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Publications:  Prof Marta Korbonits

Marques P, Korbonits M (2017) . Genetic Aspects of Pituitary Adenomas.Endocrinology and Metabolism Clinics of North America vol. 46, (2) 335-374.
10.1016/j.ecl.2017.01.004
http://qmro.qmul.ac.uk/xmlui/handle/123456789/22763
Kiefer FW, Winhofer Y, Iacovazzo D et al. (2017) . PRKAR1A mutation causing pituitary-dependent Cushing disease in a patient with Carney complex.Eur J Endocrinol
10.1530/EJE-17-0227
Shaid M, Korbonits M (2017) . Genetics of pituitary adenomas.Neurology India vol. 65, (3) 577-587.
10.4103/neuroindia.NI_330_17
Bulwer C, Conn R, Shankar A et al. (2017) . Cabergoline-related impulse control disorder in an adolescent with a giant prolactinoma.Clinical Endocrinology
10.1111/cen.13339
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23084
Doleschall M, Luczay A, Koncz K et al. (2017) . A unique haplotype of RCCX copy number variation: from the clinics of congenital adrenal hyperplasia to evolutionary genetics.European Journal of Human Genetics
10.1038/ejhg.2017.38
http://qmro.qmul.ac.uk/xmlui/handle/123456789/24509
Asa SL, Casar-Borota O, Chanson P et al. (2017) . From pituitary adenoma to pituitary neuroendocrine tumor (pitnet): An international pituitary pathology club proposal.Endocrine-Related Cancer vol. 24, (4) C5-C8.
10.1530/ERC-17-0004
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23610
Tufton N, Roncaroli F, Hadjidemetriou I et al. (2017) . Pituitary Carcinoma in a Patient with an SDHB Mutation.Endocr Pathol
10.1007/s12022-017-9474-7
Iacovazzo D, Hernández-Ramírez LC, Korbonits M (2017) . Sporadic pituitary adenomas: the role of germline mutations and recommendations for genetic screening.Expert Review of Endocrinology and Metabolism vol. 12, (2) 143-153.
10.1080/17446651.2017.1306439
http://qmro.qmul.ac.uk/xmlui/handle/123456789/22683
Seelig E, Meyer S, Timper K et al. (2017) . Metformin prevents metabolic side effects during systemic glucocorticoid treatment.Eur J Endocrinol vol. 176, (3) 349-358.
10.1530/EJE-16-0653
http://qmro.qmul.ac.uk/xmlui/handle/123456789/21739
Thomas JDJ, Dattani A, Zemrak F et al. (2017) . Renin-Angiotensin System Blockade Improves Cardiac Indices in Acromegaly Patients.Experimental and Clinical Endocrinology and Diabetes
10.1055/s-0042-123710
http://qmro.qmul.ac.uk/xmlui/handle/123456789/21839
Roncaroli F, Iacovazzo D, Rodd C et al. (2017) . Distinct pathological features of pituitary adenomas in patients with X-linked acrogigantism (XLAG). NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. vol. 43, 20-20.
Tufton N, Shapiro L, Srirangalingam U et al. (2017) . Outcomes of annual surveillance imaging in an adult and paediatric cohort of succinate dehydrogenase B mutation carriers.Clin Endocrinol (Oxf) vol. 86, (2) 286-296.
10.1111/cen.13246
Roncaroli F, Tufton N, Hadjidemetriou I et al. (2017) . Pituitary carcinoma in a patient with germline Succinate Dehydrogenase B mutation. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. vol. 43, 46-46.
Srirangalingam U, Banerjee A, Patki P et al. (2017) . Succinate Dehydrogenase B (SDHB)-Associated Bladder Paragangliomas.Clin Genitourin Cancer vol. 15, (1) e131-e136.
10.1016/j.clgc.2016.06.006
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23044
Gadelha MR, Kasuki L, Korbonits M (2017) . The genetic background of acromegaly.Pituitary vol. 20, (1) 10-21.
10.1007/s11102-017-0789-7
http://qmro.qmul.ac.uk/xmlui/handle/123456789/21959
Radian S, Diekmann Y, Gabrovska P et al. (2017) . Increased Population Risk of AIP-Related Acromegaly and Gigantism in Ireland.Hum Mutat vol. 38, (1) 78-85.
10.1002/humu.23121
http://qmro.qmul.ac.uk/xmlui/handle/123456789/17888
Mitra MT, Jönsson P, Åkerblad AC et al. (2017) . Social, educational and vocational outcomes in patients with childhood-onset and young-adult-onset growth hormone deficiency.Clinical Endocrinology
10.1111/cen.13291
http://qmro.qmul.ac.uk/xmlui/handle/123456789/22060
Butz H, Németh K, Czenke D et al. (2016) . Systematic Investigation of Expression of G2/M Transition Genes Reveals CDC25 Alteration in Nonfunctioning Pituitary Adenomas.Pathology and Oncology Research1-9.
10.1007/s12253-016-0163-5
http://qmro.qmul.ac.uk/xmlui/handle/123456789/18822
Iacovazzo D, Caswell R, Bunce B et al. (2016) . Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study.Acta Neuropathologica Communications vol. 4, (1)
10.1186/s40478-016-0328-1
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23056
Caimari F, Korbonits M (2016) . Novel genetic causes of pituitary adenomas.Clinical Cancer Research vol. 22, (20) 5030-5042.
10.1158/1078-0432.CCR-16-0452
http://qmro.qmul.ac.uk/xmlui/handle/123456789/17893
Iacovazzo D, Korbonits M (2016) . Gigantism: X-linked acrogigantism and GPR101 mutations.Growth Horm IGF Res vol. 30-31, 64-69.
