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Publications:  Prof Charles Hinds

Tridente A, Holloway PAH, Hutton P, Gordon AC, Mills GH, Clarke GM, Chiche JD, Stuber F et al.(2019). Methodological challenges in European ethics approvals for a genetic epidemiology study in critically ill patients: The GenOSept experience. BMC Medical Ethics vol. 20, (1)
10.1186/s12910-019-0370-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59107
Antcliffe DB, Burnham KL, Al-Beidh F, Santhakumaran S, Brett SJ, Hinds CJ, Ashby D, Knight JC et al.(2019). Transcriptomic signatures in sepsis and a differential response to steroids from the VaNISH randomized trial. American Journal of Respiratory and Critical Care Medicine vol. 199, (8) 980-986.
10.1164/rccm.201807-1419OC
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58624
Sweeney TE, Perumal TM, Henao R, Nichols M, Howrylak JA, Choi AM, Bermejo-Martin JF, Almansa R et al.(2018). A community approach to mortality prediction in sepsis via gene expression analysis. Nature Communications vol. 9, (1)
10.1038/s41467-018-03078-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58622
Annane D, Mira JP, Ware LB, Gordon AC, Hinds CJ, Christiani DC, Sevransky J, Barnes K et al.(2018). Pharmacogenomic biomarkers do not predict response to drotrecogin alfa in patients with severe sepsis. Annals of Intensive Care vol. 8, (1)
10.1186/s13613-018-0353-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58138
TORRANCE H, LONGBOTTOM R, VIVIAN M, Lalabekyan B, ABBOTT TEF, ACKLAND GL, HINDS CJ, PEARSE RM et al.(2018). Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery. PLoS ONE vol. 13, (9)
10.1371/journal.pone.0203795
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45023
Lashin HMS, Nadkarni S, Oggero S, Jones HR, Knight JC, Hinds CJ, Perretti M(2018). Microvesicle Subsets in Sepsis Due to Community Acquired Pneumonia Compared to Faecal Peritonitis. Shock vol. 49, (4) 393-401.
10.1097/SHK.0000000000000989
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44531
Tridente A, Bion J, Mills GH, Gordon AC, Clarke GM, Walden A, Hutton P, Holloway PAH et al.(2017). Derivation and validation of a prognostic model for postoperative risk stratification of critically ill patients with faecal peritonitis. Annals of Intensive Care vol. 7, (1)
10.1186/s13613-017-0314-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58629
Scicluna BP, van Vught LA, Zwinderman AH, Wiewel MA, Davenport EE, Burnham KL, Nürnberg P, Schultz MJ et al.(2017). Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study. Lancet Respir Med vol. 5, (10) 816-826.
10.1016/S2213-2600(17)30294-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58625
Burnham KL, Davenport EE, Radhakrishnan J, Humburg P, Gordon AC, Hutton P, Svoren-Jabalera E, Garrard C et al.(2017). Shared and distinct aspects of the sepsis transcriptomic response to fecal peritonitis and pneumonia. American Journal of Respiratory and Critical Care Medicine vol. 196, (3) 328-339.
10.1164/rccm.201608-1685OC
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58630
Scherag A, Schöneweck F, Kesselmeier M, Taudien S, Platzer M, Felder M, Sponholz C, Rautanen A et al.(2016). Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28 Day Mortality. EBioMedicine vol. 12, 239-246.
10.1016/j.ebiom.2016.08.043
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58621
Longbottom ER, Torrance HDT, Owen HC, Fragkou PC, Hinds CJ, Pearse RM, O'Dwyer MJ(2016). Features of Postoperative Immune Suppression Are Reversible with Interferon Gamma and Independent of Interleukin-6 Pathways. Annals of Surgery vol. 264, (2) 370-377.
10.1097/SLA.0000000000001484
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11890
Davenport EE, Burnham KL, Radhakrishnan J, Humburg P, Hutton P, Mills TC, Rautanen A, Gordon AC et al.(2016). Genomic landscape of the individual host response and outcomes in sepsis: A prospective cohort study. The Lancet Respiratory Medicine vol. 4, (4) 259-271.
