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Publications:  Dr Robert Janes

Whitmore L, Mavridis L, Wallace BA et al.(2018). DichroMatch at the protein circular dichroism data bank (DM@PCDDB): A web-based tool for identifying protein nearest neighbors using circular dichroism spectroscopy. Protein Sci vol. 27, (1) 10-13.
10.1002/pro.3207
Janes RW(2017). PDB2CD visualises dynamics within protein structures. Eur Biophys J vol. 46, (7) 607-616.
10.1007/s00249-017-1203-0
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23354
Mavridis L, Janes RW(2016). PDB2CD: A web-based application for the generation of circular dichroism spectra from protein atomic coordinates. Bioinformatics
10.1093/bioinformatics/btw554
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23355
Whitmore L, Miles AJ, Mavridis L et al.(2016). PCDDB: new developments at the Protein Circular Dichroism Data Bank. Nucleic Acids Research
10.1093/nar/gkw796
http://qmro.qmul.ac.uk/xmlui/handle/123456789/15353
Woollett B, Whitmore L, Janes RW et al.(2013). ValiDichro: a website for validating and quality control of protein circular dichroism spectra. Nucleic Acids Res vol. 41, (Web Server issue) W417-W421.
10.1093/nar/gkt287
Whitmore L, Woollett B, Janes RW et al. (2013). The Protein Circular Dichroism Data Bank: A Resource for Data Sharing. BIOPHYSICAL JOURNAL. vol. 104, 567A-567A.
10.1016/j.bpj.2012.11.3148
Janes RW, Miles AJ, Woollett B et al.(2012). Circular dichroism spectral data and metadata in the Protein Circular Dichroism Data Bank (PCDDB): a tutorial guide to accession and deposition. Chirality vol. 24, (9) 751-763.
10.1002/chir.22050
Klose DP, Wallace BA, Janes RW(2012). DichroMatch: a website for similarity searching of circular dichroism spectra. Nucleic Acids Res vol. 40, (Web Server issue) W547-W552.
10.1093/nar/gks449
Woollett B, Klose D, Cammack R et al.(2012). JCAMP-DX for circular dichroism spectra and metadata (IUPAC Recommendations 2012). PURE AND APPLIED CHEMISTRY vol. 84, (10) 2171-2182.
10.1351/PAC-REC-12-02-03
Wallace BA, Gekko K, Vronning Hoffmann S et al. (2011). Synchrotron radiation circular dichroism (SRCD) spectroscopy: An emerging method in structural biology for examining protein conformations and protein interactions. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT. vol. 649, 177-178.
10.1016/j.nima.2010.10.135
Woollett B, Whitmore L, Miles AJ et al. (2011). Validichro, a Software Tool for Validation of Circular Dichroism (CD) Spectroscopic Data. BIOPHYSICAL JOURNAL. vol. 100, 320-320.
Whitmore L, Woollett B, Miles AJ et al.(2011). PCDDB: the Protein Circular Dichroism Data Bank, a repository for circular dichroism spectral and metadata. Nucleic Acids Res vol. 39, (Database issue) D480-D486.
10.1093/nar/gkq1026
Klose DP, Wallace BA, Janes RW(2010). 2Struc: the secondary structure server. Bioinformatics vol. 26, (20) 2624-2625.
10.1093/bioinformatics/btq480
Whitmore L, Woollett B, Miles AJ et al.(2010). The protein circular dichroism data bank, a Web-based site for access to circular dichroism spectroscopic data. Structure vol. 18, (10) 1267-1269.
10.1016/j.str.2010.08.008
Wallace BA, Janes RW(2010). Synchrotron radiation circular dichroism (SRCD) spectroscopy: an enhanced method for examining protein conformations and protein interactions. Biochem Soc Trans vol. 38, (4) 861-873.
10.1042/BST0380861
Klose DP, Janes RW (2010). 2 degrees Struc - the Protein Secondary Structure Analysis Server. BIOPHYSICAL JOURNAL. vol. 98, 454A-455A.
10.1016/j.bpj.2009.12.2470
Whitmore L, Woollett B, Miles AJ et al. (2010). The Protein Circular Dichroism Data Bank (PCDDB) - First Release of a New Resource for Spectroscopic Data Sharing. BIOPHYSICAL JOURNAL. vol. 98, 196A-197A.
10.1016/j.bpj.2009.12.1045
Janes RW, Wallace BA(2009). An introduction to circular dichroism and synchrotron radiation circular dichroism spectroscopy.
