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Publications:  Prof Richard Leslie

Leslie RD, Grant SFA(2018). The Dynamic Origins of Type 1 Diabetes. Diabetes Care vol. 41, (12) 2441-2443.
10.2337/dci18-0034
Xiang Y, Huang G, Zhu Y, Zuo X, Liu X, Feng Q, Li X, Yang T et al.(2018). Identification of autoimmune type 1 diabetes and multiple organ-specific autoantibodies in adult-onset non-insulin-requiring diabetes in China: A population-based multicentre nationwide survey. Diabetes Obes Metab
10.1111/dom.13595
Cousminer DL, Ahlqvist E, Mishra R, Andersen MK, Chesi A, Hawa MI, Davis A, Hodge KM et al. (2018). First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. Diabetes Care. vol. 41, 2396-2403.
10.2337/dc18-1032
Achenbach P, Hawa MI, Krause S, Lampasona V, Jerram ST, Williams AJK, Bonifacio E, Ziegler AG et al.(2018). Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12. Diabetologia vol. 61, (7) 1644-1649.
10.1007/s00125-018-4605-3
Leslie RD, Lernmark Å(2018). Genetic risk scores in adult-onset type 1 diabetes. Lancet Diabetes Endocrinol vol. 6, (3) 168-169.
10.1016/S2213-8587(18)30039-1
Leslie RD, Grant SFA(2018). Teasing Diabetes Apart, One Locus at a Time. Diabetes Care vol. 41, (2) 224-226.
10.2337/dci17-0046
Toniolo A, Leslie RD(2017). Diabetes, the TYK2 Gene and the Interferon Response: In Search for Environmental Causes. EBioMedicine vol. 24, 18-19.
10.1016/j.ebiom.2017.09.003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34316
Jerram ST, Leslie RD(2017). The Genetic Architecture of Type 1 Diabetes. Genes (Basel) vol. 8, (8)
10.3390/genes8080209
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34408
Jerram ST, Dang MN, Leslie RD(2017). The Role of Epigenetics in Type 1 Diabetes. Curr Diab Rep vol. 17, (10)
10.1007/s11892-017-0916-x
Mishra R, Chesi A, Cousminer DL, Hawa MI, Bradfield JP, Hodge KM, Guy VC, Hakonarson H et al.(2017). Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes. BMC Med vol. 15, (1) 88-88.
10.1186/s12916-017-0846-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33988
Leslie RD, Jerram ST(2017). Stratifying Diabetes: Desperately Seeking Specificity. Diabetes vol. 66, (4) 801-803.
10.2337/dbi16-0074
Paul DS, Teschendorff AE, Dang MAN, Lowe R, Hawa MI, Ecker S, Beyan H, Cunningham S et al.(2016). Increased DNA methylation variability in type 1 diabetes across three immune effector cell types. Nat Commun vol. 7, 13555-13555.
10.1038/ncomms13555
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22321
Schloot NC, Pham MN, Hawa MI, Pozzilli P, Scherbaum WA, Schott M, Kolb H, Hunter S et al.(2016). Inverse Relationship Between Organ-Specific Autoantibodies and Systemic Immune Mediators in Type 1 Diabetes and Type 2 Diabetes: Action LADA 11. Diabetes Care vol. 39, (11) 1932-1939.
10.2337/dc16-0293
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22373
Yang Z, Wong A, Kuh D, Paul DS, Rakyan VK, Leslie RD, Zheng SC, Widschwendter M et al.(2016). Correlation of an epigenetic mitotic clock with cancer risk. Genome Biol vol. 17, (1)
10.1186/s13059-016-1064-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22365
Leslie RD, Jerram S(2016). Variation and the spice of life. Am J Clin Nutr vol. 104, (4) 955-956.
10.3945/ajcn.116.143313
Østergaard JA, Laugesen E, Leslie RD(2016). Should There be Concern About Autoimmune Diabetes in Adults? Current Evidence and Controversies. Curr Diab Rep vol. 16, (9)
10.1007/s11892-016-0780-0
Leslie RD, Palmer J, Schloot NC, Lernmark A(2016). Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment. Diabetologia vol. 59, (1) 13-20.
