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Publications:  Prof John Gribben

Flinn IW, Gribben JG, Dyer MJS, Wierda W, Maris MB, Furman RR, Hillmen P, Rogers KA et al.(2019). Phase 1b study of venetoclax-obinutuzumab in previously untreated and relapsed/refractory chronic lymphocytic leukemia. Blood vol. 133, (26) 2765-2775.
10.1182/blood-2019-01-896290
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al.(2019). Correction: Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma. Leukemia vol. 33, (6)
10.1038/s41375-019-0425-9
Gruber M, Bozic I, Leshchiner I, Livitz D, Stevenson K, Rassenti L, Rosebrock D, Taylor-Weiner A et al.(2019). Growth dynamics in naturally progressing chronic lymphocytic leukaemia. Nature vol. 570, (7762) 474-479.
10.1038/s41586-019-1252-x
Snowden JA, Hawkey C, Hind D, Swaby L, Mellor K, Emsley R, Mandefield L, Lee E et al.(2019). Autologous stem cell transplantation in refractory Crohn's disease - low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study. BMC Gastroenterol vol. 19, (1)
10.1186/s12876-019-0992-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58514
Leonard JP, Trneny M, Izutsu K, Fowler NH, Hong X, Zhu J, Zhang H, Offner F et al.(2019). AUGMENT: A Phase III Study of Lenalidomide Plus Rituximab Versus Placebo Plus Rituximab in Relapsed or Refractory Indolent Lymphoma. J Clin Oncol vol. 37, (14) 1188-1199.
10.1200/JCO.19.00010
Potter N, Miraki-Moud F, Ermini L, Titley I, Vijayaraghavan G, Papaemmanuil E, Campbell P, Gribben J et al.(2019). Single cell analysis of clonal architecture in acute myeloid leukaemia. Leukemia vol. 33, (5) 1113-1123.
10.1038/s41375-018-0319-2
Sun D, Stopka-Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkämper A, Capasso M, Wan X et al.(2019). Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation. Cell Rep vol. 27, (5) 1461-1471.e4.
10.1016/j.celrep.2019.04.014
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57415
Zhang T, Guan X-W, Gribben JG, Liu F-T, Jia L(2019). Blockade of HMGB1 signaling pathway by ethyl pyruvate inhibits tumor growth in diffuse large B-cell lymphoma. Cell Death Dis vol. 10, (5)
10.1038/s41419-019-1563-8
Baptista MJ, Tapia G, Morgades M, Muncunill J, Muñoz-Marmol A-M, Montoto S, Gribben JG, Calaminici M et al.(2019). Using the Lymph2Cx assay for assessing cell-of-origin subtypes of HIV-related diffuse large B-cell lymphoma. Leuk Lymphoma vol. 60, (4) 1087-1091.
10.1080/10428194.2018.1512711
Goulart MR, Hlavaty SI, Chang Y-M, Polton G, Stell A, Perry J, Wu Y, Sharma E et al.(2019). Phenotypic and transcriptomic characterization of canine myeloid-derived suppressor cells. Sci Rep vol. 9, (1)
10.1038/s41598-019-40285-3
Moreno C, Greil R, Demirkan F, Tedeschi A, Anz B, Larratt L, Simkovic M, Samoilova O et al.(2019). Ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab in first-line treatment of chronic lymphocytic leukaemia (iLLUMINATE): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol vol. 20, (1) 43-56.
10.1016/S1470-2045(18)30788-5
Taylor JG, Clear A, Calaminici M, Gribben JG(2019). Programmed cell death protein-1 (PD1) expression in the microenvironment of classical Hodgkin lymphoma is similar between favorable and adverse outcome and does not enrich over serial relapses with conventional chemotherapy. Haematologica vol. 104, (1) e42-e44.
10.3324/haematol.2018.204818
Thanarajasingam G, Minasian LM, Baron F, Cavalli F, De Claro RA, Dueck AC, El-Galaly TC, Everest N et al.(2018). Beyond maximum grade: modernising the assessment and reporting of adverse events in haematological malignancies. Lancet Haematol vol. 5, (11) e563-e598.
10.1016/S2352-3026(18)30051-6
Robak T, Burger JA, Tedeschi A, Barr PM, Owen C, Bairey O, Hillmen P, Simpson D et al.(2018). Single-agent ibrutinib versus chemoimmunotherapy regimens for treatment-naïve patients with chronic lymphocytic leukemia: A cross-trial comparison of phase 3 studies. Am J Hematol vol. 93, (11) 1402-1410.
10.1002/ajh.25259
Gribben JG(2018). No longer too exhausted to run. Blood vol. 132, (5) 464-465.
10.1182/blood-2018-06-851642
Cheson BD, Chua N, Mayer J, Dueck G, Trn¿ný M, Bouabdallah K, Fowler N, Delwail V et al.(2018). Overall Survival Benefit in Patients With Rituximab-Refractory Indolent Non-Hodgkin Lymphoma Who Received Obinutuzumab Plus Bendamustine Induction and Obinutuzumab Maintenance in the GADOLIN Study. J Clin Oncol vol. 36, (22) 2259-2266.
