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Publications:  Prof Sussan Nourshargh

Kostelnik KB, Barker A, Schultz C, Mitchell TP, Rajeeve V, White IJ, Aurrand-Lions M, Nourshargh S et al.(2019). Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration. PLoS biology vol. 17, (12)
10.1371/journal.pbio.3000554
Arokiasamy S, King R, Boulaghrasse H, Poston R, Nourshargh S, Wang W, Voisin M-B(2019). Heparanase-dependent Remodelling of Initial Lymphatic Glycocalyx 1 Regulates Tissue-fluid Drainage during Acute Inflammation in vivo. Frontiers in Immunology
10.3389/fimmu.2019.02316
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60002
Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N et al.(2019). Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology vol. 49, (10) 1457-1973.
10.1002/eji.201970107
Voisin M-B, Nourshargh S(2019). Neutrophil trafficking to lymphoid tissues: physiological and pathological implications. J Pathol vol. 247, (5) 662-671.
10.1002/path.5227
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54509
VOISIN M, leoni G, WOODFIN A, loumagne L, PATEL N, Di Paola R, Cuzzocrea S, THIEMERMANN C et al.(2019). Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post ischemia/reperfusion injury. Journal of Pathology vol. 248, (1) 88-102.
10.1002/path.5234
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54857
Reglero-Real N, Rolas L, Nourshargh S(2019). Leukocyte Trafficking: Time to Take Time Seriously. Immunity vol. 50, (2) 273-275.
10.1016/j.immuni.2019.01.013
NOURSHARGH S, ROLAS L, BARKAWAY A(2019). Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome. Nature Medicine423-426.
10.1038/s41591-018-0338-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56282
GIRBL T, Lenn T, Perez L, ROLAS L, BARKAWAY A, Thiriot A, del Fresno C, Lynam E et al.(2018). Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the atypical receptor ACKR1 determine discrete stages of neutrophil diapedesis. Immunity
10.1016/j.immuni.2018.09.018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/50484
Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB et al.(2018). Correction: Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Med vol. 15, (10) e1002694-e1002694.
10.1371/journal.pmed.1002694
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58929
Cossarizza A, Chang H-D, Radbruch A, Akdis M, Andrä I, Annunziato F, Bacher P, Barnaba V et al.(2018). Guidelines for the use of flow cytometry and cell sorting in immunological studies. Eur J Immunol vol. 47, (10) 1584-1797.
10.1002/eji.201646632
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38563
Wen G, An W, Chen J, Maguire EM, Chen Q, Yang F, Pearce SWA, Kyriakides M et al.(2018). Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis. J Am Heart Assoc vol. 7, (4)
10.1161/JAHA.117.008187
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39046
Schulz-Fincke A-C, Tikhomirov AS, Braune A, Girbl T, Gilberg E, Bajorath J, Blaut M, Nourshargh S et al.(2018). Design of an Activity-Based Probe for Human Neutrophil Elastase: Implementation of the Lossen Rearrangement To Induce Förster Resonance Energy Transfers. Biochemistry vol. 57, (5) 742-752.
10.1021/acs.biochem.7b00906
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38565
Callender LA, carroll EC, beal R, Chambers ES, Nourshargh S, Akbar AN, Henson SM(2017). Human CD8+ EMRA T cells display a senescent-associated secretory phenotype regulated by p38 MAPK. Aging Cell
10.1111/acel.12675
https://qmro.qmul.ac.uk/xmlui/handle/123456789/26363
CABRERA CP, MANSON J, SHEPHERD JM, TORRANCE HD, WATSON D, LONGHI MP, HOTI M, PATEL MB et al.(2017). Signatures of Inflammation and Impending Multiple Organ Dysfunction in the Hyperacute Phase of Trauma. PLoS Medicine
10.1371/journal.pmed.1002352
https://qmro.qmul.ac.uk/xmlui/handle/123456789/26246
Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB et al.(2017). Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Medicine vol. 14, (7)
10.1371/journal.pmed.1002352
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25043
Gittens BR, Bodkin JV, Nourshargh S, Perretti M, Cooper D(2017). Galectin-3: A positive regulator of leukocyte recruitment in the inflamed microcirculation. Journal of Immunology vol. 198, (11) 4458-4469.