10.1016/S2213-2600(16)00046-1
Raja M, Torrance H, Longbottom ER, Stroud AJ, Vivian ME, Zolfaghari PS, Pearse RM, Hinds CJ et al.(2015). Long-Term Follow-Up of Sepsis Induced Immunoparalysis. Intensive Care Med Exp vol. 3, (Suppl 1)
10.1186/2197-425X-3-S1-A49
Longbottom ER, Torrance H, Owen HC, Hinds CJ, Pearse RM, O'Dwyer MJ(2015). Post-operative immune suppression is reversible with interferon gamma and independent of IL-6 pathways. Intensive Care Med Exp vol. 3, (Suppl 1)
10.1186/2197-425X-3-S1-A820
Torrance H, Brohi K, Warnes G, Owen HC, Hinds CJ, Pennington DJ, O'Dwyer MJ(2015). T-helper cell polarisation following severe polytrauma. Intensive Care Med Exp vol. 3, (Suppl 1)
10.1186/2197-425X-3-S1-A848
Owen HC, Torrance H, Barnes MR, Brohi K, Knight JC, Hinds CJ, O'Dwyer MJ(2015). The Role of Micrornas in The Development of Hospital Acquired Infection in Polytrauma Patients. Intensive Care Med Exp vol. 3, (Suppl 1)
10.1186/2197-425X-3-S1-A35
Jones TF, Owen HC, Torrance HDT, Pirmadjid N, Brohi K, Hinds CJ, O'Dwyer MJ (2015). MicroRNA-mediated regulation of IL-10, IL-12 and TNFα gene expression in severely injured trauma patients. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. vol. 23,
10.1186/1757-7241-23-S2-O5
Tridente A, Clarke GM, Walden A, Gordon AC, Hutton P, Chiche JD, Holloway PAH, Mills GH et al.(2015). Association between trends in clinical variables and outcome in intensive care patients with faecal peritonitis: Analysis of the GenOSept cohort. Critical Care vol. 19, (1)
10.1186/s13054-015-0931-8
Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ(2015). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Annals of Surgery vol. 261, (4) 751-759.
10.1097/SLA.0000000000000653
Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O¿Dwyer MJ(2015). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Ann Surg vol. 261, (4) 751-759.
10.1097/SLA.0000000000000653
MacDonald N, Ahmad T, Mohr O, Kirk-Bayley J, Moppett I, Hinds CJ, Pearse RM(2015). Dynamic preload markers to predict fluid responsiveness during and after major gastrointestinal surgery: An observational substudy of the OPTIMISE trial. British Journal of Anaesthesia vol. 114, (4) 598-604.
10.1093/bja/aeu398
Torrance HD, Vivian ME, Brohi K, Prowle JR, Pearse RM, Owen HC, Hinds CJ, O'Dwyer MJ(2015). Changes in gene expression following trauma are related to the age of transfused packed red blood cells. J Trauma Acute Care Surg vol. 78, (3) 535-542.
10.1097/TA.0000000000000534
Owen HC, Torrance HDT, Jones TF, Pearse RM, Hinds CJ, Brohi K, O'Dwyer MJ(2015). Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma. Journal of Trauma and Acute Care Surgery vol. 79, (5) 766-772.
10.1097/TA.0000000000000850
https://qmro.qmul.ac.uk/xmlui/handle/123456789/8032
Rautanen A, Mills TC, Gordon AC, Hutton P, Steffens M, Nuamah R, Chiche JD, Parks T et al.(2015). Genome-wide association study of survival from sepsis due to pneumonia: An observational cohort study. The Lancet Respiratory Medicine vol. 3, (1) 53-60.
10.1016/S2213-2600(14)70290-5
Mills TC, Chapman S, Hutton P, Gordon AC, Bion J, Chiche JD, Holloway PAH, Stüber F et al.(2015). Variants in the mannose-binding lectin gene MBL2 do not associatewith sepsis susceptibility or survival in a large european cohort. Clinical Infectious Diseases vol. 61, (5) 695-703.
10.1093/cid/civ378
Torrance HDT, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ (2014). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. vol. 22,
10.1186/1757-7241-22-S1-O7
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12107
Pearse RM, Harrison DA, MacDonald N, Gillies MA, Blunt M, Ackland G, Grocott MPW, Ahern A et al.(2014). Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review. JAMA vol. 311, (21) 2181-2190.
10.1001/jama.2014.5305
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11483
Mills TC, Rautanen A, Elliott KS, Parks T, Naranbhai V, Ieven MM, Butler CC, Little P et al.(2014). IFITM3 and Susceptibility to Respiratory Viral Infections in the Community. JOURNAL OF INFECTIOUS DISEASES vol. 209, (7) 1028-1031.
10.1093/infdis/jit468
Tridente A, Clarke GM, Walden A, McKechnie S, Hutton P, Mills GH, Gordon AC, Holloway PAH et al.(2014). Patients with faecal peritonitis admitted to European intensive care units: an epidemiological survey of the GenOSept cohort. INTENSIVE CARE MEDICINE vol. 40, (2) 202-210.
