate modulates vascular permeability and cell recruitment in acute inflammation in vivo. J Pharmacol Exp Ther vol. 337, (3) 830-837.
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Maione F, Cicala C, Liverani E, Mascolo N, Perretti M, D'Acquisto F(2011). IL-17A increases ADP-induced platelet aggregation. Biochem Biophys Res Commun vol. 408, (4) 658-662.
10.1016/j.bbrc.2011.04.080
Norling LV, Spite M, Yang R, Flower RJ, Perretti M, Serhan CN(2011). Cutting Edge: Humanized Nano-Proresolving Medicines Mimic Inflammation-Resolution and Enhance Wound Healing. J IMMUNOL vol. 186, (10) 5543-5547.
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Norling LV, Spite M, Yang R, Flower RJ, Perretti M, Serhan CN(2011). Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing. J Immunol vol. 186, (10) 5543-5547.
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Velmurugan S, Kapil V, McKnight AHO, Aboud Z, Davies S, Milsom AB, Pearl V, Liverani E et al. (2011). Dietary nitrate attenuates platelet reactivity: Role of the erythrocyte and influence of sex. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. vol. 24, S35-S36.
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Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ et al.(2011). Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin. Arterioscler Thromb Vasc Biol vol. 31, (5) 1075-1083.
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Brancaleone V, Dalli J, Bena S, Flower RJ, Cirino G, Perretti M(2011). Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature. J Immunol vol. 186, (8) 4905-4914.
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Montero-Melendez T, Patel HB, Perretti M(2011). Role of melanocortin receptors in the regulation of gouty inflammation. Curr Rheumatol Rep vol. 13, (2) 138-145.
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Iqbal AJ, Sampaio ALF, Maione F, Greco KV, Niki T, Hirashima M, Perretti M, Cooper D(2011). Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect. Am J Pathol vol. 178, (3) 1201-1209.
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Gavins FNE, Li G, Russell J, Perretti M, Granger DN(2011). Microvascular thrombosis and CD40/CD40L signaling. J Thromb Haemost vol. 9, (3) 574-581.
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Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al.(2011). Anti-inflammatory role of the murine formyl-peptide receptor 2: Ligand-specific effects on leukocyte responses and experimental in-flammation (The Journal of Immunology (2010) 184, (2611-2619)). Journal of Immunology vol. 186, (4) 2684-2685.
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Allegra M, D'Acquisto F, Tesoriere L, Livrea MA, Perretti M(2011). Cross-talk between minimally primed HL-60 cells and resting HUVEC reveals a crucial role for adhesion over extracellularly released oxidants. BIOCHEM PHARMACOL vol. 81, (3) 396-401.
10.1016/j.bcp.2010.10.018
Colucci M, Mastriota M, Maione F, Di Giannuario A, Mascolo N, Palmery M, Severini C, Perretti M et al.(2011). Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids. PEPTIDES vol. 32, (2) 266-271.
10.1016/j.peptides.2010.11.019
Pimentel TA, Sampaio ALF, D'Acquisto F, Perretti M, Oliani SM(2011). An essential role for mast cells as modulators of neutrophils influx in collagen-induced arthritis in the mouse. Lab Invest vol. 91, (1) 33-42.
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Ryan SM, Patel HB, Kornerup KN, Tajber L, Umerska A, Perretti M, Brayden DJ (2011). Intra-articular delivery of salmon calcitonin nanocomplexes to the K/BXN murine model for treatment of osteoarthritis. 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials.
Patel HB, Montero-Melendez T, Greco KV, Perretti M(2011). Melanocortin receptors as novel effectors of macrophage responses in inflammation. Front Immunol vol. 2,
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Maione F, Paschalidis N, Iqbal AJ, Crompton T, Perretti M, D'Acquisto F(2010). Analysis of the inflammatory response in HY-TCR transgenic mice highlights the pathogenic potential of CD4- CD8- T cells. Autoimmunity vol. 43, (8) 672-681.
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Patel HB, Bombardieri M, Sampaio ALF, D'Acquisto F, Gray M, Grieco P, Getting SJ, Pitzalis C et al.(2010). Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis. FASEB J vol. 24, (12) 4835-4843.
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Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D, Perretti M(2010). Human RCAN3 gene expression and cell growth in endothelial cells. INT J MOL MED vol. 26, (6) 913-918.
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Canaider S, Vettraino M, Norling LV, Spisni E, Facchin F, Cooper D, Perretti M(2010). Human RCAN3 gene expression and cell growth in endothelial cells. Int J Mol Med vol. 26, (6) 913-918.
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Nadkarni S, Brancaleone V, Bena S, Perretti M (2010). Protective effect of oestrogen is mediated by the anti-inflammatory protein annexin-A1. IMMUNOLOGY. vol. 131, 165-166.
Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F(2010). Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature. Blood vol. 116, (20) 4288-4296.
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Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M, Godson C(2010). FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis. FASEB J vol. 24, (11) 4240-4249.
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Sampaio ALF, Zahn G, Leoni G, Vossmeyer D, Christner C, Marshall JF, Perretti M(2010). Inflammation-dependent alpha 5 beta 1 (very late antigen-5) expression on leukocytes reveals a functional role for this integrin in acute peritonitis. J Leukoc Biol vol. 87, (5) 877-884.
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Leoni G, Voisin M-B, Carlson K, Getting S, Nourshargh S, Perretti M(2010). The melanocortin MC(1) receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculature. Br J Pharmacol vol. 160, (1) 171-180.
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Hunter C, Kadakia TB, Cooper D, Perretti M, Schwartz RC, Brown SB(2010). Selective Inhibitors of Kv11.1 Regulate IL-6 Expression by Macrophages in Response to TLR/IL-1R Ligands. THESCIENTIFICWORLDJOURNAL vol. 10, 1580-1596.
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Di Filippo C, Monopoli A, Ongini E, Perretti M, D'Amico M(2010). The Cardio-Protective Properties of Ncx-6550, a Nitric Oxide Donating Pravastatin, in the Mouse. MICROCIRCULATION vol. 17, (6) 417-426.
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Duchene J, Cayla C, Vessillier S, Scotland R, Yamashiro K, Lecomte F, Syed I, Vo P et al.(2009). Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis. Arterioscler Thromb Vasc Biol vol. 29, (11) 1757-1763.
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McColl A, Bournazos S, Franz S, Perretti M, Morgan BP, Haslett C, Dransfield I(2009). Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages. J IMMUNOL vol. 183, (3) 2167-2175.
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Tripatara P, Patel NSA, Brancaleone V, Renshaw D, Rocha J, Sepodes B, Mota-Filipe H, Perretti M et al.(2009). Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study. Eur J Pharmacol vol. 606, (1-3) 205-209.