10.1016/j.ghir.2016.09.007
http://qmro.qmul.ac.uk/xmlui/handle/123456789/18720
Ramírez-Rentería C, Hernández-Ramírez LC, Portocarrero-Ortiz L et al. (2016) . AIP mutations in young patients with acromegaly and the Tampico Giant: the Mexican experience.Endocrine vol. 53, (2) 402-411.
10.1007/s12020-016-0930-9
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15024
Hernández-Ramírez LC, Martucci F, Morgan RML et al. (2016) . Rapid Proteasomal Degradation of Mutant Proteins Is the Primary Mechanism Leading to Tumorigenesis in Patients With Missense AIP Mutations.Journal of Clinical Endocrinology and Metabolism vol. 101, (8) 3144-3154.
10.1210/jc.2016-1307
http://qmro.qmul.ac.uk/xmlui/handle/123456789/17773
Ferreira VM, Marcelino M, Piechnik SK et al. (2016) . Pheochromocytoma Is Characterized by Catecholamine-Mediated Myocarditis, Focal and Diffuse Myocardial Fibrosis, and Myocardial Dysfunction.J Am Coll Cardiol vol. 67, (20) 2364-2374.
10.1016/j.jacc.2016.03.543
http://qmro.qmul.ac.uk/xmlui/handle/123456789/14450
Vujovic S, Vujosevic S, Kavaric S et al. (2016) . Cancerous leptomeningitis and familial congenital hypopituitarism.Endocrine vol. 52, (2) 231-235.
10.1007/s12020-016-0868-y
Rodd C, Millette M, Iacovazzo D et al. (2016) . Somatic GPR101 Duplication Causing X-Linked Acrogigantism (XLAG)—Diagnosis and Management.The Journal of Clinical Endocrinology & Metabolism vol. 101, (5) 1927-1930.
10.1210/jc.2015-4366
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13770
Bolger GB, Bizzi MF, Pinheiro SV et al. (2016) . cAMP-specific PDE4 phosphodiesterases and AIP in the pathogenesis of pituitary tumors.Endocrine-Related Cancer vol. 23, (5) 419-431.
10.1530/ERC-15-0205
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15022
Koehler VF, Jungheim K, Gross U et al. (2016) . Novel germline p.Gly42Val MEN1 mutation in a family with multiple endocrine neoplasia type 1.
Dutta P, Korbonits M, Sachdeva N et al. (2016) . Can immediate postoperative random growth hormone levels predict long-term cure in patients with acromegaly?.Neurology India vol. 64, (2) 252-258.
10.4103/0028-3886.177622
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15026
Syro LV, Rotondo F, Kovacs K et al. (2016) . Clinicopathologic features of familial pituitary adenomas.Diagnostic Histopathology vol. 22, (3) 85-91.
10.1016/j.mpdhp.2016.02.004
Strasburger CJ, Karavitaki N, Störmann S et al. (2016) . Patient-reported outcomes of parenteral somatostatin analogue injections in 195 patients with acromegaly.Eur J Endocrinol vol. 174, (3) 355-362.
10.1530/EJE-15-1042
http://qmro.qmul.ac.uk/xmlui/handle/123456789/12718
Iacovazzo D, Carlsen E, Lugli F et al. (2016) . Factors predicting pasireotide responsiveness in somatotroph pituitary adenomas resistant to first-generation somatostatin analogues: an immunohistochemical study.Eur J Endocrinol vol. 174, (2) 241-250.
10.1530/EJE-15-0832
Scagliotti V, Avagliano L, Gualtieri A et al. (2016) . Histopathology and molecular characterisation of intrauterine-diagnosed congenital craniopharyngioma.Pituitary vol. 19, (1) 50-56.
10.1007/s11102-015-0682-1
Scagliotti V, Avagliano L, Gualtieri A et al. (2016) . Histopathology and molecular characterisation of intrauterine-diagnosed congenital craniopharyngioma.Pituitary vol. 19, (1) 50-56.
10.1007/s11102-015-0682-1
Hernandez-Ramirez LC, Morgan RML, Chrisostomos Prodromou C et al. (2016) . A Proteomic Approach to Unveil the Pituitary-Specific Tumour Suppressor Mechanisms of AIP. Conference: Endocr. RevSUN-505.
Portocarrero-Ortiz L, Martinez-Gigena MP, Alcocer-Barradas V et al. (2016) . Clinical Case : Gigantism Due to AIP Mutation in a 9 Years-Old Identical Twin. Conference: Endocr. RevSUN-566.
Caimari F, Dang MN, Hernandez-Ramirez LC et al. (2016) . Clinical Characteristics Predicting AIP Mutation Status in Pituitary Adenoma Patients. Conference: Endocr. RevOR42-OR45.
Korbonits M, Dutta P, Reddy KS et al. (2016) . Exome Sequencing Reveals Double Hit By AIP Gene Mutation and Copy Loss of Chromosome 11 but Negative X-LAG in a Pituitary Adenoma of a 4 Yrs Child with Gigantism Treated with Multimodal Therapy. Conference: Endocr. RevLBSat-27.
Scudder CJ, Mirczuk SM, Richardson KM et al. (2016) . Feline Hypersomatotropism As a Spontaneous Animal Model of Acromegaly: Molecular Analyses of Somatostatin and Dopamine Receptor Expression in GH-Secreting Adenomas in the Cat (Felis catus). Conference: Endocr. RevLBSat-29.
Iacovazzo D, Kapur S, Bunce B et al. (2016) . GPR101 Variants in Acromegaly: Results from a Large Series of Patients. Conference: Endocr. RevSUN-534.
Dworakowska D, Paulina Szyszka P, Diaz-Cano SJ et al. (2016) . Metformin Alters an Anti-Proliferative Effect of Mitotane in a Human Adrenocortical Cancer (H295R) Cell Line: Preliminary Results. Conference: Endocr. RevSAT-411.
