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Publications:  Prof Hemant Kocher

Neuzillet C, Tijeras-Raballand A, Ragulan C, Cros J, Patil Y, Martinet M, Erkan M, Kleeff J et al.(2019). Inter- and intra-tumoural heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma. J Pathol vol. 248, (1) 51-65.
10.1002/path.5224
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56917
Roy M, Kyaw Tun J, Banerjee A, Mohandas S, Abraham AT, Hutchins RR, Bhattacharya S, Renfrew I et al.(2019). Factors affecting length of stay after percutaneous biliary interventions. Br J Radiol vol. 92, (1096)
10.1259/bjr.20180814
Coetzee A, Grose R, Kocher H(2019). Pancreatic Cancer Organotypic Models. Curr Top Microbiol Immunol
10.1007/82_2019_155
Spear S, Candido JB, McDermott JR, Ghirelli C, Maniati E, Beers SA, Balkwill FR, Kocher HM et al.(2019). Discrepancies in the Tumor Microenvironment of Spontaneous and Orthotopic Murine Models of Pancreatic Cancer Uncover a New Immunostimulatory Phenotype for B Cells. Front Immunol vol. 10,
10.3389/fimmu.2019.00542
Veenstra VL, Damhofer H, Waasdorp C, van Rijssen LB, van de Vijver MJ, Dijk F, Wilmink HW, Besselink MG et al.(2018). ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy. Oncogenesis vol. 7, (11)
10.1038/s41389-018-0096-9
McCluney SJ, Giakoustidis AA, Segler A, Bissel J, Miller RL, Valente R, Hutchins RR, Abraham A et al.(2018). Predicting complications in hepatic resection for colorectal liver metastasis: the lymphocyte-to-monocyte ratio. ANZ J Surg vol. 88, (11) E782-E786.
10.1111/ans.14725
Roy M, Ban EJ, Mohandas S, Mownah O, Banerjee A, Kocher H, Bhattacharya S, Hutchins R(2018). Re: Comparison of lipase and amylase for diagnosing post-operative pancreatic fistulae. ANZ J Surg vol. 88, (11) 1213-1214.
10.1111/ans.14890
McCluney S, Wijesuriya N, Sheshappanavar V, Chin-Aleong J, Feakins R, Hutchins R, Abraham A, Bhattacharya S et al.(2018). Solid pseudopapillary tumour of the pancreas: clinicopathological analysis. ANZ J Surg vol. 88, (9) 891-895.
10.1111/ans.14362
Raj D, Yang M-H, Rodgers D, Hampton EN, Begum J, Mustafa A, Lorizio D, Garces I et al.(2018). Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma. Gut
10.1136/gutjnl-2018-316595
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44123
McCluney SJ, Giakoustidis A, Segler A, Bissel J, Valente R, Hutchins RR, Abraham AT, Bhattacharya S et al.(2018). Neutrophil: Lymphocyte ratio as a method of predicting complications following hepatic resection for colorectal liver metastasis. J Surg Oncol vol. 117, (5) 1058-1065.
10.1002/jso.24996
Ghaneh P, Hanson R, Titman A, Lancaster G, Plumpton C, Lloyd-Williams H, Yeo ST, Edwards RT et al.(2018). PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer. Health Technol Assess vol. 22, (7) 1-114.
10.3310/hta22070
Neuzillet C, de Mestier L, Rousseau B, Mir O, Hebbar M, Kocher HM, Ruszniewski P, Tournigand C(2018). Unravelling the pharmacologic opportunities and future directions for targeted therapies in gastro-intestinal cancers part 2: Neuroendocrine tumours, hepatocellular carcinoma, and gastro-intestinal stromal tumours. Pharmacol Ther vol. 181, 49-75.
10.1016/j.pharmthera.2017.07.006
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25328
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D et al.(2017). Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov
10.1158/2159-8290.CD-17-0284
https://qmro.qmul.ac.uk/xmlui/handle/123456789/30984
CRNOGORAC-JURCEVIC T(2017). Non-invasive Diagnosis of Pancreatic Cancer Through Detection of Volatile Organic Compounds in Urine. Gastroenterology
10.1053/j.gastro.2017.09.054
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25665
Marzec J, Dayem Ullah AZ, Pirrò S, Gadaleta E, Crnogorac-Jurcevic T, Lemoine NR, Kocher HM, Chelala C(2017). The Pancreatic Expression Database: 2018 update. Nucleic Acids Res vol. 46, (D1) D1107-D1110.
10.1093/nar/gkx955
https://qmro.qmul.ac.uk/xmlui/handle/123456789/31471
Veenstra VL, Damhofer H, Waasdorp C, Steins A, Kocher HM, Medema JP, van Laarhoven HW, Bijlsma MF(2017). Stromal SPOCK1 supports invasive pancreatic cancer growth. Mol Oncol vol. 11, (8) 1050-1064.
10.1002/1878-0261.12073
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34314
Neuzillet C, Rousseau B, Kocher H, Bourget P, Tournigand C(2017). Unravelling the pharmacologic opportunities and future directions for targeted therapies in gastro-intestinal cancers Part 1: GI carcinomas. Pharmacol Ther vol. 174, 145-172.
10.1016/j.pharmthera.2017.02.028
McCluney SJ, Jamalfar A, Abraham AT, Kocher HM (2017). Surgical referrals at a major trauma centre: an unsustainable future?. BRITISH JOURNAL OF SURGERY. vol. 104, 41-41.
Kadaba RS, Bowers KA, Khorsandi S, Hutchins RR, Abraham AT, Sarker S-J, Bhattacharya S, Kocher HM(2017). Complications of biliary-enteric anastomoses. Ann R Coll Surg Engl vol. 99, (3) 210-215.