10.1200/JCO.2017.76.3656
Casado P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Iqbal S et al.(2018). Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells. Leukemia vol. 32, (8) 1818-1822.
10.1038/s41375-018-0032-1
Gribben JG(2018). How and when I do allogeneic transplant in CLL. Blood vol. 132, (1) 31-39.
10.1182/blood-2018-01-785998
Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al.(2018). Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma. Leukemia vol. 32, (5) 1261-1265.
10.1038/s41375-018-0043-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36269
Pockley AG, Lindsay JO, Foulds GA, Rutella S, Gribben JG, Alexander T, Snowden JA(2018). Immune Reconstitution After Autologous Hematopoietic Stem Cell Transplantation in Crohn's Disease: Current Status and Future Directions. A Review on Behalf of the EBMT Autoimmune Diseases Working Party and the Autologous Stem Cell Transplantation In Refractory CD-Low Intensity Therapy Evaluation Study Investigators. Front Immunol vol. 9, 646-646.
10.3389/fimmu.2018.00646
https://qmro.qmul.ac.uk/xmlui/handle/123456789/53523
Dürr C, Hanna BS, Schulz A, Lucas F, Zucknick M, Benner A, Clear A, Ohl S et al.(2018). Tumor necrosis factor receptor signaling is a driver of chronic lymphocytic leukemia that can be therapeutically targeted by the flavonoid wogonin. Haematologica vol. 103, (4) 688-697.
10.3324/haematol.2017.177808
Griessinger E, Vargaftig J, Horswell S, Taussig DC, Gribben J, Bonnet D(2018). Acute myeloid leukemia xenograft success prediction: Saving time. Experimental Hematology vol. 59, 66-71.e4.
10.1016/j.exphem.2017.12.002
Gribben JG, Bosch F, Cymbalista F, Geisler CH, Ghia P, Hillmen P, Moreno C, Stilgenbauer S(2018). Optimising outcomes for patients with chronic lymphocytic leukaemia on ibrutinib therapy: European recommendations for clinical practice. Br J Haematol vol. 180, (5) 666-679.
10.1111/bjh.15080
Casado P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Iqbal S et al.(2017). Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells. Leukemia
10.1038/leu.2017.349
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D et al.(2017). Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers. Cancer Discov
10.1158/2159-8290.CD-17-0284
https://qmro.qmul.ac.uk/xmlui/handle/123456789/30984
Gascoyne RD, Nadel B, Pasqualucci L, Fitzgibbon J, Payton JE, Melnick A, Weigert O, Tarte K et al.(2017). Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015. Hematol Oncol vol. 35, (4) 397-407.
10.1002/hon.2411
Di Tullio A, Rouault-Pierre K, Abarrategi A, Mian S, Grey W, Gribben J, Stewart A, Blackwood E et al.(2017). The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia. Nat Commun vol. 8, (1) 1679-1679.
10.1038/s41467-017-01834-4
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34404
Saunderson EA, Stepper P, Gomm JJ, Hoa L, Morgan A, Allen MD, Jones JL, Gribben JG et al.(2017). Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors. Nat Commun vol. 8, (1)
10.1038/s41467-017-01078-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/29503
DAVIES JK, Hassan S, Sarker S, Besley C, Oakervee H, Smith M, Taussig D, Gribben JG et al.(2017). Durable graft-versus-leukaemia effects without donor lymphocyte infusions- results of a Phase II study of sequential T-replete allogeneic transplantation for high-risk acute myeloid leukaemia and myelodysplasia. British Journal of Haematology
10.1111/bjh.14980
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25815
Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A et al.(2017). Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma. Cell vol. 171, (2) 481-494.e15.
10.1016/j.cell.2017.09.027
Munir T, Howard DR, McParland L, Pocock C, Rawstron AC, Hockaday A, Varghese A, Hamblin M et al.(2017). Results of the randomized phase IIB ADMIRE trial of FCR with or without mitoxantrone in previously untreated CLL. Leukemia vol. 31, (10) 2085-2093.
10.1038/leu.2017.65
Passaro D, Di Tullio A, Abarrategi A, Rouault-Pierre K, Foster K, Ariza-McNaughton L, Montaner B, Chakravarty P et al.(2017). Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia. Cancer Cell vol. 32, (3) 324-341.e6.
10.1016/j.ccell.2017.08.001
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34506
Klymenko T, Bloehdorn J, Bahlo J, Robrecht S, Akylzhanova G, Cox K, Estenfelder S, Wang J et al.(2017). Lamin B1 regulates somatic mutations and progression of B-cell malignancies. Leukemia vol. 32, (2) 364-375.