Korbonits M, Millette M, Iacovazzo D et al. (2016) . Somatic Xq26.3 Microduplication Causing X-Linked Acrogigantism (X-LAG). Conference: Endocr. RevLBSat-28.
Iacovazzo D, Jose S, Bunce B et al. (2016) . X-Linked Acrogigantism (X-LAG): Novel Histopathological and Clinical Characterisation. Conference: Endocr. RevOR42-OR44.
Renukanthan A, Quinton R, Turner B et al. (2015) . Kallmann syndrome patient with gender dysphoria, multiple sclerosis, and thrombophilia.Endocrine vol. 50, (2) 496-503.
10.1007/s12020-015-0562-5
Agustsson TT, Baldvinsdottir T, Jonasson JG et al. (2015) . The epidemiology of pituitary adenomas in Iceland, 1955-2012: a nationwide population-based study.Eur J Endocrinol vol. 173, (5) 655-664.
10.1530/EJE-15-0189
Ferraù F, Korbonits M (2015) . Metabolic comorbidities in Cushing's syndrome. Eur J Endocrinol. vol. 173, M133-M157.
10.1530/EJE-15-0354
Hernández-Ramírez LC, Gabrovska P, Dénes J et al. (2015) . Landscape of Familial Isolated and Young-Onset Pituitary Adenomas: Prospective Diagnosis in AIP Mutation Carriers.J Clin Endocrinol Metab vol. 100, (9) E1242-E1254.
10.1210/jc.2015-1869
Ribeiro-Oliveira A, Marques MB, Vilas-Boas WW et al. (2015) . The effects of chronic candesartan treatment on cardiac and hepatic adenosine monophosphate-activated protein kinase in rats submitted to surgical stress.J Renin Angiotensin Aldosterone Syst vol. 16, (3) 481-487.
10.1177/1470320313499199
O'Toole SM, Dénes J, Robledo M et al. (2015) . 15 YEARS OF PARAGANGLIOMA: The association of pituitary adenomas and phaeochromocytomas or paragangliomas.Endocr Relat Cancer vol. 22, (4) T105-T122.
10.1530/ERC-15-0241
http://qmro.qmul.ac.uk/xmlui/handle/123456789/8661
Kumar S, Yadav RN, Gupta P et al. (2015) . Prostatic hyperplasia in acromegaly, a myth or reality: a case-control study.Eur J Endocrinol vol. 173, (2)
10.1530/EJE-14-0698e
Perez-Rivas LG, Theodoropoulou M, Ferraù F et al. (2015) . The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease.J Clin Endocrinol Metab vol. 100, (7) E997-1004.
10.1210/jc.2015-1453
Müller TD, Nogueiras R, Andermann ML et al. (2015) . Ghrelin.Mol Metab vol. 4, (6) 437-460.
10.1016/j.molmet.2015.03.005
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13772
Lim SV, Marenzana M, Hopkinson M et al. (2015) . Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength.Endocrinology vol. 156, (4) 1362-1371.
10.1210/en.2014-1572
Gardner CJ, Mattsson AF, Daousi C et al. (2015) . GH deficiency after traumatic brain injury: improvement in quality of life with GH therapy: analysis of the KIMS database.Eur J Endocrinol vol. 172, (4) 371-381.
10.1530/EJE-14-0654
Melmed S, Popovic V, Bidlingmaier M et al. (2015) . Safety and efficacy of oral octreotide in acromegaly: results of a multicenter phase III trial.J Clin Endocrinol Metab vol. 100, (4) 1699-1708.
10.1210/jc.2014-4113
Dénes J, Swords F, Rattenberry E et al. (2015) . Heterogeneous genetic background of the association of pheochromocytoma/paraganglioma and pituitary adenoma: results from a large patient cohort.J Clin Endocrinol Metab vol. 100, (3) E531-E541.
10.1210/jc.2014-3399
Ferreira VM, Marcelino M, Piechnik SK et al. (2015) . Multi-parametric cardiovascular magnetic resonance imaging detects subclinical myocardial involvement in patients diagnosed with phaeochromocytoma.Journal of Cardiovascular Magnetic Resonance1-2.
10.1186/1532-429X-17-S1-P271
Diaz-Cano S, Szyszka P, Weitsman G et al. (2015) . Effect of Erlotinib on Proliferation and Steriodogenesis in Primary Cultures of Adrenocortical Carcinoma. MODERN PATHOLOGY. vol. 28, 133A-133A.
Soh LM, Druce M, Grossman AB et al. (2015) . Evaluation of genotype-phenotype relationships in patients referred for endocrine assessment in suspected Pendred syndrome.Eur J Endocrinol vol. 172, (2) 217-226.
10.1530/EJE-14-0679
Kumar S, Yadav RN, Gupta P et al. (2015) . Prostatic hyperplasia in acromegaly, a myth or reality: a case-control study.Eur J Endocrinol vol. 172, (2) 97-106.
10.1530/EJE-14-0698
Glynn NGL, Korbonits M (2015) . A 25-year-old woman with headache and joint pain.Endocrinology and Diabetes: Case Studies, Questions and Commentaries,
Iacovazzo D, Piacentini S, Lugli F et al. (2015) . A Novel MEN1 Gene Variant in a Sporadic Case of Multiple Endocrine Neoplasia Type 1. NEUROENDOCRINOLOGY. vol. 102, 150-150.
