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Publications:  Prof Atholl Johnston

Couchman L, Frinculescu A, Sobreira C, Shine T, Ramsey J, Hecht M, Kipper K, Holt D et al.(2019). Variability in content and dissolution profiles of MDMA tablets collected in the UK between 2001 and 2018 - A potential risk to users?. Drug Test Anal vol. 11, (8) 1172-1182.
10.1002/dta.2605
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57341
Rahman M, Couchman L, Povstyan V, Bainbridge V, Kipper K, El-Nahhas T, Johnston A, Holt D(2019). Rapid Quantitation of Flecainide in Human Plasma for Therapeutic Drug Monitoring Using Liquid Chromatography and Time-of-Flight Mass Spectrometry. Ther Drug Monit vol. 41, (3) 391-395.
10.1097/FTD.0000000000000586
Odor PM, Cavalier AG, Reynolds ND, Ang KS, Parrington SJ, Xu H, Johnston A, Sage FJ(2019). Safety and Pharmacokinetics of Levobupivacaine Following Fascia Iliaca Compartment Block in Elderly Patients. Drugs Aging vol. 36, (6) 541-548.
10.1007/s40266-019-00652-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57099
JOHNSTON A, Adeloye T, Sahgal O, Puri A, Warrington S, Endo T, Dennison J(2018). Amenamevir: Studies of Potential CYP3A-Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers. Clinical Pharmacology in Drug Development
10.1002/cpdd.586
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44827
JOHNSTON A, Hecht M, Veigure R, Couchman L, Barker CIS, Standing J, Takkis K, Evard H et al.(2018). Utilisation of data below the analytical limit of quantitation in pharmacokinetic analysis and modelling: promoting interdisciplinary debate. Bionalysis
10.4155/bio-2018-0078
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43363
Edmonds ME, Bodansky HJ, Boulton AJM, Chadwick PJ, Dang CN, D'Costa R, Johnston A, Kennon B et al.(2018). Multicenter, randomized controlled, observer-blinded study of a nitric oxide generating treatment in foot ulcers of patients with diabetes-ProNOx1 study. Wound Repair Regen vol. 26, (2) 228-237.
10.1111/wrr.12630
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45003
Dennison J, Puri A, Warrington S, Endo T, Adeloye T, Johnston A(2018). Amenamevir: Studies of Potential CYP2C8- and CYP2B6-Mediated Pharmacokinetic Interactions With Montelukast and Bupropion in Healthy Volunteers. Clinical Pharmacology in Drug Development
10.1002/cpdd.578
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44828
Sawhney V, Brouilette S, Campbell N, Coppen S, Baker V, Hunter R, Dhinoja M, Johnston A et al.(2018). Association of genetic variation in telomere-related SNP and telomerase with ventricular arrhythmias in ischemic cardiomyopathy. Pacing Clin Electrophysiol vol. 41, (3) 261-266.
10.1111/pace.13284
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44809
Kipper K, Barker CIS, Standing JF, Sharland M, Johnston A(2018). Development of a Novel Multipenicillin Assay and Assessment of the Impact of Analyte Degradation: Lessons for Scavenged Sampling in Antimicrobial Pharmacokinetic Study Design. Antimicrob Agents Chemother vol. 62, (1)
10.1128/AAC.01540-17
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28847
JOHNSTON A(2017). On the use of substandard medicines in hematology: an emerging concern in the Middle East and North Africa region. European Journal of Internal Medicine
10.1016/j.ejim.2017.08.003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32147
Stathopoulou T-R, Kouki M, Pypendop BH, Johnston A, Papadimitriou S, Pelligand L(2017). Evaluation of analgesic effect and absorption of buprenorphine after buccal administration in cats with oral disease. J Feline Med Surg1098612X17727234-1098612X17727234.
10.1177/1098612X17727234
https://qmro.qmul.ac.uk/xmlui/handle/123456789/27243
JOHNSTON A, Wolff K, Agombar R, Clatworthy A, Cowan D, Forrest R, Osselton D, Scott Ham M (2017). Expert Panel Review of alternative biological matrices for use as an evidential sample for drug driving. The United Kingdom Department for Transport (Online), report no. RM4825 SB-2988,
https://qmro.qmul.ac.uk/xmlui/handle/123456789/27903
Fisher DL, Plange-Rhule J, Moreton M, Eastwood JB, Kerry SM, Micah F, Johnston A, Cappuccio FP et al.(2016). CYP3A5 as a candidate gene for hypertension: no support from an unselected indigenous West African population. J Hum Hypertens vol. 30, (12) 778-782.
10.1038/jhh.2016.25
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13650
Brixner D, Maniadakis N, Kalo Z, Hu S, Johnston A, Shen J, Wijaya KE (2016). APPLICATION OF MULTI-CRITERIA DECISION ANALYSIS (MCDA) SCORING AS AN HTA METHODOLOGY FOR OFF-PATENT PHARMACEUTICALS (OPP) IN EMERGING MARKETS. vol. 19, is. 7, pp. A815-A815.
10.1016/j.jval.2016.08.663
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44825
De Palma R, Sotto I, Wood EG, Khan NQ, Butler J, Johnston A, Rothman MT, Corder R(2016). Cocoa flavanols reduce N-terminal pro-B-type natriuretic peptide in patients with chronic heart failure. ESC Heart Fail vol. 3, (2) 97-106.
10.1002/ehf2.12077
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18496
Sawhney V, Campbell NG, Brouilette SW, Coppen SR, Harbo M, Baker V, Ikebe C, Shintani Y et al.(2016). Telomere shortening and telomerase activity in ischaemic cardiomyopathy patients - Potential markers of ventricular arrhythmia. Int J Cardiol vol. 207, 157-163.
10.1016/j.ijcard.2016.01.066
El-Nahhas T, Moreton M, Popoola J, Abat S, Johnston A, MacPhee I (2015). Conversion from Immediate to Prolonged Release Tacrolimus Did Not Change Intra-Patient Variability in Renal Transplant Patients. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 15,
Elnahhas T, Lee T, Moreton M, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2015). Influence of CYP3A5 and ABCB1 Genotypes on Pharmacokinetics of Immediate and Prolonged Release Tacrolimus Preparations. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 15,
Elnahhas T, de Jonge E, Lee T, van Zelst B, Popoola J, Ramkhelawon R, van Schaik R, Johnston A et al. (2015). Plasma 4 beta-Hydroxycholesterol Measurement as a Potential Biomarker for CYP3A5 Activity in Informing Tacrolimus Dosing. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 15,
Rull G, Mohd-Zain Z, Shiel J, Lundberg MH, Collier DJ, Johnston A, Warner TD, Corder R(2015). Effects of High Flavanol Dark Chocolate on Cardiovascular Function and Platelet Aggregation. Vascular pharmacology
10.1016/j.vph.2015.02.010
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7566
Johnston A, Holt DW(2014). Substandard drugs: a potential crisis for public health. Br J Clin Pharmacol vol. 78, (2) 218-243.