Janes RW(2009). Reference datasets for protein circular dichroism and synchrotron radiation circular dichroism spectroscopic analyses. Advances in Biomedical Spectroscopy vol. 1, 183-201.
10.3233/978-1-60750-000-1-183
Wallace BA, Whitmore L, Janes RW(2009). The protein circular dichroism data bank (PCDDB): A resource for data archiving, sharing, validation and analysis. Advances in Biomedical Spectroscopy vol. 1, 216-227.
10.3233/978-1-60750-000-1-216
Janes RW(2009). The pet. NATURE vol. 461, (7261) 304-304.
10.1038/461304a
Miles AJ, Janes RW, Brown A et al.(2008). Light flux density threshold at which protein denaturation is induced by synchrotron radiation circular dichroism beamlines. J Synchrotron Radiat vol. 15, (Pt 4) 420-422.
10.1107/S0909049508009606
Lees JG, Janes RW(2008). Combining sequence-based prediction methods and circular dichroism and infrared spectroscopic data to improve protein secondary structure determinations. BMC BIOINFORMATICS vol. 9, Article 24,
10.1186/1471-2105-9-24
Maytum R, Janes RW (2007). Synchrotron Radiation Circular Dichroism spectroscopy reveals a new structural transition in tropomyosin. BIOPHYSICAL JOURNAL. 362A-362A.
Miles AJ, Hoffmann SV, Tao Y et al.(2007). Synchrotron radiation circular dichroism (SRCD) spectroscopy: New beamlines and new applications in biology. SPECTROSC-INT J vol. 21, (5-6) 245-255.
10.1155/2007/282713
Lees JG, Miles AJ, Janes RW et al.(2006). Novel methods for secondary structure determination using low wavelength (VUV) circular dichroism spectroscopic data. BMC Bioinformatics vol. 7,
10.1186/1471-2105-7-507
Cuff AL, Janes RW, Martin ACR(2006). Analysing the ability to retain sidechain hydrogen-bonds in mutant proteins. Bioinformatics vol. 22, (12) 1464-1470.
10.1093/bioinformatics/btl120
Whitmore L, Janes RW, Wallace BA(2006). Protein Circular Dichroism Data Bank (PCDDB): data bank and website design. Chirality vol. 18, (6) 426-429.
10.1002/chir.20267
JANES RW, Lees JG, Miles AJ et al.(2006). A Circular Dichroism Reference Database for Membrane Proteins. Biophysical Journal vol. 90,
Wallace BA, Whitmore L, Janes RW(2006). The Protein Circular Dichroism Data Bank (PCDDB): A bioinformatics and spectroscopic resource. PROTEINS vol. 62, (1) 1-3.
10.1002/prot.20676
Janes RW(2005). Bioinformatics analyses of circular dichroism protein reference databases. Bioinformatics vol. 21, (23) 4230-4238.
10.1093/bioinformatics/bti690
Janes RW, Cuff AL(2005). Overcoming protein denaturation caused by irradiation in a high-flux synchrotron radiation circular dichroism beamline. J Synchrotron Radiat vol. 12, (Pt 4) 524-529.
10.1107/S0909049505007703
Janes RW, O'Boyle F, Mezo G et al. (2005). Structural investigations of alpha-Conotoxin SI chimeras containing epitopes from Herpes Simplex Virus and cancer-related Mucin proteins reveal notable conformational differences. FEBS JOURNAL. vol. 272, 526-526.
Janes RW(2005). alpha-Conotoxins as selective probes for nicotinic acetylcholine receptor subclasses. Curr Opin Pharmacol vol. 5, (3) 280-292.
10.1016/j.coph.2005.01.013
Hawkes NJ, Janes RW, Hemingway J et al.(2005). Detection of resistance-associated point mutations of organophosphate-insensitive acetylcholinesterase in the olive fruit fly, Bactrocera oleae (Gmelin). PESTIC BIOCHEM PHYS vol. 81, (3) 154-163.
10.1016/j.pestbp.2004.11.003
Wien F, Miles AJ, Lees JG et al. (2005). A new circular dichroism spectroscopy reference dataset covering fold space. BIOPHYSICAL JOURNAL. vol. 88, 554A-554A.
JANES RW, Wallace BA(2005). Meeting Reports: International Workshop on the Protein Circular Dichroism Data Bank. Synchrotron Radiation News vol. 18, (4) 20-21.
Miles AJ, Wien F, Lees JG et al. (2004). A method for calibration and standardisation of synchrotron radiation circular dichroism (SRCD) and conventional circular dichroism spectrophotometers and its applications to protein secondary structure analyses. BIOPHYSICAL JOURNAL. vol. 86, 358A-358A.