10.1038/leu.2017.255
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54655
Stevens WBC, Mendeville M, Redd R, Clear AJ, Bladergroen R, Calaminici M, Rosenwald A, Hoster E et al.(2017). Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium. Haematologica vol. 102, (8) 1413-1423.
10.3324/haematol.2017.165415
Bento L, Boumendil A, Finel H, Le Gouill S, Amorim S, Monjanel H, Bouabdallah R, Bay JO et al.(2017). Radioimmunotherapy-augmented BEAM chemotherapy vs BEAM alone as the high-dose regimen for autologous stem cell transplantation (ASCT) in relapsed follicular lymphoma (FL): a retrospective study of the EBMT Lymphoma Working Party. Bone Marrow Transplant vol. 52, (8) 1120-1125.
10.1038/bmt.2017.88
Younes A, Hilden P, Coiffier B, Hagenbeek A, Salles G, Wilson W, Seymour JF, Kelly K et al.(2017). International Working Group consensus response evaluation criteria in lymphoma (RECIL 2017). Ann Oncol vol. 28, (7) 1436-1447.
10.1093/annonc/mdx097
Passaro D, Di Tullio A, Abarrategi A, Rouault-Pierre K, Foster K, Ariza-McNaughton L, Chakravarty P, Bhaw L et al. (2017). ACUTE MYELOID LEUKEMIA ALTERS THE PERMEABILITY OF THE BONE MARROW VASCULAR MICROENVIRONMENT, FOSTERING DISEASE PROGRESSION AND DRUG RESISTANCE. HAEMATOLOGICA. vol. 102, 78-78.
Besley C, Kotsiou E, Petty R, Sangaralingam A, Chelala C, Ghazaly E, LeDieu R, Gribben J et al. (2017). ALLORESPONSES OF HUMAN T-CELLS FROM ADULT PERIPHERAL BLOOD AND UMBILICAL CORD BLOOD ARE DIFFERENTIALLY IMPACTED BY LENALIDOMIDE - IMPLICATIONS FOR AHSCT. HAEMATOLOGICA. vol. 102, 638-638.
Seymour F, Cavenagh J, Gribben J (2017). CYTOTOXIC LYMPHOCYTES IN NEWLY DIAGNOSED MYELOMA HAVE REVERSIBLE FUNCTIONAL AND PHENOTYPIC ABNORMALITIES THAT MAY OFFER THERAPUTIC OPPORTUNITIES. HAEMATOLOGICA. vol. 102, 498-498.
Vilventhraraja E, Gribben J, Braun A (2017). INTRACELLULAR CALCIUM AND METABOLISM HAVE CRITICAL ROLES IN DETERMINING ANTI-CD20 ANTIBODY EFFICACY IN DLBCL. HAEMATOLOGICA. vol. 102, 567-567.
Dokal A, Gribben J, Cutillas P (2017). MICROENVIRONMENT SECRETED PROTEINS MEDIATE RESISTANCE TO TARGETED THERAPY IN PRIMARY AML CELLS. HAEMATOLOGICA. vol. 102, 358-358.
Klymenko T, Bloehdorn J, Bahlo J, Robrecht S, Wang J, Fischer K, Akylzhanova G, Edelmann J et al. (2017). NUCLEAR LAMINA REGULATES SOMATIC HYPERMUTATION AND PROGRESSION OF B CELL MALIGNANCIES. HAEMATOLOGICA. vol. 102, 228-228.
Casado-Izquierdo P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Sameena I et al. (2017). PHOSPHOPROTEOMICS AND MASS CYTOMETRY SIGNATURES OF PRIMARY AML CELL DIFFERENTIATION ARE ASSOCIATED WITH SENSITIVITY TO KINASE INHIBITORS. HAEMATOLOGICA. vol. 102, 203-203.
Hillmen P, Rawstron A, Munir T, Brock K, Vincente SM, Jefferson Y, Paterson K, Fox CP et al. (2017). THE INITIAL REPORT OF THE BLOODWISE TAP CLARITY STUDY COMBINING IBRUTINIB AND VENETOCLAX IN RELAPSED, REFRACTORY CLL SHOWS ACCEPTABLE SAFETY AND PROMISING EARLY INDICATIONS OF EFFICACY. HAEMATOLOGICA. vol. 102, 311-311.
Gribben JG(2017). Restoring leukemia cell function from the inside out. Blood vol. 129, (24) 3137-3138.
10.1182/blood-2017-04-776344
Edelmann J, Gribben JG(2017). Managing Patients With TP53-Deficient Chronic Lymphocytic Leukemia. J Oncol Pract vol. 13, (6) 371-377.
10.1200/JOP.2017.023291
Gribben JG(2017). The role of stem cell transplant for lymphoma in 2017. Hematol Oncol vol. 35 Suppl 1, 25-29.