10.1007/s00134-013-3158-7
Owen HC, Torrance HD, Brohi K, Hinds CJ, O Dwyer MJ(2014). 1068. MicroRNA-regulated immunosuppression in severely injured polytrauma patients. Intensive Care Medicine Experimental vol. 2,
10.1186/2197-425X-2-S1-P84
Dalli J, Norling LV, Montero-Melendez T, Federici Canova D, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ et al.(2014). Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis. EMBO Mol Med vol. 6, (1) 27-42.
10.1002/emmm.201303503
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10756
Walden AP, Clarke GM, McKechnie S, Hutton P, Gordon AC, Rello J, Chiche J-D, Stueber F et al.(2014). Patients with community acquired pneumonia admitted to European intensive care units: an epidemiological survey of the GenOSept cohort. CRITICAL CARE vol. 18, (2) Article ARTN R58,
10.1186/cc13812
Fragkou PC, Torrance HD, Pearse RM, Ackland GL, Prowle JR, Owen HC, Hinds CJ, O'Dwyer MJ(2014). Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study. Crit Care vol. 18, (5) 014-0541.
10.1186/s13054-014-0541-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12111
Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M(2013). Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Mol Cell Proteomics vol. 12, (8) 2205-2219.
10.1074/mcp.M113.028589
Perretti M, Dalli J, Norling LV, Montero-Melendez T, Hinds C (2013). Neutrophil Microparticles are heterogenous in content and function. FASEB JOURNAL. vol. 27,
10.1096/fasebj.27.1_supplement.138.5
Bangash MN, Patel NSA, Benetti E, Collino M, Hinds CJ, Thiemermann C, Pearse RM(2013). Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. Crit Care vol. 17, (2)
10.1186/cc12585
https://qmro.qmul.ac.uk/xmlui/handle/123456789/4380
Myers K, Hajek P, Hinds C, McRobbie H(2011). Stopping smoking shortly before surgery and postoperative complications: a systematic review and meta-analysis. Arch Intern Med vol. 171, (11) 983-989.
10.1001/archinternmed.2011.97
Walden AP, Clarke G, McKechnie S, Hutton P, Stueber F, Hinds C, Garrard C, GenOSept (2010). EPIDEMIOLOGY OF COMMUNITY ACQUIRED PENUMONIA IN THE GENOSEPT COHORT. INTENSIVE CARE MEDICINE. vol. 36, S231-S231.
Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds CH, Pearse RM (2010). A randomised controlled trial of the effects of three haemodynamic therapies on microvascular flow, tissue oxygenation and inflammatory markers after major abdominal surgery. Journal of the Intensive Care Society. Conference: The Intensive Care Society State of the Art Meeting (London) from: 14/12/2009 to: 15/12/2009, vol. 11, 60-60.
Bangash MN, Patel NS, Hinds CJ, Lever R, Thiemermann C, Pearse RM (2010). Dose-dependent effects of dopexamine on indices of shock and organ dysfunction in a rodent model of laparotomy and endoxaemia. http://journal.ics.ac.uk/pdf/1101054.pdf. Conference: The Intensive Care Society State of the Art Meeting (London) from: 14/12/2009 to: 15/12/2009, vol. 11, 64-64.
Radhakrishnan J, Svoren E, Ellis P, Langford C, Hutton P, Garrard C, Hinds CJ, Knight J et al. (2010). Evolution of gene expression signatures in septic shock due to community-acquired pneumonia. http://www.ics.ac.uk/Meetings_Seminars/ics_past_events/complete_soa09_delegate_handbook. Conference: The Intensive Care Society State of The Art Meeting (London) from: 14/12/2009 to: 14/12/2010, vol. 11, 60-60.
Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds CJ, Pearse RM(2010). Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial. Crit Care vol. 14, (4)
10.1186/cc9220
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11486
Svoren E, Radhakrishnan J, Ellis P, Langford C, Knight JC, Hinds CJ (2010). Sequential gene expression profiles following cardiac surgery involving cardiopulmonary bypass. http://www.ics.ac.uk/Meetings_Seminars/ics_past_events/complete_soa09_delegate_handbook. Conference: The Intensive Care Society State of the Art Meeting (London) from: 14/12/2009 to: 15/12/2009, vol. 11, 67-67.
Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds CJ, Pearse RM (2009). A RANDOMISED CONTROLLED TRIAL OF THE EFFECTS OF POST-OPERATIVE HAEMODYNAMIC OPTIMISATION ON MICROVASCULAR FLOW, TISSUE OXYGENATION AND INFLAMMATORY MARKERS AFTER MAJOR ABDOMINAL SURGERY. INTENSIVE CARE MEDICINE. vol. 35, 213-213.
Hinds CJ, Watson D(2009). Intensive Care Medicine. Kumar & Clark's clinical medicine, Editors: Kumar, P, Clark, ML, Saunders Ltd
Jhanji S, Stirling S, Patel N, Hinds CJ, Pearse RM(2009). The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock. Crit Care Med vol. 37, (6) 1961-1966.
10.1097/CCM.0b013e3181a00a1c
Jhanji S, Lee C, Watson D, Hinds C, Pearse RM(2009). Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications. Intensive Care Med vol. 35, (4) 671-677.
10.1007/s00134-008-1325-z
Jhanji S, Lee C, Watson D, Hinds CJ, Pearse RM (2009). Alterations in microvascular flow and tissue oxygenation after major abdominal surgery. Intensive Care Medicine. Conference: The Intensive Care Society State of the Art Meeting (London) from: 15/12/2008 to: 16/12/2008, vol. 35, 671-677.
10.1007/s00134-008-1325-z
Maddison B, Wolff C, Findlay G, Radermacher P, Hinds C, Pearse RM(2009). Comparison of three methods of extravascular lung water volume measurement in patients after cardiac surgery. Crit Care vol. 13, (4)
10.1186/cc7948
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11481
Jhanji S, Stirling S, Patel NSA, Hinds CJ, Pearse RM (2009). EFFECT OF INCREASING DOSES OF NOREPINEPHRINE ON TISSUE OXYGENATION AND MICROVASCULAR PERFUSION IN SEPTIC SHOCK. SHOCK. vol. 32, 2-2.
Jhanji S, Stirling S, Patel N, Hinds CJ, Pearse RM (2009). Effect of increasing doses of noradrenaline on microvascular perfusion and tissue oxygenation in septic shock. Critical Care Medicine. Conference: The Intensive Care Society State of the Art Meeting (London) from: 15/12/2008 to: 16/12/2008, vol. 37, 1961-1966.
10.1097/CCM.0b013e3181a00a1c
Agha-Jaffar R, Hinds CJ(2009). Growth hormone and multiple organ dysfunction syndrome. Journal of Organ Dysfunction vol. 5, (1) 17-25.
Maddison B, Giudici R, Calzia E, Wolff C, Hinds C, Radermacher P, Pearse RM(2008). Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry. Intensive Care Med vol. 34, (11) 2106-2111.
10.1007/s00134-008-1207-4
Hinds CJ, Watson D(2008). Intensive Care: A Concise Textbook. Saunders Ltd (Edinburgh),
Eisen DP, Dean MM, Boermeester MA, Fidler KJ, Gordon AC, Kronborg G, Kun JFJ, Lau YL et al.(2008). Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infection. CLIN INFECT DIS vol. 47, (4) 510-516.
10.1086/590006
Jhanji S, Thomas B, Ely A, Watson D, Hinds CJ, Pearse RM(2008). Mortality and utilisation of critical care resources amongst high-risk surgical patients in a large NHS trust. Anaesthesia vol. 63, (7) 695-700.
10.1111/j.1365-2044.2008.05560.x
Gordon A, Knight JC, Hinds CJ(2008). Genes and sepsis: How tight is the fit?. CRIT CARE MED vol. 36, (5) 1652-1654.
10.1097/CCM.0b013e318170f358
Jhanji S, Stirling S, Patel N, Hinds CJ, Pearse RM (2008). Alterations in tissue oxygenation and microvascular flow during and after major abdominal surgery. Intensive Care Medicine. Conference: European Society of Intensive Care Medicine 21st Annual Congress (Lisbon) from: 21/09/2008 to: 24/09/2008, vol. 34(Suppl. 1), S150-S150.
Yasin M, Sivarajah A, Klaus R, Felsman K, Kieswich JE, Yaqoob MM, Hinds CJ, Bauer M et al. (2008). Clondine Pre-treatment inhibits mitochondrial kapt channels and modulates the cardaic transcriptome to augment acute myocardial ischaemia reperfusion injury: A biphasic response. Intensive Care Medicine. Conference: European Society of Intensive Care Medicine 21st Annual Congress from: 21/09/2008 to: 24/09/2008, vol. 34(Suppl. 1), S160-S160.
