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Publications:  Dr Robert Janes

Janes RW (2017) . PDB2CD visualises dynamics within protein structures.Eur Biophys J vol. 46, (7) 607-616.
10.1007/s00249-017-1203-0
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23354
Whitmore L, Mavridis L, Wallace BA et al. (2017) . DichroMatch at the protein circular dichroism data bank (DM@PCDDB): A web-based tool for identifying protein nearest neighbors using circular dichroism spectroscopy.Protein Sci
10.1002/pro.3207
Woollett B, Whitmore L, Janes RW et al. (2013) . ValiDichro: a website for validating and quality control of protein circular dichroism spectra.Nucleic Acids Res vol. 41, (Web Server issue) W417-W421.
10.1093/nar/gkt287
Whitmore L, Woollett B, Janes RW et al. (2013) . The Protein Circular Dichroism Data Bank: A Resource for Data Sharing. BIOPHYSICAL JOURNAL. vol. 104, 567A-567A.
Janes RW, Miles AJ, Woollett B et al. (2012) . Circular dichroism spectral data and metadata in the Protein Circular Dichroism Data Bank (PCDDB): a tutorial guide to accession and deposition.Chirality vol. 24, (9) 751-763.
10.1002/chir.22050
Klose DP, Wallace BA, Janes RW (2012) . DichroMatch: a website for similarity searching of circular dichroism spectra.Nucleic Acids Res vol. 40, (Web Server issue) W547-W552.
10.1093/nar/gks449
Woollett B, Klose D, Cammack R et al. (2012) . JCAMP-DX for circular dichroism spectra and metadata (IUPAC Recommendations 2012).PURE AND APPLIED CHEMISTRY vol. 84, (10) 2171-2182.
10.1351/PAC-REC-12-02-03
Wallace BA, Gekko K, Vronning Hoffmann S et al. (2011) . Synchrotron radiation circular dichroism (SRCD) spectroscopy: An emerging method in structural biology for examining protein conformations and protein interactions. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT. vol. 649, 177-178.
10.1016/j.nima.2010.10.135
Woollett B, Whitmore L, Miles AJ et al. (2011) . Validichro, a Software Tool for Validation of Circular Dichroism (CD) Spectroscopic Data. BIOPHYSICAL JOURNAL. vol. 100, 320-320.
Whitmore L, Woollett B, Miles AJ et al. (2011) . PCDDB: the Protein Circular Dichroism Data Bank, a repository for circular dichroism spectral and metadata.Nucleic Acids Res vol. 39, (Database issue) D480-D486.
10.1093/nar/gkq1026
Klose DP, Wallace BA, Janes RW (2010) . 2Struc: the secondary structure server.Bioinformatics vol. 26, (20) 2624-2625.
10.1093/bioinformatics/btq480
Whitmore L, Woollett B, Miles AJ et al. (2010) . The protein circular dichroism data bank, a Web-based site for access to circular dichroism spectroscopic data.Structure vol. 18, (10) 1267-1269.
10.1016/j.str.2010.08.008
Wallace BA, Janes RW (2010) . Synchrotron radiation circular dichroism (SRCD) spectroscopy: an enhanced method for examining protein conformations and protein interactions.Biochem Soc Trans vol. 38, (4) 861-873.
10.1042/BST0380861
Klose DP, Janes RW (2010) . 2 degrees Struc - the Protein Secondary Structure Analysis Server. BIOPHYSICAL JOURNAL. vol. 98, 454A-455A.
Whitmore L, Woollett B, Miles AJ et al. (2010) . The Protein Circular Dichroism Data Bank (PCDDB) - First Release of a New Resource for Spectroscopic Data Sharing. BIOPHYSICAL JOURNAL. vol. 98, 196A-197A.
Janes RW, Wallace BA (2009) . An introduction to circular dichroism and synchrotron radiation circular dichroism spectroscopy.
Janes RW (2009) . Reference datasets for protein circular dichroism and synchrotron radiation circular dichroism spectroscopic analyses.Advances in Biomedical Spectroscopy vol. 1, 183-201.
10.3233/978-1-60750-000-1-183
Wallace BA, Whitmore L, Janes RW (2009) . The protein circular dichroism data bank (PCDDB): A resource for data archiving, sharing, validation and analysis.Advances in Biomedical Spectroscopy vol. 1, 216-227.
10.3233/978-1-60750-000-1-216
Janes RW (2009) . The pet.NATURE vol. 461, (7261) 304-304.