10.4049/jimmunol.1600709
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23167
VOISIN M(2017). Endogenous TNFα orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation. Scientific Reports
10.1038/srep44189
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23723
Barzilai S, Yadav SK, Morrell S, Roncato F, Klein E, Stoler-Barak L, Golani O, Feigelson SW et al.(2017). Leukocytes Breach Endothelial Barriers by Insertion of Nuclear Lobes and Disassembly of Endothelial Actin Filaments. Cell Rep vol. 18, (3) 685-699.
10.1016/j.celrep.2016.12.076
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18845
Herrera C, Voisin M-B, Escalante T, Rucavado A, Nourshargh S, Gutiérrez JM(2016). Effects of PI and PIII Snake Venom Haemorrhagic Metalloproteinases on the Microvasculature: A Confocal Microscopy Study on the Mouse Cremaster Muscle. PLoS One vol. 11, (12) Article 0168643, e0168643-e0168643.
10.1371/journal.pone.0168643
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18945
Reglero-Real N, Colom B, Bodkin JV, Nourshargh S(2016). Endothelial Cell Junctional Adhesion Molecules. Arteriosclerosis, Thrombosis and Vascular BiologyATVBAHA.116.307610-ATVBAHA.116.307610.
10.1161/ATVBAHA.116.307610
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15564
WHITEFORD J, Ma B, Woodfin, Nourshargh(2016). Underlying chronic inflammation alters the profile and mechanisms of acute neutrophil recruitment. Journal of Pathology
10.1002/path.4776
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15915
Nourshargh S, Renshaw SA, Imhof BA(2016). Reverse Migration of Neutrophils: Where, When, How, and Why?. Trends in immunology
10.1016/j.it.2016.03.006
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14983
Woodfin A, Beyrau M, Voisin M-B, Ma B, Whiteford JR, Hordijk PL, Hogg N, Nourshargh S(2016). ICAM-1-expressing neutrophils exhibit enhanced effector functions in murine models of endotoxemia. Blood vol. 127, (7) 898-907.
10.1182/blood-2015-08-664995
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13894
Madalli S, Beyrau M, Whiteford J, Duchene J, Nandhra IS, Patel NSA, Motwani MP, Gilroy DW et al.(2015). Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states. Biology of Sex Differences vol. 6, (1)
10.1186/s13293-015-0047-5
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12543
Yeh JSM, Sennoga CA, McConnell E, Eckersley R, Tang MX, Nourshargh S, Seddon JM, Haskard DO et al.(2015). Quantitative Ultrasound Molecular Imaging. Ultrasound in Medicine and Biology vol. 41, (9) 2478-2496.
10.1016/j.ultrasmedbio.2015.04.011
Armstrong PCJ, Kirkby NS, Chan MV, Finsterbusch M, Hogg N, Nourshargh S, Warner TD(2015). Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction. Blood vol. 126, (10) e11-e18.
10.1182/blood-2015-01-621656
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15669
Yeh JSM, Sennoga CA, McConnell E, Eckersley R, Tang MX, Nourshargh S, Seddon JM, Haskard DO et al.(2015). A targeting microbubble for ultrasound molecular imaging. PLoS ONE vol. 10, (7)
10.1371/journal.pone.0129681
Colom B, Bodkin JV, Beyrau M, Woodfin A, Ody C, Rourke C, Chavakis T, Brohi K et al.(2015). Leukotriene B<inf>4</inf>-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration InVivo. Immunity vol. 42, (6) 1075-1086.