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Maione F, Paschalidis N, Mascolo N, Dufton N, Perretti M, D'Acquisto F(2009). Interleukin 17 sustains rather than induces inflammation. Biochem Pharmacol vol. 77, (5) 878-887.
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Hecht I, Rong J, Sampaio ALF, Hermesh C, Rutledge C, Shemesh R, Toporik A, Beiman M et al.(2009). A Novel Peptide Agonist of Formyl-Peptide Receptor-Like 1 (ALX) Displays Anti-Inflammatory and Cardioprotective Effects. J PHARMACOL EXP THER vol. 328, (2) 426-434.
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Perretti M, D'Acquisto F(2009). Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Nat Rev Immunol vol. 9, (1) 62-70.
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Gastardelo TS, Damazo AS, Dalli J, Flower RJ, Perretti M, Oliani SM(2009). Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation. AM J PATHOL vol. 174, (1) 177-183.
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Dufton NP, Hannon R, Perretti M, Flower R(2009). Quantitative Analysis of Promoter Activity by Green Fluorescent Protein (GFP) Target/Reporter Strategy in a Novel Transgenic alx/fpr-rs2 Null Mouse. Inflammation Research vol. 58, (2) S252-S255.
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Getting SJ, Riffo-Vasquez Y, Pitchford S, Kaneva M, Grieco P, Page CP, Perretti M, Spina D(2008). A role for MC3R in modulating lung inflammation. PULM PHARMACOL THER vol. 21, (6) 866-873.
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Leoni G, Patel HB, Sampaio ALF, Gavins FNE, Murray JF, Grieco P, Getting SJ, Perretti M(2008). Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion. FASEB J vol. 22, (12) 4228-4238.
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Oliani SM, Ciocca GAP, Pimentel TA, Damazo AS, Gibbs L, Perretti M(2008). Fluctuation of annexin-A1 positive mast cells in chronic granulomatous inflammation. INFLAMM RES vol. 57, (10) 450-456.
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Dalli J, Norling LV, Renshaw D, Cooper D, Leung KY, Perretti M(2008). Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles. BLOOD vol. 112, (6) 2512-2519.
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D'Acquisto F, Perretti M, Flower RJ(2008). Annexin-A1: a pivotal regulator of the innate and adaptive immune systems. BRIT J PHARMACOL vol. 155, (2) 152-169.
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D'Acquisto F, Perretti M(2008). Overview of the role of annexin 1 in the innate and adaptive immune response. Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry vol. 8, (3) 252-258.
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Cooper D, Norling LV, Perretti M(2008). Novel insights into the inhibitory effects of Galectin-1 on neutrophil recruitment under flow. J LEUKOCYTE BIOL vol. 83, (6) 1459-1466.
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Sarndahl E, Bergstrom I, Nijm J, Perretti M, Jonasson L(2008). ENHANCED NEUTROPHIL EXPRESSION OF ANNEXIN-1 IN CORONARY ARTERY DISEASE. ATHEROSCLEROSIS SUPP vol. 9, (1) 15-15.
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D'Acquisto F, Paschalidis N, Raza K, Buckley CD, Flower RJ, Perretti M(2008). Glucocorticoid treatment inhibits annexin-1 expression in rheumatoid arthritis CD4+ T cells. Rheumatology (Oxford) vol. 47, (5) 636-639.
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Dasgupta B, Dalli J, Norling L, Pederzoli-Ribeil M, Hollywood J, D'Acquisto F, Perretti M (2008). Altered expression of annexin 1 and its receptor in neutrophils of patients with giant cell arteritis (GCA) and ANCA associated vasculitis (AAV). RHEUMATOLOGY. vol. 47, II99-II99.
Martin GR, Perretti M, Flower RJ, Wallace JL(2008). Annexin-1 modulates repair of gastric mucosal injury. AM J PHYSIOL-GASTR L vol. 294, (3) G764-G769.
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Norling LV, Sampaio ALF, Cooper D, Perretti M(2008). Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking. FASEB J vol. 22, (3) 682-690.
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Yona S, Lin HH, Dri P, Davies JQ, Hayhoe RPG, Lewis SM, Heinsbroek SEM, Brown KA et al.(2008). Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function. FASEB J vol. 22, (3) 741-751.
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Finney SJ, Anning PB, Cao TV, Perretti M, Evans TW, Burke-Gaffney A(2007). Butanol-extracted lipoteichoic acid induces in vivo leukocyte adhesion. BIOCHEM BIOPH RES CO vol. 364, (4) 831-837.
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O'Sullivan TP, Vallin KSA, Shah STA, Fakhry J, Maderna P, Scannell M, Sampaio ALF, Perretti M et al.(2007). Aromatic lipoxin A(4) and lipoxin B-4 analogues display potent biological activities. J MED CHEM vol. 50, (24) 5894-5902.
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D'Acquisto F, Paschalidis N, Sampaio ALF, Merghani A, Flower RJ, Perretti M(2007). Impaired T cell activation and increased Th2 lineage commitment in Annexin-1-deficient T cells. EUR J IMMUNOL vol. 37, (11) 3131-3142.
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Vong L, D'Acquisto F, Pederzoli-Ribeil M, Lavagno L, Flower RJ, Witko-Sarsat R, Perretti M(2007). Annexin 1 cleavage in activated neutrophils - A pivotal role for proteinase 3. J BIOL CHEM vol. 282, (41) 29998-30004.
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Duchene J, Lecomte F, Ahmed S, Cayla C, Pesquero J, Bader M, Perretti M, Ahluwalia A(2007). A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5. J Immunol vol. 179, (7) 4849-4856.
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Perretti M, Mancini L(2007). Potential of calcitonin as a novel cotreatment for arthritis. Future Rheumatology vol. 2, (5) 493-496.
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Gavins FNE, Dalli J, Flower RJ, Granger DN, Perretti M(2007). Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation. FASEB J vol. 21, (8) 1751-1758.
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Piqueras L, Norlyng L, Perretti M, Li Y, Sanz MJ, Real JT, Warner T, Bishop-Bayley D (2007). PPARb inhibits neutrophil-endothelium interactions under flow. INFLAMM RES. vol. 56, S453-S454.
Urquhart P, Rosignoli G, Cooper D, Motterlini R, Perretti M(2007). Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow. J Pharmacol Exp Ther vol. 321, (2) 656-662.
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John CD, Sahni V, Mehet D, Morris JF, Christian HC, Perretti M, Flower RJ, Solito E et al.(2007). Formyl peptide receptors and the regulation of ACTH secretion: targets for annexin A1, lipoxins, and bacterial peptides. FASEB J vol. 21, (4) 1037-1046.