Nölting S, Maurer J, Spöttl G et al. (2015) . Additive Anti-Tumor Effects of Lovastatin and Everolimus In Vitro through Simultaneous Inhibition of Signaling Pathways.PLoS One vol. 10, (12)
10.1371/journal.pone.0143830
http://qmro.qmul.ac.uk/xmlui/handle/123456789/12719
Dutta P, Hajela A, Pathak A et al. (2015) . Clinical profile and outcome of patients with acromegaly according to the 2014 consensus guidelines: Impact of a multi-disciplinary team.Neurology India vol. 63, (3) 360-368.
10.4103/0028-3886.158210
Dénes J, Kasuki L, Trivellin G et al. (2015) . Regulation of aryl hydrocarbon receptor interacting protein (AIP) protein expression by MiR-34a in sporadic somatotropinomas.PLoS One vol. 10, (2)
10.1371/journal.pone.0117107
http://qmro.qmul.ac.uk/xmlui/handle/123456789/6951
Niessen SJM, Forcada Y, Mantis P et al. (2015) . Studying Cat (Felis catus) Diabetes: Beware of the Acromegalic Imposter.PLoS One vol. 10, (5)
10.1371/journal.pone.0127794
Larkin SJ, Ferraù F, Karavitaki N et al. (2014) . Sequence analysis of the catalytic subunit of PKA in somatotroph adenomas.Eur J Endocrinol vol. 171, (6) 705-710.
10.1530/EJE-14-0545
Preda V, Korbonits M, Cudlip S et al. (2014) . Low rate of germline AIP mutations in patients with apparently sporadic pituitary adenomas before the age of 40: a single-centre adult cohort.Eur J Endocrinol vol. 171, (5) 659-666.
10.1530/EJE-14-0426
Solomou S, Korbonits M (2014) . The role of ghrelin in weight-regulation disorders: implications in clinical practice.Hormones (Athens) vol. 13, (4) 458-475.
10.14310/horm.2002.1551
Iacovazzo D, Sampson JR, Morrison PJ et al. (2014) . Five families with RET-mutation negative familial medullary thyroid carcinoma: what lies beyond RET?.WIENER KLINISCHE WOCHENSCHRIFT vol. 126, S141-S142.
Nölting S, Giubellino A, Tayem Y et al. (2014) . Combination of 13-Cis retinoic acid and lovastatin: marked antitumor potential in vivo in a pheochromocytoma allograft model in female athymic nude mice.Endocrinology vol. 155, (7) 2377-2390.
10.1210/en.2014-1027
de Kock L, Sabbaghian N, Plourde F et al. (2014) . Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations.Acta Neuropathol vol. 128, (1) 111-122.
10.1007/s00401-014-1285-z
Tritos NA, Johannsson G, Korbonits M et al. (2014) . Effects of long-term growth hormone replacement in adults with growth hormone deficiency following cure of acromegaly: a KIMS analysis.J Clin Endocrinol Metab vol. 99, (6) 2018-2029.
10.1210/jc.2014-1013
Iacovazzo D, Morrison PJ, Foulkes W et al. (2014) . Four Families with RET-Mutation Negative Familial Medullary Thyroid Carcinoma: What Lies Beyond RET?.ENDOCRINE REVIEWS vol. 35, (3)
Butz H, Szabo PM, Igaz P et al. (2014) . Integrative Analysis of Chromosomal, Trancriptome, Proteomic and Mirnome Data Reveals Involvement of Impaired Developmental Processes in Clinically Non-Functional Pituitary Adenoma Formation. ENDOCRINE REVIEWS. vol. 35,
Radian S, Gabrovska P, Holland B et al. (2014) . Population Screening for the Irish Founder AIP Mutation R304*Reveals a Prevalence of 1/500 in the Local Population, While High Mutation Frequency Is Present Among Irish Familial and Sporadic Somatotropinoma Patients. ENDOCRINE REVIEWS. vol. 35,
Dworakowska D, Dudka D, Weitsman G et al. (2014) . Simultaneous Targeting PI3K/Akt/mTOR and MEK/RAF/ERK Pathways Results in a Synergistic Anti-Proliferative Effect in an Adrenocortical Carcinoma Model.ENDOCRINE REVIEWS vol. 35, (3)
Soh LM, Druce M, Grossman AB et al. (2014) . Strong Genotype-Phenotype Correlation in Pendred Syndrome Allows Reduced Endocrine Follow-up in Suitable Patients. ENDOCRINE REVIEWS. vol. 35,
Aflorei ED, Korbonits M (2014) . Epidemiology and etiopathogenesis of pituitary adenomas.J Neurooncol vol. 117, (3) 379-394.
10.1007/s11060-013-1354-5
Pernicova I, Korbonits M (2014) . Metformin--mode of action and clinical implications for diabetes and cancer.Nat Rev Endocrinol vol. 10, (3) 143-156.
10.1038/nrendo.2013.256
Stadler M, Tomann L, Storka A et al. (2014) . Effects of smoking cessation on b-cell function, insulin sensitivity, body weight, and appetite.European Journal of Endocrinology vol. 170, (2) 219-227.
10.1530/EJE-13-0590
Stadler M, Krššák M, Jankovic D et al. (2014) . Fasting and postprandial liver glycogen content in patients with type 1 diabetes mellitus after successful pancreas-kidney transplantation with systemic venous insulin delivery.Clin Endocrinol (Oxf) vol. 80, (2) 208-213.
10.1111/cen.12146
Doleschall M, Szabó JA, Pázmándi J et al. (2014) . Common genetic variants of the human steroid 21-hydroxylase gene (CYP21A2) are related to differences in circulating hormone levels.PLoS One vol. 9, (9)
10.1371/journal.pone.0107244
http://qmro.qmul.ac.uk/xmlui/handle/123456789/12716
Alband N, Korbonits M (2014) . Familial pituitary tumors.Handb Clin Neurol vol. 124, 339-360.