10.1016/j.immuni.2015.05.010
Herrera C, Escalante T, Voisin M-B, Rucavado A, Morazán D, Macêdo JKA, Calvete JJ, Sanz L et al.(2015). Tissue localization and extracellular matrix degradation by PI, PII and PIII snake venom metalloproteinases: clues on the mechanisms of venom-induced hemorrhage. PLoS Negl Trop Dis vol. 9, (4)
10.1371/journal.pntd.0003731
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9775
Nourshargh S, Alon R(2014). Leukocyte migration into inflamed tissues. Immunity vol. 41, (5) 694-707.
10.1016/j.immuni.2014.10.008
De Rossi G, Evans AR, Kay E, Woodfin A, McKay TR, Nourshargh S, Whiteford JR(2014). Shed syndecan-2 inhibits angiogenesis. J Cell Sci vol. 127, (Pt 21) 4788-4799.
10.1242/jcs.153015
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11427
Finsterbusch M, Voisin M-B, Beyrau M, Williams TJ, Nourshargh S(2014). Neutrophils recruited by chemoattractants in vivo induce microvascular plasma protein leakage through secretion of TNF. J Exp Med vol. 211, (7) 1307-1314.
10.1084/jem.20132413
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13892
Colom B, Bodkin JV, Beyrau M, Woodfin A, Ody C, Rourke C, Chavakis T, Brohi K et al.(2014). Leukotriene B<inf>4</inf>-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration InVivo. Immunity
10.1016/j.immuni.2015.05.010
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13961
Halai K, Whiteford J, Ma B, Nourshargh S, Woodfin A(2014). ICAM-2 facilitates luminal interactions between neutrophils and endothelial cells in vivo. J Cell Sci vol. 127, (Pt 3) 620-629.
10.1242/jcs.137463
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13895
Leinster DA, Colom B, Whiteford JR, Ennis DP, Lockley M, McNeish IA, Aurrand-Lions M, Chavakis T et al.(2013). Endothelial cell junctional adhesion molecule C plays a key role in the development of tumors in a murine model of ovarian cancer. FASEB J vol. 27, (10) 4244-4253.
10.1096/fj.13-230441
Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S et al.(2013). A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation. Blood vol. 122, (4) 608-617.
10.1182/blood-2013-04-496661
Alazawi W, Heath H, Waters JA, Woodfin A, O'Brien AJ, Scarzello AJ, Ma B, Lopez-Otalora Y et al.(2013). Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis. Proc Natl Acad Sci U S A vol. 110, (21) 8656-8661.
10.1073/pnas.1221652110
Nourshargh S(2013). L2. Neutrophil transmigration in vivo: mechanisms, dynamics and contribution to dissemination of systemic inflammation. Presse Med vol. 42, (4 Pt 2) 498-499.
10.1016/j.lpm.2013.01.004
Alon R, Nourshargh S(2013). Learning in motion: pericytes instruct migrating innate leukocytes. Nat Immunol vol. 14, (1) 14-15.
10.1038/ni.2489
Voisin M-B, Nourshargh S(2013). Neutrophil transmigration: emergence of an adhesive cascade within venular walls. J Innate Immun vol. 5, (4) 336-347.
10.1159/000346659
Kishore M, Ma L, Cornish G, Nourshargh S, Marelli-Berg F (2012). Primed T Cell Responses to Chemokines Are Regulated by the Immunoglobulin-Like Molecule CD31. TRANSPLANTATION. vol. 94, 456-456.
10.1097/00007890-201211271-00869
Beyrau M, Bodkin JV, Nourshargh S(2012). Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity. Open Biol vol. 2, (11)
10.1098/rsob.120134
Ma L, Cheung KCP, Kishore M, Nourshargh S, Mauro C, Marelli-Berg FM(2012). CD31 exhibits multiple roles in regulating T lymphocyte trafficking in vivo. J Immunol vol. 189, (8) 4104-4111.