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Giner RM, Mancini L, Kamal AM, Perretti M(2007). Uneven modulation of the annexin 1 system in osteoblast-like cells by dexamethasone. BIOCHEM BIOPH RES CO vol. 354, (2) 414-419.
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Mancini L, Paul-Clark MJ, Rosignoli G, Hannon R, Martin JE, Macintyre I, Perretti M(2007). Calcitonin and prednisolone display antagonistic actions on bone and have synergistic effects in experimental arthritis. AM J PATHOL vol. 170, (3) 1018-1027.
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D'Acquisto F, Merghani A, Lecona E, Rosignoli G, Raza K, Buckley CD, Flower RJ, Perretti M(2007). Annexin-1 modulates T-cell activation and differentiation. Blood vol. 109, (3) 1095-1102.
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Perretti M(2007). Glucocorticoids in innate immunity: more transactivation than transrepression!. BLOOD vol. 109, (3) 852-853.
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Serhan CN, Brain SD, Buckley CD, Gilroy DW, Haslett C, O'Neill LAJ, Perretti M, Rossi AG et al.(2007). Resolution of inflammation: state of the art, definitions and terms. FASEB J vol. 21, (2) 325-332.
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Getting SJ, Lam CW, Leoni G, Gavins FNE, Grieco P, Perretti M(2006). [D-Trp(8)]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse). MOL PHARMACOL vol. 70, (6) 1850-1855.
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Sawmynaden P, Perretti M(2006). Glucocorticoid upregulation of the annexin-A1 receptor in leukocytes. Biochem Biophys Res Commun vol. 349, (4) 1351-1355.
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Getting SJ, Lam CW, Chen AS, Grieco P, Perretti M(2006). Melanocortin 3 receptors control crystal-induced inflammation. FASEB J vol. 20, (13) 2234-2241.
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Kamal AM, Hayhoe RPG, Paramasivam A, Cooper D, Flower RJ, Solito E, Perretti M(2006). Antiflammin-2 activates the human formyl-peptide receptor like 1. ScientificWorldJournal vol. 6, 1375-1384.
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Flower RJ, Ayoub S, Perretti M(2006). Anti-inflammatory and analgesic aspects of the annexin A1 system. ACTA PHARMACOL SIN vol. 27, (9) 1272-1272.
Cassatella MA, Perretti M(2006). Immunomodulation. The promises of immunopharmacology for the development of new drugs. Current Opinion in Pharmacology vol. 6, (4) 376-378.
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Flower RJ, Perretti M, D'Acquisto F, Buckingham JC(2006). Annexin 1, anti-inflammatory drugs and the neuroendocrine-immune interface. ACTA PHARMACOL SIN vol. 27, 13-14.
Yona S, Heinsbroek SEM, Peiser L, Gordon S, Perretti M, Flower RJ(2006). Impaired phagocytic mechanism in annexin 1 null macrophages. BRIT J PHARMACOL vol. 148, (4) 469-477.
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Gil CD, La M, Perretti M, Oliani SM(2006). Interaction of human neutrophils with endothelial cells regulates the expression of endogenous proteins annexin 1, galectin-1 and galectin-3. CELL BIOL INT vol. 30, (4) 338-344.
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Perretti M, D'Acquisto F(2006). Novel aspects of annexin 1 and glucocorticoid biology: intersection with nitric oxide and the lipoxin receptor. Inflamm Allergy Drug Targets vol. 5, (2) 107-114.
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Damazo AS, Yona S, Flower RJ, Perretti M, Oliani SM(2006). Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis. J IMMUNOL vol. 176, (7) 4410-4418.
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D'Acquisto F, Merghani A, Lecona E, Guglielmo R, Vo P, Raza K, Buckley C, Flower RJ et al. (2006). Annexin A1: a novel target of the immunosuppressive effects of glucocorticoids in autoimmune diseases. FASEB JOURNAL. vol. 20, A1376-A1376.
Babbin BA, Lee W, Winfree LM, Akyildiz A, Parkos CA, Perretti M, Nusrat A (2006). Annexin I regulates epithelial cell migration by signaling through formyl peptide receptors. FASEB JOURNAL. vol. 20, A1093-A1093.
Urquhart P, Cooper D, Motterlini R, Perretti M (2006). CO-releasing molecules modulate leukocyte/endothelial cell adhesion: under static and flow studies. FASEB JOURNAL. vol. 20, A1321-A1321.
Vong L, D'Acquisto F, Flower RJ, Witko-Sarsat V, Perretti M (2006). Cleavage of Annexin-A1 by proteinase 3: a possible cause of Wegener's vasculitis?. FASEB JOURNAL. vol. 20, A645-A645.
Renshaw D, Dalli J, Kamal A, Perretti M (2006). Disinct patterns of gene expression induced by annexin 1 activation of the ALXR receptor in HEK293 cells. FASEB JOURNAL. vol. 20, A646-A646.
Norling LV, Cooper D, Perretti M (2006). Endogenous Galectn-1 inhibits lymphocyte-endothelial cell interactions as determined by small interference RNA. FASEB JOURNAL. vol. 20, A647-A647.
Renshaw D, Sawmynadan P, Dalli J, Perretti M (2006). Glucocorticoid regulated expression of the anti-inflammatory receptor ALXR. FASEB JOURNAL. Conference: Experimental Biology 2006 Meeting (San Francisco, CA) from: 01/04/2006 to: 05/04/2006, vol. 20, A645-A645.
Duchene J, Lecomte F, Perretti M, Ahluwalia A (2006). Inflammatory chemokine CXCL5 expression by endothelial cells is dependent upon kinin B1 receptor activation. FASEB JOURNAL. vol. 20, A702-A702.
Hayhoe RPG, Cooper D, Perretti M (2006). The anti-adhesive effects of Annexin 1 on neutrophil-endothelial interactions under flow. FASEB JOURNAL. vol. 20, A646-A646.
Hayhoe RPG, Kamal AM, Solito E, Flower RJ, Cooper D, Perretti M(2006). Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement. BLOOD vol. 107, (5) 2123-2130.
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Getting SJ, Di Filippo C, D'Amico M, Perretti M(2006). The melanocortin peptide HP228 displays protective effects in acute models of inflammation and organ damage. EUR J PHARMACOL vol. 532, (1-2) 138-144.
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Lam CW, Perretti M, Getting SJ(2006). Melanocortin receptor signaling in RAW264.7 macrophage cell line. Peptides vol. 27, (2) 404-412.
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Perretti M, GETTING SJ, Spina D, Riffo-Vasquez Y, Page C, Pitchford S, Grieco P (2006). A role for MC3R in modulating eosinophil migration in allergic inflammation. Am J Pathol.