10.1308/rcsann.2016.0293
King H, Thillai K, Whale A, Arumugam P, Eldaly H, Kocher HM, Wells CM(2017). PAK4 interacts with p85 alpha: implications for pancreatic cancer cell migration. Sci Rep vol. 7, 42575-42575.
10.1038/srep42575
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34461
Arumugam P, Bhattacharya S, Chin-Aleong J, Capaso M, Kocher HM(2017). Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma. Pancreatology vol. 17, (2) 295-302.
10.1016/j.pan.2017.01.013
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25507
Solaini L, Atmaja BT, Arumugam P, Hutchins RR, Abraham AT, Bhattacharya S, Kocher HM(2016). The role of perioperative inflammatory-based prognostic systems in patients with colorectal liver metastases undergoing surgery. A cohort study. Int J Surg vol. 36, (Pt A) 8-12.
10.1016/j.ijsu.2016.10.010
Hariharan D, Junaid H, Bhattacharya S, Abraham A, Hutchins R, Preston S, Woodland P, Chin-Aleong J et al. (2016). Accuracy of EUS/FNAC in the management of solid, cystic and mixed lesions affecting the pancreas. BRITISH JOURNAL OF SURGERY. vol. 103, 8-8.
McCluney SJ, Balarajah V, Giakoustidis A, Chin-Aleong J, Lovett B, Kocher HM(2016). Intussuscepting Ampullary Adenoma: An Unusual Cause of Gastric Outlet Obstruction Leading to Cavitating Lung Lesions. Case Reports in Gastroenterology vol. 10, (3) 545-552.
10.1159/000450540
Balarajah V, Ambily A, Dayem Ullah AZ, Imrali A, Dowe T, Al-Sarireh B, Abu Hilal M, Davidson BR et al.(2016). Pancreatic cancer tissue banks: where are we heading?. Future Oncol vol. 12, (23) 2661-2663.
10.2217/fon-2016-0243
Carapuça EF, Gemenetzidis E, Feig C, Bapiro TE, Williams MD, Wilson AS, Delvecchio FR, Arumugam P et al.(2016). Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma. Journal of Pathology vol. 239, (3) 286-296.
10.1002/path.4727
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13271
GROSE RP, Dawkins JBN, Wang J, maniati, heward, koniali, kocher, martin et al.(2016). Reduced expression of histone methyltransferases KMT2C and KMT2D correlates with improved outcome in pancreatic ductal adenocarcinoma. Cancer Research
10.1158/0008-5472.CAN-16-0481
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12978
Di Maggio F, Arumugam P, Delvecchio FR, Batista S, Lechertier T, Hodivala-Dilke K, Kocher HM(2016). Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma. Pancreatology
10.1016/j.pan.2016.05.393
Ghaneh P, Wong WL, Titman A, Plumpton C, Vinjamuri S, Johnson C, Abu Hilal M, Higginson A et al. (2016). PET-PANC: Multi-centre prospective diagnostic accuracy and clinical value trial of FDG PET/CT in the diagnosis and management of suspected pancreatic cancer. JOURNAL OF CLINICAL ONCOLOGY. vol. 34,
10.1200/JCO.2016.34.15_suppl.4008
Arumugam P, Balarajah V, Watt J, Abraham AT, Bhattacharya S, Kocher HM(2016). Role of laparoscopy in hepatobiliary malignancies. Indian J Med Res vol. 143, (4) 414-419.
10.4103/0971-5916.184300
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34007
Coupland VH, Konfortion J, Jack RH, Allum W, Kocher HM, Riaz SP, Lüchtenborg M, Møller H(2016). Resection rate, hospital procedure volume and survival in pancreatic cancer patients in England: Population-based study, 2005-2009. Eur J Surg Oncol vol. 42, (2) 190-196.
10.1016/j.ejso.2015.11.003
Arumugam P, Fletcher N, Kyriakides C, Mears L, Kocher HM(2016). Lymphoepithelial Cyst of the Pancreas. Case Rep Gastroenterol vol. 10, (1) 181-192.
10.1159/000445373
Pantelidou C, Man YKS, Coughlan L, Marshall J, Kocher H, Hallden G(2016). Oncolytic adenoviral mutants deleted in the anti-apoptotic E1B19K gene sensitize pancreatic cancer cells to drug-induced DNA damage. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 38, S58-S58.
Balarajah V, Neuzillet C, Kocher HM(2016). Targeting pancreatic stellate cells to improve pancreatic cancer radiosensitivity. Translational Cancer Research vol. 5, S730-S737.
10.21037/tcr.2016.10.68
Alison M, Cereser B, Kocher H, McDonald SA (2015). Clonal analysis of the human liver reveals adaptable stem cell dynamics. HEPATOLOGY. vol. 62, 260A-260A.
Radon TP, Massat NJ, Jones R, Alrawashdeh W, Dumartin L, Ennis D, Duffy SW, Kocher HM et al.(2015). Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma. Clin Cancer Res vol. 21, (15) 3512-3521.