10.1002/hon.2396
Duncan M, Deane J, White PD, Ridge D, Roylance R, Korszun A, Chalder T, Bhui KS et al.(2017). A survey to determine usual care after cancer treatment within the United Kingdom National Health Service. BMC Cancer vol. 17, (186)
10.1186/s12885-017-3172-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/20541
Edelmann J, Tausch E, Landau DA, Robrecht S, Bahlo J, Fischer K, Fink AM, Bloehdorn J et al.(2017). Frequent evolution of copy number alterations in CLL following first-line treatment with FC(R) is enriched with TP53 alterations: results from the CLL8 trial. Leukemia vol. 31, (3) 734-738.
10.1038/leu.2016.317
Abarrategi A, Foster K, Hamilton A, Mian SA, Passaro D, Gribben J, Mufti G, Bonnet D(2017). Versatile humanized niche model enables study of normal and malignant human hematopoiesis. J Clin Invest vol. 127, (2) 543-548.
10.1172/JCI89364
Chanan-Khan A, Egyed M, Robak T, Martinelli de Oliveira FA, Echeveste MA, Dolan S, Desjardins P, Blonski JZ et al.(2017). Randomized phase 3 study of lenalidomide versus chlorambucil as first-line therapy for older patients with chronic lymphocytic leukemia (the ORIGIN trial). Leukemia vol. 31, (5) 1240-1243.
10.1038/leu.2017.47
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35464
Lucas FM, Gribben JG(2017). Aberrant Immunological Synapses Driven by Leukemic Antigen-Presenting Cells. Methods Mol Biol vol. 1584, 533-544.
10.1007/978-1-4939-6881-7_33
Dermit M, Casado P, Rajeeve V, Wilkes EH, Foxler DE, Campbell H, Critchlow S, Sharp TV et al.(2016). Oxidative stress downstream of mTORC1 but not AKT causes a proliferative defect in cancer cells resistant to PI3K inhibition. Oncogene
10.1038/onc.2016.435
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19702
Besley C, Kotsiou E, Petty R, Ajanthah S, Chelala C, Ghazaly E, Le Dieu R, Davies J et al. (2016). Alloresponses of Human T-Cells from Adult Peripheral Blood and Umbilical Cord Blood Are Differentially Impacted By Lenalidomide. BLOOD. vol. 128,
Casado P, Wilkes E, Hadi MM, Rajeeve V, Miraki-Moud F, Pike R, Del Rio-Machin A, Iqbal S et al. (2016). Differentiation Status Revealed By Shotgun Phosphoproteomics Determines Sensitivity of Primary AML Cells to Kinase Inhibitors. BLOOD. vol. 128,
Kharfan-Dabaja MA, Kumar A, Hamadani M, Stilgenbauer S, Ghia P, Anasetti C, Dreger P, Montserrat E et al.(2016). Clinical Practice Recommendations for Use of Allogeneic Hematopoietic Cell Transplantation in Chronic Lymphocytic Leukemia on Behalf of the Guidelines Committee of the American Society for Blood and Marrow Transplantation. Biology of Blood and Marrow Transplantation vol. 22, (12) 2117-2125.
10.1016/j.bbmt.2016.09.013
Salzer E, Cagdas D, Hons M, Mace EM, Garncarz W, Petronczki Ö, Platzer R, Pfajfer L et al.(2016). RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics. Nature Immunology vol. 17, (12) 1352-1360.
10.1038/ni.3575
Cheson BD, Trask PC, Gribben JG, Dimier N, Kimby E, Lugtenburg PJ, Thieblemont C, Wassner-Fritsch E et al.(2016). Health-related quality of life and symptoms in patients with rituximab-refractory indolent non-Hodgkin lymphoma treated in the phase III GADOLIN study with obinutuzumab plus bendamustine versus bendamustine alone. Annals of Hematology
10.1007/s00277-016-2878-5
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19680
Sarker SJ, Smith SK, Chowdhury K, Ganz PA, Zimmerman S, Gribben J, Korszun A(2016). Comparison of the impact of cancer between British and US long-term non-Hodgkin lymphoma survivors. Supportive Care in Cancer
10.1007/s00520-016-3454-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18960
Cui B, Ghia EM, Chen L, Rassenti LZ, DeBoever C, Widhopf GF, Yu J, Neuberg DS et al.(2016). High-level ROR1 associates with accelerated disease-progression in chronic lymphocytic leukemia. Blood vol. 128, 2931-2940.
10.1182/blood-2016-04-712562
Hawkins ED, Duarte D, Akinduro O, Khorshed RA, Passaro D, Nowicka M, Straszkowski L, Scott MK et al.(2016). T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments. Nature vol. 538, (7626) 518-522.
10.1038/nature19801
McClanahan F, Sharp TG, Gribben JG(2016). Catching up with solid tumor oncology: what is the evidence for a prognostic role of programmed cell death-ligand 1/programmed cell death-1 expression in B-cell lymphomas?. Haematologica vol. 101, (10) 1144-1158.