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Allegra M, Tesoriere L, D'acquisto F, Perretti M, Livrea M (2006). Indicaxanthin and betanin suppress LPS-induced NF-kappa B activation and modulate the levels of inflammatory mediators iNOS, COX-2 and PGE2 in macrophages. FREE RADICAL RESEARCH. vol. 40, S113-S113.
Perretti M, COOPER D, Gil CD, Oliani SM, Rosignoli G(2006). Inflammation-induced modulation of cellular galectin-1 and –3 expression in a model of rat peritonitis. inflammation Research vol. 55, (3) 99-107.
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Renshaw D, Urquhart P, Perretti M(2006). Therapeutic exploitation of endogenous anti-inflammatory mechanisms: Old and new leads. Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry vol. 5, (4) 289-305.
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Moraes LA, Paul-Clark MJ, Rickman A, Flower RJ, Goulding NJ, Perretti M(2005). Ligand-specific glucocorticoid receptor activation in human platelets. Blood vol. 106, (13) 4167-4175.
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Bensalem N, Ventura AP, Vallee B, Lipecka J, Tondelier D, Davezac N, Dos Santos A, Perretti M et al.(2005). Down-regulation of the anti-inflammatory protein annexin A1 in cystic fibrosis knock-out mice and patients. MOL CELL PROTEOMICS vol. 4, (10) 1591-1601.
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Gavins FNE, Sawmynaden P, Chatterjee BE, Perretti M(2005). A twist in anti-inflammation: annexin 1 acts via the lipoxin A4 receptor. Prostaglandins Leukot Essent Fatty Acids vol. 73, (3-4) 211-219.
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Chatterjee BE, Yona S, Rosignoli G, Young RE, Nourshargh S, Flower RJ, Perretti M(2005). Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro. J Leukoc Biol vol. 78, (3) 639-646.
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MacIntyre I, Mancini L, Perretti M (2005). Calcitonin abolishes collagen-induced arthritis. JOURNAL OF BONE AND MINERAL RESEARCH. vol. 20, S198-S199.
Yona S, Heinsbroek S, Gordon S, Perretti M, Flower RJ(2005). A novel role for Annexin 1 in macrophage phagocytosis. INFLAMM RES vol. 54, S217-S218.
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Getting SJ, Lam CW, Christian HC, Gavins FNE, Flower RJ, Schioth HB, Perretti M (2003). Melanocortin agonists possess anti-inflammatory effects in mice with a non-functional MC1-R (recessive yellow e/e). BRITISH JOURNAL OF PHARMACOLOGY. vol. 138, U6-U6.
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Getting SJ, Perretti M(2001). Arthritic diseases: melanocortin type 3 receptor agonists as potential therapeutics. Curr Opin Investig Drugs vol. 2, (8) 1064-1069.
Henderson RB, Lim LHK, Tessier PA, Gavins FNE, Mathies M, Perretti M, Hogg N(2001). The use of lymphocyte function-associated antigen (LFA)-1-deficient mice to determine the role of LFA-1, Mac-1, and alpha 4 integrin in the inflammatory response of neutrophils. J EXP MED vol. 194, (2) 219-226.
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Perretti M, Getting SJ, Solito E, Murphy PM, Gao JL(2001). Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics. AM J PATHOL vol. 158, (6) 1969-1973.
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Diaz B, Barreto E, Cordeiro R, Perretti M, Martins M, Silva P(2001). Enhanced serum glucocorticoid levels mediate the reduction of serosal mast cell numbers in diabetic rats. LIFE SCI vol. 68, (26) 2925-2932.
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La M, Bandiera S, Flower RJ, Perretti M (2001). Annexin-1-derived peptides protect against myocardial ischaemia reperfusion injury. BRIT J PHARMACOL. vol. 133, U20-U20.
Calatayud S, Allcock GH, Perretti M, Mitchell JA, Warner TD (2001). Comparison of the effects of the selective COX-2 inhibitor, DFP, and indomethacin on leukocyte-endothelial cell interactions in the rat mesentery. BRIT J PHARMACOL. vol. 133, U102-U102.
Getting SJ, Flower RJ, Perretti M (2001). Effect of melanocortin agonists on joint inflammation. BRIT J PHARMACOL. vol. 133, U19-U19.
Mancini L, MacIntyre I, Perretti M (2001). Glucocorticoids modulate osteoprotegerin/osteoprotegerin ligand and osteoclast activity. BONE. vol. 28, S161-S162.
Perretti M, Wheller SK, Getting SJ, Gao JL (2001). Involvement of FPR in the anti-inflammatory action of annexin-1. BRIT J PHARMACOL. vol. 133, U105-U105.
Goulding NJ, Rajakulendran S, Goulding PN, Perretti M, Flower RJ, Guyre PM (2001). Monocyte CD163 expression is regulated by glucocorticoids and lipopolysaccharide but not by chemokines. BRIT J PHARMACOL. vol. 133, U100-U100.
Solito E, de Coupade C, Canaider S, Goulding NJ, Perretti M(2001). Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation. BRIT J PHARMACOL vol. 133, (2) 217-228.
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Blades MC, Ingegnoli F, Manzo A, Wahid S, Haskard D, Panayi G, Perretti M, Pitzalis C(2001). Development of a new model to investigate lymphocyte migration into human peripheral lymph nodes (HPLN) transplanted into SCID mice. RHEUMATOLOGY vol. 40, 66-66.
Mabley J, Virag L, Jagtap P, Szabo E, Prendergast R, Perretti M, Getting S, Szabo C (2001). Effect of a novel poly (ADP-ribose) polymerase (PARP) inhibitor in rodent models of local inflammation. FASEB J. vol. 15, A242-A242.
Perretti M, Wheller SK, Getting SJ, Gao JL (2001). Interaction with the formylated receptor (FPR) is at the basis of annexin 1 anti-inflammatory effects. FASEB J. vol. 15, A681-A681.
Oliani SM, Paul-Clark MJ, Christian HC, Flower RJ, Perretti M(2001). Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression. AM J PATHOL vol. 158, (2) 603-615.
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Oliani SM, Perretti M (2001). Cell localization of the anti-inflammatory protein annexin 1 during experimental inflammatory response. Ital J Anat Embryol. vol. 106, 69-77.
PERRETTI M, Solito E, Russo-Marie F, de Coupade C, Ajuebor MN(2001). Cytokine modulation of liver annexin 1 expression during experimental endotoxemia. AM J PATHOL vol. 159, 1435-1443.