10.1158/1078-0432.CCR-14-2467
Reader CS, Vallath S, Morton J, Steele C, Kocher HM, Keyse SM, Sansom O, Marshall JF (2015). Cell lines generated from PDAC transgenic mice reveal integrin alpha v beta 6 modifies the invasive phenotype of pancreatic cancer. CANCER RESEARCH. vol. 75,
10.1158/1538-7445.PANCA2014-B87
Carapua EF, Gemenetzidis E, Feig C, Tuveson D, Kocher H (2015). Developing drug combinations to co-target pancreatic cancer and its supporting stroma. CANCER RESEARCH. vol. 75,
10.1158/1538-7445.PANCA2014-B72
Watt J, Siddique I, Dowe T, Crnogorac-Jurcevic T, Bhattacharya S, Allavena P, Kocher HM (2015). The role of Pentraxin 3 (PTX3) in pancreatic ductal adenocarcinoma. CANCER RESEARCH. vol. 75,
10.1158/1538-7445.PANCA2014-A56
Solaini L, Atmaja BT, Watt J, Arumugam P, Hutchins RR, Abraham AT, Bhattacharya S, Kocher HM(2015). Limited utility of inflammatory markers in the early detection of postoperative inflammatory complications after pancreatic resection: Cohort study and meta-analyses. Int J Surg vol. 17, 41-47.
10.1016/j.ijsu.2015.03.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12039
Solaini L, Jamieson NB, Metcalfe M, Abu Hilal M, Soonawalla Z, Davidson BR, McKay C, Kocher HM et al.(2015). Outcome after surgical resection for duodenal adenocarcinoma in the UK. Br J Surg vol. 102, (6) 676-681.
10.1002/bjs.9791
Viloria K, Ryall C, Dandagama A, Asher S, Lhaf F, King A, Jones P, Kocher H et al. (2015). Creating a 3D matricellular environment to promote islet expansion for diabetes therapy - the role of SPARC family proteins. FASEB JOURNAL. vol. 29,
Froeling FEM, Kocher HM(2015). Homeostatic restoration of desmoplastic stroma rather than its ablation slows pancreatic cancer progression. Gastroenterology vol. 148, (4) 849-850.
10.1053/j.gastro.2015.02.043
Wong P-P, Demircioglu F, Ghazaly E, Alrawashdeh W, Stratford MRL, Scudamore CL, Cereser B, Crnogorac-Jurcevic T et al.(2015). Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread. Cancer Cell vol. 27, (1) 123-137.
10.1016/j.ccell.2014.10.015
Wong P-P, Demircioglu F, Ghazaly E, Alrawashdeh W, Stratford M, Scudamore C, Cereser B, Crnogorac-Jurcevic T et al. (2015). NOVEL DUAL-ACTION COMBINATION THERAPY ENHANCES ANGIOGENESIS WHILST REDUCING TUMOR GROWTH AND SPREAD. JOURNAL OF VASCULAR RESEARCH. vol. 52, 6-6.
Debernardi S, Massat NJ, Radon TP, Sangaralingam A, Banissi A, Ennis DP, Dowe T, Chelala C et al.(2015). Noninvasive urinary miRNA biomarkers for early detection of pancreatic adenocarcinoma. Am J Cancer Res vol. 5, (11) 3455-3466.
Ryall CL, Viloria K, Lhaf F, Walker AJ, King A, Jones P, Mackintosh D, McNeice R et al.(2014). Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling. J Biol Chem vol. 289, (44) 30614-30624.
10.1074/jbc.M114.573980
Sunkel-Laing B, Kalam A, Renfrew I, Mears L, Kocher HM(2014). Repeated negative biopsies in isolated high-grade cystic duct dysplasia with progression to adenocarcinoma. Case Rep Gastroenterol vol. 8, (2) 304-309.
10.1159/000368114
Coleman SJ, Bruce C, Chioni A-M, Kocher HM, Grose RP(2014). The ins and outs of fibroblast growth factor receptor signalling. Clin Sci (Lond) vol. 127, (4) 217-231.
10.1042/CS20140100
Konfortion J, Coupland VH, Kocher HM, Allum W, Grocock MJ, Jack RH(2014). Time and deprivation trends in incidence of primary liver cancer subtypes in England. J Eval Clin Pract vol. 20, (4) 498-504.
10.1111/jep.12188
Coleman SJ, Watt J, Arumugam P, Solaini L, Carapuca E, Ghallab M, Grose RP, Kocher HM(2014). Pancreatic cancer organotypics: High throughput, preclinical models for pharmacological agent evaluation. World J Gastroenterol vol. 20, (26) 8471-8481.
10.3748/wjg.v20.i26.8471
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10915
Gill RMS, Michael A, Westley L, Kocher HM, Murphy JI, Dhoot GK(2014). SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression. Experimental Cell Research vol. 324, (2) 157-171.
10.1016/j.yexcr.2014.04.001
Gill RMS, Michael A, Westley L, Kocher HM, Murphy JI, Dhoot GK(2014). SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression. Exp Cell Res vol. 324, (2) 157-171.
10.1016/j.yexcr.2014.04.001
Solaini L, Sharma A, Watt J, Iosifidou S, Chin Aleong J-A, Kocher HM(2014). Predictive factors for incidental gallbladder dysplasia and carcinoma. J Surg Res vol. 189, (1) 17-21.
10.1016/j.jss.2014.01.064
Carapuca E, Gemenetzidis E, Feig C, Tuveson DA, Kocher H (2014). Developing Drug Combinations to Co-Target Pancreatic Cancer and Its Supporting Stroma. GASTROENTEROLOGY. vol. 146, S498-S498.
Watt J, Siddiqui I, Radon T, Dowe T, Crnogorac-Jurcevic T, Allavena P, Kocher H (2014). Pentraxin3 Is a Stromal Biomarker in Pancreatic Ductal Adenocarcinoma. GASTROENTEROLOGY. vol. 146, S276-S276.