10.1007/s00125-015-3789-z
Dang MN, Bradford CM, Pozzilli P, Leslie RD(2016). Methylation Analysis in Distinct Immune Cell Subsets in Type 1 Diabetes. Methods Mol Biol vol. 1433, 143-151.
10.1007/7651_2015_286
O'Hare JP, Hanif W, Millar-Jones D, Bain S, Hicks D, Leslie RD, Barnett AH(2015). NICE guidelines for Type 2 diabetes: revised but still not fit for purpose. Diabet Med vol. 32, (11) 1398-1403.
10.1111/dme.12952
Wang B, Hawa MI, Rijsdijk FV, Fain PR, Paschou SA, Boehm BO, Steck AK, Snieder H et al.(2015). Heritability of thyroid peroxidase autoantibody levels in type 1 diabetes: evidence from discordant twin pairs. Diabetologia vol. 58, (9) 2079-2086.
10.1007/s00125-015-3664-y
O'Hare JP, Millar-Jones D, Hanif W, Hicks D, Leslie RD, Bain SC, Barnett AH(2015). The revised NICE draft guideline for type 2 diabetes: still a long way to go. Lancet Diabetes Endocrinol vol. 3, (9) 679-680.
10.1016/S2213-8587(15)00288-0
Lauria A, Barker A, Schloot N, Hosszufalusi N, Ludvigsson J, Mathieu C, Mauricio D, Nordwall M et al.(2015). BMI is an important driver of β-cell loss in type 1 diabetes upon diagnosis in 10 to 18-year-old children. Eur J Endocrinol vol. 172, (2) 107-113.
10.1530/EJE-14-0522
Migdalis I, Leslie D, Mavrogiannaki A, Papanas N, Valensi P, Vlassara H(2015). Diabetes Mellitus 2014. Int J Endocrinol vol. 2015,
10.1155/2015/845759
Leslie RDG, Bradford C(2014). Autoimmune diabetes: caught in a NET. Diabetes vol. 63, (12) 4018-4020.
10.2337/db14-1382
Juhl CB, Bradley U, Holst JJ, Leslie RD, Yderstraede KB, Hunter S, Consortium ALADA(2014). Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes: Action LADA 8. DIABETIC MEDICINE vol. 31, (8) 941-945.
10.1111/dme.12434
Hawa MI, Buchan AP, Ola T, Wun CC, DeMicco DA, Bao W, Betteridge DJ, Durrington PN et al.(2014). LADA and CARDS: a prospective study of clinical outcome in established adult-onset autoimmune diabetes. Diabetes Care vol. 37, (6) 1643-1649.
10.2337/dc13-2383
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7009
Zhao Y, Yang L, Xiang Y, Liu L, Huang G, Long Z, Li X, Leslie RD et al.(2014). Dipeptidyl peptidase 4 inhibitor sitagliptin maintains β-cell function in patients with recent-onset latent autoimmune diabetes in adults: one year prospective study. J Clin Endocrinol Metab vol. 99, (5) E876-E880.
10.1210/jc.2013-3633
Barker A, Lauria A, Schloot N, Hosszufalusi N, Ludvigsson J, Mathieu C, Mauricio D, Nordwall M et al.(2014). Age-dependent decline of β-cell function in type 1 diabetes after diagnosis: a multi-centre longitudinal study. Diabetes Obes Metab vol. 16, (3) 262-267.
10.1111/dom.12216
Hayes DF, Markus HS, Leslie RD, Topol EJ(2014). Personalized medicine: risk prediction, targeted therapies and mobile health technology. BMC MEDICINE vol. 12, Article ARTN 37,
10.1186/1741-7015-12-37
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22441
Migdalis I, Leslie D, Papanas N, Valensi P, Vlassara H(2014). Diabetes mellitus. Int J Endocrinol vol. 2014,
10.1155/2014/108419
Bradford CM, Hawa M, Sumaria N, Dang MN, Beyan H, Davies G, Jensen H, Tsang V et al. (2013). Understanding auto-antigen expression and regulation in human medullary thymic epithelial cells (mTECs). IMMUNOLOGY. vol. 140, 187-187.