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PERRETTI M, Obinger C, Furtmuller PG, Allegra M, Regelsberger G, Livrea MA, Tesoriere L, Turco-Leveri ML(2001). Mechanism of Reaction of Melatonin with Human Myeloperoxidase. Biochem Biophys Res commun. vol. 282, 380-386.
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Oliani SM, Lim LHK, Christian HC, Pell K, Das AM, Perretti M(2001). Morphological alteration of peritoneal mast cells and macrophages in the mouse peritoneal cavity during the early phases of an allergic inflammatory reaction. CELL BIOL INT vol. 25, (8) 795-803.
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Getting SJ, Allcock GH, Flower R, Perretti M(2001). Natural and synthetic agonists of the melanocortin receptor type 3 possess anti-inflammatory properties. J Leukoc Biol vol. 69, (1) 98-104.
Allcock GH, Allegra M, Flower RJ, Perretti M(2001). Neutrophil accumulation induced by bacterial lipopolysaccharide: effects of dexamethasone and annexin 1. CLIN EXP IMMUNOL vol. 123, (1) 62-67.
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Mancini L, Moradi-Bidhendi N, Brandi ML, Perretti M, MacIntyre I(2000). Modulation of the effects of osteoprotegerin (OPG) ligand in a human leukemic cell line by OPG and calcitonin. BIOCHEM BIOPH RES CO vol. 279, (2) 391-397.
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Paul-Clark M, Del Soldato P, Fiorucci S, Flower RJ, Perretti M(2000). 21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties. Br J Pharmacol vol. 131, (7) 1345-1354.
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Mancini L, MacIntyre L, Brandi ML, Perretti M (2000). Analysis of osteoprotegerin ligand effects on the FLG 29.1 pre-osteoclastic cell line. BRIT J PHARMACOL. vol. 131, U15-U15.
Carollo M, Christie MI, Perretti M (2000). Expression of MIP-2, KC and MCR-1 and their receptors in chronic granulomatous inflammation. BRIT J PHARMACOL. vol. 131, U13-U13.
McLean PG, Perretti M, Ahluwalia A(2000). Kinin B(1) receptors and the cardiovascular system: regulation of expression and function. Cardiovasc Res vol. 48, (2) 194-210.
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D'Amico M, Di Filippo C, La M, Solito E, McLean PG, Flower RJ, Oliani SM, Perretti M(2000). Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment. FASEB J vol. 14, (13) 1867-1869.
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Oliani SM, Christian HC, Manston J, Flower RJ, Perretti M(2000). An immunocytochemical and in situ hybridization analysis of annexin 1 expression in rat mast cells: modulation by inflammation and dexamethasone. Lab Invest vol. 80, (9) 1429-1438.
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McLean PG, Ahluwalia A, Perretti M(2000). Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules. J Exp Med vol. 192, (3) 367-380.
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Perretti M, Page CP(2000). Heparin and inflammation: a new use for an old GAG?. Gut vol. 47, (1) 14-15.
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Lim LH, Flower RJ, Perretti M, Das AM(2000). Glucocorticoid receptor activation reduces CD11b and CD49d levels on murine eosinophils: characterization and functional relevance. Am J Respir Cell Mol Biol vol. 22, (6) 693-701.
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Perretti M, Ahluwalia A(2000). The microcirculation and inflammation: site of action for glucocorticoids. Microcirculation vol. 7, (3) 147-161.
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Getting SJ, Perretti M(2000). MC3-R as a novel target for antiinflammatory therapy. Drug News and Perspectives vol. 13, (1) 19-27.
McLean PG, Perretti M, Ahluwalia A(2000). Kinin B<inf>1</inf> receptors as novel anti-inflammatory targets. Expert Opinion on Therapeutic Targets vol. 4, (2) 127-141.
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Canaider S, Solito E, de Coupade C, Flower RJ, Russo-Marie F, Goulding NJ, Perretti M(2000). Increased apoptosis in U937 cells over-expressing lipocortin 1 (annexin I). Life Sci vol. 66, (18) PL265-PL270.
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Perretti M, Christian H, Wheller SK, Aiello I, Mugridge KG, Morris JF, Flower RJ, Goulding NJ(2000). Annexin I is stored within gelatinase granules of human neutrophil and mobilized on the cell surface upon adhesion but not phagocytosis. Cell Biol Int vol. 24, (3) 163-174.
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Getting SJ, Flower RJ, Perretti M (1999). Agonism at melanocortin receptor type 3 on macrophages inhibits neutrophil influx. Inflammation Research. vol. 48,
Tailor A, Tomlinson A, Salas A, Panés J, Granger DN, Flower RJ, Perretti M(1999). Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC. Gut vol. 45, (5) 705-712.
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McLean PG, Perretti M, Ahluwalia A(1999). Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des-Arg9bradykinin-induced coronary vasodilation. Br J Pharmacol vol. 128, (2) 275-282.
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Das AM, Ajuebor MN, Flower RJ, Perretti M, McColl SR(1999). Contrasting roles for RANTES and macrophage inflammatory protein-1 alpha (MIP-1 alpha) in a murine model of allergic peritonitis. Clin Exp Immunol vol. 117, (2) 223-229.
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Getting SJ, Gibbs L, Clark AJ, Flower RJ, Perretti M(1999). POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. J Immunol vol. 162, (12) 7446-7453.
Perretti M, Wheller SK, Flower RJ, Wahid S, Pitzalis C(1999). Modulation of cellular annexin I in human leukocytes infiltrating DTH skin reactions. J Leukoc Biol vol. 65, (5) 583-589.
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Ahluwalia A, Perretti M(1999). B1 receptors as a new inflammatory target. Could this B the 1?. Trends Pharmacol Sci vol. 20, (3) 100-104.
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Minghetti L, Nicolini A, Polazzi E, Greco A, Perretti M, Parente L, Levi G(1999). Down-regulation of microglial cyclo-oxygenase-2 and inducible nitric oxide synthase expression by lipocortin 1. Br J Pharmacol vol. 126, (6) 1307-1314.
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Ajuebor MN, Das AM, Virág L, Szabó C, Perretti M(1999). Regulation of macrophage inflammatory protein-1 alpha expression and function by endogenous interleukin-10 in a model of acute inflammation. Biochem Biophys Res Commun vol. 255, (2) 279-282.
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Ajuebor MN, Das AM, Virág L, Flower RJ, Szabó C, Perretti M(1999). Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. J Immunol vol. 162, (3) 1685-1691.
Euzger HS, Flower RJ, Goulding NJ, Perretti M(1999). Differential modulation of annexin I binding sites on monocytes and neutrophils. Mediators Inflamm vol. 8, (1) 53-62.