Maddison B, Findlay G, Radermacher P, Hinds C, Pearse RM (2008). Intrathoracic blood volume measurement: A comparison of transpulmonary lithium indicator dilution with indocyanine green indicator dilution. SHOCK. vol. 29, 63-63.
Ravic N, Tucker AT, Wareham DW, Johnston A, Hinds CJ (2007). A study of novel oxides of nitrogen generating solution to prevent microbial colonization and ventilator associated pneumonia (VAP). BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. vol. 63, 781-781.
Hadley JS, Wang JE, Michaels LC, Dempsey CM, Foster SJ, Thiemermann C, Hinds CJ(2007). Alterations in inflammatory capacity and TLR expression on monocytes and neutrophils after cardiopulmonary bypass. Shock vol. 27, (5) 466-473.
10.1097/01.shk.0000245033.69977.c5
Garrard CS, Hinds CJ, Knight JC(2007). Applications in critical care medicine. Genomics and Clinical Medicine, Editors: Kumar, D, Weatherell, D, Oxford University Press
Murch O, Collin M, Hinds CJ, Thiemermann C(2007). Lipoproteins in inflammation and sepsis. I. Basic science. INTENS CARE MED vol. 33, (1) 13-24.
10.1007/s00134-006-0432-y
HINDS CJ, Thiermermann C, Foster SJ, Dempsey CM, Wang JE, Michaels LC, Hadley JS(2006). Alterations in inflammatory capacity and TLR expression on monocytes and neutrophils following cardiopulmonary bypass. Shock
Pearse RM, Harrison DA, James P, Watson D, Hinds C, Rhodes A, Grounds RM, Bennett ED(2006). Identification and characterisation of the high-risk surgical population in the United Kingdom. CRIT CARE vol. 10, (3) Article R81,
10.1186/cc4928
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9888
Gordon AC, Waheed U, Hansen TK, Hitman GA, Garrard CS, Turner MW, Klein NJ, Brett SJ et al.(2006). Mannose-binding lectin polymorphisms in severe sepsis: relationship to levels, incidence, and outcome. Shock vol. 25, (1) 88-93.
10.1097/01.shk.0000186928.57109.8d
Pearse RM, Hinds CJ(2006). Should we use central venous saturation to guide management in high-risk surgical patients?. Crit Care vol. 10, (6)
10.1186/cc5122
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11479
Teng Chung T, Hinds CJ(2006). Treatment with GH and IGF-1 in critical illness. Crit Care Clin vol. 22, (1) 29-vi.
10.1016/j.ccc.2005.09.003
Hadley JS, Wang JE, Foster SJ, Thiemermann C, Hinds CJ(2005). Peptidoglycan of Staphylococcus aureus upregulates monocyte expression of CD14, toll-like receptor 2 (TLR2), and TLR4 in human blood: Possible implications for priming of lipopolysaccharide signaling. INFECT IMMUN vol. 73, (11) 7613-7619.
10.1128/IAI.73.11.7613-7619.2005
Gordon AC, Oakervee HE, Kaya B, Thomas JM, Barnett MJ, Rohatiner AZS, Lister TA, Cavenagh JD et al. (2005). Incidence and outcome of critical illness amongst hospitalised patients with haematological malignancy: a prospective observational study of ward and intensive care unit based care. Anaesthesia. vol. 60, 340-347.
10.1111/j.1365-2044.2005.04139.x
Gordon AC, Oakervee HE, Kaya B, Thomas JM, Barnett MJ, AZS R, Lister TA, Cavenagh JD et al.(2005). Incidence and outcome of critical illness amongst hospitalised patients with haematological malignancy: a prospective observational study of ward and intensive care unit based care. Anaesthesia vol. 60, (4) 340-347.
10.1111/j.1365-2044.2005.04139.x
Hinds CJ, Watson JD(2005). Intensive Care Medicine. Kumar and Clark clinical medicine, Editors: Kumar, PJ, Clark, ML, Saunders
Hadley JS, Wang JE, Michaels LC, Foster SJ, Thiemermann C, Hinds CJ (2005). The effect of cardiopulmonary bypass (CPB) on monocyte receptor expression and ex vivo cytokine production. SHOCK. vol. 23, 72-72.
Gordon AC, Lagan AL, Aganna E, Cheung L, Peters CJ, McDermott MF, Millo JL, Welsh KI et al.(2004). TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study. GENES IMMUN vol. 5, (8) 631-640.
10.1038/sj.gene.6364136
Carlet J, Thijs LG, Antonelli M, Cassell J, Cox P, Hill N, Hinds C, Pimentel JM et al.(2004). Challenges in end-of-life care in the ICU - Statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003. INTENS CARE MED vol. 30, (5) 770-784.