10.1111/bcp.12298
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12629
Elnahhas T, Moreton M, Lee T, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2014). CYP3A5/ABCB1 Combined Genotype Has Similar Influence On Pharmacokinetics of Immediate and Prolonged Release Tacrolimus in Renal Transplant Recipients. TRANSPLANTATION. vol. 98, 548-548.
Elnahhas T, Moreton M, Lee T, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2014). Impact of CYP3A5 and ABCB1 Genotype On The Pharmacokinetics of Prednisolone in Renal Transplant Recipients. TRANSPLANTATION. vol. 98, 548-549.
10.1097/00007890-201407151-01840
Elnahhas T, Moreton M, Lee T, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2014). CYP3A5/ABCB1 Combined Genotype Has Similar Influence On Pharmacokinetics of Immediate and Prolonged Release Tacrolimus in Renal Transplant Recipients. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 14, 548-548.
Al-Otaibi F, Ghazaly E, Johnston A, Perrett D(2014). Development of HPLC-UV method for rapid and sensitive analysis of topically applied tetracaine: its comparison with a CZE method. Biomed Chromatogr vol. 28, (6) 826-830.
10.1002/bmc.3150
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9729
Elnahhas T, Moreton M, Lee T, McKeown D, Popoola J, Ramkhelawon R, Johnston A, MacPhee I (2014). Impact of CYP3A5 and ABCB1 Genotype On The Pharmacokinetics of Prednisolone in Renal Transplant Recipients. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 14, 548-549.
Jawad H, Bain DS, Dawson H, Crawford K, Johnston A, Tucker A(2014). The effectiveness of a novel neuromuscular electrostimulation method versus intermittent pneumatic compression in enhancing lower limb blood flow. J Vasc Surg Venous Lymphat Disord vol. 2, (2) 160-165.
10.1016/j.jvsv.2013.10.052
Payne-James JJ, Rivers E, Green P, Johnston A(2014). Trends in less-lethal use of force techniques by police services within England and Wales: 2007-2011. Forensic Sci Med Pathol vol. 10, (1) 50-55.
10.1007/s12024-013-9492-9
Wolff K, Johnston A(2014). Cannabis use: a perspective in relation to the proposed UK drug-driving legislation. DRUG TESTING AND ANALYSIS vol. 6, (1-2) 143-154.
10.1002/dta.1588
Archer JRH, Dargan PI, Hudson S, Davies S, Puchnarewicz M, Kicman AT, Ramsey J, Measham F et al.(2014). Taking the Pissoir - a novel and reliable way of knowing what drugs are being used in nightclubs. JOURNAL OF SUBSTANCE USE vol. 19, (1-2) 103-107.
10.3109/14659891.2012.740139
Johnston A(2013). Equivalence and interchangeability of narrow therapeutic index drugs in organ transplantation. EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE vol. 20, (5) 302-307.
10.1136/ejhpharm-2012-000258
Al Ameri M, Tucker A, Johnston A(2013). ECONOMIC EVALUATION OF USING BRANDED TAXOTERE (R) VERSUS. GENERIC DOCETAXEL: BASED ON DECISION TREE MODEL. VALUE IN HEALTH vol. 16, (3) A187-A187.
10.1016/j.jval.2013.03.942
Al Ameri MN, Mohamed W, Makramalla E, Shalhoub B, Tucker A, Johnston A(2013). Renal patients' views on generic prescribing and substitution: example from the United Arab Emirates. EASTERN MEDITERRANEAN HEALTH JOURNAL vol. 19, (4) 373-381.
10.26719/2013.19.4.373
Dargan PI, Davies S, Puchnarewicz M, Johnston A, Wood DM(2013). First reported case in the UK of acute prolonged neuropsychiatric toxicity associated with analytically confirmed recreational use of phenazepam. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY vol. 69, (3) 361-363.
10.1007/s00228-012-1361-z
Handley R, Zelaya FO, Reinders AATS, Marques TR, Mehta MA, O'Gorman R, Alsop DC, Taylor H et al.(2013). Acute effects of single-dose aripiprazole and haloperidol on resting cerebral blood flow (rCBF) in the human brain. HUMAN BRAIN MAPPING vol. 34, (2) 272-282.
10.1002/hbm.21436
de Palma R, Sotto I, Khan NQ, Wood EG, Butler J, Johnston A, Rothman MT, Corder R(2012). High Flavanol Dark Chocolate Reduces NT-proBNP in Patients with Chronic Heart Failure. CIRCULATION vol. 126, (21)
Al Ameri MN, Tucker A, Johnston A(2012). ECONOMIC EVALUATION OF USING BRANDED TAXOTERE (R) VERSUS GENERIC DOCETAXEL: BASED ON DECISION TREE MODEL. VALUE IN HEALTH vol. 15, (7) A416-A417.
10.1016/j.jval.2012.08.1238
Aljohani B, Al Otaibi F, Ghazaly E, Perrett D, Johnston A (2012). Development and validation of a h.p.l.c. method for ciclosporin: its application to measurement of brand and generic versions from different countries. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 1007-1007.
Al Ameri MN, Nayuni N, Kumar A, Perrett D, Tucker A, Johnston A (2012). Differences between the branded and generic solid dosage form medicines: in vitro dissolution testing. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 984-984.
Mendis SVG, Perrett D, Johnston A (2012). Factors influencing ethanol elimination in 20 to 30-year-old European males. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 987-988.
Johnston A, Schick L, van Gelder T(2012). Integrating narrow therapeutic index drug formulations in transplantation. EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE vol. 19, (3) 318-319.
10.1136/ejhpharm-2012-000130
Sathiyayogan N, Watts J, Ravi N, Johnston A (2012). NHS R&D offices - Research and Development or Retard and Delay?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 988-988.
Al Ameri MN, Whittaker C, Mohamed W, Makramalla E, Shalhoub B, Yaqoob M, Tucker A, Johnston A (2012). Patients' views on generic substitution in the United Arab Emirates (UAE): focus on renal patients. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 73, 994-994.
Wood DM, Davies S, Puchnarewicz M, Johnston A, Dargan PI(2012). Acute toxicity associated with the recreational use of the ketamine derivative methoxetamine. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY vol. 68, (5) 853-856.
10.1007/s00228-011-1199-9
Wood DM, Puchnarewicz M, Johnston A, Dargan PI(2012). A case series of individuals with analytically confirmed acute diphenyl-2-pyrrolidinemethanol (D2PM) toxicity. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY vol. 68, (4) 349-353.
10.1007/s00228-011-1142-0
Dargan PI, Davies S, Puchnarewicz M, Johnston A, Wood DM(2012). First Reported Case of Acute Prolonged Neuropsychiatric Toxicity Associated With Analytically Confirmed Recreational Use of Phenazepam. CLINICAL TOXICOLOGY vol. 50, (4) 324-324.