Wallace BA, Janes RW(2003). Circular dichroism and synchrotron radiation circular dichroism spectroscopy: tools for drug discovery (vol 31, pg 631, 2003). BIOCHEM SOC T vol. 31, 1531-1531.
10.1042/bst0311531
Wallace BA, Janes RW(2003). Erratum: Circular dichroism and synchrotron radiation circular dichroism spectroscopy - Tools for drug discovery (Biochemical Society Transactions (2003) 31:3 (631-633)). Biochemical Society Transactions vol. 31, (6)
Vontas JG, Hejazi MJ, Hawkes NJ et al.(2003). Erratum: Resistance-associated point mutations of organophosphate insensitive acetylcholinesterase, in the olive fruit fly Bactrocera oleae (Insect Molecular Biology (2002) 11 (329-336)). Insect Molecular Biology vol. 12, (4)
10.1046/j.1365-2583.2003.00434.x
Vontas JG, Hejazi MJ, Hawkes NJ et al.(2003). Resistance-associated point mutations of organophosphate insensitive acetylcholinesterase, in the olive fruit fly Bactrocera oleae (vol 11, pg 329, 2002). INSECT MOL BIOL vol. 12, (4) 413-413.
Wallace BA, Janes RW(2003). Circular dichroism and synchrotron radiation circular dichroism spectroscopy: tools for drug discovery. BIOCHEM SOC T vol. 31, 631-633.
10.1042/BST0310631
Janes RW(2003). Nicotinic acetylcholine receptors: alpha-conotoxins as templates for rational drug design. BIOCHEM SOC T vol. 31, 634-636.
10.1042/BST0310634
Wallace BA, Lees JG, Orry AJW et al.(2003). Analyses of circular dichroism spectra of membrane proteins. Protein Sci vol. 12, (4) 875-884.
10.1110/ps.0229603
Wallace BA, Lees JG, Orry A et al. (2003). Circular dichroism analyses of membrane proteins. BIOPHYSICAL JOURNAL. vol. 84, 136A-136A.
Miles AJ, Wien F, Lees JG et al.(2003). Calibration and standardisation of synchrotron radiation circular dichroism and conventional circular dichroism spectrophotometers. SPECTROSC-INT J vol. 17, (4) 653-661.
10.1155/2003/379137
Vontas JG, Hejazi MJ, Hawkes NJ et al.(2002). Resistance-associated point mutations of organophosphate insensitive acetylcholinesterase, in the olive fruit fly Bactrocera oleae. Insect Mol Biol vol. 11, (4) 329-336.
10.1046/j.1365-2583.2002.00343.x
Wallace BA, Lees J, Janes RW(2002). Fold recognition by Synchrotron Radiation Circular Dichroism (SRCD) spectroscopy: A new tool for structural genomics. BIOPHYS J vol. 82, (1) 360A-360A.
Wallace BA, Janes RW(2001). Synchrotron radiation circular dichroism spectroscopy of proteins: secondary structure, fold recognition and structural genomics. CURR OPIN CHEM BIOL vol. 5, (5) 567-571.
10.1016/S1367-5931(00)00243-X
Orry AJW, Janes RW, Sarra R et al.(2001). Synchrotron radiation circular dichroism spectroscopy: vacuum ultraviolet irradiation does not damage protein integrity. J SYNCHROTRON RADIAT vol. 8, 1027-1029.
10.1107/S0909049501004496
Janes RW, Potter BS, Naylor MA et al.(2001). 1-Methylindole-3-carboxaldehyde oxime derivatives. ACTA CRYSTALLOGR C vol. 57, 58-61.
10.1107/S0108270100005795
Wallace BA, Janes RW, Orry A(2001). Secondary structure information content on the VUV region of synchrotron radiation circular dichroism (SRCD) spectra. BIOPHYS J vol. 80, (1) 28A-28A.
Benie AJ, Whitford D, Hargittai B et al.(2000). Solution structure of alpha-conotoxin SI. FEBS Lett vol. 476, (3) 287-295.
10.1016/S0014-5793(00)01724-5
Janes RW(2000). 1-[5-[2-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl]guanidinium chloride. Acta Crystallogr C vol. 56 ( Pt 4), 508-509.
10.1107/S0108270100001669
Janes RW(2000). 3,5-diamino-6-(2-fluorophenyl)-1,2,4-triazine-dimethylformamide (1/1). Acta Crystallogr C vol. 56 ( Pt 3), 362-364.