10.1038/461304a
Miles AJ, Janes RW, Brown A et al. (2008) . Light flux density threshold at which protein denaturation is induced by synchrotron radiation circular dichroism beamlines.J Synchrotron Radiat vol. 15, (Pt 4) 420-422.
10.1107/S0909049508009606
Lees JG, Janes RW (2008) . Combining sequence-based prediction methods and circular dichroism and infrared spectroscopic data to improve protein secondary structure determinations.BMC BIOINFORMATICS vol. 9, Article 24,
10.1186/1471-2105-9-24
Maytum R, Janes RW (2007) . Synchrotron Radiation Circular Dichroism spectroscopy reveals a new structural transition in tropomyosin. BIOPHYSICAL JOURNAL. 362A-362A.
Miles AJ, Hoffmann SV, Tao Y et al. (2007) . Synchrotron radiation circular dichroism (SRCD) spectroscopy: New beamlines and new applications in biology.SPECTROSC-INT J vol. 21, (5-6) 245-255.
10.1155/2007/282713
Lees JG, Miles AJ, Janes RW et al. (2006) . Novel methods for secondary structure determination using low wavelength (VUV) circular dichroism spectroscopic data.BMC Bioinformatics vol. 7,
10.1186/1471-2105-7-507
Cuff AL, Janes RW, Martin ACR (2006) . Analysing the ability to retain sidechain hydrogen-bonds in mutant proteins.Bioinformatics vol. 22, (12) 1464-1470.
10.1093/bioinformatics/btl120
Whitmore L, Janes RW, Wallace BA (2006) . Protein Circular Dichroism Data Bank (PCDDB): data bank and website design.Chirality vol. 18, (6) 426-429.
10.1002/chir.20267
JANES RW, Lees JG, Miles AJ et al. (2006) . A Circular Dichroism Reference Database for Membrane Proteins.Biophysical Journal vol. 90,
Wallace BA, Whitmore L, Janes RW (2006) . The Protein Circular Dichroism Data Bank (PCDDB): A bioinformatics and spectroscopic resource.PROTEINS vol. 62, (1) 1-3.
10.1002/prot.20676
Janes RW (2005) . Bioinformatics analyses of circular dichroism protein reference databases.Bioinformatics vol. 21, (23) 4230-4238.
10.1093/bioinformatics/bti690
Janes RW, Cuff AL (2005) . Overcoming protein denaturation caused by irradiation in a high-flux synchrotron radiation circular dichroism beamline.J Synchrotron Radiat vol. 12, (Pt 4) 524-529.
10.1107/S0909049505007703
Janes RW, O'Boyle F, Mezo G et al. (2005) . Structural investigations of alpha-Conotoxin SI chimeras containing epitopes from Herpes Simplex Virus and cancer-related Mucin proteins reveal notable conformational differences. FEBS JOURNAL. vol. 272, 526-526.
Janes RW (2005) . alpha-Conotoxins as selective probes for nicotinic acetylcholine receptor subclasses.Curr Opin Pharmacol vol. 5, (3) 280-292.
10.1016/j.coph.2005.01.013
Hawkes NJ, Janes RW, Hemingway J et al. (2005) . Detection of resistance-associated point mutations of organophosphate-insensitive acetylcholinesterase in the olive fruit fly, Bactrocera oleae (Gmelin).PESTIC BIOCHEM PHYS vol. 81, (3) 154-163.
10.1016/j.pestbp.2004.11.003
Wien F, Miles AJ, Lees JG et al. (2005) . A new circular dichroism spectroscopy reference dataset covering fold space. BIOPHYSICAL JOURNAL. vol. 88, 554A-554A.
JANES RW, Wallace BA (2005) . Meeting Reports: International Workshop on the Protein Circular Dichroism Data Bank.Synchrotron Radiation News vol. 18, (4) 20-21.
Miles AJ, Wien F, Lees JG et al. (2004) . A method for calibration and standardisation of synchrotron radiation circular dichroism (SRCD) and conventional circular dichroism spectrophotometers and its applications to protein secondary structure analyses. BIOPHYSICAL JOURNAL. vol. 86, 358A-358A.
Wallace BA, Janes RW (2003) . Circular dichroism and synchrotron radiation circular dichroism spectroscopy: tools for drug discovery (vol 31, pg 631, 2003).BIOCHEM SOC T vol. 31, 1531-1531.