10.1016/B978-0-444-59602-4.00023-X
Garcia EA, Trivellin G, Aflorei ED et al. (2013) . Characterization of SNARE proteins in human pituitary adenomas: targeted secretion inhibitors as a new strategy for the treatment of acromegaly?.J Clin Endocrinol Metab vol. 98, (12) E1918-E1926.
10.1210/jc.2013-2602
Kola B, Wittman G, Bodnár I et al. (2013) . The CB1 receptor mediates the peripheral effects of ghrelin on AMPK activity but not on growth hormone release.FASEB J vol. 27, (12) 5112-5121.
10.1096/fj.13-232918
Gadelha MR, Kasuki L, Dénes J et al. (2013) . MicroRNAs: Suggested role in pituitary adenoma pathogenesis.J Endocrinol Invest vol. 36, (10) 889-895.
10.1007/BF03346759
Scerif M, Füzesi T, Thomas JD et al. (2013) . CB1 receptor mediates the effects of glucocorticoids on AMPK activity in the hypothalamus.J Endocrinol vol. 219, (1) 79-88.
10.1530/JOE-13-0192
Rattenberry E, Vialard L, Yeung A et al. (2013) . A Comprehensive Next Generation Sequencing-Based Genetic Testing Strategy To Improve Diagnosis of Inherited Pheochromocytoma and Paraganglioma.JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM vol. 98, (7) E1248-E1256.
10.1210/jc.2013-1319
Gadelha MR, Kasuki L, Korbonits M (2013) . Novel pathway for somatostatin analogs in patients with acromegaly.TRENDS IN ENDOCRINOLOGY AND METABOLISM vol. 24, (5) 238-246.
10.1016/j.tem.2012.11.007
Hernández-Ramírez LC, Korbonits M (2013) . Familial Pituitary Adenomas.Pituitary Disorders: Diagnosis and Management,
Occhi G, Regazzo D, Trivellin G et al. (2013) . A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 Phenotype.PLOS GENETICS vol. 9, (3) Article ARTN e1003350,
10.1371/journal.pgen.1003350
http://qmro.qmul.ac.uk/xmlui/handle/123456789/4902
Javaid MR, Stone I, Grossman A et al. (2013) . CARDIAC MAGNETIC RESONANCE MYOCARDIAL FEATURE TRACKING: THE EFFECT OF TREATMENT IN PATIENTS WITH ADULT-ONSET GROWTH HORMONE DEFICIENCY AND ACROMEGALY. INTERNATIONAL JOURNAL OF CARDIOLOGY. vol. 163, S60-S60.
Lim CT, Kola B, Feltrin D et al. (2013) . Ghrelin and cannabinoids require the ghrelin receptor to affect cellular energy metabolism.Mol Cell Endocrinol vol. 365, (2) 303-308.
10.1016/j.mce.2012.11.007
Kovács GL, Góth M, Rotondo F et al. (2013) . ACTH-secreting Crooke cell carcinoma of the pituitary.Eur J Clin Invest vol. 43, (1) 20-26.
10.1111/eci.12010
Williams F, Hunter S, Bradley L et al. (2013) . Clinical experience in the screening and management of a large kindred with familial isolated pituitary adenoma due to an aryl hydrocarbon receptor interacting protein (AIP) mutation.Journal of Clinical Endocrinology and Metabolism vol. 99, (4) 1122-1131.
10.1210/jc.2013-2868
Gadelha MR, Trivellin G, Hernandez-Ramirez LC et al. (2013) . Genetics of Pituitary Adenomas.ENDOCRINE TUMOR SYNDROMES AND THEIR GENETICS vol. 41, 111-140.
10.1159/000345673
Gueorguiev M, Korbonits M (2013) . Genetics of the ghrelin system.Endocr Dev vol. 25, 25-40.
10.1159/000348665
Martucci F, Trivellin G, Korbonits M (2012) . Familial isolated pituitary adenomas: an emerging clinical entity.J Endocrinol Invest vol. 35, (11) 1003-1014.
10.1007/BF03346742
Guaraldi F, Corazzini V, Gallia GL et al. (2012) . Genetic analysis in a patient presenting with meningioma and familial isolated pituitary adenoma (FIPA) reveals selective involvement of the R81X mutation of the AIP gene in the pathogenesis of the pituitary tumor.Pituitary vol. 15 Suppl 1, S61-S67.
10.1007/s11102-012-0391-y
Boguszewski CL, Fighera TM, Bornschein A et al. (2012) . Genetic studies in a coexistence of acromegaly, pheochromocytoma, gastrointestinal stromal tumor (GIST) and thyroid follicular adenoma.ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA vol. 56, (8) 507-512.
10.1590/S0004-27302012000800008
Nölting S, Garcia E, Alusi G et al. (2012) . Combined blockade of signalling pathways shows marked anti-tumour potential in phaeochromocytoma cell lines.J Mol Endocrinol vol. 49, (2) 79-96.
10.1530/JME-12-0028
Trivellin G, Butz H, Delhove J et al. (2012) . MicroRNA miR-107 is overexpressed in pituitary adenomas and inhibits the expression of aryl hydrocarbon receptor-interacting protein in vitro.Am J Physiol Endocrinol Metab vol. 303, (6) E708-E719.
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Korbonits M, GROSSMAN AB, Hubina E et al. (2005) . Investigation of the intracellular effects of somatostatin analogs in pituitary adenomas.J Clin Endocrinol Metab
Hubina E, Ruscica M, Nanzer AM et al. (2005) . Novel molecular aspects of pituitary adenomas.J Endocrinol Invest vol. 28, (11 Suppl International) 87-92.
KORBONITS MJ, Barnes PJ, Korbonits D et al. (2005) . Theobromine inhibits sensory nerve activation and cough.FASEB J vol. 19, 231-233`.