10.3324/haematol.2016.145904
Navarro-Bailon A, Taylor JG, Matthews J, Montoto S, Gribben JG (2016). THE ROLE OF WATCH AND WAIT IN NODULAR LYMPHOCYTE PREDOMINANT HODGKIN LYMPHOMA: SINGLE CENTRE DATA FROM THE MODERN ERA. HAEMATOLOGICA. vol. 101, 64-64.
Edelmann J, Gribben JG(2016). Obinutuzumab for the treatment of indolent lymphoma. Future Oncol vol. 12, (15) 1769-1781.
10.2217/fon-2016-0084
Sehn LH, Chua N, Mayer J, Dueck G, Trn¿ný M, Bouabdallah K, Fowler N, Delwail V et al.(2016). Obinutuzumab plus bendamustine versus bendamustine monotherapy in patients with rituximab-refractory indolent non-Hodgkin lymphoma (GADOLIN): a randomised, controlled, open-label, multicentre, phase 3 trial. Lancet Oncol vol. 17, (8) 1081-1093.
10.1016/S1470-2045(16)30097-3
Freeman CL, Dixon M, Houghton R, Kreuzer K-A, Fingerle-Rowson G, Herling M, Humphrey K, Böttcher S et al.(2016). Role of CD20 expression and other pre-treatment risk factors in the development of infusion-related reactions in patients with CLL treated with obinutuzumab. Leukemia vol. 30, (8) 1763-1766.
10.1038/leu.2016.41
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28865
Kotsiou E, Okosun J, Besley C, Iqbal S, Matthews J, Fitzgibbon J, Gribben J, DAVIES JK(2016). TNFRSF14 aberrations in follicular lymphoma increase clinically significant allogeneic T-cell responses. Blood vol. 128, (1) 72-81.
10.1182/blood-2015-10-679191
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12275
Eyre TA, Clifford R, Bloor A, Boyle L, Roberts C, Cabes M, Collins GP, Devereux S et al.(2016). NCRI phase II study of CHOP in combination with ofatumumab in induction and maintenance in newly diagnosed Richter syndrome. British Journal of Haematology
10.1111/bjh.14177
Hawkey CJ, Lindsay J, Gribben J(2016). Stem Cell Transplantation for Refractory Crohn Disease--Reply. JAMA vol. 315, (23) 2620-2621.
10.1001/jama.2016.4033
Schwarzbich M-A, McClanahan F, Gribben J(2016). Allogeneic Transplantation for Chronic Lymphocytic Leukemia in the Age of Novel Treatment Strategies. Oncology (Williston Park) vol. 30, (6) 526-540.
Kotsiou E, Gribben JG, Davies JK(2016). Allospecific Tregs expanded after anergization remain suppressive in inflammatory conditions but lack expression of gut-homing molecules. Molecular therapy : the journal of the American Society of Gene Therapy vol. 24, (6) 1126-1134.
10.1038/mt.2016.64
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25657
Vilventhraraja E, Gribben J, Ivanov A (2016). EXPLOITING OXIDATIVE PHOSPHORYLATION TO IMPROVE ANTIBODY THERAPY OF LYMPHOMA. HAEMATOLOGICA. vol. 101, 574-575.
Araf S, Wang J, Pangault C, Kotsiou E, Hoxha E, Iqbal S, Davies J, Johnson P et al. (2016). GENOMIC PROFILING REVEALS SPATIAL HETEROGENEITY IN FOLLICULAR LYMPHOMA: IMPLICATIONS FOR PRECISION MEDICINE. HAEMATOLOGICA. vol. 101, 270-270.
Dokal A, Gribben J, Cutillas P (2016). HETEROTYPIC SIGNALLING BETWEEN BONE MARROW STROMAL CELLS AND BLASTS PROVIDES INSIGHT INTO THE CELLULAR COMMUNICATION IN ACUTE MYELOID LEUKAEMIA. HAEMATOLOGICA. vol. 101, 369-369.
Petty R, Zhang X, Ivan C, Calin G, Gribben J, Le Dieu R (2016). MICRORNAS HSA-LET-7A AND MIR-142-3P IN T CELLS IN PATIENTS PRESENTING WITH ACUTE MYELOID LEUKAEMIA-A MEANS OF REPAIRING TUMOUR-INDUCED T CELL DEFECTS?. HAEMATOLOGICA. vol. 101, 364-365.
Trneny M, Bouabdallah K, Dueck G, Gribben J, Lugtenburg P, Press O, Salles G, Sehn L et al. (2016). OBINUTUZUMAB PLUS BENDAMUSTINE VERSUS BENDAMUSTINE ALONE IN PATIENTS WITH RITUXIMAB-REFRACTORY FOLLICULAR LYMPHOMA: RESULTS FROM THE GADOLIN STUDY. HAEMATOLOGICA. vol. 101, 155-156.
Britton D, Casado P, Rajeeve V, Wilkes E, Smith R, Fitzgibbon J, Gribben J, Cutillas P (2016). PROTEOMIC ANALYSIS OF RELAPSE AML IDENTIFIES OPPORTUNITIES FOR THERAPEUTIC INTERVENTION IN INDIVIDUAL PATIENTS. HAEMATOLOGICA. vol. 101, 373-373.