10.1107/S0108270199015607
Janes RW(2000). 1-{5-[2-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl}guanidinium chloride. Acta Crystallographica Section C: Crystal Structure Communications vol. 56, (4) 508-509.
10.1107/S0108270100001669
Janes RW(2000). 3,5-Diamino-6-(2-fluorophenyl)-1,2,4-triazine-dimethylformamide (1/1). Acta Crystallographica Section C: Crystal Structure Communications vol. 56, (3) 362-364.
10.1107/S0108270199015607
Rodi DJ, Janes RW, Sanganee HJ et al.(1999). Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein. J Mol Biol vol. 285, (1) 197-203.
10.1006/jmbi.1998.2303
Janes RW(1999). Crystal structure of an analog of the anticonvulsant lamotrigine, 3,5-diamino-6-(2,3,5-trichlorophenyl)-1,2,4-triazine · dimethanolate, and structure comparisons with related analogs. Journal of Chemical Crystallography vol. 29, (2) 163-167.
10.1023/A:1009561825373
Wallace BA, Janes RW (1999). Tryptophans in membrane proteins. X-ray crystallographic analyses. Adv Exp Med Biol. vol. 467, 789-799.
Janes RW, Munroe PB, Mitchison HM et al.(1996). A model for Batten disease protein CLN3: functional implications from homology and mutations. FEBS Lett vol. 399, (1-2) 75-77.
10.1016/S0014-5793(96)01290-2
Janes RW, Palmer RA(1996). 3,5-Diamino-6-(2-bromophenyl)-1,2,4-triazine dimethanol solvate: An analogue of lamotrigine. Acta Crystallographica Section C: Crystal Structure Communications vol. 52, (10) 2627-2629.
10.1107/S010827019501300X
Peto H, Corder R, Janes RW et al.(1996). A molecular model for human Big-Endothelin-1 (Big ET-1). FEBS Lett vol. 394, (2) 191-195.
10.1016/0014-5793(96)00951-9
Peishoff CE, Janes RW, Wallace BA(1995). Comparison of the structures of the endothelin A receptor antagonists BQ123 and N-methyl leucine BQ123 with the crystal structure of the C-terminal tail of endothelin-1. FEBS Lett vol. 374, (3) 379-383.
10.1016/0014-5793(95)01156-9
Janes RW, Palmer RA(1995). Practical limitations observed using the AM1, MNDO and MINDO/3 semi-empirical methods for charge calculation and structure optimization in 1,2,4-triazine ring-containing compounds. Journal of Molecular Structure: THEOCHEM vol. 339, (1-3) 95-101.
10.1016/0166-1280(95)04141-R
Lapthorn AJ, Janes RW, Isaacs NW et al.(1995). Cystine nooses and protein specificity. Nat Struct Biol vol. 2, (4) 266-268.
10.1038/nsb0495-266
Wallace BA, Janes RW, Bassolino DA et al.(1995). A comparison of X-ray and NMR structures for human endothelin-1. Protein Sci vol. 4, (1) 75-83.
10.1002/pro.5560040110
Wallace BA, Janes RW(1995). The crystal structure of human endothelin-1 and how it relates to receptor binding. J Cardiovasc Pharmacol vol. 26 Suppl 3, S250-S253.
Janes RW, Wallace BA (1994). Modelling the structures of the isoforms of human endothelins based on the crystal structure of human endothelin-I. Biochem Soc Trans. vol. 22, 1037-1043.
10.1042/bst0221037
Janes RW, Peapus DH, Wallace BA(1994). The crystal structure of human endothelin. Nat Struct Biol vol. 1, (5) 311-319.
10.1038/nsb0594-311
Peapus DH, Janes RW, Wallace BA(1993). Preliminary crystallization and X-ray analysis of orthorhombic human endothelin. J Mol Biol vol. 234, (4) 1250-1252.
10.1006/jmbi.1993.1675
Wood SP, Janes RW, Sweeney E et al.(1992). Crystallization of bovine pancreatic polypeptide in the presence of crystalline diglycidyl ether of bisphenol A (Araldite): epitaxy or covalent nucleation?. Journal of Crystal Growth vol. 122, (1-4) 204-207.
10.1016/0022-0248(92)90246-F
Wallace BA, Janes RW(1991). Co-crystals of gramicidin A and phospholipid. A system for studying the structure of a transmembrane channel. J Mol Biol vol. 217, (4) 625-627.
10.1016/0022-2836(91)90520-G
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