Paschou SA, Leslie RD(2013). Personalizing guidelines for diabetes management: twilight or dawn of the expert?. BMC Med vol. 11,
10.1186/1741-7015-11-161
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23121
Gemma C, Ramagopalan SV, Down TA, Beyan H, Hawa MI, Holland ML, Hurd PJ, Giovannoni G et al.(2013). Inactive or moderately active human promoters are enriched for inter-individual epialleles. Genome Biol vol. 14, (5)
10.1186/gb-2013-14-5-r43
https://qmro.qmul.ac.uk/xmlui/handle/123456789/4899
Lowe R, Gemma C, Beyan H, Hawa MI, Bazeos A, Leslie RD, Montpetit A, Rakyan VK et al.(2013). Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies. Epigenetics vol. 8, (4) 445-454.
10.4161/epi.24362
Zhou Z, Xiang Y, Ji L, Jia W, Ning G, Huang G, Yang L, Lin J et al.(2013). Frequency, Immunogenetics, and Clinical Characteristics of Latent Autoimmune Diabetes in China (LADA China Study): A Nationwide, Multicenter, Clinic-Based Cross-Sectional Study. Diabetes vol. 62, (2) 543-550.
10.2337/db12-0207
Beyan H, Down TA, Ramagopalan SV, Uvebrant K, Nilsson A, Holland ML, Gemma C, Giovannoni G et al.(2012). Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans. Genome Res vol. 22, (11) 2138-2145.
10.1101/gr.134304.111
Beyan H, Wen L, Leslie RD(2012). Guts, germs, and meals: the origin of type 1 diabetes. Curr Diab Rep vol. 12, (5) 456-462.
10.1007/s11892-012-0298-z
Rajendram R, Fraser-Bell S, Kaines A, Michaelides M, Hamilton RD, Esposti SD, Peto T, Egan C et al.(2012). A 2-year prospective randomized controlled trial of intravitreal bevacizumab or laser therapy (BOLT) in the management of diabetic macular edema: 24-month data: report 3. Arch Ophthalmol vol. 130, (8) 972-979.
10.1001/archophthalmol.2012.393
Strom A, Menart B, Simon M-C, Pham MN, Kolb H, Roden M, Pozzilli P, Leslie RDG et al.(2012). Cellular interferon-γ and interleukin-13 immune reactivity in type 1, type 2 and latent autoimmune diabetes: action LADA 6. Cytokine vol. 58, (2) 148-151.
10.1016/j.cyto.2012.01.002
Beyan H, Riese H, Hawa MI, Beretta G, Davidson HW, Hutton JC, Burger H, Schlosser M et al.(2012). Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study. Diabetes vol. 61, (5) 1192-1198.
10.2337/db11-0971
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19765
Pham MN, Hawa MI, Roden M, Schernthaner G, Pozzilli P, Buzzetti R, Scherbaum WA, Seissler J et al.(2012). Increased serum concentrations of adhesion molecules but not of chemokines in patients with Type 2 diabetes compared with patients with Type 1 diabetes and latent autoimmune diabetes in adult age: action LADA 5. Diabet Med vol. 29, (4) 470-478.
10.1111/j.1464-5491.2011.03546.x
Adams D, Altucci L, Antonarakis SE, Ballesteros J, Beck S, Bird A, Bock C, Boehm B et al.(2012). BLUEPRINT to decode the epigenetic signature written in blood. NATURE BIOTECHNOLOGY vol. 30, (3) 224-226.
10.1038/nbt.2153
Bizzarri C, Pinto RM, Pitocco D, Astorri E, Cappa M, Hawa M, Giannone G, Palermo A et al.(2012). Diabetes-related autoantibodies in children with acute lymphoblastic leukemia. Diabetes Care vol. 35, (3)
10.2337/dc11-1946
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19616
Ludvigsson J, Krisky D, Casas R, Battelino T, Castaño L, Greening J, Kordonouri O, Otonkoski T et al.(2012). GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus. N Engl J Med vol. 366, (5) 433-442.