10.1042/bst0311531
Wallace BA, Janes RW (2003) . Erratum: Circular dichroism and synchrotron radiation circular dichroism spectroscopy - Tools for drug discovery (Biochemical Society Transactions (2003) 31:3 (631-633)).Biochemical Society Transactions vol. 31, (6)
Vontas JG, Hejazi MJ, Hawkes NJ et al. (2003) . Erratum: Resistance-associated point mutations of organophosphate insensitive acetylcholinesterase, in the olive fruit fly Bactrocera oleae (Insect Molecular Biology (2002) 11 (329-336)).Insect Molecular Biology vol. 12, (4)
10.1046/j.1365-2583.2003.00434.x
Vontas JG, Hejazi MJ, Hawkes NJ et al. (2003) . Resistance-associated point mutations of organophosphate insensitive acetylcholinesterase, in the olive fruit fly Bactrocera oleae (vol 11, pg 329, 2002).INSECT MOL BIOL vol. 12, (4) 413-413.
Wallace BA, Janes RW (2003) . Circular dichroism and synchrotron radiation circular dichroism spectroscopy: tools for drug discovery.BIOCHEM SOC T vol. 31, 631-633.
10.1042/BST0310631
Janes RW (2003) . Nicotinic acetylcholine receptors: alpha-conotoxins as templates for rational drug design.BIOCHEM SOC T vol. 31, 634-636.
10.1042/BST0310634
Wallace BA, Lees JG, Orry AJW et al. (2003) . Analyses of circular dichroism spectra of membrane proteins.Protein Sci vol. 12, (4) 875-884.
10.1110/ps.0229603
Wallace BA, Lees JG, Orry A et al. (2003) . Circular dichroism analyses of membrane proteins. BIOPHYSICAL JOURNAL. vol. 84, 136A-136A.
Miles AJ, Wien F, Lees JG et al. (2003) . Calibration and standardisation of synchrotron radiation circular dichroism and conventional circular dichroism spectrophotometers.SPECTROSC-INT J vol. 17, (4) 653-661.
10.1155/2003/379137
Vontas JG, Hejazi MJ, Hawkes NJ et al. (2002) . Resistance-associated point mutations of organophosphate insensitive acetylcholinesterase, in the olive fruit fly Bactrocera oleae.Insect Mol Biol vol. 11, (4) 329-336.
10.1046/j.1365-2583.2002.00343.x
Wallace BA, Lees J, Janes RW (2002) . Fold recognition by Synchrotron Radiation Circular Dichroism (SRCD) spectroscopy: A new tool for structural genomics.BIOPHYS J vol. 82, (1) 360A-360A.
Wallace BA, Janes RW (2001) . Synchrotron radiation circular dichroism spectroscopy of proteins: secondary structure, fold recognition and structural genomics.CURR OPIN CHEM BIOL vol. 5, (5) 567-571.
10.1016/S1367-5931(00)00243-X
Orry AJW, Janes RW, Sarra R et al. (2001) . Synchrotron radiation circular dichroism spectroscopy: vacuum ultraviolet irradiation does not damage protein integrity.J SYNCHROTRON RADIAT vol. 8, 1027-1029.
10.1107/S0909049501004496
Janes RW, Potter BS, Naylor MA et al. (2001) . 1-Methylindole-3-carboxaldehyde oxime derivatives.ACTA CRYSTALLOGR C vol. 57, 58-61.
10.1107/S0108270100005795
Wallace BA, Janes RW, Orry A (2001) . Secondary structure information content on the VUV region of synchrotron radiation circular dichroism (SRCD) spectra.BIOPHYS J vol. 80, (1) 28A-28A.
Benie AJ, Whitford D, Hargittai B et al. (2000) . Solution structure of alpha-conotoxin SI.FEBS Lett vol. 476, (3) 287-295.
10.1016/S0014-5793(00)01724-5
Janes RW (2000) . 1-[5-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl]guanidinium chloride.Acta Crystallogr C vol. 56 ( Pt 4), 508-509.
10.1107/S0108270100001669
Janes RW (2000) . 3,5-Diamino-6-(2-fluorophenyl)-1,2,4-triazine-dimethylformamide (1/1).Acta Crystallographica Section C: Crystal Structure Communications vol. 56, (3) 362-364.
Janes RW (2000) . 3,5-diamino-6-(2-fluorophenyl)-1,2,4-triazine-dimethylformamide (1/1).Acta Crystallogr C vol. 56 ( Pt 3), 362-364.