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al.(2016). Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma (vol 48, pg 183, 2016). NATURE GENETICS vol. 48, (6) 700-700.
10.1038/ng0616-700b
Wendtner CM, Hallek M, Fraser GA, Michallet AS, Hillmen P, Dürig J, Kalaycio M, Gribben JG et al.(2016). Safety and efficacy of different lenalidomide starting doses in patients with relapsed or refractory chronic lymphocytic leukemia: results of an international multicenter double-blinded randomized phase II trial. Leukemia and Lymphoma vol. 57, (6) 1291-1299.
10.3109/10428194.2015.1128540
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Seraihi AFA et al.(2016). Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma. Nat Genet vol. 48, (6) 700-700.
10.1038/ng0616-700b
Walsh C, Bonner JJ, Johnson TN, Neuhoff S, Ghazaly EA, Gribben JG, Boddy AV, Veal GJ(2016). Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer. Br J Clin Pharmacol vol. 81, (5) 989-998.
10.1111/bcp.12878
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18499
Fowler NH, Cheah CY, Gascoyne RD, Gribben J, Neelapu SS, Ghia P, Bollard C, Ansell S et al.(2016). Role of the tumor microenvironment in mature B-cell lymphoid malignancies. Haematologica: the hematology journal vol. 101, (5) 531-540.
10.3324/haematol.2015.139493
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McClanahan F, Calore F, Zanesi N, Gribben JG, Croce CM (2014). Aberrant PD-L1 Expression in CLL As a Result of Adaptive Immune Resistance Mediated By Tumor-Secreted Circulating miRNA Binding to Toll-like Receptor 7. BLOOD. vol. 124,
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Sarker S-J, George GE, Chowdhury K, Levitt G, Kingston J, Lister A, Gribben JG, Korszun A(2014). Late Effects: An Evaluation of Contrasting Physical and Psychological Experiences Between Child and Adult Hodgkin Survivors. BLOOD vol. 124, (21)
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Besley CM, Kotsiou E, Petty R, Sangaralingum A, Le Dieu R, Gribben JG, Davies JK (2014). Lenalidomide Enhances Human Alloresponses By Increasing Proliferation of Effector Memory CD8 T Cells with Enhanced Polyfunctional Effector Capacity and a Unique Gene Expression Profile. BLOOD. vol. 124,
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Ghazaly E, Smith P, Gnanaranjan C, Young BD, Joel S, Gribben JG, Taussig DC (2014). SKIP Is Underexpressed in AML Leading to Sphingosine Kinase Hypofunction. BLOOD. vol. 124,
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Greaves P, Lister TA, Gribben JG(2014). Parenthood in long-term survivors after CHOP with or without etoposide treatment for aggressive lymphoma - response to Meissner et al. Br J Haematol vol. 166, (4) 615-616.
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Riches JC, Gribben JG(2014). Immunomodulation and immune reconstitution in chronic lymphocytic leukemia. Semin Hematol vol. 51, (3) 228-234.
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Riches JC, O'Donovan CJ, Kingdon SJ, McClanahan F, Clear AJ, Neuberg DS, Werner L, Croce CM et al.(2014). Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations. BLOOD vol. 123, (26) 4101-4110.
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Munir T, Cohen D, Pocock C, Rawstron A, McParland L, Chalmers A, Varghese A, Smith A et al. (2014). ORAL FCR INDUCES HIGHER COMPLETE REMISSION RATES AND MRD NEGATIVITY IN UNTREATED CLL THAN PREVIOUS REPORTS OF INTRAVENOUS THERAPY: COMBINED RESULTS OF THE NCRI ADMIRE AND ARCTIC TRIALS. HAEMATOLOGICA. vol. 99, 54-54.
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El-Najjar I, Boumendil A, Luan J, Thieblemont C, Blaise D, Thomson K, Mohty M, Colombat P et al. (2012). The outcome of patients with follicular lymphoma in the rituximab era treated with autologous stem cell transplant according to the high-dose regimen received. A retrospective study of the EBMT Lymphoma Working Party. BONE MARROW TRANSPLANTATION. vol. 47, S3-S4.
Jasani PD, MacDougall F, Smith MLW, Cavenagh JD, Lister TA, Gribben JG, Taussig DC, Oakervee HE (2012). Treatment of acute myeloid leukaemia in the elderly: a retrospective analysis. BRITISH JOURNAL OF HAEMATOLOGY. vol. 157, 64-65.
Wendtner C-M, Hillmen P, Mahadevan D, Buehler A, Uharek L, Coutre S, Frankfurt O, Bloor A et al.(2012). Final results of a multicenter phase 1 study of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia. LEUKEMIA & LYMPHOMA vol. 53, (3) 417-423.