10.1056/NEJMoa1107096
Pham MN, Hawa MI, Pfleger C, Roden M, Schernthaner G, Pozzilli P, Buzzetti R, Scherbaum WA et al.(2012). Erratum to: Pro- and anti-inflammatory cytokines in latent autoimmune diabetes in adults, type 1 and type 2 diabetes patients: Action LADA 4. Diabetologia vol. 55, (2)
10.1007/s00125-011-2375-2
Hawa MI, Kolb H, Schloot N, Beyan H, Paschou SA, Buzzetti R, Mauricio D, De Leiva A et al.(2012). Adult-onset autoimmune diabetes in Europe is prevalent with a broad clinical phenotype: Action LADA 7. Diabetes Care
10.2337/dc12-0931
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18410
Leslie RD, Beyan H(2011). Metabolomics makes a mark: early changes associated with autoimmune diabetes. Diabetes vol. 60, (11) 2688-2690.
10.2337/db11-1177
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22550
Hadavi S, Noyce AJ, Leslie RD, Giovannoni G(2011). Stiff person syndrome. Pract Neurol vol. 11, (5) 272-282.
10.1136/practneurol-2011-000071
Leslie RD(2011). Towards secondary prevention of Type 1 diabetes. DIABETIC MED vol. 28, (10) 1140-1140.
10.1111/j.1464-5491.2011.03418.x
Rakyan VK, Beyan H, Down TA, Hawa MI, Maslau S, Aden D, Daunay A, Busato F et al.(2011). Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis. PLoS Genet vol. 7, (9)
10.1371/journal.pgen.1002300
https://qmro.qmul.ac.uk/xmlui/handle/123456789/5415
Leslie D (2011). Type 1 Diabetes-Not All in the Genes. JOURNAL OF MEDICAL VIROLOGY. vol. 83, 1670-1670.
10.1002/jmv.22065
Beyan H, Rakyan VK, Down TA, Hawa MI, Maslau S, Wallace C, Aden D, Mein CA et al. (2010). Identification of type 1 diabetes-associated methylation variable positions that precede disease diagnosis. DIABETOLOGIA. vol. 53, S145-S146.
10.1371/journal.pgen.1002300
Beyan H, Drexhage RC, van der Heul Nieuwenhuijsen L, de Wit H, Padmos RC, Schloot NC, Drexhage HA, Leslie RD(2010). Monocyte gene-expression profiles associated with childhood-onset type 1 diabetes and disease risk: a study of identical twins. Diabetes vol. 59, (7) 1751-1755.
10.2337/db09-1433
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23125
Michaelides M, Kaines A, Hamilton RD, Fraser-Bell S, Rajendram R, Quhill F, Boos CJ, Xing W et al.(2010). A Prospective Randomized Trial of Intravitreal Bevacizumab or Laser Therapy in the Management of Diabetic Macular Edema (BOLT Study) 12-Month Data: Report 2. OPHTHALMOLOGY vol. 117, (6) 1078-U76.
10.1016/j.ophtha.2010.03.045
Beyan H, Rakyan VK, Down TA, Maslau S, Hawa MI, Boehm BO, Beck S, Leslie RD (2010). Whole-Genome Identification and Functional Analysis of Type 1 Diabetes-Associated Epigenetic Variation. DIABETES. vol. 59, A56-A56.
Pozzilli P, Leslie RD, Chan J, De Fronzo R, Monnier L, Raz I, Del Prato S(2010). The A1C and ABCD of glycaemia management in type 2 diabetes: a physician's personalized approach. Diabetes Metab Res Rev vol. 26, (4) 239-244.
10.1002/dmrr.1092
Rakyan VK, Down TA, Maslau S, Andrew T, Yang T-P, Beyan H, Whittaker P, McCann OT et al.(2010). Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains. Genome Res vol. 20, (4) 434-439.
10.1101/gr.103101.109
Leslie RD(2010). Predicting adult-onset autoimmune diabetes: clarity from complexity. Diabetes vol. 59, (2) 330-331.