10.1007/s00134-004-2241-5
Wu AH, Hinds CJ, Thiemermann C(2004). High-density lipoproteins in sepsis and septic shock: Metabolism, actions, and therapeutic applications. SHOCK vol. 21, (3) 210-221.
10.1097/01.shk.0000111661.09279.82
Hadley JS, Wang JE, Foster SJ, Thiemermann C, Hinds CJ (2004). Cytokine responses to combined administration of lipopolysaccharide (LPS) and peptidoglycan (PepG). SHOCK. vol. 21, 50-50.
10.1097/00024382-200403001-00197
HINDS CJ, Carle J, Thijs LG, Reinhart K, Sibbald WB, Taylor Thompson B, Pimentel J, Cox P et al.(2004). International Consensus Conference on challenges in end of life care. Statement of the 5th International Consensus Conference in Critical Care. Crit care med vol. 32, 1781-1784.
Hadley JS, Wang JE, Foster SJ, Thiemermann C, Hinds CJ (2004). Monocyte cell surface receptor upregulation in response to stimulation with lipopolysaccharide and peptidoglycan. SHOCK. vol. 21, 21-21.
10.1097/00024382-200403001-00084
O'Leary MJ, Koll M, Ferguson CN, Coakley JH, Hinds CJ, Preedy VR, Garlick PJ(2003). Liver albumin synthesis in sepsis in the rat: influence of parenteral nutrition, glutamine and growth hormone. CLIN SCI vol. 105, (6) 691-698.
10.1042/CS20030128
McDonald MC, Dhadly P, Cockerill GW, Cuzzocrea S, Mota-Filipe H, Hinds CJ, Miller NE, Thiemermann C(2003). Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxic shock. SHOCK vol. 20, (6) 551-557.
10.1097/01.shk.0000097249.97298.a3
Fletcher SN, Kennedy DD, Ghosh IR, Misra VP, Kiff K, Coakley JH, Hinds CJ(2003). Persistent neuromuscular and neurophysiologic abnormalities in long-term survivors of prolonged critical illness. CRIT CARE MED vol. 31, (4) 1012-1016.
10.1097/01.CCM.0000053651.38421.D9
Peters CJ, Aganna E, Nanjee MN, Cheung L, Gordon AC, Piper RD, Hitman G, Miller NE et al. (2003). Relationship of paraoxonase 1 R/Q polymorphism to outcome from severe sepsis and septic shock. BRITISH JOURNAL OF ANAESTHESIA. vol. 90, 539P-539P.
Makings E, Hinds CJ(2003). Monitoring. Classic Papers in Critical Care, Editors: Fink, M, Hayes, M, Soni, N, Blaydon Medial Publishing
McDonald MC, Dhadly P, Cockerill GW, Cuzzocrea S, Mota-Filipe H, Hinds CJ, Miller NE, Thiemermann C(2003). Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxic shock. Shock vol. 20, 551-557.
Hadley JS, Hinds CJ(2002). Anabolic strategies in critical illness. CURR OPIN PHARMACOL vol. 2, (6) 700-707.
10.1016/s1471-4892(02)00217-5
Oakervee HE, Gordon AC, Kaya B, Taussig DC, Lockley M, Barnett MJ, Rohatiner AZS, Lister TA et al. (2002). Outcomes of critical illness in patients with haematological malignancy. BLOOD. vol. 100, 875A-876A.
Gordon AC, Oakervee HE, Kaya B, Barnett MJ, Rohatiner AZ, Lister TA, Watson JD, Cavenagh JD et al. (2002). A prospective study of the incidence and outcome of critical illness in a haemato-oncology unit. INTENSIVE CARE MEDICINE. vol. 28, S46-S46.
O'Leary MJ, Ferguson CN, Coakley JH, Hinds CJ, Preedy VR(2002). Influence of starvation, surgery, and sepsis on cardiac protein synthesis in rats: Effects of parenteral nutrition, glutamine, and growth hormone. SHOCK vol. 18, (3) 265-271.
10.1097/00024382-200209000-00011
Gordon AC, Cheung L, Aganna E, Peters CJ, McDermott MF, Hitman GA, Piper RD, Hinds CJ (2002). Lack of association between the-308 TNF promoter polymorphism & outcome from sepsis & septic shock. INTENSIVE CARE MEDICINE. vol. 28, S99-S99.