Solaini L, Jamieson NB, Tamburrini R, Spoletini G, Abu Hilal M, Johnson CD, Soonawalla Z, Davidson B et al. (2014). UK Multicentre Surgical Experience With Primary Duodenal Adenocarcinoma. GASTROENTEROLOGY. vol. 146, S334-S334.
Coleman SJ, Chioni A-M, Ghallab M, Anderson RK, Lemoine NR, Kocher HM, Grose RP(2014). Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion. EMBO Mol Med vol. 6, (4) 467-481.
10.1002/emmm.201302698
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13773
Vyas S, Markar S, Partelli S, Fotheringham T, Low D, Imber C, Malago M, Kocher HM(2014). Portal vein embolization and ligation for extended hepatectomy. Indian J Surg Oncol vol. 5, (1) 30-42.
10.1007/s13193-013-0279-y
Watt J, Siddique I, Dowe T, Crnogorac-Jurcevic T, Allavena P, Kocher H(2014). Role of PTX3 in pancreatic cancer. LANCET vol. 383, 106-106.
Haider S, Wang J, Nagano A, Desai A, Arumugam P, Dumartin L, Fitzgibbon J, Hagemann T et al.(2014). A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma. Genome Med vol. 6, (12)
10.1186/s13073-014-0105-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6841
Coleman SJ, Grose RP, Kocher HM(2014). Fibroblast growth factor family as a potential target in the treatment of hepatocellular carcinoma. J Hepatocell Carcinoma vol. 1, 43-54.
10.2147/JHC.S48958
Arumugam P, Partelli S, Coleman SJ, Cataldo I, Beghelli S, Bassi C, Wijesuriya N, Aleong J-AC et al.(2013). Ezrin expression is an independent prognostic factor in gastro-intestinal cancers. J Gastrointest Surg vol. 17, (12) 2082-2091.
10.1007/s11605-013-2384-1
Gourgiotis S, Gemenetzis G, Kocher HM, Aloizos S, Salemis NS, Grammenos S(2013). Permissive hypotension in bleeding trauma patients: helpful or not and when?. Crit Care Nurse vol. 33, (6) 18-24.
10.4037/ccn2013395
Watt J, Kocher HM(2013). The desmoplastic stroma of pancreatic cancer is a barrier to immune cell infiltration. Oncoimmunology vol. 2, (12)
10.4161/onci.26788
Ene-Obong A, Clear AJ, Watt J, Wang J, Fatah R, Riches JC, Marshall JF, Chin-Aleong J et al.(2013). Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma. Gastroenterology vol. 145, (5) 1121-1132.
10.1053/j.gastro.2013.07.025
Sharma A, Iosifidou S, Qureishi A, Solaini L, Chin Aloeng JA, Kocher H(2013). Incidental gall bladder dysplasia and neoplasia in 21st century. Int J Surg vol. 11, (8)
10.1016/j.ijsu.2013.06.307
Gabriel J, Graham TA, Kocher H, Wright NA, Alison M, McDonald SAC (2013). Methylation Patterns of Clonally-Related Hepatocytes Provide Evidence of a Periportal Stem Cell Niche in the Normal Human Liver. JOURNAL OF PATHOLOGY. vol. 231, 15-15.
Kadaba R, Birke H, Wang J, Hooper S, Andl CD, Di Maggio F, Soylu E, Ghallab M et al.(2013). Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes. J Pathol vol. 230, (1) 107-117.
10.1002/path.4172
Coleman S, Chioni A-M, Ghallab M, Lemoine N, Grose RP, Kocher H (2013). Nuclear Translocation of FGFR1 and FGF2 in Pancreatic Stellate Cells Is Necessary for Pancreatic Cancer Cell Invasion. GASTROENTEROLOGY. vol. 144, S98-S98.
Ghallab MA, Rosignoli G, Escrig IS, Hurst HC, Hart IR, Bhattacharya S, Kocher HM (2013). Targeting pancreatic cancer stroma by HDAC inhibitors. BRITISH JOURNAL OF SURGERY. vol. 100, 4-4.
Jack RH, Konfortion J, Coupland VH, Kocher HM, Berry DP, Allum W, Linklater KM, Møller H(2013). Primary liver cancer incidence and survival in ethnic groups in England, 2001-2007. Cancer Epidemiol vol. 37, (1) 34-38.
10.1016/j.canep.2012.10.008
Milne R, La Vecchia C, Van Steen K, Hahn S, Buchholz M, Costello E, Esposito I, Hoheisel JD et al.(2013). EU Pancreas: an integrated European platform for pancreas cancer research--from basic science to clinical and public health interventions for a rare disease. Public Health Genomics vol. 16, (6) 305-312.
10.1159/000355937
Li NF, Gemenetzidis E, Marshall FJ, Davies D, Yu Y, Frese K, Froeling FEM, Woolf AK et al.(2013). RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells. PLoS One vol. 8, (12)
10.1371/journal.pone.0081575
Coward JIG, Ding N-L, Feakins R, Kocher H, Popat S, Szlosarek PW(2012). Chemotherapy-induced bowel obstruction in small cell lung cancer: a case report. Med Oncol vol. 29, (4) 2623-2625.
10.1007/s12032-011-0150-3
Vyas S, Bent C, Partelli S, Abraham AT, Hutchins RR, Bhattacharya S, Low D, Fotheringham T et al.(2012). Portal vein embolisation for extended hepatectomy: single-centre experience. J Gastrointest Cancer vol. 43, (3) 413-419.
10.1007/s12029-011-9321-x
Coupland VH, Kocher HM, Berry DP, Allum W, Linklater KM, Konfortion J, Møller H, Davies EA(2012). Incidence and survival for hepatic, pancreatic and biliary cancers in England between 1998 and 2007. Cancer Epidemiol vol. 36, (4) e207-e214.