10.2337/db09-1620
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25551
Cernea S, Raz I, Herold KC, Hirshberg B, Roep BO, Schatz DA, Fleming GA, Pozzilli P et al.(2009). Challenges in developing endpoints for type 1 diabetes intervention studies. Diabetes Metab Res Rev vol. 25, (8) 694-704.
10.1002/dmrr.1002
Beyan H, Riese H, Hawa MI, Beretta G, Davidson HW, Hutton JC, Snieder H, Boehm BO et al. (2009). Common and unique environmental events associated with innate and adaptive immunity in type 1 diabetes. DIABETOLOGIA. vol. 52, S197-S198.
Leslie RDG, Cohen RM(2009). Biologic variability in plasma glucose, hemoglobin A1c, and advanced glycation end products associated with diabetes complications. J Diabetes Sci Technol vol. 3, (4) 635-643.
10.1177/193229680900300403
Leslie RD, Hawa MI, Schloot N, Sarti C, Williams R, Buzzetti R, Alemanno I, Kolb H et al. (2009). Frequency and Phenotypic Characteristics of Autoimmune Diabetes in Adult European Patients with Diabetes. DIABETES. vol. 58, A258-A258.
Pozzilli P, Leslie RD(2009). New prospects for immunotherapy at diagnosis of type 1 diabetes. DIABETES-METAB RES vol. 25, (4) 299-301.
10.1002/dmrr.970
Beyan H, Buckley LR, Bustin SA, Yousaf N, Pozzilli P, Leslie RD(2009). Altered monocyte cyclo-oxygenase response in non-obese diabetic mice. Clin Exp Immunol vol. 155, (2) 304-310.
10.1111/j.1365-2249.2008.03825.x
Padmos RC, Schloot NC, Beyan H, Ruwhof C, Staal FJT, de Ridder D, Aanstoot HJ, Lam-Tse WK et al.(2009). LADA Consortium: Distinct monocyte gene-expression profiles in autoimmune diabetes. (vol 57, pg 2768, 2008). DIABETES vol. 58, (1) 296-296.
Hawa MI, Thivolet C, Mauricio D, Alemanno I, Cipponeri E, Collier D, Hunter S, Buzzetti R et al.(2009). Metabolic Syndrome and Autoimmune Diabetes: Action LADA 3. DIABETES CARE vol. 32, (1) 160-164.
10.2337/dc08-1419
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19764
Allen JS, Pang K, Skowera A, Ellis R, Rackham C, Lozanoska-Ochser B, Tree T, Leslie RDG et al.(2009). Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture. DIABETES vol. 58, (1) 138-145.
10.2337/db08-0964
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28787
Leslie RDG, Kilpatrick ES(2009). Translating the A1C assay into estimated average glucose values: response to Nathan et al. Diabetes Care vol. 32, (1)
10.2337/dc08-1524
Lawson JM, Tremble J, Dayan C, Beyan H, Leslie RDG, Peakman M, Tree TIM(2008). Increased resistance to CD4(+)CD25(hi) regulatory T cell-mediated suppression in patients with type 1 diabetes. CLIN EXP IMMUNOL vol. 154, (3) 353-359.
10.1111/j.1365-2249.2008.03810.x
Leslie RDG, Kolb H, Schloot NC, Buzzetti R, Mauricio D, De Leiva A, Yderstraede K, Sarti C et al.(2008). Diabetes classification: grey zones, sound and smoke: Action LADA 1. DIABETES-METAB RES vol. 24, (7) 511-519.
10.1002/dmrr.877
Padmos RC, Schloot NC, Beyan H, Ruwhof C, Staal FJT, de Ridder D, Aanstoot H-J, Lam-Tse WK et al.(2008). Distinct monocyte gene-expression profiles in autoimmune diabetes. Diabetes vol. 57, (10) 2768-2773.
10.2337/db08-0496
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39567
Brophy S, Yderstraede K, Mauricio D, Hunter S, Hawa M, Pozzilli P, Schernthaner G, Schloot N et al.(2008). on behalf of the Action LADA Group: Time to insulin initiation cannot be used in defining latent autoimmune diabetes in adults. (vol 31, pg 439, 2008). DIABETES CARE vol. 31, (10) 2077-2077.