Peters CJ, Nanjee MN, Gordon AC, Miller NE, Hinds CJ (2002). Modification of High Density Lipoprotein in septic shock: relationship to outcome. INTENSIVE CARE MEDICINE. vol. 28, S97-S97.
Gordon AC, Aganna E, Cheung L, Peters CJ, Piper RD, Mirakian RM, McDermott MF, Hitman GA et al. (2002). Polymorphisms of the TNFRSF1B gene: Relationship to outcome from severe sepsis and septic shock. INTENSIVE CARE MEDICINE. vol. 28, S99-S99.
Makings EA, Beddow ECL, Wilkes M, Patel M, Hadley J, Benjamin N, Hinds CJ(2002). Decreased intragastric production of nitric oxide could predispose to ventilator-associated pneumonia. BRIT J ANAESTH vol. 89, (2) 356P-356P.
Peters CJ, Nanjee MN, Gordon AC, Miller NE, Hinds CJ(2002). Proinflammatory modifications of lipoprotein structure and function in patients with septic shock: relationship to outcome. BRIT J ANAESTH vol. 89, (2) 361P-361P.
O'Leary MJ, Ferguson CN, Rennie M, Hinds CJ, Coakley JH, Preedy VR(2002). Effect of growth hormone on muscle and liver protein synthesis in septic rats receiving glutamine-enriched parenteral nutrition. CRIT CARE MED vol. 30, (5) 1099-1105.
10.1097/00003246-200205000-00023
Smith PJ, Spurrell EL, Coakley J, Hinds CJ, Ross RJM, Krainer AR, Chew SL(2002). An exonic splicing enhancer in human IGF-I pre-mRNA mediates recognition of alternative exon 5 by the serine-arginine protein splicing factor-2/alternative splicing factor. ENDOCRINOLOGY vol. 143, (1) 146-154.
10.1210/endo.143.1.8598
Hinds CJ, Watson JD(2002). Intensive Care Medicine. Kumar & Clark clinical medicine, Editors: Kumar, PJ, Kumar, P, Clark, ML, W B Saunders Co
Hinds CJ(2001). Treatment of sepsis with activated protein C - Encouraging news for well selected patients. BRIT MED J vol. 323, (7318) 881-882.
10.1136/bmj.323.7318.881
O'Leary MJ, Koll M, Ferguson CN, Ahmed S, Mantle D, Hinds CJ, Coakley JH(2001). Influence of nutrition, glutamine and growth hormone on skeletal muscle protease activity in septic rats. INTENS CARE MED vol. 27, S205-S205.
O'Leary MJ, Ferguson CN, Rennie MJ, Hinds CJ, Coakley JH, Preedy VR(2001). Sequential changes in in vivo muscle and liver protein synthesis and plasma and tissue glutamine levels in sepsis in the rat. CLIN SCI vol. 101, (3) 295-304.
10.1042/CS20010115
O'Leary MJ, Koll M, Ferguson CN, Ahmed S, Mantle D, Hinds CJ, Coakley JH, Preedy VR(2001). Skeletal muscle lysosomal protease activity in septic rats. INTENS CARE MED vol. 27, S205-S205.
Johnson TS, O'Leary M, Justice SK, Maamra M, Zarkesh-Esfahani SH, Furlanetto R, Preedy VR, Hinds CJ et al.(2001). Differential expression of suppressors of cytokine signalling genes in response to nutrition and growth hormone in the septic rat. J ENDOCRINOL vol. 169, (2) 409-415.
10.1677/joe.0.1690409
Wray GM, Foster SJ, Hinds CJ, Thiemermann C(2001). A cell wall component from pathogenic and non-pathogenic gram-positive bacteria (peptidoglycan) synergises with endotoxin to cause the release of tumour necrosis factor-alpha, nitric oxide production, shock, and multiple organ injury/dysfunction in the rat. SHOCK vol. 15, (2) 135-142.
10.1097/00024382-200115020-00010
Ghosh IR, Kennedy DD, Fleter SN, Misra VP, Coakley JH, Hinds CJ(2001). Identical persisting neurophysiological features of chronic denervation found in four cases of resolved critical illness motor syndrome. Clinical Intensive Care vol. 12, 229-236.
Hinds CJ, Watson D(1999). ABC of intensive care: Circulatory support. British Medical Journal vol. 318, (7200) 1749-1752.
10.1136/bmj.318.7200.1749
Hinds CJ, Fletcher SN(1999). Ranitidine reduced clinically important gastrointestinal bleeding in patients who required mechanical ventilation. Gut vol. 44, (1) 10-11.