Wood DM, Davies S, Puchnarewicz M, Johnston A, Dargan PI(2012). Methoxetamine: A Ketamine Analogue Associated with Both Ketamine-like Dissociative Effects and Sympathomimetic Toxicity. CLINICAL TOXICOLOGY vol. 50, (4) 342-342.
Kassim S, Hawash A, Johnston A, Croucher R(2012). Validation of self-reported khat chewing amongst khat chewers: an exploratory study. J Ethnopharmacol vol. 140, (1) 193-196.
10.1016/j.jep.2011.12.040
Johnston A(2012). The relevance of factor VIII (FVIII) pharmacokinetics to TDM and hemophilia a treatment: is B domain-deleted FVIII equivalent to full-length FVIII?. Ther Drug Monit vol. 34, (1) 110-117.
10.1097/FTD.0b013e318244fa5a
Baker TM, Goh J, Johnston A, Falvey H, Brede Y, Brown RE(2012). Cost-effectiveness analysis of valsartan versus losartan and the effect of switching. J Med Econ vol. 15, (2) 253-260.
10.3111/13696998.2011.641043
Al Ameri MN, Nayuni N, Anil Kumar KG, Perrett D, Tucker A, Johnston A(2012). The differences between the branded and generic medicines using solid dosage forms: In-vitro dissolution testing. Results Pharma Sci vol. 2, 1-8.
10.1016/j.rinphs.2011.12.001
Al Ameri MN, Epstein M, Johnston A(2011). Generic and therapeutic substitution: a response to our critic. Int J Clin Pharm vol. 33, (6)
10.1007/s11096-011-9564-4
Johnston A, Asmar R, Dahlöf B, Hill K, Jones DA, Jordan J, Livingston M, Macgregor G et al.(2011). Generic and therapeutic substitution: a viewpoint on achieving best practice in Europe. Br J Clin Pharmacol vol. 72, (5) 727-730.
10.1111/j.1365-2125.2011.03987.x
Al Ameri MN, Whittaker C, Tucker A, Yaqoob M, Johnston A(2011). A survey to determine the views of renal transplant patients on generic substitution in the UK. Transpl Int vol. 24, (8) 770-779.
10.1111/j.1432-2277.2011.01268.x
Grossman SE, Johnston A, Vanezis P, Perrett D(2011). Can we assess the age of bruises? An attempt to develop an objective technique. Med Sci Law vol. 51, (3) 170-176.
10.1258/msl.2011.010135
Moore J, He X, Shabir S, HanvesakulPhd R, Benavente D, Cockwell P, Little MA, Ball S et al.(2011). Development and Evaluation of a Composite Risk Score to Predict Kidney Transplant Failure. AM J KIDNEY DIS vol. 57, (5) 744-751.
10.1053/j.ajkd.2010.12.017
Chew AL, Bashir SJ, Johnston A, Barker JNWN, Smith CH(2011). The value of monitoring ciclosporin concentration 2 hours post-dose (C2) in dermatology: A prospective cohort study. J DERMATOL TREAT vol. 22, (2) 79-85.
10.3109/09546630903575539
Moore J, He XA, Liu XA, Shabir S, Ball S, Cockwell P, Inston N, Little MA et al.(2011). Mortality Prediction After Kidney Transplantation: Comparative Clinical Use of 7 Comorbidity Indices. EXP CLIN TRANSPLANT vol. 9, (1) 32-41.
Chik Z, Tucker AT, Shiel JI, Collier DJ, Perrett D, Lee TD, Johnston A(2010). Comparative Pharmacokinetic Assessments of Topical Drugs: Evaluation by Dermatopharmacokinetics, Microdialysis, and Systemic Measurement. J INVEST DERMATOL vol. 130, (12) 2828-2830.
10.1038/jid.2010.212
AlAmeri M, Epstein M, Johnston A(2010). Generic and therapeutic substitutions: are they always ethical in their own terms?. Pharm World Sci vol. 32, (6) 691-695.
10.1007/s11096-010-9429-2
Couchman L, Morgan PE, Spencer EP, Johnston A, Flanagan RJ(2010). Plasma clozapine and norclozapine in patients prescribed different brands of clozapine (Clozaril, Denzapine, and Zaponex). Ther Drug Monit vol. 32, (5) 624-627.
10.1097/FTD.0b013e3181f0a1a2
Johnston A, Stafylas P, Stergiou GS(2010). Effectiveness, safety and cost of drug substitution in hypertension. Br J Clin Pharmacol vol. 70, (3) 320-334.
10.1111/j.1365-2125.2010.03681.x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14951
Wood D, Panayi P, Davies S, Collignon U, Button J, Ramsey J, Johnston A, Holt D et al. (2010). Analysis of recreational drug samples obtained from/left by patients presenting to a busy inner-city Emergency Department. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 70, 289-290.
Johnston A(2010). Challenges of therapeutic substitution of drugs for economic reasons: focus on CVD prevention. Curr Med Res Opin vol. 26, (4) 871-878.
10.1185/03007990903578462
Al Ameri M, Johnston A, Epstein M(2010). Ethical issues in generic and therapeutic substitution. PHARM WORLD SCI vol. 32, (2) 269-269.
Pilling ML, Vanezis P, Perrett D, Johnston A(2010). Visual assessment of the timing of bruising by forensic experts. J Forensic Leg Med vol. 17, (3) 143-149.
10.1016/j.jflm.2009.10.002
Tucker A, Maass A, Bain D, Chen L-H, Azzam M, Dawson H, Johnston A(2010). Augmentation of venous, arterial and microvascular blood supply in the leg by isometric neuromuscular stimulation via the peroneal nerve. Int J Angiol vol. 19, (1) e31-e37.
10.1055/s-0031-1278361
EPSTEIN AM, Al Ameri MN, Johnston A (2009). Ethical issues in generic and therapeutic substitution. Presented at: William Harvey Research Institute, Barts and The London School of Medicine and Dentistry,
Al-Otaibi F, Ghazaly EA, Tucker AT, Johnston A, Perrett D (2009). Development of High Performance Liquid Chromatograph Method for Analysis of Tetracaine for a Tape Stripping Pharmacokinetic Study: A Comparison with Capillary Zone Electrophoresis (CE). THERAPEUTIC DRUG MONITORING. vol. 31, 656-656.
Al-Otaibi F, Tucker AT, Johnston A, Perrett D (2009). Rapid Analysis of Tetracaine for a Tape Stripping Pharmacokinetic Study Using Short-end Capillary Electrophoresis. THERAPEUTIC DRUG MONITORING. vol. 31, 655-655.
Al-Otaibi F, Johnston A, Tucker AT, Lee T, Langford R, Ratcliffe S, Kirby K, Alam C (2009). Systemic Measurement of TDS (R)-Diazepam, Compared with Rectal Diazepam, a Pharmacokinetic Study in Healthy Adult Subjects. THERAPEUTIC DRUG MONITORING. vol. 31, 655-655.