Leslie RDG, Beyan H, Drexhage HA, De Witt HJ(2008). Abnormal monocyte-related signatures in type 1 diabetes; a study of identical twins. DIABETOLOGIA vol. 51, S119-S119.
Schloot NC, Hawa MI, Scherbaum WA, Pozzilli P, Leslie R, Seissler J, Action LADA Consortium(2008). Organ specific autoantibodies in patients with type 1 diabetes, LADA and type 2 diabetes. DIABETOLOGIA vol. 51, S235-S235.
Beyan H, Von Hofe E, Leslie RD(2008). Study of T cell response to li-key/MHC class II epitope hybrides in human type 1 diabetes. DIABETOLOGIA vol. 51, S232-S232.
Hitman GA, Hawa MI, Leslie RDG, Ola T, Wun CC, DeMicco D, Betteridge DJ, Durrington PN et al.(2008). The clinical implications of GAD antibody positivity in older patients with established non-insulin requiring diabetes. DIABETOLOGIA vol. 51, S230-S231.
Hawa MI, Cipponeri E, Collier D, Loh Y, Pozzilli P, Brophy S, Hunter S, Thivolet C et al.(2008). The prevalence of metabolic syndrome is much less in LADA and type 1 diabetes than type 2 diabetes: ACTION LADA 3. DIABETOLOGIA vol. 51, S155-S155.
Beyan H, De Witt HJ, Drexhage HA, Leslie RD (2008). Abnormal monocyte-related signatures in type 1 diabetes: A study of identical twins. DIABETES. vol. 57, A89-A90.
Beyan H, Von Hofe E, Leslie RD (2008). Study of T cell response to Ii-Key/MHC class II epitope hybrides in human type 1 diabetes. DIABETES. vol. 57, A18-A18.
Brophy S, Yderstrede K, Mauricio D, Hunter S, Hawa M, Pozzilli P, Schernthaner G, Schoot N et al.(2008). Time to insulin initiation cannot be used in defining latent autoimmune diabetes in adults. DIABETES CARE vol. 31, (3) 439-441.
10.2337/dc07-1308
Mohsin F, Hitman G, Leslie R, Hawa M, Biswas K, Zabeen B, Nahar N, Azad K(2008). Clinical Profile and Autoantibody Status in Younger Onset Diabetes in Bangladesh. HORM RES vol. 70, 14-14.
Bevan H, De Witt HJ, Leslie RDG, Drexhage HA(2007). Abnormal monocyte-related signatures in type 1 diabetes; A study of identical twins. ACTA DIABETOL vol. 44, S4-S4.
Padmos RC, Schloot NC, Beyan H, Leslie RD, Drexhage HA, Act LADA Consortium(2007). Adult onset type 1 diabetes and LADA are discriminated from juvenile onset type 1 diabetes by a characteristic pro-inflammatory gene-expression signature in monocytes. ACTA DIABETOL vol. 44, S37-S38.
Beyan H, De Witt HJ, Leslie RDG, Dreyhage HA (2007). Abnormal monocyte-related biomarkers in type 1 diabetes; a study of identical twins. DIABETOLOGIA. vol. 50, S191-S191.
Zhou Z, Xiang Y, Yang L, Huang G, Yan X, Peng H, Liu Z, Hagopian W et al. (2007). LADA China Study 1: prevalence of latent autoimmune diabetes in adults among Chinese newly diagnosed type 2 diabetics. DIABETOLOGIA. vol. 50, S132-S132.
Xiang Y, Lin Y, Huang G, Yan X, Peng H, Liu Z, Hagopain W, Leslie RDG et al. (2007). Prevalence of metabolic syndrome in latent autoimmune diabetes in adults (LADA): data from a multicenter investigation (LADA China). DIABETOLOGIA. vol. 50, S131-S132.