10.1016/j.canep.2012.03.010
Guppy NJ, El-Bahrawy ME, Kocher HM, Fritsch K, Qureshi YA, Poulsom R, Jeffery RE, Wright NA et al.(2012). Trefoil factor family peptides in normal and diseased human pancreas. Pancreas vol. 41, (6) 888-896.
10.1097/MPA.0b013e31823c9ec5
Hariharan D, Constantinides V, Kocher HM, Tekkis PP(2012). The role of laparoscopy and laparoscopic ultrasound in the preoperative staging of patients with resectable colorectal liver metastases: a meta-analysis. Am J Surg vol. 204, (1) 84-92.
10.1016/j.amjsurg.2011.07.018
Naidoo K, Jones R, Dmitrovic B, Wijesuriya N, Kocher H, Hart IR, Crnogorac-Jurcevic T(2012). Proteome of formalin-fixed paraffin-embedded pancreatic ductal adenocarcinoma and lymph node metastases. J Pathol vol. 226, (5) 756-763.
10.1002/path.3959
Lines KE, Chelala C, Dmitrovic B, Wijesuriya N, Kocher HM, Marshall JF, Crnogorac-Jurcevic T(2012). S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells. Am J Pathol vol. 180, (4) 1485-1494.
10.1016/j.ajpath.2011.12.031
Kocher HM, Kadaba R(2011). Chronic pancreatitis. BMJ Clin Evid vol. 2011,
Gadaleta E, Cutts RJ, Kelly GP, Crnogorac-Jurcevic T, Kocher HM, Lemoine NR, Chelala C(2011). A global insight into a cancer transcriptional space using pancreatic data: importance, findings and flaws. Nucleic Acids Res vol. 39, (18) 7900-7907.
10.1093/nar/gkr533
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18659
Froeling FEM, Feig C, Chelala C, Dobson R, Mein CE, Tuveson DA, Clevers H, Hart IR et al.(2011). Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression. Gastroenterology vol. 141, (4) 1486-1497.14.
10.1053/j.gastro.2011.06.047
Coleman SJ, Myrto-Chioni A, Grose RP, Kocher H (2011). Investigating the Role of FGF Signaling in Pancreatic Cancer. GASTROENTEROLOGY. vol. 140, S714-S714.
Froeling F, Chelala C, Clevers H, Hart I, Kocher H (2011). Retinoic Acid-Induced Stellate Cell Quiescence Results in Sfrp4 Secretion Which Abrogates Wnt-beta-Catenin Signalling Pathway Modulating Human Pancreatic Tumour Cell Behaviour. GASTROENTEROLOGY. vol. 140, S156-S157.
Kadaba R, Froeling F, Soylu E, Bhattacharya S, Hart I, Kocher H (2011). The Ratio of Pancreatic Stellate Cells to Pancreatic Cancer Cells Plays a Critical Role in Modulating Carcinoma Cell Behaviour. GASTROENTEROLOGY. vol. 140, S713-S713.
Lines KE, Audi N, Chelala C, Wijesuriya N, Kocher H, Hurst H, Crnogorac-Jurcevic T(2011). Role of S100PBP in pancreatic adenocarcinoma. CANCER RESEARCH vol. 71,
10.1158/1538-7445.AM2011-1537
Kadaba R, Bowers KA, Wijesuriya N, Preston SL, Bray GB, Kocher HM(2011). An unusual cause of gastrointestinal bleeding: duodenal lipoma. Case Rep Gastroenterol vol. 5, (1) 183-188.
10.1159/000327219
Naidoo K, Al-Rawashdeh W, Hart IR, Crnogorac-Jurcevic T, Jones R, Wijesuriya N, Kocher HM(2011). The role of S100P expression in metastatic pancreatic ductal adenocarcinoma. CLIN EXP METASTAS vol. 28, (2) 165-165.
Soylu E, Junnarkar S, Kocher HM(2010). Recurrent indigestion in a young adult. Case Rep Gastroenterol vol. 4, (3) 518-523.
10.1159/000322871
Edling CE, Selvaggi F, Buus R, Maffucci T, Di Sebastiano P, Friess H, Innocenti P, Kocher HM et al.(2010). Key role of phosphoinositide 3-kinase class IB in pancreatic cancer. Clin Cancer Res vol. 16, (20) 4928-4937.
10.1158/1078-0432.CCR-10-1210
Hariharan D, Constantinides VA, Froeling FEM, Tekkis PP, Kocher HM(2010). The role of laparoscopy and laparoscopic ultrasound in the preoperative staging of pancreatico-biliary cancers--A meta-analysis. Eur J Surg Oncol vol. 36, (10) 941-948.
10.1016/j.ejso.2010.05.015
Froeling FEM, Marshall JF, Kocher HM(2010). Pancreatic cancer organotypic cultures. J Biotechnol vol. 148, (1) 16-23.
10.1016/j.jbiotec.2010.01.008
Kocher HM, Alrawashdeh W(2010). Pancreatic cancer. BMJ Clin Evid vol. 2010,
Ahmed I, Fotiadis NI, Dilks P, Kocher HM, Fotheringham T, Matson M(2010). Multiple intrahepatic artery aneurysms in a patient with Behçet's disease: use of transcatheter embolization for rupture. Cardiovasc Intervent Radiol vol. 33, (2) 398-401.
10.1007/s00270-009-9529-3
Lin W-R, Lim S-N, McDonald SAC, Graham T, Wright VL, Peplow CL, Humphries A, Kocher HM et al.(2010). The histogenesis of regenerative nodules in human liver cirrhosis. Hepatology vol. 51, (3) 1017-1026.