Jones AE, Wilson HK, Meath P, Meng XL, Holt DW, Johnston A, Oellerich M, Armstrong VW et al.(2009). Convenient syntheses of the in vivo carbohydrate metabolites of mycophenolic acid: reactivity of the acyl glucuronide. TETRAHEDRON LETT vol. 50, (35) 4973-4977.
10.1016/j.tetlet.2009.06.060
Al-Otaibi F, Tucker A, Johnston A, Perrett D (2009). Rapid analysis of tetracaine for a tape stripping pharmacokinetic study using short-end capillary electrophoresis. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 68, 299-300.
Jorns TP, Johnston A, Zakrzewska JM(2009). Pilot study to evaluate the efficacy and tolerability of levetiracetam (Keppra((R))) in treatment of patients with trigeminal neuralgia. EUR J NEUROL vol. 16, (6) 740-744.
10.1111/j.1468-1331.2009.02585.x
Payne-James JJ, Anderson WR, Green PG, Johnston A(2009). Provision of forensic medical services to police custody suites in England and Wales: current practice. J Forensic Leg Med vol. 16, (4) 189-195.
10.1016/j.jflm.2008.09.002
Al-Otaibi F, Tucker AT, Johnston A, Perrett D(2009). Rapid analysis of tetracaine for a tape stripping pharmacokinetic study using short-end capillary electrophoresis. Biomed Chromatogr vol. 23, (5) 488-491.
10.1002/bmc.1142
Chik Z, Johnston A, Tucker AT, Kirby K, Alam CA(2009). Correcting endogenous concentrations of testosterone influences bioequivalence and shows the superiority of TDS (R)-testosterone versus Androgel (R). INT J CLIN PHARM TH vol. 47, (4) 262-268.
Wallemacq P, Armstrong VW, Brunet M, Haufroid V, Holt DW, Johnston A, Kuypers D, Le Meur Y et al.(2009). Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference. Ther Drug Monit vol. 31, (2) 139-152.
10.1097/FTD.0b013e318198d092
He X, Moore J, Shabir S, Little MA, Cockwell P, Ball S, Liu X, Johnston A et al.(2009). Comparison of the Predictive Performance of eGFR Formulae for Mortality and Graft Failure in Renal Transplant Recipients. TRANSPLANTATION vol. 87, (3) 384-392.
10.1097/TP.0b013e31819004a1
He X, Moore J, Liu X, Shabir S, Cockwell P, Little MA, Ball S, Inston N et al. (2009). A Simple "Kidney Risk Score" (KRS) and "Mortality Risk Score" (MRS) for Renal Transplant Recipients. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 9, 428-428.
Moore J, Liu X, He X, Shabir S, Ball S, Cockwell P, Inston N, Little MA et al. (2009). Impact of Comorbidity on Mortality Following Renal Transplantation: Comparative Clinical Utility of Seven Scoring Systems. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 9, 593-593.
Moore J, He X, Cockwell P, Little MA, Johnston A, Borrows R(2008). The impact of hemoglobin levels on patient and graft survival in renal transplant recipients. TRANSPLANTATION vol. 86, (4) 564-570.
10.1097/TP.0b013e318181e276
Al-Otaibi F, Johnston A, Tucker A, Lee T, Langford R, Ratcliffe S, Alam C (2008). A randomized, single-dose, two-period, cross-over pharmacokinetic study to compare TDS (R)-diazepam with rectal diazepam in healthy adult subjects. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 65, 1002-1002.
He X, MacPhee I, Johnston A (2008). Cardiovascular risk factors and their management in renal transplant recipients. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 65, 998-999.
Ghazaly E, Joel S, Johnston A (2008). Etoposide catechol, is it an important metabolite?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 65, 984-985.
Mehta V, Johnston A, Cheung R, Bello A, Langford RM(2008). Intravenous parecoxib rapidly leads to COX-2 inhibitory concentration of valdecoxib in the central nervous system. Clin Pharmacol Ther vol. 83, (3) 430-435.
10.1038/sj.clpt.6100304
Cattran DC, Alexopoulos E, Heering P, Hoyer PF, Johnston A, Meyrier A, Ponticelli C, Saito T et al.(2007). Cyclosporin in idiopathic glomerular disease associated with the nephrotic syndrome : Workshop recommendations. KIDNEY INT vol. 72, (12) 1429-1447.
10.1038/sj.ki.5002553
Galanello R, Forni G, Jones A, Kelly A, Willemsen A, He X, Johnston A, Fuller D et al. (2007). A dose escalation study of the pharmacokinetics, safety & efficacy of deferitrin an oral iron chelator in beta thalassaemia patients. BLOOD. vol. 110, 784A-785A.
He X, Holt DW, Johnston A(2007). An algorithm to predict individual MPA AUC for de novo renal transplant patients receiving EC-MPS. TRANSPL INT vol. 20, 115-115.
He X, Holt DW, Johnston A (2007). Predicting MPA AUC for de novo renal transplant patients receiving EC-MPS. THERAPEUTIC DRUG MONITORING. vol. 29, 473-473.
Chik Z, Johnston A, Tucker AT, Burn RT, Perrett D(2007). Validation and application of capillary electrophoresis for the analysis of lidocaine in a skin tape stripping study. BIOMED CHROMATOGR vol. 21, (8) 775-779.
10.1002/bmc.823
Ravic N, Tucker AT, Wareham DW, Johnston A, Hinds CJ (2007). A study of novel oxides of nitrogen generating solution to prevent microbial colonization and ventilator associated pneumonia (VAP). BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 781-781.
Chik Z, Tucker AT, Shiel JI, Collier DJ, Perrett D, Lee TD, Johnston A (2007). Comparative pharmacokinetic assessments of topically applied drugs: evaluation by dermatopharmacokinetic, microdialysis and systemic measurement. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 775-776.
10.1038/jid.2010.212
Collier D, Arunachalam G, Johnston A, Richards S, Shiel J, Wells Z, David C, Caulfield M (2007). Continuing reduction of microalbuminuria and proteinuria during follow-up for the Anglo-Scandinavian Cardiac Outcomes Trial dominance of duration and blood pressure over other effects. JOURNAL OF HYPERTENSION. vol. 25, S150-S150.
Tucker AT, Barnes NC, Johnston A, Elston WJ, Watson D, Wilks M, Rahman R, Rehman I (2007). Formulation and validation of a novel solution of nitric oxide for delivery to the respiratory tract. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 781-781.
El-Safa EA, Fredericks S, MacPhee I, Johnston A, Holt DW (2007). Interindividual variation in response to tacrolimus assessed by IL-2 gene expression in renal transplant patients. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 789-790.
Jorns TP, Johnston A, Zakrzewska JM (2007). Pilot study to evaluate the efficacy and tolerability of levetiracetam in the treatment of patients with trigeminal neuralgia. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 785-786.