Zhou ZG, Yang L, Xiang YF, Huang G, Yan X, Peng H, Liu ZQ, Hagopian W et al. (2007). LADA China study 1: Prevalence of latent autoimmune diabetes in adults (LADA) in China. DIABETES. vol. 56, A275-A275.
Beyan H, Humphreys RE, Von Hofe E, Leslie RD (2007). Study of T cell response to Ii-Key/MHC class Ii epitope hybrid peptides in human type 1 diabetes. DIABETES. vol. 56, A96-A96.
Beyan H, Goodier MR, Nawroly NS, Hawa MI, Bustin SA, Ogunkolade WB, Londei M, Yousaf N et al.(2007). Altered monocyte cyclooxygenase response to lipopolysaccharlde in type 1 diabetes.(vol 55, pg 3439, 2006). DIABETES vol. 56, (2) 549-549.
Beyan H, Goodier MR, Nawroly NS, Hawa MI, Bustin SA, Ogunkolade WB, Londei M, Yousaf N et al.(2006). Altered monocyte cyclooxygenase response to lipopolysaccharide in type 1 diabetes. Diabetes vol. 55, (12) 3439-3445.
10.2337/db06-0447
Teng J, Leslie RDG(2006). Type 1 diabetes and latent autoimmune diabetes in adults. Zhong Nan Da Xue Xue Bao Yi Xue Ban vol. 31, (6) 809-813.
Beyan H, Ola T, David R, Leslie G (2006). Progression of autoimmune diabetes: slowly progressive insulin-dependent diabetes mellitus or latent autoimmune diabetes of adult. Ann N Y Acad Sci. vol. 1079, 81-89.
10.1196/annals.1375.011
Hawa MI, Ola TO, Gigante A, Teng J, Leslie RDG, Action LADA consortium (2006). Action LADA, a multinational European project in latent autoimmune diabetes in adults (LADA). DIABETOLOGIA. vol. 49, 182-182.
Hassan Z, Hawa MI, Faruque MO, Biswas KB, Azad K, Khan AKA, Ali L, Leslie RDG et al. (2006). INSVNTR polymorphism in young onset diabetes subjects of Bangladesh. DIABETOLOGIA. vol. 49, 178-178.
Goodier MR, Nawroly N, Beyan H, Hawa M, Leslie RDG, Londei M(2006). Identical twins discordant for type 1 diabetes show a different pattern of in vitro CD56+ cell activation. Diabetes Metab Res Rev vol. 22, (5) 367-375.
10.1002/dmrr.627
Alper CA, Husain Z, Larsen CE, Dubey DP, Stein R, Day C, Baker A, Beyan H et al.(2006). Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes. J Autoimmun vol. 27, (2) 89-95.
10.1016/j.jaut.2006.07.007
Cohen RM, Snieder H, Lindsell CJ, Beyan H, Hawa MI, Blinko S, Edwards R, Spector TD et al. (2006). Evidence for independent heritability of the glycation gap, (glycosylation gap) fraction of HbA(1c) in nondiabetic twins. DIABETES CARE. vol. 29, 1739-1743.
10.2337/dc06-0286
Beyan H, Rakyana V, Hawa MI, Browne P, Beck S, Leslie DRD (2006). Epigenetic methylation of type 1 diabetes susceptibility genes. DIABETES. vol. 55, A545-A545.
Pozzilli P, Astorri E, Bizzari C, Cappa M, De Rossi G, Leslie RDG, Hawa M, Spoletini ML et al. (2006). GAD, IA2 and insulin autoantibodies in children diagnosed with acute lymphoblastic leukaemia: Relevance for type 1 diabetes. DIABETES. vol. 55, A412-A412.
Leslie RDG, Williams R, Pozzilli P(2006). Clinical review: Type 1 diabetes and latent autoimmune diabetes in adults: One end of the rainbow. J CLIN ENDOCR METAB vol. 91, (5) 1654-1659.
10.1210/jc.2005-1623
Ola TO, Gigante A, Leslie RDG(2006). Latent autoimmune diabetes of adults (LADA). NUTR METAB CARDIOVAS vol. 16, (3) 163-167.
10.1016/j.numecd.2005.08.003
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