10.1096/fj.04-1990fje
Korbonits M, Kipnes M, Grossman AB (2004) . Striant (TM) SR: a novel, effective and convenient testosterone therapy for male hypogonadism.INT J CLIN PRACT vol. 58, (11) 1073-1080.
10.1111/j.1368-5031.2004.000383.x
Tucci SA, Rogers EK, Korbonits M et al. (2004) . The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin.BRIT J PHARMACOL vol. 143, (5) 520-523.
10.1038/sj.bjp.0705968
Usmani OS, Belvisi MG, Patel HJ et al. (2004) . Theobromine inhibits sensory nerve activation and cough.FASEB J vol. 18, (14) 231-+.
10.1096/fj.04-1990fje
Nanzer AM, Khalaf S, Mozid AM et al. (2004) . Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.Eur J Endocrinol vol. 151, (2) 233-240.
10.1530/eje.0.1510233
Korbonits M, Grossman AB (2004) . Ghrelin: update on a novel hormonal system.EUR J ENDOCRINOL vol. 151, S67-S70.
10.1530/eje.0.151S067
Gueorguiev M, Lecoeur C, Froguel R et al. (2004) . Mutational analysis of ghrelin and the growth hormone secretagogue receptor. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. vol. 7, S56-S56.
Korbonits M, Slawik M, Cullen D et al. (2004) . A comparison of a novel testosterone bioadhesive buccal system, striant, with a testosterone adhesive patch in hypogonadal males.J Clin Endocrinol Metab vol. 89, (5) 2039-2043.
10.1210/jc.2003-030319
Góth M, Korbonits M (2004) . [Therapy in acromegaly].Orv Hetil vol. 145, (16) 867-871.
Goldstone AP, Thomas EL, Brynes AE et al. (2004) . Elevated fasting plasma ghrelin in prader-willi syndrome adults is not solely explained by their reduced visceral adiposity and insulin resistance.J Clin Endocrinol Metab vol. 89, (4) 1718-1726.
10.1210/jc.2003-031118
Korbonits M, Goldstone AP, Gueorguiev M et al. (2004) . Ghrelin - a hormone with multiple functions.FRONT NEUROENDOCRIN vol. 25, (1) 27-68.
10.1016/j.yfrne.2004.03.002
KORBONITS MJ, Hubina E, Goth MI (2004) . Aetiology and demography of patients with GH deficiency in KIMS.Growth hormone deficiency in Adults - KIMS 10 years Anonymous
Grossman AB, Korbonits M (2004) . Akting and cycling: a tale of the pituitary.Horm Res vol. 62 Suppl 3, 117-123.
10.1159/000080512
Bonner SE, Morris DG, Korbonits M et al. (2004) . Cell cycle dysregulation in breast cancer - the roles of Jab1 and Archipelago. BREAST CANCER RESEARCH AND TREATMENT. vol. 88, S180-S180.
Musat M, Vax VV, Borboli N et al. (2004) . Cell cycle dysregulation in pituitary oncogenesis.FRONT HORM RES vol. 32, 34-62.
10.1159/000079037
Vax V, Goncharov N, Kadashev B et al. (2004) . Gonadotropinomas & non-functioning pituitary tumours in males. PROCEEDINGS OF THE 12TH INTERNATIONAL CONGRESS OF ENDOCRINOLOGY. 413-419.
KORBONITS MJ, Grossman AB (2004) . Non-growth hormone endocrine actions of ghrelin.Ghrelin and growth hormone secretagogues73-88.
Korbonits M, Morris DG, Nanzer A et al. (2004) . Role of regulatory factors in pituitary tumour formation.Front Horm Res vol. 32, 63-95.
10.1159/000079038
Morris DG, Kola B, Borboli N et al. (2003) . Identification of adrenocorticotropin receptor messenger ribonucleic acid in the human pituitary and its loss of expression in pituitary adenomas.J Clin Endocrinol Metab vol. 88, (12) 6080-6087.
10.1210/jc.2002-022048
Kola B, Korbonits M, Diaz-Cano S et al. (2003) . Reduced expression of the growth hormone and type 1 insulin-like growth factor receptors in human somatotroph tumours and an analysis of possible mutations of the growth hormone receptor.Clin Endocrinol (Oxf) vol. 59, (3) 328-338.
10.1046/j.1365-2265.2003.01851.x
Vax VV, Gueorguiev M, Dedov II et al. (2003) . The Krüppel-like transcription factor 6 gene in sporadic pituitary tumours.Endocr Relat Cancer vol. 10, (3) 397-402.
10.1677/erc.0.0100397
Vax VV, Bibi R, Diaz-Cano S et al. (2003) . Activating point mutations in cyclin-dependent kinase 4 are not seen in sporadic pituitary adenomas, insulinomas or Leydig cell tumours.J Endocrinol vol. 178, (2) 301-310.
10.1677/joe.0.1780301
Mozid AM, Tringali G, Forsling ML et al. (2003) . Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin.Horm Metab Res vol. 35, (8) 455-459.
10.1055/s-2003-41801
Orkin RD, New DI, Norman D et al. (2003) . Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro.J ENDOCRINOL INVEST vol. 26, (8) 743-747.
10.1007/BF03347357
Svensson J, Monson JP, Vetter T et al. (2003) . Oral administration of the growth hormone secretagogue NN703 in adult patients with growth hormone deficiency.CLIN ENDOCRINOL vol. 58, (5) 572-580.
10.1046/j.1365-2265.2003.01754.x
KORBONITS MJ, Grossman AB, Kola B et al. (2003) . Expression of the F-box protein Skp-2 in normal and tumorous pituitary.Pituitary vol. 5, 235-242.