Ghazaly EA, Johnston A, Joel SP (2007). Simultaneous determination of 6 beta-hydroxycortisol and cortisol in human urine by high performance liquid chromatography using ultraviolet detector for CYP3A4 phenotyping. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 790-790.
Fredericks S, Jorga A, MacPhee IAM, Reboux S, Shiferaw E, Moreton M, Carter ND, Holt DW et al.(2007). Multi-drug resistance gene-1 (MDR-1) haplotypes and the CYP3A5*1 genotype have no influence on ciclosporin dose requirements as assessed by C0 or C2 measurements. CLIN TRANSPLANT vol. 21, (2) 252-257.
10.1111/j.1399-0012.2006.00635.x
Brown KM, Kondeatis E, Vaughan RW, Kon SP, Farmer CKT, Taylor JD, He X, Johnston A et al. (2007). Influence of donor C3 allotype on late renal transplantation outcome. MOLECULAR IMMUNOLOGY. vol. 44, 157-158.
10.1016/j.molimm.2006.07.029
Johnston A, He X, Holt DW(2006). Bioequivalence of enteric-coated mycophenolate sodium and mycophenolate mofetil: a meta-analysis of three studies in stable renal transplant recipients. Transplantation vol. 82, (11) 1413-1418.
10.1097/01.tp.0000242137.68863.89
El-Safa EA, Fredericks S, MacPhee I, Holt DW, Johnston A (2006). Paradoxical response to tacrolimus assessed by interleukin-2 gene expression. Transplant Proc. vol. 38, 3327-3330.
10.1016/j.transproceed.2006.10.181
Griffiths CEM, Katsambas A, Dijkmans BAC, Finlay AY, Ho VC, Johnston A, Luger TA, Mrowietz U et al. (2006). Update on the use of ciclosporin in immune-mediated dermatoses. BRITISH JOURNAL OF DERMATOLOGY. vol. 155, 1-16.
10.1111/j.1365-2133.2006.07343.x
Brown KM, Kondeatis E, Vaughan RW, Kon SP, Farmer CKT, Taylor JD, He X, Johnston A et al.(2006). Influence of donor C3 allotype on late renal-transplantation outcome. NEW ENGL J MED vol. 354, (19) 2014-2023.
10.1056/NEJMoa052825
Chik Z, Lee TD, Holt DW, Johnston A, Tucker AT(2006). Validation of high-performance liquid chromatographic-mass spectrometric method for the analysis of lidocaine in human plasma. J Chromatogr Sci vol. 44, (5) 262-265.
10.1093/chromsci/44.5.262
Dooldeniya MD, Dupont PJ, He X, Johnson RJ, Joshi T, Basra R, Johnston A, Warrens AN(2006). Renal transplantation in indo-asian patients in the UK. AM J TRANSPLANT vol. 6, (4) 761-769.
10.1111/j.1600-6143.2006.01262.x
Chik Z, Johnston A, Tucker AT, Chew SL, Michaels L, Alam CAS(2006). Pharmacokinetics of a new testosterone transdermal delivery system, TDS-testosterone in healthy males. Br J Clin Pharmacol vol. 61, (3) 275-279.
10.1111/j.1365-2125.2005.02542.x
Tucker AT, Chik Z, Michaels L, Kirby K, Seed MP, Johnston A, Alam CAS(2006). Study of a combined percutaneous local anaesthetic and the TDS system for venepuncture. Anaesthesia vol. 61, (2) 123-126.
10.1111/j.1365-2044.2005.04432.x
Kenyon SL, Ramsey JD, Lee T, Johnston A, Holt DW(2005). Analysis for identification in amnesty bin samples from dance venues. THER DRUG MONIT vol. 27, (6) 793-798.
10.1097/01.ftd.0000180227.04137.3c
Moreton M, Fredericks S, McKeown DA, Shiferaw EW, MacPhee LAM, Johnston A, Holt DW(2005). CYP3A5 genotype does not influence the blood concentration of tacrolimus measured with the Abbott immunoassay. CLIN CHEM vol. 51, (11) 2214-2215.
10.1373/clinchem.2005.056895
Rocks SA, Davies CA, Hicks SL, Webb AJ, Klocke R, Timmins GS, Johnston A, Jawad ASM et al.(2005). Measurement of S-nitrosothiols in extracellular fluids from healthy human volunteers and rheumatoid arthritis patients, using electron paramagnetic resonance spectrometry. Free Radic Biol Med vol. 39, (7) 937-948.
10.1016/j.freeradbiomed.2005.05.007
Turner M, McCrory P, Johnston A(2005). Time for tea, anyone?. BRIT J SPORT MED vol. 39, (10) Article e37,
10.1136/bjsm.2004.017038
Fredericks S, Moreton M, MacPhee IAM, Mohamed M, Marlowe S, Jorga AM, Johnston A, Carter ND et al.(2005). Genotyping cytochrome P450 3A5 using the light cycler. ANN CLIN BIOCHEM vol. 42, 376-381.
10.1258/0004563054889927
Chew AL, Johnston A, Barker JNWN, Smith CH (2005). The value of ciclosporin C2 monitoring in dermatology: a pilot study. BRITISH JOURNAL OF DERMATOLOGY. vol. 153, 39-39.
Nashan B, Bock A, Bosmans JL, Budde K, de Fijter H, Jaques B, Johnston A, Luck R et al.(2005). Use of neoral C-2 monitoring: a European consensus. TRANSPL INT vol. 18, (7) 768-778.
10.1111/j.1432-2277.2005.00151.x
Perrie JA, Harding JR, Holt DW, Johnston A, Meath P, Stachulski AV(2005). Effective synthesis of 1,beta-acyl glucuronides by selective acylation. ORG LETT vol. 7, (13) 2591-2594.
10.1021/ol0507165
Chik Z, Johnston A, Tucker AT, Chew SL, Alam CAS(2005). Pharmacokinetic study of the transdermal delivery system, TDS (c)-testosterone in healthy subjects. BRIT J CLIN PHARMACO vol. 59, (5) 636-636.
He X, Johnston A(2005). Risk factors for allograft failure in United kingdom renal transplant recipients treated with cyclosporine A. Transplantation vol. 79, (8) 953-957.
10.1097/01.tp.0000156159.72708.de
Jorga A, Johnston A(2005). Novel therapies in transplantation. Expert Opin Investig Drugs vol. 14, (3) 295-304.
10.1517/13543784.14.3.295
MacPhee IAM, Fredericks S, Mohamed M, Moreton M, Carter ND, Johnston A, Goldberg L, Holt DW(2005). Tacrolimus pharmacogenetics: The CYP3A5*1 allele predicts low dose-normalized tacrolimus blood concentrations in whites and south Asians. TRANSPLANTATION vol. 79, (4) 499-502.