10.4049/jimmunol.1201739
Avari P, Huang W, Averill S, Colom B, Imhof BA, Nourshargh S, Priestley JV(2012). The spatiotemporal localization of JAM-C following sciatic nerve crush in adult rats. Brain Behav vol. 2, (4) 402-414.
10.1002/brb3.63
Proebstl D, Voisin M-B, Woodfin A, Whiteford J, D'Acquisto F, Jones GE, Rowe D, Nourshargh S(2012). Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med vol. 209, (6) 1219-1234.
10.1084/jem.20111622
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14750
Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FNE, Cooper D, Gould D et al.(2012). The peritoneal tumour microenvironment of high-grade serous ovarian cancer. J Pathol vol. 227, (2) 136-145.
10.1002/path.4002
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13856
Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD et al.(2012). Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves. FASEB J vol. 26, (3) 1064-1076.
10.1096/fj.11-196220
Kishore M, Ma L, Cornish G, Nourshargh S, Marelli-Berg FM(2012). Primed T cell responses to chemokines are regulated by the immunoglobulin-like molecule CD31. PLoS One vol. 7, (6)
10.1371/journal.pone.0039433
https://qmro.qmul.ac.uk/xmlui/handle/123456789/4879
Whiteford JR, Xian X, Chaussade C, Vanhaesebroeck B, Nourshargh S, Couchman JR(2011). Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148. Mol Biol Cell vol. 22, (19) 3609-3624.
10.1091/mbc.E11-02-0099
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14751
Woodfin A, Voisin M-B, Beyrau M, Colom B, Caille D, Diapouli F-M, Nash GB, Chavakis T et al.(2011). The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo. Nat Immunol vol. 12, (8) 761-769.
10.1038/ni.2062
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19663
Veninga H, de Groot DM, McCloskey N, Owens BM, Dessing MC, Verbeek JS, Nourshargh S, van Eenennaam H et al.(2011). CD97 antibody depletes granulocytes in mice under conditions of acute inflammation via a Fc receptor-dependent mechanism. J Leukoc Biol vol. 89, (3) 413-421.
10.1189/jlb.0510280
Ma L, Mauro C, Cornish GH, Chai J-G, Coe D, Fu H, Patton D, Okkenhaug K et al.(2010). Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance. Proc Natl Acad Sci U S A vol. 107, (45) 19461-19466.
10.1073/pnas.1011748107
Nourshargh S, Hordijk PL, Sixt M(2010). Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. Nat Rev Mol Cell Biol vol. 11, (5) 366-378.
10.1038/nrm2889
Leoni G, Voisin M-B, Carlson K, Getting S, Nourshargh S, Perretti M(2010). The melanocortin MC(1) receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculature. Br J Pharmacol vol. 160, (1) 171-180.
10.1111/j.1476-5381.2010.00688.x
Woodfin A, Voisin M-B, Nourshargh S(2010). Recent developments and complexities in neutrophil transmigration. Curr Opin Hematol vol. 17, (1) 9-17.
10.1097/MOH.0b013e3283333930
Voisin M-B, Pröbstl D, Nourshargh S(2010). Venular basement membranes ubiquitously express matrix protein low-expression regions: characterization in multiple tissues and remodeling during inflammation. Am J Pathol vol. 176, (1) 482-495.
10.2353/ajpath.2010.090510
Scheiermann C, Colom B, Meda P, Patel NSA, Voisin M-B, Marrelli A, Woodfin A, Pitzalis C et al.(2009). Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury. Arterioscler Thromb Vasc Biol vol. 29, (10) 1509-1515.
10.1161/ATVBAHA.109.187559
Voisin M-B, Woodfin A, Nourshargh S(2009). Monocytes and neutrophils exhibit both distinct and common mechanisms in penetrating the vascular basement membrane in vivo. Arterioscler Thromb Vasc Biol vol. 29, (8) 1193-1199.