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Ruetten H, Thiemermann C, Perretti M(1999). Upregulation of ICAM-1 expression on J774.2 macrophages by endotoxin involves activation of NF-kappaB but not protein tyrosine kinase: comparison to induction of iNOS. Mediators Inflamm vol. 8, (2) 77-84.
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Ajuebor MN, Virág L, Flower RJ, Perretti M, Szabó C(1998). Role of inducible nitric oxide synthase in the regulation of neutrophil migration in zymosan-induced inflammation. Immunology vol. 95, (4) 625-630.
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Lim LH, Solito E, Russo-Marie F, Flower RJ, Perretti M(1998). Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1. Proc Natl Acad Sci U S A vol. 95, (24) 14535-14539.
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Perretti M(1998). Lipocortin 1 and chemokine modulation of granulocyte and monocyte accumulation in experimental inflammation. Gen Pharmacol vol. 31, (4) 545-552.
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Goulding NJ, Euzger HS, Butt SK, Perretti M (1998). Novel pathways for glucocorticoid effects on neutrophils in chronic inflammation. Inflamm Res. vol. 47 Suppl 3, S158-S165.
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Ajuebor MN, Gibbs L, Flower RJ, Das AM, Perretti M(1998). Investigation of the functional role played by the chemokine monocyte chemoattractant protein-1 in interleukin-1-induced murine peritonitis. Br J Pharmacol vol. 125, (2) 319-326.
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Das AM, Flower RJ, Perretti M(1998). Resident mast cells are important for eotaxin-induced eosinophil accumulation in vivo. J Leukoc Biol vol. 64, (2) 156-162.
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Ahluwalia A, De Felipe C, O'Brien J, Hunt SP, Perretti M(1998). Impaired IL-1beta-induced neutrophil accumulation in tachykinin NK1 receptor knockout mice. Br J Pharmacol vol. 124, (6) 1013-1015.
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Pistritto G, Mancuso C, Tringali G, Perretti M, Preziosi P, Navarra P(1998). The relative contribution of constitutive and inducible cyclooxygenase activity to lipopolysaccharide-induced prostaglandin production by primary cultures of rat hypothalamic astrocytes. Neurosci Lett vol. 246, (1) 45-48.
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Bryant CE, Perretti M, Flower RJ(1998). Suppression by dexamethasone of inducible nitric oxide synthase protein expression in vivo: a possible role for lipocortin 1. Biochem Pharmacol vol. 55, (3) 279-285.
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Teixeira MM, Das AM, Miotla JM, Perretti M, Hellewell PG(1998). The role of lipocortin-1 in the inhibitory action of dexamethasone on eosinophil trafficking in cutaneous inflammatory reactions in the mouse. Br J Pharmacol vol. 123, (3) 538-544.
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Ajuebor MN, Flower RJ, Hannon R, Christie M, Bowers K, Verity A, Perretti M(1998). Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model. J Leukoc Biol vol. 63, (1) 108-116.
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Cuzzocrea S, Tailor A, Zingarelli B, Salzman AL, Flower RJ, Szabó C, Perretti M(1997). Lipocortin 1 protects against splanchnic artery occlusion and reperfusion injury by affecting neutrophil migration. J Immunol vol. 159, (10) 5089-5097.
Perretti M(1997). Endogenous mediators that inhibit the leukocyte-endothelium interaction. Trends Pharmacol Sci vol. 18, (11) 418-425.
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Szabó C, Lim LH, Cuzzocrea S, Getting SJ, Zingarelli B, Flower RJ, Salzman AL, Perretti M(1997). Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. J Exp Med vol. 186, (7) 1041-1049.
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Getting SJ, Flower RJ, Parente L, de Medicis R, Lussier A, Woliztky BA, Martins MA, Perretti M(1997). Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins. J Pharmacol Exp Ther vol. 283, (1) 123-130.
Tailor A, Flower RJ, Perretti M(1997). Dexamethasone inhibits leukocyte emigration in rat mesenteric post-capillary venules: an intravital microscopy study. J Leukoc Biol vol. 62, (3) 301-308.
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Das AM, Flower RJ, Perretti M(1997). Eotaxin-induced eosinophil migration in the peritoneal cavity of ovalbumin-sensitized mice: mechanism of action. J Immunol vol. 159, (3) 1466-1473.
Wheller SK, Perretti M(1997). Dexamethasone inhibits cytokine-induced intercellular adhesion molecule-1 up-regulation on endothelial cell lines. Eur J Pharmacol vol. 331, (1) 65-71.
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Ferreira SH, Cunha FQ, Lorenzetti BB, Michelin MA, Perretti M, Flower RJ, Poole S(1997). Role of lipocortin-1 in the anti-hyperalgesic actions of dexamethasone. Br J Pharmacol vol. 121, (5) 883-888.
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Das AM, Flower RJ, Hellewell PG, Teixeira MM, Perretti M(1997). A novel murine model of allergic inflammation to study the effect of dexamethasone on eosinophil recruitment. Br J Pharmacol vol. 121, (1) 97-104.
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Getting SJ, Flower RJ, Perretti M(1997). Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. Br J Pharmacol vol. 120, (6) 1075-1082.
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Tailor A, Das AM, Getting SJ, Flower RJ, Perretti M(1997). Subacute treatment of rats with dexamethasone reduces ICAM-1 levels on circulating monocytes. Biochem Biophys Res Commun vol. 231, (3) 675-678.
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Das AM, Lim LH, Flower RJ, Perretti M(1997). Dexamethasone reduces cell surface levels of CD11b on human eosinophils. Mediators Inflamm vol. 6, (5-6) 363-367.
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Perretti M, Croxtall JD, Wheller SK, Goulding NJ, Hannon R, Flower RJ(1996). Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration. Nat Med vol. 2, (11) 1259-1262.
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Perretti M, Wheller SK, Harris JG, Flower RJ(1996). Modulation of ICAM-1 levels on U-937 cells and mouse macrophages by interleukin-1 beta and dexamethasone. Biochem Biophys Res Commun vol. 223, (1) 112-117.
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Perretti M, Flower RJ(1996). Measurement of lipocortin 1 levels in murine peripheral blood leukocytes by flow cytometry: modulation by glucocorticoids and inflammation. Br J Pharmacol vol. 118, (3) 605-610.
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Harris JG, Flower RJ, Watanabe K, Tsurufuji S, Wolitzky BA, Perretti M(1996). Relative contribution of the selectins in the neutrophil recruitment caused by the chemokine cytokine-induced neutrophil chemoattractant (CINC). Biochem Biophys Res Commun vol. 221, (3) 692-696.
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Malcangio M, Bowery NG, Flower RJ, Perretti M(1996). Effect of interleukin-1 beta on the release of substance P from rat isolated spinal cord. Eur J Pharmacol vol. 299, (1-3) 113-118.