10.1097/01.TP.0000151766.73249.12
Buchler M, Johnston A (2005). Seeking optimal prescription of cyclosporine ME. THERAPEUTIC DRUG MONITORING. vol. 27, 3-6.
10.1097/00007691-200502000-00002
Holt DW, Moreton M, Laamanen K, Johnston A (2005). A microparticle enzyme immunoassay to measure sirolimus. TRANSPLANTATION PROCEEDINGS. vol. 37, 182-184.
10.1016/j.transproceed.2004.12.207
Wolff CB, Checkley SK, Bhageerutty G, Bhatt H, Johnston A, Collier DJ, Tachtsidis I, Garvie N et al. (2005). Circulation time in man from lung to periphery as an indirect index of cardiac output. Adv Exp Med Biol. vol. 566, 311-316.
10.1007/0-387-26206-7_41
Rocks S, Davies C, Hicks S, Webb A, Klocke R, Timmins G, Johnston A, Jawad A et al. (2005). Validation and clinical applications of a new EPR assay for plasma S-nitrosothiols. FREE RADICAL BIOLOGY AND MEDICINE. vol. 39, S56-S56.
Jorga A, Holt DW, Yaqoob M, Whittaker C, Johnston A(2004). A survey to determine the blood concentration of cyclosporine 2 hours postdose in stable renal transplant patients. Transplant Proc vol. 36, (10) 3239-3241.
10.1016/j.transproceed.2004.10.077
He X, Johnston A(2004). Early acute rejection does not affect chronic allograft nephropathy and death censored graft failure. Transplant Proc vol. 36, (10) 2993-2996.
10.1016/j.transproceed.2004.10.070
Holt DW, McKeown DA, Lee TD, Hicks D, Cal P, Johnston A(2004). The relative proportions of sirolimus metabolites in blood using HPLC with mass-spectrometric detection. Transplant Proc vol. 36, (10) 3223-3225.
10.1016/j.transproceed.2004.12.005
Ravic M, Warrington S, Boyce M, Dunn K, Johnston A(2004). Repeated dosing with donepezil does not affect the safety, tolerability or pharmacokinetics of single-dose thioridazine in young volunteers. Br J Clin Pharmacol vol. 58 Suppl 1, 34-40.
10.1111/j.1365-2125.2004.01800.x
Zacharowski P, Zacharowski K, Donnellan C, Johnston A, Vojnovic I, Forte P, Del Soldato P, Benjamin N et al.(2004). The effects and metabolic fate of nitroflurbiprofen in healthy volunteers. Clin Pharmacol Ther vol. 76, (4) 350-358.
10.1016/j.clpt.2004.05.008
Johnston A, Belitsky P, Frei U, Horvath J, Hoyer P, Helderman JH, Oellerich M, Pollard S et al.(2004). Potential clinical implications of substitution of generic cyclosporine formulations for cyclosporine microemulsion (Neoral) in transplant recipients. Eur J Clin Pharmacol vol. 60, (6) 389-395.
10.1007/s00228-004-0774-8
Holt DW, Johnston A(2004). Monitoring immunosuppressive drugs - Has it a future?. THER DRUG MONIT vol. 26, (3) 244-247.
10.1097/00007691-200406000-00003
MacPhee IAM, Fredericks S, Tai T, Syrris P, Carter ND, Johnston A, Goldberg L, Holt DW(2004). The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation. AM J TRANSPLANT vol. 4, (6) 914-919.
10.1111/j.1600-6143.2004.00435.x
He X, Johnston A(2004). Variable cyclosporine exposure: a risk factor for chronic allograft nephropathy and graft loss?. Transplant Proc vol. 36, (5) 1321-1326.
10.1016/j.transproceed.2004.04.084
Griffiths CEM, Dubertret L, Ellis CN, Finlay AY, Finzi AF, Ho VC, Johnston A, Katsambas A et al.(2004). Ciclosporin in psoriasis clinical practice: an international consensus statement. BRIT J DERMATOL vol. 150, 11-23.
10.1111/j.0366-077X.2004.05949.x
Jorga A, Holt DW, Johnston A(2004). Therapeutic drug monitoring of cyclosporine. Transplant Proc vol. 36, (2 Suppl) 396S-403S.
10.1016/j.transproceed.2004.01.013
Jorga A, Johnston A, Holt DW(2004). Patient management by cyclosporine C2 monitoring. TRANSPLANTATION vol. 77, (2) 323-324.
10.1097/01.TP.0000101038.20305.C9
Holt DW, Johnston A(2004). Chapter 11 monitoring immunosuppressive drugs. vol. 5, 273-296.
10.1016/S1567-7192(04)80012-3
Wilson S, Johnston A, Robson J, Murchie P, Mann DM, Natarajan S(2004). Cholesterol screening in people aged > 50 years effectively identifies people at high risk of coronary disease. Evidence-Based Healthcare vol. 8, (1) 15-17.
10.1016/j.ehbc.2003.12.018
Johnston AJ, Steiner LA, O'Connell M, Chatfield DA, Gupta AK, Menon DK(2004). Pharmacokinetics and pharmacodynamics of dopamine and norepinephrine in critically ill head-injured patients. Intensive Care Med vol. 30, (1) 45-50.
10.1007/s00134-003-2032-4
He X, Johnston A (2004). Pre-transplant risk factors for UK renal transplant patient with ciclosporin. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 4, 489-489.
Johnston AJ, Steiner LA, Chatfield DA, Coleman MR, Coles JP, Al-Rawi PG, Menon DK, Gupta AK(2003). Effects of propofol on cerebral oxygenation and metabolism after head injury. Br J Anaesth vol. 91, (6) 781-786.
10.1093/bja/aeg256
Johnston A(2003). The pharmacokinetics of voriconazole. Br J Clin Pharmacol vol. 56 Suppl 1,
10.1046/j.1365-2125.2003.01991.x
Clarke A, Johnson ES, Mallard N, Corn TH, Johnston A, Boyce M, Warrington S, MacMahon DG(2003). A new low-dose formulation of selegiline: clinical efficacy, patient preference and selectivity for MAO-B inhibition. J NEURAL TRANSM vol. 110, (11) 1257-1271.
10.1007/s00702-003-0042-6
Steiner LA, Coles JP, Johnston AJ, Czosnyka M, Fryer TD, Smielewski P, Chatfield DA, Salvador R et al.(2003). Responses of posttraumatic pericontusional cerebral blood flow and blood volume to an increase in cerebral perfusion pressure. J Cereb Blood Flow Metab vol. 23, (11) 1371-1377.
10.1097/01.WCB.0000090861.67713.10
Steiner LA, Coles JP, Johnston AJ, Chatfield DA, Smielewski P, Fryer TD, Aigbirhio FI, Clark JC et al.(2003). Assessment of cerebrovascular autoregulation in head-injured patients: a validation study. Stroke vol. 34, (10) 2404-2409.