10.1161/ATVBAHA.109.187450
Woodfin A, Voisin MB, Imhof BA, Dejana E, Engelhardt B, Nourshargh S(2009). Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. BLOOD vol. 113, (24) 6246-6257.
10.1182/blood-2008-11188375
Woodfin A, Voisin M-B, Imhof BA, Dejana E, Engelhardt B, Nourshargh S(2009). Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. Blood vol. 113, (24) 6246-6257.
10.1182/blood-2008-11-188375
Little MA, Smyth L, Salama AD, Mukherjee S, Smith J, Haskard D, Nourshargh S, Cook HT et al.(2009). Experimental autoimmune vasculitis: an animal model of anti-neutrophil cytoplasmic autoantibody-associated systemic vasculitis. Am J Pathol vol. 174, (4) 1212-1220.
10.2353/ajpath.2009.080458
Woodfin A, Voisin M-B, Nourshargh S(2007). PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler Thromb Vasc Biol vol. 27, (12) 2514-2523.
10.1161/ATVBAHA.107.151456
Scheiermann C, Meda P, Aurrand-Lions M, Madani R, Yiangou Y, Coffey P, Salt TE, Ducrest-Gay D et al.(2007). Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves. Science vol. 318, (5855) 1472-1475.
10.1126/science.1149276
Bradfield PF, Nourshargh S, Aurrand-Lions M, Imhof BA(2007). JAM family and related proteins in leukocyte migration (Vestweber series). Arterioscler Thromb Vasc Biol vol. 27, (10) 2104-2112.
10.1161/ATVBAHA.107.147694
Bradfield PF, Scheiermann C, Nourshargh S, Ody C, Luscinskas FW, Rainger GE, Nash GB, Miljkovic-Licina M et al.(2007). JAM-C regulates unidirectional monocyte transendothelial migration in inflammation. Blood vol. 110, (7) 2545-2555.
10.1182/blood-2007-03-078733
Woodfin A, Reichel CA, Khandoga A, Corada M, Voisin M-B, Scheiermann C, Haskard DO, Dejana E et al.(2007). JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration. Blood vol. 110, (6) 1848-1856.
10.1182/blood-2006-09-047431
Ley K, Laudanna C, Cybulsky MI, Nourshargh S(2007). Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol vol. 7, (9) 678-689.
10.1038/nri2156
NOURSHARGH S, Krombach F, Dejana E, Khandoga A, Woodfin A, Reichal AC, Haskard DO, Scheiermann C et al.(2007). JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: Evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration. Blood vol. 110, (6) 1848-1856.
10.1182/blood-2006-09-047431
Young RE, Voisin M-B, Wang S, Dangerfield J, Nourshargh S(2007). Role of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient mice. Br J Pharmacol vol. 151, (5) 628-637.
10.1038/sj.bjp.0707267
Voisin MB, Woodfin A, Nourshargh S (2007). Neutrophil and monocyte transmigration elicited by ischemia/reperfusion (I/R) injury and CCL2 is associated with remodelling of the venular basement membrane (BM) in vivo. FASEB JOURNAL. vol. 21, A127-A127.
Woodfin A, Larbi K, Krombach F, Dejana E, Nourshargh S (2007). PECAM-1 & JAM-A mediate leukocyte transmigration in a stimulus-specific manner: Is this phenomenon governed by the strain of mice investigated?. FASEB JOURNAL. vol. 21, A127-A127.
Potter PK, Larbi KY, Nourshargh S, Botto M(2007). Efficient clearance of opsonised apoptotic cells in the absence of PECAM-1. Mol Immunol vol. 44, (6) 1135-1140.
10.1016/j.molimm.2006.07.002
Nourshargh S, Krombach F, Dejana E(2006). The role of JAM-A and PECAM-1 in modulating leukocyte infiltration in inflamed and ischemic tissues. J Leukoc Biol vol. 80, (4) 714-718.