KORBONITS MJ, Grossman AB, Bandeira F et al. (2003) . Hyperprolactinaemia.Endocrinology and Diabetes105-116.
Pyle ME, Korbonits M, Gueorguiev M et al. (2003) . Macrophage migration inhibitory factor expression is increased in pituitary adenoma cell nuclei.J Endocrinol vol. 176, (1) 103-110.
10.1677/joe.0.1760103
Kaltsas GA, Kola B, Borboli N et al. (2002) . Sequence analysis of the PRKAR1A gene in sporadic somatotroph and other pituitary tumours.Clin Endocrinol (Oxf) vol. 57, (4) 443-448.
10.1046/j.1365-2265.2002.01643.x
Korbonits M, Gueorguiev M, O'Grady E et al. (2002) . A variation in the ghrelin gene increases weight and decreases insulin secretion in tall, obese children.J Clin Endocrinol Metab vol. 87, (8) 4005-4008.
10.1210/jcem.87.8.8881
Gueorguiev M, Korbonits M, O'Grady E et al. (2002) . Mutation in the ghrelin gene associated with increase in body weight and reduction of insulin secretion in tall, obese children. DIABETOLOGIA. vol. 45, A176-A176.
Korbonits M, Chahal HS, Kaltsas G et al. (2002) . Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors.J Clin Endocrinol Metab vol. 87, (6) 2635-2643.
10.1210/jcem.87.6.8517
Gnanapavan S, Kola B, Bustin SA et al. (2002) . The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans.J CLIN ENDOCR METAB vol. 87, (6) 2988-2991.
10.1210/jcem.87.6.8739
Newell-Price J, Morris DG, Drake WM et al. (2002) . Optimal response criteria for the human CRH test in the differential diagnosis of ACTH-dependent Cushing's syndrome.J CLIN ENDOCR METAB vol. 87, (4) 1640-1645.
10.1210/jcem.87.4.8357
Isidori AM, Kaltsas GA, Korbonits M et al. (2002) . Response of serum macrophage migration inhibitory factor levels to stimulation or suppression of the hypothalamo-pituitary-adrenal axis in normal subjects and patients with Cushing's disease.J Clin Endocrinol Metab vol. 87, (4) 1834-1840.
10.1210/jcem.87.4.8382
Musat M, Korbonits M, Pyle M et al. (2002) . The expression of the F-box protein Skp2 is negatively associated with p27 expression in human pituitary tumors.Pituitary vol. 5, (4) 235-242.
10.1023/A:1025325832698
KORBONITS MJ (2002) . Tumours and Humors.Central and Peripheral Mechanisms in Pituitary Disease vol. 87, 201-218.
Korbonits M, Bujalska I, Shimojo M et al. (2001) . Expression of 11 beta-hydroxysteroid dehydrogenase isoenzymes in the human pituitary: Induction of the type 2 enzyme in corticotropinomas and other pituitary tumors.J CLIN ENDOCR METAB vol. 86, (6) 2728-2733.
10.1210/jcem.86.6.7563
Korbonits M, Chitnis MM, Gueorguiev M et al. (2001) . The release of leptin and its effect on hormone release from human pituitary adenomas.Clin Endocrinol (Oxf) vol. 54, (6) 781-789.
10.1046/j.1365-2265.2001.01279.x
Kaltsas G, Korbonits M, Heintz E et al. (2001) . Comparison of somatostatin analog and meta-iodobenzylguanidine radionuclides in the diagnosis and localization of advanced neuroendocrine tumors.J CLIN ENDOCR METAB vol. 86, (2) 895-902.
10.1210/jcem.86.2.7194
Korbonits M, Kojima M, Kangawa K et al. (2001) . Presence of ghrelin in normal and adenomatous human pituitary.Endocrine vol. 14, (1) 101-104.
10.1385/ENDO:14:1:101
Korbonits M, Bustin SA, Kojima M et al. (2001) . The expression of the growth hormone secretagogue receptor ligand ghrelin in normal and abnormal human pituitary and other neuroendocrine tumors.J Clin Endocrinol Metab vol. 86, (2) 881-887.
10.1210/jcem.86.2.7190
KORBONITS MJ, Grossman AB, Bonthron DT et al. (2001) . Imprinting of the G(s)alpha gene GNAS1 in the pathogenesis of acromegaly.J Clin Invest vol. 107, R31-R36.
10.1172/JCI11887
KORBONITS MJ, Gueorguiev M, Goth MI (2001) . Leptin and puberty - a review.Pituitary vol. 4, (1-2) 79-86.
10.1023/A:1012943029127
Korbonits M, Chitnis MM, Gueorguiev M et al. (2001) . Leptin in pituitary adenomas--a novel paracrine regulatory system.Pituitary vol. 4, (1-2) 49-55.
10.1023/a:1012934710471
Kaltsas GA, Korbonits M, Isidori AM et al. (2000) . How common are polycystic ovaries and the polycystic ovarian syndrome in women with Cushing's syndrome?.Clin Endocrinol (Oxf) vol. 53, (4) 493-500.
10.1046/j.1365-2265.2000.01117.x
Putignano P, Kaltsas GA, Korbonits M et al. (2000) . Alterations in serum protein levels in patients with Cushing's syndrome before and after successful treatment.J Clin Endocrinol Metab vol. 85, (9) 3309-3312.
10.1210/jcem.85.9.6833
Jordan S, Lidhar K, Korbonits M et al. (2000) . Cyclin D and cyclin E expression in normal and adenomatous pituitary.Eur J Endocrinol vol. 143, (1) R1-R6.