10.1136/gut.44.1.10
Drake WM, Perry LA, Hinds CJ, Lowe DG, Reznek RH, Besser GM(1998). Emergency and prolonged use of intravenous etomidate to control hypercortisolemia in a patient with Cushing's syndrome and peritonitis. Journal of Clinical Endocrinology and Metabolism vol. 83, (10) 3542-3544.
10.1210/jc.83.10.3542
Wray GM, Hinds CJ, Thiemermann C(1998). Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin. Shock vol. 10, (1) 13-19.
10.1097/00024382-199807000-00003
Wray GM, Millar CG, Hinds CJ, Thiemermann C(1998). Selective inhibition of the activity of inducible nitric oxide synthase prevents the circulatory failure, but not the organ injury/dysfunction, caused by endotoxin. Shock vol. 9, (5) 329-335.
10.1097/00024382-199805000-00003
Hayes MA, Timmins AC, Yau EH, Palazzo M, Watson D, Hinds CJ(1997). Oxygen transport patterns in patients with sepsis syndrome or septic shock: influence of treatment and relationship to outcome. Crit Care Med vol. 25, (6) 926-936.
10.1097/00003246-199706000-00007
Hinds C, Watson D(1995). Manipulating hemodynamics and oxygen transport in critically ill patients. N Engl J Med vol. 333, (16) 1074-1075.
10.1056/NEJM199510193331609
Pick B, Molloy A, Hinds C, Pearce S, Salmon P(1994). Post-operative fatigue following coronary artery bypass surgery: relationship to emotional state and to the catecholamine response to surgery. J Psychosom Res vol. 38, (6) 599-607.
10.1016/0022-3999(94)90057-4
Hayes MA, Timmins AC, Yau EH, Palazzo M, Hinds CJ, Watson D(1994). Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med vol. 330, (24) 1717-1722.
10.1056/NEJM199406163302404
Hayes MA, Yau EH, Timmins AC, Hinds CJ, Watson D(1993). Response of critically ill patients to treatment aimed at achieving supranormal oxygen delivery and consumption. Relationship to outcome. Chest vol. 103, (3) 886-895.
10.1378/chest.103.3.886
Donaldson MD, Vesey CJ, Wilks M, Watson JD, Hinds CJ(1991). Lack of effect of ACTH in porcine Escherichia coli septic shock. Circ Shock vol. 35, (3) 152-158.
Amos RJ, Deane M, Ferguson C, Jeffries G, Hinds CJ, Amess JA(1990). Observations on the haemopoietic response to critical illness. J Clin Pathol vol. 43, (10) 850-856.
10.1136/jcp.43.10.850
Watson JD, Sury MR, Corder R, Carson R, Bouloux PM, Lowry PJ, Besser GM, Hinds CJ(1988). Plasma levels of neuropeptide tyrosine Y (NPY) are increased in human sepsis but are unchanged during canine endotoxin shock despite raised catecholamine concentrations. J Endocrinol vol. 116, (3) 421-426.
10.1677/joe.0.1160421
Donaldson MDJ, Vesey CJ, Wilks M, Hinds CJ(1988). Beneficial effect of buprenorphine (a partial opiate agonist) in porcine Escherichia coli septicaemia: A comparison with naloxone. Circulatory Shock vol. 25, (3) 209-221.
Amos RJ, Kirk B, Amess JAL, Jones AL, Hinds CJ(1987). Bone marrow hypoplasia during intensive care: bone marrow culture studies implicating ranitidine in the suppression of haemopoiesis. Human Toxicology vol. 6, (6) 503-506.
10.1177/096032718700600609
Amos RJ, Amess JA, Hinds CJ, Mollin DL(1985). Investigations into the effect of nitrous oxide anaesthesia on folate metabolism in patients receiving intensive care. Chemioterapia vol. 4, (5) 393-399.
Prior JG, Hinds CJ, Williams J, Prior PF(1983). The use of etomidate in the management of severe head injury. Intensive Care Med vol. 9, (6) 313-320.
10.1007/BF01692549
Amos RJ, Amess JA, Hinds CJ, Mollin DL(1982). Incidence and pathogenesis of acute megaloblastic bone-marrow change in patients receiving intensive care. Lancet vol. 2, (8303) 835-838.
10.1016/s0140-6736(82)90808-x
Hinds CJ, Ingram D, Adams L, Cole PV, Dickinson CJ, Kay J, Krapez JR, Williams J(1980). An evaluation of the clinical potential of a comprehensive model of human respiration in artificially ventilated patients. Clin Sci (Lond) vol. 58, (1) 83-91.
10.1042/cs0580083
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