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Riches JC, Ramsay AG, Gribben JG(2012). Immune dysfunction in chronic lymphocytic leukemia: the role for immunotherapy. Curr Pharm Des vol. 18, (23) 3389-3398.
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Jia L, Uddin N, Gribben JG (2011). Activation of Mitochondrial STAT3 Increases Mitochondrial Respiration and Inhibits Oxidative Stress in Chronic Lymphocytic Leukemic Cells. BLOOD. vol. 118, 133-133.
Liu F, Jia L, Farren TW, Gribben JG, Agrawal SG (2011). Autocrine IL-6 Production Indicates the Level of Activated STAT3 and NF-Kb of Chronic Lymphocytic Leukemia Cells. BLOOD. vol. 118, 778-778.
Xing D, Ramsay AG, Decker W, Lee DA, Robinson S, Shah N, Parmar S, Bollard CM et al. (2011). CD137L Reverse the Immunological Synapse Defects of Natural Killer Cells in Acute Myeloid Leukemia. BLOOD. vol. 118, 112-112.
Ramsay AG, Clear AJ, Davenport A, Fatah R, Gribben JG (2011). Chronic Lymphocytic Leukemia Cells Co-Opt CD200,.CD270, CD274 and CD276 to Induce Impaired Actin Polarization At the T Cell Immune Synapse. BLOOD. vol. 118, 364-365.
Taussig DC, Gribben JG (2011). Continuous CD4+ T Cell Lines Derived From the Classical Hodgkin Lymphoma Microenvironment: A Challenge to the Assumption of Anergy. BLOOD. vol. 118, 1556-1557.
Coutinho R, Clear AJ, Owen DA, Greaves P, Hallam SL, Wilson A, Matthews J, Calaminici M et al. (2011). Exploring the Immune Microenvironment of Diffuse Large B Cell Lymphoma in a Tissue Microarray: Predicting Survival with a Score That Incorporates Macrophages, Cytotoxic and Regulatory T Cells. BLOOD. vol. 118, 434-435.
Montoto S, Shaw K, Okosun J, Gandhi S, Fields P, Wilson A, Shanyinde M, Cwynarski K et al. (2011). HIV Status Does Not Impact on Outcome in Patients with Hodgkin Lymphoma Treated with ABVD Chemotherapy in the HAART Era. BLOOD. vol. 118, 1557-1557.
Riches JC, Sangaralingam A, Kiaii S, Chaplin T, Cekdemir D, Iqbal S, Ramsay AG, Gribben JG (2011). Impact of Lenalidomide on Gene Expression Profiles of Malignant and Immune Cells in Patients with Chronic Lymphocytic Leukemia. BLOOD. vol. 118, 446-446.
Kiaii S, Clear AJ, Sangaralingam A, Gribben JG (2011). Impact of Tumor Infiltrating T Cells in Patients with Follicular Lymphoma At Diagnosis. BLOOD. vol. 118, 349-349.
Xing D, Ramsay AG, Robinson S, Bollard CM, Shah N, Champlin R, Gribben JG, Shpall EJ (2011). Lenalidomide Treatment Enhances Immunological Synapse Formation of Cord Blood Natural Killer Cells with B Cells Derived From Chronic Lymphocytic Leukemia. BLOOD. vol. 118, 783-783.
Hallam SL, Candido J, Coutinho R, Maniati E, Thompson RG, van Rooijen N, Hagemann T, Gribben JG (2011). Manipulating Tumor Associated Macrophages (TAM) in a Mouse Model of B-Cell Non-Hodgkin Lymphoma (NHL). BLOOD. vol. 118, 720-720.
El-Najjar I, Matthews J, Gribben J, Montoto S (2011). Neither the FLIPI Nor the FLIPI2 Accurately Segregates Low- Risk From Intermediate- Risk Follicular Lymphoma Patients in Terms of Progression-Free Survival. BLOOD. vol. 118, 1144-1144.
Iyengar S, Clear AJ, Owen A, Maharaj L, Matthews J, Calaminici M, Auer R, Ghazaly E et al. (2011). PI3K Inhibition with GDC-0941 Has Greater Efficacy Compared to p110 delta-Selective Inhibition with CAL-101 in Mantle Cell Lymphoma and May Be Particularly Advantageous in Multiply Relapsed Patients. BLOOD. vol. 118, 719-719.
Greaves P, Clear AJ, Owen A, Wilson A, Matthews J, Calaminici M, Gribben JG (2011). The PD1/PD-L1 Axis in the Classical Hodgkin Lymphoma Microenvironment: PD-1 Is Rarely Expressed but Identifies Patients with High-Risk Disease. BLOOD. vol. 118, 678-678.
El-Najjar I, Boumendil A, Luan JJ, Thieblemont C, Blaise D, Thomson K, Le Gouill S, Lissandre S et al. (2011). The Role of Total Body Irradiation (TBI) in the High-Dose Regimen of Patients with Follicular Lymphoma (FL) Treated with Autologous Stem Cell Transplant (ASCT) in the Rituximab Era. A Retrospective Study of the EBMT Lymphoma Working Party. BLOOD. vol. 118, 234-235.