10.1002/hep.23483
Smith M, Kocher HM, Hunt BJ(2010). Aprotinin in severe acute pancreatitis. Int J Clin Pract vol. 64, (1) 84-92.
10.1111/j.1742-1241.2008.01899.x
Partelli S, Mukherjee S, Mawire K, Hutchins RR, Abraham AT, Bhattacharya S, Kocher HM(2010). Larger hepatic metastases are more frequent with N0 colorectal tumours and are associated with poor prognosis: implications for surveillance. Int J Surg vol. 8, (6) 453-457.
10.1016/j.ijsu.2010.05.013
Kocher HM, Dervenis C, Olah A, Murray WR, Clements B, Imrie CW (2010). Nutrition in Acute Pancreatitis. PANCREATIC DISEASE: PROTOCOLS AND CLINICAL RESEARCH. Editors: Johnson, CD, Imrie, CW, 31-40.
10.1007/978-1-84882-118-7_4
Jawad N, Woolf AK, Chin-Aleong J-A, Greaves R, Kocher HM(2009). Biliary Cystadenoma Causing Obstructive Jaundice: Case Report and Literature Review. Case Rep Gastroenterol vol. 3, (3) 269-274.
10.1159/000226254
Froeling FEM, Mirza TA, Feakins RM, Seedhar A, Elia G, Hart IR, Kocher HM(2009). Organotypic culture model of pancreatic cancer demonstrates that stromal cells modulate E-cadherin, beta-catenin, and Ezrin expression in tumor cells. Am J Pathol vol. 175, (2) 636-648.
10.2353/ajpath.2009.090131
Mukherjee S, Kocher HM, Hutchins RR, Bhattacharya S, Abraham AT(2009). Impact of hospital volume on outcomes for pancreaticoduodenectomy: a single UK HPB centre experience. Eur J Surg Oncol vol. 35, (7) 734-738.
10.1016/j.ejso.2008.04.006
Partelli S, Beg S, Brown J, Vyas S, Kocher HM(2009). Alteration in emergency theatre prioritisation does not alter outcome for acute appendicitis: comparative cohort study. World J Emerg Surg vol. 4,
10.1186/1749-7922-4-22
Fellous TG, McDonald SAC, Burkert J, Humphries A, Islam S, De-Alwis NMW, Gutierrez-Gonzalez L, Tadrous PJ et al.(2009). A methodological approach to tracing cell lineage in human epithelial tissues. Stem Cells vol. 27, (6) 1410-1420.
10.1002/stem.67
Fellous TG, Islam S, Tadrous PJ, Elia G, Kocher HM, Bhattacharya S, Mears L, Turnbull DM et al.(2009). Locating the stem cell niche and tracing hepatocyte lineages in human liver. Hepatology vol. 49, (5) 1655-1663.
10.1002/hep.22791
Iype S, Mirza TA, Propper DJ, Bhattacharya S, Feakins RM, Kocher HM(2009). Neuroendocrine tumours of the gallbladder: three cases and a review of the literature. Postgrad Med J vol. 85, (1002) 213-218.
10.1136/pgmj.2008.070649
Li NF, Kocher HM, Salako MA, Obermueller E, Sandle J, Balkwill F(2009). A novel function of colony-stimulating factor 1 receptor in hTERT immortalization of human epithelial cells. Oncogene vol. 28, (5) 773-780.
10.1038/onc.2008.412
Kocher HM, Sandle J, Mirza TA, Li NF, Hart IR(2009). Ezrin interacts with cortactin to form podosomal rosettes in pancreatic cancer cells. Gut vol. 58, (2) 271-284.
10.1136/gut.2008.159871
Iqbal N, Lovegrove RE, Tilney HS, Abraham AT, Bhattacharya S, Tekkis PP, Kocher HM(2009). A comparison of pancreaticoduodenectomy with extended pancreaticoduodenectomy: a meta-analysis of 1909 patients. Eur J Surg Oncol vol. 35, (1) 79-86.
10.1016/j.ejso.2008.01.002
Kocher HM, Froeling FE(2008). Chronic pancreatitis. BMJ Clin Evid vol. 2008,
10.1016/j.path.2016.05.008
Iqbal N, Lovegrove RE, Tilney HS, Abraham AT, Bhattacharya S, Tekkis PP, Kocher HM(2008). A comparison of pancreaticoduodenectomy with pylorus preserving pancreaticoduodenectomy: A meta-analysis of 2822 patients. EJSO-EUR J SURG ONC vol. 34, (11) 1237-1245.
10.1016/j.ejso.2007.12.004
Mohamedali A, Lea NC, Feakins RM, Raj K, Mufti GJ, Kocher HM(2008). AKT1 (E17K) mutation in pancreatic cancer. TECHNOL CANCER RES T vol. 7, (5) 407-408.
10.1177/153303460800700509
Gourgiotis S, Kocher HM, Solaini L, Yarollahi A, Tsiambas E, Salemis NS(2008). Gallbladder cancer. Am J Surg vol. 196, (2) 252-264.
10.1016/j.amjsurg.2007.11.011
Weeks ME, Hariharan D, Petronijevic L, Radon TR, Whiteman HJ, Kocher HM, Timms JF, Lemoine NR et al.(2008). Analysis of the urine proteome in patients with pancreatic ductal adenocarcinoma. PROTEOM CLIN APPL vol. 2, (7-8) 1047-1057.