10.1161/01.STR.0000089014.59668.04
Charmandari E, Pincus SM, Matthews DR, Johnston A, Brook CGD, Hindmarsh PC(2003). Sexual dimorphism in the synchrony of joint growth hormone and cortisol dynamics in children with classic 21-hydroxylase deficiency. J PEDIATR ENDOCR MET vol. 16, (8) 1119-1130.
10.1515/jpem.2003.16.8.1119
Wilson S, Johnston A, Robson J(2003). Methods to identify increased risk of coronary disease in the general population - Conclusion is oversimplification - Authors' reply. BRIT MED J vol. 327, (7415) 619-619.
He S, Johnston A (2003). Fluctuating ciclosporin exposure - A risk factor for graft loss?. THERAPEUTIC DRUG MONITORING. vol. 25, 511-511.
Trompeter R, Fitzpatrick M, Hutchinson C, Johnston A(2003). Longitudinal evaluation of the pharmacokinetics of cyclosporin microemulsion (Neoral((R))) in pediatric renal transplant recipients and assessment of C-2 level as a marker for absorption. PEDIATR TRANSPLANT vol. 7, (4) 282-288.
10.1034/j.1399-3046.2003.00077.x
Steiner LA, Johnston AJ, Chatfield DA, Czosnyka M, Coleman MR, Coles JP, Gupta AK, Pickard JD et al.(2003). The effects of large-dose propofol on cerebrovascular pressure autoregulation in head-injured patients. Anesth Analg vol. 97, (2) 572-576.
10.1213/01.ane.0000070234.17226.b0
Wilson S, Johnston A, Robson J, Poulter N, Collier D, Feder G, Caulfield MJ(2003). Comparison of methods to identify individuals at increased risk of coronary disease from the general population. BMJ vol. 326, (7404)
10.1136/bmj.326.7404.1436
Pollard S, Nashan B, Johnston A, Hoyer P, Belitsky P, Keown P, Helderman H(2003). A pharmacokinetic and clinical review of the potential clinical impact of using different formulations of cyclosporin A. CLIN THER vol. 25, (6) 1654-1669.
10.1016/S0149-2918(03)80161-3
Johnston A, Ramsey J(2003). Re: Drugs, driving and sobriety tests. J Clin Forensic Med vol. 10, (2) 126-127.
10.1016/S1353-1131(03)00033-6
Holt DW, Denny K, Lee TD, Johnston A(2003). Therapeutic monitoring of sirolimus: Its contribution to optimal prescription. TRANSPLANT P vol. 35, (3A) 157S-161S.
10.1016/S0041-1345(03)00214-8
Jorga A, Collier D, Priston B, Clavel D, Johnston A (2003). Adults' reactions to inhaled denatonium benzoate (Bitrex (R)). BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 55, 447-447.
Wilson S, Johnston A, Collier DJ, Caulfield M (2003). Feasibility of enrolling patients to hypertension outcome trials based on an assessment of their cardiovascular risk. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 55, 425-426.
Johnston A, Chusney G, Schütz E, Oellerich M, Lee TD, Holt DW(2003). Monitoring cyclosporin in blood: between-assay differences at trough and 2 hours post-dose (C2). Ther Drug Monit vol. 25, (2) 167-173.
10.1097/00007691-200304000-00005
Wilson S, Johnston A, Robson J, Poulter NR, Collier DJ, Feder GS, Caulfield MJ(2003). Predicting coronary risk in the general population--is it necessary to measure high-density lipoprotein cholesterol?. J Cardiovasc Risk vol. 10, (2) 137-141.
10.1097/01.hjr.0000060844.48106.ff
Johnston A, Holt D, Lee T, Clark E, Dunn K, Boyce M (2003). Urinary 6 beta-hydroxycortisol: cortisol ratio as an in vivo marker of CYP3A4 activity - spot vs 24 h collections. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 55, 440-440.
He S, Johnston A (2003). Variable ciclosporin exposure: a risk factor for chronic rejection and graft loss?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 55, 434-434.
Johnston A, Levy GA(2003). The TMC study. LANCET vol. 361, (9354) 346-347.
10.1016/S0140-6736(03)12347-1
Macphee IAM, Fredericks S, Tai T, Syrris P, Carter ND, Johnston A, Goldberg L, Holt DW(2002). Tacrolimus pharmacogenetics: Polymorphisms associated with expression of cytochrome P4503A5 and P-glycoprotein correlate with dose requirement. TRANSPLANTATION vol. 74, (11) 1486-1489.
10.1097/01.TP.0000045761.71385.9F
Banner NR, David OJ, Leaver N, Davis J, Breen J, Johnston A, Yacoub MH(2002). Pharmacokinetics of oral cyclosporine (Neoral) in heart transplant recipients during the immediate period after surgery. TRANSPLANT INT vol. 15, (12) 649-654.
10.1007/s00147-002-0491-0
Wolff CB, Checkley SK, Bhageerutty G, Bhatt H, Johnston A, Collier DJ, Garvie N, Rosenberg ME et al. (2002). Circulation time in man from lung to periphery - pulse and non-pulse oximetry. JOURNAL OF PHYSIOLOGY-LONDON. vol. 543, 41P-41P.
Wilson S, Johnston A, Robson J, Poulter N, Collier D, Feder G, Caulfield M (2002). Should we measure high density lipoprotein cholesterol in people with hypertension?. JOURNAL OF HYPERTENSION. vol. 20, S150-S150.
Cole E, Midtvedt K, Johnston A, Pattison J, O'Grady C(2002). Recommendations for the implementation of Neoral C-2 monitoring in clinical practice. TRANSPLANTATION vol. 73, (9) S19-S22.
10.1097/00007890-200205151-00004
Charmandari E, Pincus SM, Matthews DR, Johnston A, Brook CGD, Hindmarsh PC(2002). Oral hydrocortisone administration in children with classic 21-hydroxylase deficiency leads to more synchronous joint GH and cortisol secretion. J CLIN ENDOCR METAB vol. 87, (5) 2238-2244.
10.1210/jcem.87.5.8503
Charmandari E, Johnston A, Honour JW, Brook CGD, Hindmarsh PC(2002). Treatment with flutamide decreases cortisol clearance: Implications for therapy in congenital adrenal hyperplasia. J PEDIATR ENDOCR MET vol. 15, (4) 435-439.
10.1515/jpem.2002.15.4.435
Levy G, Burra P, Cavallari A, Duvoux C, Lake J, Mayer AD, Mies S, Pollard SG et al.(2002). Improved clinical outcomes for liver transplant recipients using cyclosporine monitoring based on 2-hr post-dose levels (C-2). TRANSPLANTATION vol. 73, (6) 953-959.
10.1097/00007890-200203270-00022
Trull A, Hughes V, Cooper D, Wilkins M, Gimson A, Friend P, Johnston A, Sharples L et al.(2002). Influence of albumin supplementation on tacrolimus and cyclosporine therapy early after liver transplantation. LIVER TRANSPLANT vol. 8, (3) 224-232.