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Perretti M, Ahluwalia A, Harris JG, Harris HJ, Wheller SK, Flower RJ(1996). Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1. Br J Pharmacol vol. 117, (6) 1145-1154.
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Harris JG, Flower RJ, Watanabe K, Tsurufuji S, Wolitzky BA, Perretti M(1996). Erratum: Relative contribution of the selectins in the neutrophil recruitment caused by the chemokine cytokine-induced neutrophil chemoattractant (CINC) (Biochemical and Biophysical Research Communications (1996) 221 3 (692-696)). Biochemical and Biophysical Research Communications vol. 224, (3) 878-879.
Ahluwalia A, Perretti M(1996). Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse. J Immunol vol. 156, (1) 269-274.
Mugridge KG, Perretti M, Ghiara P, Galeotti CL, Melli M, Parente L(1995). Gastric antisecretory and anti-ulcer actions of IL-1 in rat involve different IL-1 receptor types. Am J Physiol vol. 269, (5 Pt 1) G763-G769.
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Perretti M, Szabó C, Thiemermann C(1995). Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse. Br J Pharmacol vol. 116, (4) 2251-2257.
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Perretti M, Wheller SK, Choudhury Q, Croxtall JD, Flower RJ(1995). Selective inhibition of neutrophil function by a peptide derived from lipocortin 1 N-terminus. Biochem Pharmacol vol. 50, (7) 1037-1042.
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Harris JG, Flower RJ, Perretti M(1995). Endogenous corticosteroids mediate the neutrophilia caused by platelet-activating factor in the mouse. Eur J Pharmacol vol. 283, (1-3) 9-18.
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Klemm P, Harris HJ, Perretti M(1995). Effect of rolipram in a murine model of acute inflammation: comparison with the corticoid dexamethasone. Eur J Pharmacol vol. 281, (1) 69-74.
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Palmi M, Frosini M, Sgaragli GP, Becherucci C, Perretti M, Parente L(1995). Inhibition of interleukin-1 beta-induced pyresis in the rabbit by peptide 204-212 of lipocortin 5. Eur J Pharmacol vol. 281, (1) 97-99.
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Mancuso F, Flower RJ, Perretti M(1995). Leukocyte transmigration, but not rolling or adhesion, is selectively inhibited by dexamethasone in the hamster post-capillary venule. Involvement of endogenous lipocortin 1. J Immunol vol. 155, (1) 377-386.
Harris JG, Flower RJ, Perretti M(1995). Alteration of neutrophil trafficking by a lipocortin 1 N-terminus peptide. Eur J Pharmacol vol. 279, (2-3) 149-157.
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Wu CC, Croxtall JD, Perretti M, Bryant CE, Thiemermann C, Flower RJ, Vane JR(1995). Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proc Natl Acad Sci U S A vol. 92, (8) 3473-3477.
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Perretti M, Flower RJ (1995). Anti-inflammatory lipocortin-derived peptides. Agents Actions Suppl. vol. 46, 131-138.
Ahluwalia A, Perretti M(1994). Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse. Eur J Pharmacol vol. 264, (3) 407-415.
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Perretti M, Harris JG, Flower RJ(1994). A role for endogenous histamine in interleukin-8-induced neutrophil infiltration into mouse air-pouch: investigation of the modulatory action of systemic and local dexamethasone. Br J Pharmacol vol. 112, (3) 801-808.
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Perretti M, Flower RJ(1994). Cytokines, glucocorticoids and lipocortins in the control of neutrophil migration. Pharmacol Res vol. 30, (1) 53-59.
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Perretti M(1994). Lipocortin-derived peptides. Biochem Pharmacol vol. 47, (6) 931-938.
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Ahluwalia A, Perretti M(1994). Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors. J Pharmacol Exp Ther vol. 268, (3) 1526-1531.
Szabó C, Thiemermann C, Wu CC, Perretti M, Vane JR(1994). Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. Proc Natl Acad Sci U S A vol. 91, (1) 271-275.
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Perretti M, Ahluwalia A, Harris JG, Goulding NJ, Flower RJ(1993). Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody. J Immunol vol. 151, (8) 4306-4314.
Perretti M, Duncan GS, Flower RJ, Peers SH(1993). Serum corticosterone, interleukin-1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar strains. Br J Pharmacol vol. 110, (2) 868-874.
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Perretti M, Ahluwalia A, Flower RJ, Manzini S(1993). Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors. Immunology vol. 80, (1) 73-77.
Thiemermann C, Wu CC, Szabó C, Perretti M, Vane JR(1993). Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock. Br J Pharmacol vol. 110, (1) 177-182.
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Perretti M, Flower RJ, Goulding NJ(1993). The ability of murine leukocytes to bind lipocortin 1 is lost during acute inflammation. Biochem Biophys Res Commun vol. 192, (2) 345-350.
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Cirino G, Cicala C, Sorrentino L, Ciliberto G, Arpaia G, Perretti M, Flower RJ(1993). Anti-inflammatory actions of an N-terminal peptide from human lipocortin 1. Br J Pharmacol vol. 108, (3) 573-574.
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Da Silva JA, Peers SH, Perretti M, Willoughby DA(1993). Sex steroids affect glucocorticoid response to chronic inflammation and to interleukin-1. J Endocrinol vol. 136, (3) 389-397.
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Croxtall J, Flower R, Perretti M (1993). The role of lipocortin 1 in the regulation of A549 cell proliferation and leukocyte migration. J Lipid Mediat. vol. 6, 295-302.
Perretti M, Flower RJ(1993). Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1. J Immunol vol. 150, (3) 992-999.
Becherucci C, Perretti M, Solito E, Galeotti CL, Parente L(1993). Conceivable difference in the anti-inflammatory mechanisms of lipocortins 1 and 5. Mediators Inflamm vol. 2, (2) 109-113.
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Becherucci C, Parente L, Perretti M, Mugridge KG(1993). Inhibition of smooth muscle contraction and platelet aggregation by peptide 204-212 of lipocortin 5: an attempt to define some structure requirements. Mediators of Inflammation vol. 2, (2) 103-107.
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Perretti M, Appleton I, Parente L, Flower RJ (1993). Pharmacology of interleukin-1-induced neutrophil migration. Agents Actions. vol. 38 Spec No, C64-C65.
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Douglas GJ, Flower RJ, Parente L, Perretti M(1992). Peptide 204-212 of lipocortin 5 inhibits the generation of a prostacyclin-like factor from rat aorta preparations in vitro. Prostaglandins vol. 44, (5) 381-388.