10.1189/jlb.1105645
Huang M-T, Larbi KY, Scheiermann C, Woodfin A, Gerwin N, Haskard DO, Nourshargh S(2006). ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1-independent transmigration. Blood vol. 107, (12) 4721-4727.
10.1182/blood-2005-11-4683
Wang S, Voisin M-B, Larbi KY, Dangerfield J, Scheiermann C, Tran M, Maxwell PH, Sorokin L et al.(2006). Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils. J Exp Med vol. 203, (6) 1519-1532.
10.1084/jem.20051210
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18599
Woodfin A, Reichel C, Khandoga A, Corada M, Haskard D, Dejana E, Krombach F, Nourshargh S (2006). JAM-A mediates leukocyte transmigration in a stimulus-specific manner. FASEB JOURNAL. vol. 20, A862-A862.
Voisin MB, Woodfin A, Dawes T, Nourshargh S (2006). Neutrophil elastase (NE) deficient mice exhibit reduced leukocyte transmigration in response to ischaemia/reperfusion (I/R) injury. FASEB JOURNAL. vol. 20, A1083-A1083.
Voisin MB, Wang SJ, Larbi K, Scheiermann C, Sorokin L, Nourshargh S (2006). Neutrophils play a direct role in enhancing the size of venular basement membrane (BM) matrix protein low expression regions. FASEB JOURNAL. vol. 20, A1322-A1322.
Tharp WG, Yadav R, Irimia D, Upadhyaya A, Samadani A, Hurtado O, Liu S-Y, Munisamy S et al.(2006). Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo. J Leukoc Biol vol. 79, (3) 539-554.
10.1189/jlb.0905516
Reichel CA, Khandoga A, Woodfin A, Corada M, Dejana E, Nourshargh S, Krombach F (2006). JAM-A mediates leukocyte transmigration dynamically and in a stimulus-specific manner. JOURNAL OF VASCULAR RESEARCH. vol. 43, 576-576.
Little MA, Bhangal G, Smyth CL, Nakada MT, Cook HT, Nourshargh S, Pusey CD (2006). Therapeutic effect of anti-TNF-alpha antibodies in an experimental model of anti-neutrophil cytoplasm antibody-associated systemic vasculitis. J Am Soc Nephrol. vol. 17, 160-169.
10.1681/ASN.2005060616
Ambrose LR, Little MA, Nourshargh S, Pusey CD(2005). Anti-proteinase 3 antibody binding to neutrophils as demonstrated by confocal microscopy. Kidney Int vol. 68, (6) 2912-2913.
10.1111/j.1523-1755.2005.00583_10.x
Little MA, Pusey CD, Nourshargh S (2005). Intravital microscopy in the study of ANCA-associated systemic vasculitis. Clin Nephrol. vol. 64, 465-470.
10.5414/cnp64465
Little MA, Smyth CL, Yadav R, Ambrose L, Cook HT, Nourshargh S, Pusey CD(2005). Antineutrophil cytoplasm antibodies directed against myeloperoxidase augment leukocyte-microvascular interactions in vivo. Blood vol. 106, (6) 2050-2058.
10.1182/blood-2005-03-0921
Chatterjee BE, Yona S, Rosignoli G, Young RE, Nourshargh S, Flower RJ, Perretti M(2005). Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro. J Leukoc Biol vol. 78, (3) 639-646.
10.1189/jlb.0405206
Aurrand-Lions M, Lamagna C, Dangerfield JP, Wang S, Herrera P, Nourshargh S, Imhof BA(2005). Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation. J Immunol vol. 174, (10) 6406-6415.
10.4049/jimmunol.174.10.6406
Wang S, Dangerfield JP, Young RE, Nourshargh S(2005). PECAM-1, alpha6 integrins and neutrophil elastase cooperate in mediating neutrophil transmigration. J Cell Sci vol. 118, (Pt 9) 2067-2076.
10.1242/jcs.02340
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