10.1002/prca.200780164
Mai-Phan TA, Patel B, Walsh M, Abraham AT, Kocher HM(2008). Emergency room surgical workload in an inner city UK teaching hospital. World J Emerg Surg vol. 3,
10.1186/1749-7922-3-19
Kocher H, Sandle J, Mirza TA, Li NF, Hart IR(2008). A novel interaction of ezrin with cortactin in podosomal rosette assembly in pancreatic cancer cells. GASTROENTEROLOGY vol. 134, (4) A288-A288.
Froeling FE, Mirza TA, Li NF, Hart IR, Kocher H(2008). Organotypic culture modelling of pancreatic cancer. GASTROENTEROLOGY vol. 134, (4) A586-A586.
Li NF, Froeling FE, Hart IR, Kocher H(2008). RhoC enhances pancreatic carcinoma cell migration by mediating integrin signaling and podosome formation. GASTROENTEROLOGY vol. 134, (4) A288-A288.
Al-Ghnaniem R, Camprodon RAM, Kocher HM, Portmann B, Al-Nawab M, Shaikh H, Sohail M, Patel AG(2008). Strategy to reduce the risk of positive pancreatic resection margin at pancreatico-duodenectomy. ANZ J Surg vol. 78, (4) 237-239.
10.1111/j.1445-2197.2008.04427.x
Kocher HM(2008). Chronic pancreatitis. Am Fam Physician vol. 77, (5) 661-662.
Hariharan D, Saied A, Kocher HM(2008). Analysis of mortality rates for gallbladder cancer across the world. HPB (Oxford) vol. 10, (5) 327-331.
10.1080/13651820802007464
Hariharan D, Saied A, Kocher HM(2008). Analysis of mortality rates for pancreatic cancer across the world. HPB (Oxford) vol. 10, (1) 58-62.
10.1080/13651820701883148
O'Sullivan A, Kocher HM(2007). Pancreatic cancer. BMJ Clin Evid vol. 2007,
10.1017/CBO9780511575440
Kocher HM, Sohail M, Benjamin IS, Patel AG(2007). Technical limitations of lymph node mapping in pancreatic cancer. EJSO-EUR J SURG ONC vol. 33, (7) 887-891.
10.1016/j.ejso.2007.02.037
Kocher HM, Mears L, Lea NC, Raj K, Mufti GJ(2007). JAK V617F missense mutation is absent in pancreatic cancer. Gut vol. 56, (8) 1174-1175.
10.1136/gut.2006.117754
Germanos S, Gourgiotis S, Kocher HM(2007). Clinical update: early surgery for acute cholecystitis. Lancet vol. 369, (9575) 1774-1776.
10.1016/S0140-6736(07)60796-X
Fellous TG, Britian M, Kocher H, Bhattacharya S, Tadrous PJ, Taylor GA, Greaves LC, Mcdonald SA et al. (2007). Mitochondrial DNA mutations to investigate cell lineage relations in human liver. GASTROENTEROLOGY. vol. 132, A830-A830.
Baril P, Gangeswaran R, Mahon PC, Caulee K, Kocher HM, Harada T, Zhu M, Kalthoff H et al.(2007). Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway. Oncogene vol. 26, (14) 2082-2094.
10.1038/sj.onc.1210009
Mukherjee S, Kocher HM, Hutchins RR, Bhattacharya S, Abraham AT(2007). Palliative surgical bypass for pancreatic and peri-ampullary cancers. J Gastrointest Cancer vol. 38, (2-4) 102-107.
10.1007/s12029-008-9020-4
Kocher HM, Warwick J, Al-Ghnaniem R, Patel AG(2006). Surgical dexterity after a 'night out on the town'. ANZ J SURG vol. 76, (3) 110-112.
10.1111/j.1445-2197.2006.03664.x
Kocher HM, Senkus R, Al-Nawab M, Hendry BM(2005). Subcellular distribution of Ras GTPase isoforms in normal human kidney. NEPHROL DIAL TRANSPL vol. 20, (5) 886-891.
10.1093/ndt/gfh744
Kocher HM, Tekkis PP, Gopal P, Patel AG, Cottam S, Benjamin IS(2005). Risk-adjustment in hepatobiliary pancreatic surgery. World J Gastroenterol vol. 11, (16) 2450-2455.
10.3748/wjg.v11.i16.2450
Loong TPF, Kocher HM(2005). Clinical presentation and operative repair of hernia of Morgagni. POSTGRAD MED J vol. 81, (951) 41-44.
10.1136/pgmj.2004.022996
Kocher HM, Senkus R, Moorhead J, Al-Nawab M, Patel AG, Benjamin IS, Hendry BM(2005). Expression of Ras GTPase isoforms in normal and diseased pancreas. Pancreatology vol. 5, (2-3) 205-214.
10.1159/000085273
Tekkis PP, Prytherch DR, Kocher HM, Senapati A, Poloniecki JD, Stamatakis JD, Windsor ACJ(2004). Development of a dedicated risk-adjustment scoring system for colorectal surgery (colorectal POSSUM). Br J Surg vol. 91, (9) 1174-1182.
10.1002/bjs.4430
Kocher HM, Moorhead J, Sharpe CC, Dockrell MEC, Al-Nawab M, Hendry BM(2003). Expression of Ras GTPases in normal kidney and in glomerulonephritis. Nephrol Dial Transplant vol. 18, (11) 2284-2292.
10.1093/ndt/gfg375
Tekkis PP, Kessaris N, Kocher HM, Poloniecki JD, Lyttle J, Windsor ACJ(2003). Author's reply: Evaluation of POSSUM and P-POSSUM scoring systems in patients undergoing colorectal surgery (Br J Surg 2003; 90 : 340-345). BRIT J SURG vol. 90, (8) 1021-1021.