10.1107/S0108270199015607
Janes RW (2000) . 1-{5-[2-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl}guanidinium chloride.Acta Crystallographica Section C: Crystal Structure Communications vol. 56, (4) 508-509.
Janes RW (1999) . Crystal structure of an analog of the anticonvulsant lamotrigine, 3,5-diamino-6-(2,3,5-trichlorophenyl)-1,2,4-triazine · dimethanolate, and structure comparisons with related analogs.Journal of Chemical Crystallography vol. 29, (2) 163-167.
Rodi DJ, Janes RW, Sanganee HJ et al. (1999) . Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein.J Mol Biol vol. 285, (1) 197-203.
10.1006/jmbi.1998.2303
Wallace BA, Janes RW (1999) . Tryptophans in membrane proteins. X-ray crystallographic analyses. Adv Exp Med Biol. vol. 467, 789-799.
Janes RW, Munroe PB, Mitchison HM et al. (1996) . A model for Batten disease protein CLN3: functional implications from homology and mutations.FEBS Lett vol. 399, (1-2) 75-77.
10.1016/S0014-5793(96)01290-2
Janes RW, Palmer RA (1996) . 3,5-Diamino-6-(2-bromophenyl)-1,2,4-triazine dimethanol solvate: An analogue of lamotrigine.Acta Crystallographica Section C: Crystal Structure Communications vol. 52, (10) 2627-2629.
10.1107/S010827019501300X
Peto H, Corder R, Janes RW et al. (1996) . A molecular model for human Big-Endothelin-1 (Big ET-1).FEBS Lett vol. 394, (2) 191-195.
10.1016/0014-5793(96)00951-9
Peishoff CE, Janes RW, Wallace BA (1995) . Comparison of the structures of the endothelin A receptor antagonists BQ123 and N-methyl leucine BQ123 with the crystal structure of the C-terminal tail of endothelin-1.FEBS Lett vol. 374, (3) 379-383.
10.1016/0014-5793(95)01156-9
Janes RW, Palmer RA (1995) . Practical limitations observed using the AM1, MNDO and MINDO/3 semi-empirical methods for charge calculation and structure optimization in 1,2,4-triazine ring-containing compounds.Journal of Molecular Structure: THEOCHEM vol. 339, (1-3) 95-101.
10.1016/0166-1280(95)04141-R
Lapthorn AJ, Janes RW, Isaacs NW et al. (1995) . Cystine nooses and protein specificity.Nat Struct Biol vol. 2, (4) 266-268.
10.1038/nsb0495-266
Wallace BA, Janes RW, Bassolino DA et al. (1995) . A comparison of X-ray and NMR structures for human endothelin-1.Protein Sci vol. 4, (1) 75-83.
10.1002/pro.5560040110
Wallace BA, Janes RW (1995) . The crystal structure of human endothelin-1 and how it relates to receptor binding.J Cardiovasc Pharmacol vol. 26 Suppl 3, S250-S253.
Janes RW, Wallace BA (1994) . Modelling the structures of the isoforms of human endothelins based on the crystal structure of human endothelin-I. Biochem Soc Trans. vol. 22, 1037-1043.
10.1042/bst0221037
Janes RW, Peapus DH, Wallace BA (1994) . The crystal structure of human endothelin.Nat Struct Biol vol. 1, (5) 311-319.
10.1038/nsb0594-311
Peapus DH, Janes RW, Wallace BA (1993) . Preliminary crystallization and X-ray analysis of orthorhombic human endothelin.J Mol Biol vol. 234, (4) 1250-1252.
10.1006/jmbi.1993.1675
Wood SP, Janes RW, Sweeney E et al. (1992) . Crystallization of bovine pancreatic polypeptide in the presence of crystalline diglycidyl ether of bisphenol A (Araldite): epitaxy or covalent nucleation?.Journal of Crystal Growth vol. 122, (1-4) 204-207.
10.1016/0022-0248(92)90246-F
Wallace BA, Janes RW (1991) . Co-crystals of gramicidin A and phospholipid. A system for studying the structure of a transmembrane channel.J Mol Biol vol. 217, (4) 625-627.
10.1016/0022-2836(91)90520-G
Whitmore L, Miles AJ, Mavridis L et al.. PCDDB: new developments at the Protein Circular Dichroism Data Bank.Nucleic Acids Research
10.1093/nar/gkw796
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15353
Mavridis L, Janes RW. PDB2CD: A web-based application for the generation of circular dichroism spectra from protein atomic coordinates.Bioinformatics
10.1093/bioinformatics/btw554
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23355
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