10.1016/0090-6980(92)90134-F
Parente L, Perretti M, Wallace JL, Mugridge KG(1992). Mechanism of the protective action of interleukin-1 in the experimental gastric damage in the rat. Pharmacol Res vol. 26 Suppl 2, 28-29.
10.1016/1043-6618(92)90584-X
Perretti M, Mugridge KG, Wallace JL, Parente L(1992). Reduction of aspirin-induced gastric damage in rats by interleukin-1 beta: possible involvement of endogenous corticosteroids. J Pharmacol Exp Ther vol. 261, (3) 1238-1247.
Becherucci C, Perretti M, Nencioni L, Silvestri S, Parente L(1992). Anti-inflammatory effect of tuftsin and its retro-inverso analogue in rat adjuvant arthritis. Agents Actions vol. Spec No, C115-C117.
10.1007/BF01991043
Perretti M, Solito E, Parente L(1992). Evidence that endogenous interleukin-1 is involved in leukocyte migration in acute experimental inflammation in rats and mice. Agents Actions vol. 35, (1-2) 71-78.
10.1007/BF01990954
Verdini AS, Silvestri S, Becherucci C, Longobardi MG, Parente L, Peppoloni S, Perretti M, Pileri P et al.(1991). Immunostimulation by a partially modified retro-inverso-tuftsin analogue containing Thr1 psi[NHCO](R,S)Lys2 modification. J Med Chem vol. 34, (12) 3372-3379.
10.1021/jm00116a005
Perretti M, Mugridge KG, Becherucci C, Parente L(1991). Evidence that interleukin-1 and lipoxygenase metabolites mediate the lethal effect of complete Freund's adjuvant in adrenalectomized rats. Lymphokine Cytokine Res vol. 10, (4) 239-243.
Perretti M, Becherucci C, Mugridge KG, Solito E, Silvestri S, Parente L(1991). A novel anti-inflammatory peptide from human lipocortin 5. Br J Pharmacol vol. 103, (2) 1327-1332.
10.1111/j.1476-5381.1991.tb09788.x
Mugridge KG, Perretti M, Ghiara P, Parente L(1991). Alpha-melanocyte-stimulating hormone reduces interleukin-1 beta effects on rat stomach preparations possibly through interference with a type I receptor. Eur J Pharmacol vol. 197, (2-3) 151-155.
10.1016/0014-2999(91)90514-Q
Dal Piaz V, Ciciani G, Turco G, Giovannoni MP, Miceli M, Pirisino R, Perretti M(1991). 5-Acyl-6-aryl-4-nitro-3(2H)pyridazinones and related 4-amino compounds: synthesis and pharmacological evaluation. J Pharm Sci vol. 80, (4) 341-348.
10.1002/jps.2600800412
Mugridge KG, Perretti M, Parente L(1991). 5-Lipoxygenase activation may facilitate an interleukin-1 transduction signal. Adv Prostaglandin Thromboxane Leukot Res vol. 21B, 517-520.
Mugridge KG, Perretti M, Becherucci C, Parente L(1991). Persistent effects of interleukin-1 on smooth muscle preparations from adrenalectomized rats: implications for increased phospholipase-A2 activity via stimulation of 5-lipoxygenase. J Pharmacol Exp Ther vol. 256, (1) 29-37.
Becherucci C, Solito E, Perretti M, Mugridge KG, Galeotti CL, Parente L(1990). Purification and biological activity of human lipocortin 2. Pharmacol Res vol. 22 Suppl 1, 29-30.
10.1016/1043-6618(90)90792-C
Perretti M, Nuti S, Parente L(1990). Investigation of rat mast cell degranulation using flow cytometry. J Pharmacol Methods vol. 23, (3) 187-194.
10.1016/0160-5402(90)90062-P
Perretti M, Mugridge KG, Becherucci C, Silvestri S, Parente L(1990). Antiulcer property of human recombinant interleukin-1β. Pharmacological Research vol. 22,
10.1016/1043-6618(90)90427-F
Parente L, Becherucci C, Perretti M, Solito E, Mugridge KG, Galeotti CL, Raugei G, Melli M et al.(1990). Are the lipocortins the second messengers of the anti-inflammatory action of glucocorticoids?. Prog Clin Biol Res vol. 349, 55-68.
Becherucci C, Perretti M, Galeotti C, Parente L(1990). Different anti-inflammatory effects of lipocortins 1 and 5. Pharmacological Research vol. 22,
10.1016/S1043-6618(09)80089-3
Parente L, Mugridge KG, Perretti M, Solito E(1990). In vitro and in vivo activation of phospholipase A<inf>2</inf> by interleukin-1. Pharmacological Research vol. 22,
10.1016/1043-6618(90)90413-8
Perretti M, Becherucci C, Scapigliati G, Parente L(1989). The effect of adrenalectomy on interleukin-1 release in vitro and in vivo. Br J Pharmacol vol. 98, (4) 1137-1142.
10.1111/j.1476-5381.1989.tb12657.x
Becherucci C, Donati D, Perretti M, Parente L(1989). The release of interleukin-1-like activity by macrophages in two models of immunological inflammation in the rat. Agents Actions vol. 28, (3-4) 243-247.
10.1007/BF01967410
Ignesti G, Perretti M, Buffoni F(1988). Induction and quail liver diamine oxidase (histaminase). Part I: Interference of spermidine synthase on the diamine oxidase activity assay using putrescine as substrate. Agents Actions vol. 25, (1-2) 37-42.
10.1007/BF01969091
Ignesti G, Buffoni F, Perretti M, Cintelli A(1988). Induction and quail liver diamine oxidase (histaminase). Part II: Different responses to the inducers. Agents Actions vol. 25, (1-2) 43-47.
10.1007/BF01969092
Perretti M, Becherucci C, Parente L(1988). Interleukin-1 release by macrophages from adrenalectomized (ADX) and shamoperated (SHO) rats. Pharmacological Research Communications vol. 20, (SUPPL. 2)
10.1016/S0031-6989(88)80429-6
Becherucci C, Donati D, Perretti M, Parente L(1988). Interleukin-1 release by rat macrophages in experimental immunological inflammation. Pharmacological Research Communications vol. 20, (SUPPL. 2)
10.1016/S0031-6989(88)80159-0
Ignesti G, Perretti M, Buffoni F(1986). Diamine oxidase activity in Japanese quail liver induced with aroclor 1254. Agents Actions vol. 18, (1-2) 41-43.
10.1007/BF01987977
Bombardieri G, Bevilacqua E, Conti LR, Innocenti P, Perretti MA(1981). Plasma amine oxidases in Wilson's disease. Life Sci vol. 29, (2) 117-120.
10.1016/0024-3205(81)90279-4
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