10.1530/eje.0.143R001
Skelly RH, Korbonits M, Grossman A et al. (2000) . Expression of the pituitary transcription factor Ptx-1, but not that of the trans-activating factor prop-1, is reduced in human corticotroph adenomas and is associated with decreased alpha-subunit secretion.J Clin Endocrinol Metab vol. 85, (7) 2537-2542.
10.1210/jcem.85.7.6683
Korbonits M, Grossman AB (2000) . Drug-induced hyperprolactinaemia.Prescribers' Journal vol. 40, (2) 157-164.
Lidhar K, Korbonits M, Jordan S et al. (1999) . Low expression of the cell cycle inhibitor p27Kip1 in normal corticotroph cells, corticotroph tumors, and malignant pituitary tumors.J Clin Endocrinol Metab vol. 84, (10) 3823-3830.
10.1210/jcem.84.10.6066
Korbonits M, Kaltsas G, Perry LA et al. (1999) . Hexarelin as a test of pituitary reserve in patients with pituitary disease.Clin Endocrinol (Oxf) vol. 51, (3) 369-375.
10.1046/j.1365-2265.1999.00828.x
Korbonits M, Little JA, Forsling ML et al. (1999) . The effect of growth hormone secretagogues and neuropeptide Y on hypothalamic hormone release from acute rat hypothalamic explants.J Neuroendocrinol vol. 11, (7) 521-528.
10.1046/j.1365-2826.1999.00353.x
Korbonits M, Kaltsas G, Perry LA et al. (1999) . The growth hormone secretagogue hexarelin stimulates the hypothalamo-pituitary-adrenal axis via arginine vasopressin.J Clin Endocrinol Metab vol. 84, (7) 2489-2495.
10.1210/jcem.84.7.5811
Satta MA, Korbonits M, Jacobs RA et al. (1999) . Expression of menin gene mRNA in pituitary tumours.Eur J Endocrinol vol. 140, (4) 358-361.
10.1530/eje.0.1400358
Korbonits M, Ciccarelli E, Ghigo E et al. (1999) . The growth hormone secretagogue receptor. Growth Horm IGF Res. vol. 9 Suppl A, 93-99.
10.1016/S1096-6374(99)80019-7
Korbonits M (1998) . Leptin and the thyroid--a puzzle with missing pieces.Clin Endocrinol (Oxf) vol. 49, (5) 569-572.
10.1046/j.1365-2265.1998.00594.x
Korbonits M, Jacobs RA, Aylwin SJ et al. (1998) . Expression of the growth hormone secretagogue receptor in pituitary adenomas and other neuroendocrine tumors.J Clin Endocrinol Metab vol. 83, (10) 3624-3630.
10.1210/jcem.83.10.5210
Trainer PJ, Woods RJ, Korbonits M et al. (1998) . The pathophysiology of circulating corticotropin-releasing hormone-binding protein levels in the human.J Clin Endocrinol Metab vol. 83, (5) 1611-1614.
10.1210/jcem.83.5.4751
Korbonits M, Trainer PJ, Little JA et al. (1997) . Leptin levels do not change acutely with food administration in normal or obese subjects, but are negatively correlated with pituitary-adrenal activity.Clin Endocrinol (Oxf) vol. 46, (6) 751-757.
10.1046/j.1365-2265.1997.1820979.x
Korbonits M, Trainer PJ, Nelson ML et al. (1996) . Differential stimulation of cortisol and dehydroepiandrosterone levels by food in obese and normal subjects: relation to body fat distribution.Clin Endocrinol (Oxf) vol. 45, (6) 699-706.
10.1046/j.1365-2265.1996.8550865.x
Korbonits M, Grossman AB (1996) . [Growth hormone-releasing peptides (GHRP) and their analogues].Orv Hetil vol. 137, (45) 2503-2509.
Korbonits M, Trainer PJ, Fanciulli G et al. (1996) . L-arginine is unlikely to exert neuroendocrine effects in humans via the generation of nitric oxide.Eur J Endocrinol vol. 135, (5) 543-547.
10.1530/eje.0.1350543
Korbonits M, Little JA, Camacho-Hübner C et al. (1996) . Insulin-like growth factor-I and- II in combination inhibit the release of growth hormone-releasing hormone from the rat hypothalamus in vitro.Growth Regul vol. 6, (2) 110-120.
Savage MO, Korbonits M, Grossman AB (1996) . [Clinical value of neuropeptides GHRH and GHRP].Arch Pediatr vol. 3 Suppl 1, 148s-150s.
10.1016/0929-693X(96)86022-2
Korbonits M, Trainer PJ, Besser GM (1995) . The effect of an opiate antagonist on the hormonal changes induced by hexarelin.Clin Endocrinol (Oxf) vol. 43, (3) 365-371.
10.1111/j.1365-2265.1995.tb02045.x
Korbonits M, Trainer PJ, Edwards R et al. (1995) . Benzodiazepines attenuate the pituitary-adrenal responses to corticotrophin-releasing hormone in healthy volunteers, but not in patients with Cushing's syndrome.Clin Endocrinol (Oxf) vol. 43, (1) 29-35.
10.1111/j.1365-2265.1995.tb01889.x
Korbonits M, Grossman AB (1995) . Growth hormone-releasing peptide and its analogues. Novel stimuli to growth hormone release.Trends in Endocrinology and Metabolism vol. 6, (2) 43-49.
10.1016/1043-2760(94)00204-H
Thomas JDJ, Dattani A, Zemrak F et al.. Characterisation of myocardial structure and function in adult-onset growth hormone deficiency using cardiac magnetic resonance.Endocrine
10.1007/s12020-016-1067-6
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15985
Yelamanchi SD, Solanki HS, Radhakrishnan A et al.. Signaling network map of the aryl hydrocarbon receptor.Journal of Cell Communication and Signaling
10.1007/s12079-016-0341-y
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15021
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