10.1002/bjs.4358
Kocher HM, Mohamed SA, Tekkis PP, Patel AG, Benjamin IS (2003). Prediction of mortality and morbidity in hepatopancreaticobiliary surgery. BRITISH JOURNAL OF SURGERY. vol. 90, 92-92.
Clarke HC, Kocher HM, Khwaja A, Kloog Y, Cook HT, Hendry BM(2003). Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis. J Am Soc Nephrol vol. 14, (4) 848-854.
10.1097/01.ASN.0000057543.55318.8B
Kocher HM, Tekkis PP(2003). Surgical treatment of esophageal cancer. N Engl J Med vol. 348, (12) 1177-1179.
10.1056/NEJM200303203481218
Tekkis PP, Kessaris N, Kocher HM, Poloniecki JD, Lyttle J, Windsor ACJ(2003). Evaluation of POSSUM and P-POSSUM scoring systems in patients undergoing colorectal surgery. Br J Surg vol. 90, (3) 340-345.
10.1002/bjs.4037
Kocher HM, Steward M, Leather AJM, Cullen PT(2002). Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure (Br J Surg 2002; 89: 413-17) - Reply. BRIT J SURG vol. 89, (9) 1193-1194.
10.1046/j.1365-2168.2002.02238_3.x
Kocher HM, Al-Ghnaniem R, Patel AG(2002). Surgical dexterity after a night out on the town. BRIT J SURG vol. 89, 17-17.
10.1046/j.1365-2168.89.s.1.9_1.x
Kocher HMK, Codd J, Al-Nawab M, Benjamin IS, Patel AG, Hendry BM(2002). Differential expression of RAS isoforms in normal and malignant human pancreas: An in vivo immunohistochemical analysis. GASTROENTEROLOGY vol. 122, (4) A495-A495.
Al-Ghnaniem R, Kocher HMK, Portmann B, Al-Nawab M, Sheik H, Sohail M, Patel AG(2002). Improving diagnostic accuracy of frozen section of the pancreatic resection margin at pancreatico-duodenectomy by concurrent examination of the suspected pancreatic lesion. GASTROENTEROLOGY vol. 122, (4) A566-A566.
Kocher HMK, Sohail M, Benjamin IS, Patel AG(2002). Lymph node mapping in pancreatic cancer: A feasibility study. GASTROENTEROLOGY vol. 122, (4) A495-A495.
Kocher HM, Steward M, Leather AJM, Cullen PT(2002). Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure. Br J Surg vol. 89, (4) 413-417.
10.1046/j.0007-1323.2001.02042.x
Kocher HMK, Patel AG, Benjamin IS(2002). World-wide trends in biliary tract cancer. GASTROENTEROLOGY vol. 122, (4) A569-A569.
Tekkis PP, Kocher HM, Kessaris N, Poloniecki J, Prytherch D, Somers SS, Mcculloch P, Ellut JPM et al.(2002). Risk adjustment in oesophagogastric surgery: a comparison of Bayesian analysis and logistic regression. BRIT J SURG vol. 89, (3) 381-381.
Al-Ghnaniem R, Kocher HM, Patel AG(2002). Prediction of inflammation of the appendix at open and laparoscopic appendicectomy: findings and consequences. Eur J Surg vol. 168, (1) 4-7.
10.1080/110241502317307490
Kua KB, Kocher HM, Kelkar A, Patel AG(2001). Effect of topical glyceryl trinitrate on anodermal blood flow in patients with chronic anal fissures. ANZ J Surg vol. 71, (9) 548-550.
10.1046/j.1440-1622.2001.02182.x
Kocher HM, Linklater Y, Patel S, Ellul JPM(2001). Epidemiological study of oesophageal and gastric cancer in south-east England. BRIT J SURG vol. 88, (9) 1249-1257.
10.1046/j.0007-1323.2001.01847.x
Kocher HM, Al-Ghnaniem R, Patel AG(2001). Major intra-abdominal pathology missed at laparoscopic cholecystectomy (Br J Surg 2000; 87: 1434-5). Br J Surg vol. 88, (6)
10.1046/j.1365-2168.2001.01814.x
Tekkis PP, Kocher HM, Kessaris N, Harrison TA, Slater N, Leather AJM, Windsor ACJ(2001). How accurate is POSSUM and p-POSSUM in predicting mortality in emergency surgery and in old age?. BRIT J SURG vol. 88, 42-43.
Kelkar AP, Kocher HM, Makar AA, Patel AG(2001). Extraction of retained gallstones from an abscess cavity: a percutaneous endoscopic technique. Surg Laparosc Endosc Percutan Tech vol. 11, (2) 129-130.
10.1097/00019509-200104000-00013
Kocher HM, Steward M, Leather AJ, Cullen PT(2001). Topical Glyceryl Tri-Nitrate [GTN] (0.2%) vs topical diltiazem (2%) in the treatment of chronic fissure-in-ano: A prospective double-blind randomised trial. GASTROENTEROLOGY vol. 120, (5) A130-A130.
Kocher HM, Codd J, Al-Nawab M, Benjamin IS, Patel AG, Hendry BM(2001). Differential expression of Ras isoforms in normal human pancreas: An in vivo immuno-histochemical analysis. GUT vol. 48, A70-A70.
Wong T, Kocher H, Kane P, Karani J, Patel A, Devlin J(2001). Evaluation of endoscopic ultrasound versus helical computed tomography in the assessment of pancreatic masses: Results from a UK centre. GUT vol. 48, A65-A65.
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