10.1053/jlts.2002.31347
Kahan BD, Keown P, Levy GA, Johnston A(2002). Therapeutic drug monitoring of inununosuppressant drugs in clinical practice. CLIN THER vol. 24, (3) 330-350.
10.1016/S0149-2918(02)85038-X
Ramsey JD, Holt DW, Johnston A(2002). New method to monitor drugs at dance venues - Perhaps results of testing tablets should be made public - Reply. BRIT MED J vol. 324, (7332) 299-300.
Price CP (2002). Biomarkers in renal disease. BIOMARKERS OF DISEASE: AN EVIDENCE-BASED APPROACH. Editors: Trull, A, Demers, LM, Holt, DW, Johnston, A et al., 45-55.
10.1017/CBO9780511545962.006
Timms PM, Campbell S, Srikanthan V, Price CP (2002). Matrix metalloproteinases and their tissue inhibitors. BIOMARKERS OF DISEASE: AN EVIDENCE-BASED APPROACH. Editors: Trull, A, Demers, LM, Holt, DW, Johnston, A et al., 379-388.
10.1017/CBO9780511545962.038
Johnston AJ, Ascher J, Leadbetter R, Schmith VD, Patel DK, Durcan M, Bentley B(2002). Pharmacokinetic optimisation of sustained-release bupropion for smoking cessation. Drugs vol. 62 Suppl 2, 11-24.
10.2165/00003495-200262002-00002
Johnston A (2002). The use of biomarkers for monitoring the response to immunosuppressive drug therapy. BIOMARKERS OF DISEASE: AN EVIDENCE-BASED APPROACH. Editors: Trull, A, Demers, LM, Holt, DW, Johnston, A et al., 451-460.
10.1017/CBO9780511545962.046
Charmandari E, Matthews DR, Johnston A, Brook CGD, Hindmarsh PC(2001). Serum cortisol and 17-hydroxyprogesgterone interrelation in classic 21-hydroxylase deficiency: Is current replacement therapy satisfactory?. J CLIN ENDOCR METAB vol. 86, (10) 4679-4685.
10.1210/jcem.86.10.7972
Ramsey JD, Butcher MA, Murphy MF, Lee T, Johnston A, Holt DW(2001). A new method to monitor drugs at dance venues. BRIT MED J vol. 323, (7313) 603-603.
10.1136/bmj.323.7313.603
Holt DW, Denny K, Lee T, Johnston A (2001). Cyclosporin Measurement - who cares about inaccuracy.?. ACCREDITATION AND QUALITY ASSURANCE. vol. 6, 405-408.
10.1007/PL00010465
Wilson S, Collier D, Johnston A, Poulter N, Feder G, Robson J, Caulfield M, Anglo-Scandinavian Cardiac Outcomes Trial(2001). Evaluation of cardiovascular risk equations using the ASCOT cohort. J Hum Hypertens vol. 15 Suppl 1, S31-S33.
10.1038/sj.jhh.1001084
Charmandari E, Lichtarowicz-Krynska EJ, Hindmarsh PC, Johnston A, Aynsley-Green A, Brook CGD(2001). Congenital adrenal hyperplasia: management during critical illness. ARCH DIS CHILD vol. 85, (1) 26-28.
10.1136/adc.85.1.26
Shaw G, Johnston A, Holt DW(2001). NHS laboratories can provide a service to the pharmaceutical industry: a personal experience. Ann Clin Biochem vol. 38, (Pt 4) 411-412.
Charmandari E, Hindmarsh PC, Johnston A, Brook CGD(2001). Congenital adrenal hyperplasia due to 21-hydroxylase deficiency: Alterations in cortisol pharmacokinetics at puberty. J CLIN ENDOCR METAB vol. 86, (6) 2701-2708.
10.1210/jcem.86.6.7522
Gopaul NK, Manraj MD, Hébé A, Lee Kwai Yan S, Johnston A, Carrier MJ, Anggård EE(2001). Oxidative stress could precede endothelial dysfunction and insulin resistance in Indian Mauritians with impaired glucose metabolism. Diabetologia vol. 44, (6) 706-712.
10.1007/s001250051679
Hardwick JB, Tucker AT, Wilks M, Johnston A, Benjamin N(2001). A novel method for the delivery of nitric oxide therapy to the skin of human subjects using a semi-permeable membrane. Clin Sci (Lond) vol. 100, (4) 395-400.
10.1042/CS20000187
Charmandari E, Johnston A, Brook CG, Hindmarsh PC(2001). Bioavailability of oral hydrocortisone in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J Endocrinol vol. 169, (1) 65-70.
10.1677/joe.0.1690065
David OJ, Johnston A(2001). Limited sampling strategies for estimating cyclosporin area under the concentration-time curve: review of current algorithms. Ther Drug Monit vol. 23, (2) 100-114.
10.1097/00007691-200104000-00003
Charmandari E, Meadows N, Patel M, Johnston A, Benjamin N(2001). Plasma nitrate concentrations in children with infectious and noninfectious diarrhea. J Pediatr Gastroenterol Nutr vol. 32, (4) 423-427.
10.1097/00005176-200104000-00006
Farrand P, Rowe RM, Johnston A, Murdoch H(2001). Prevalence, age of onset and demographic relationships of different areca nut habits amongst children in Tower Hamlets, London. Br Dent J vol. 190, (3) 150-154.
10.1038/sj.bdj.4800909
Cooney GF, Johnston A(2001). Neoral C-2 monitoring in cardiac transplant patients. Transplant Proc vol. 33, (1-2) 1572-1575.
10.1016/s0041-1345(00)02598-7
Cooney GF, Johnston A (2001). Noeral C-2 monitoring in cardiac transplant patients. TRANSPLANTATION PROCEEDINGS. vol. 33, 1572-1575.
10.1016/S0041-1345(00)02598-7
Johnston A, Holt DW(2001). Immunosuppressant drugs--the role of therapeutic drug monitoring. Br J Clin Pharmacol vol. 52 Suppl 1, 61S-73S.
10.1046/j.1365-2125.2001.0520s1061.x
Holt DW, Johnston A (2000). The impact of cyclosporin formulation on clinical outcomes. TRANSPLANTATION PROCEEDINGS. vol. 32, 1552-1555.
10.1016/s0041-1345(00)01339-7
Belitsky P, Dunn S, Johnston A, Levy G(2000). Impact of absorption profiling on efficacy and safety of cyclosporin therapy in transplant recipients. Clin Pharmacokinet vol. 39, (2) 117-125.
10.2165/00003088-200039020-00003
Johnston A, Marsden JT, Holt DW(1988). The influence of haematocrit on blood cyclosporin measurements in vivo. Br J Clin Pharmacol vol. 25, (4) 509-513.
10.1111/j.1365-2125.1988.tb03336.x
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