Ramsay AG, Gribben JG(2011). The kiss of death in FL. Blood vol. 118, (20) 5365-5366.
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Riches JC, Ramsay AG, Gribben JG(2011). Chronic lymphocytic leukemia: an update on biology and treatment. Curr Oncol Rep vol. 13, (5) 379-385.
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Farren TW, Giustiniani J, Liu F-T, Tsitsikas DA, Macey MG, Cavenagh JD, Oakervee HE, Taussig D et al.(2011). Differential and tumor-specific expression of CD160 in B-cell malignancies. Blood vol. 118, (8) 2174-2183.
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Perrot A, Pionneau C, Nadaud S, Davi F, Leblond V, Jacob F, Merle-Beral H, Herbrecht R et al.(2011). A unique proteomic profile on surface IgM ligation in unmutated chronic lymphocytic leukemia. BLOOD vol. 118, (4) E1-E15.
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Gribben JG(2011). Are Prognostic Factors in CLL Overrated? THE MOUGALIAN/O'BRIEN ARTICLE REVIEWED. ONCOLOGY-NY vol. 25, (8) 703-706.
Gribben JG(2011). Are prognostic factors in CLL overrated?. Oncology (Williston Park) vol. 25, (8) 703-706.
Montserrat E, Gribben JG(2011). Autografting CLL: the game is over!. Blood vol. 117, (23) 6057-6058.
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Kiaii S, Clear AJ, Davis D, Ramsay AG, Sangaralingam A, Gribben JG (2011). DEFECTS AND ABNORMALITIES IN INFILTRATING T CELLS IN PATIENTS WITH FOLLICULAR LYMPHOMA AT DIAGNOSIS. ANNALS OF ONCOLOGY. vol. 22, 84-84.
Gribben J (2011). NEW EVIDENCE FOR MECHANISM OF ACTION OF IMIDS (R) IN LYMPHOMAS, FOCUS ON MCL. ANNALS OF ONCOLOGY. vol. 22, 254-255.
Hillmen P, Gribben JG, Follows GA, Milligan D, Sayala HA, Moreton P, Oscier DG, Dearden CE et al. (2011). RITUXIMAB PLUS CHLORAMBUCIL (R-CHLORAMBUCIL) AS FIRST-LINE TREATMENT FOR CHRONIC LYMPHOCYTIC LEUKAEMIA (CLL): FINAL ANALYSIS OF AN OPEN-LABEL PHASE II STUDY. ANNALS OF ONCOLOGY. vol. 22, 123-123.
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Montoto S, Matthews J, Anderson D, Lister A, Gribben J (2011). THE NUMBER OF PREVIOUS TREATMENT LINES HAS NO IMPACT ON THE OUTCOME AFTER HIGH-DOSE THERAPY WITH AUTOLOGOUS STEM CELL RESCUE WITH BEAM FOR RELAPSED FOLLICULAR LYMPHOMA. ANNALS OF ONCOLOGY. vol. 22, 115-115.
Greaves P, Clear A, Owen A, Matthews J, Macdougall F, Wilson A, Lister A, Calaminici M et al. (2011). TOTAL NUMBER OF B CELLS, BUT NOT T CELLS AT DIAGNOSIS IN THE CLASSICAL HODGKIN LYMPHOMA MICROENVIRONMENT IS PREDICTIVE OF SURVIVAL. ANNALS OF ONCOLOGY. vol. 22, 153-153.
Montoto S, Matthews J, Anderson D, Lister TA, Gribben JG(2011). Outcome after high-dose therapy with autologous stem cell rescue with BEAM for relapsed follicular lymphoma. J Clin Oncol vol. 29, (15_suppl)
Woyach JA, Ruppert AS, Heerema NA, Peterson BL, Gribben JG, Morrison VA, Rai KR, Larson RA et al.(2011). Chemoimmunotherapy with fludarabine and rituximab produces extended overall survival and progression-free survival in chronic lymphocytic leukemia: long-term follow-up of CALGB study 9712. J Clin Oncol vol. 29, (10) 1349-1355.
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El-Najjar I, Szyszko T, Matthews J, Gribben J, Avril N, Montoto S (2011). FDG-PET/CT staging in follicular lymphoma: effect on FLIPI score. BRITISH JOURNAL OF HAEMATOLOGY. vol. 153, 48-48.
Hillmen P, Gribben JG, Follows GA, Milligan D, Sayala HA, Moreton P, Oscier DG, Dearden CE et al. (2011). Final response assessment of the CLL208 trial: an open-label phase II study to investigate the safety and efficacy of rituximab plus chlorambucil in previously untreated patients with CD20-positive B-cell chronic lymphocytic leukaemia (CLL). BRITISH JOURNAL OF HAEMATOLOGY. vol. 153, 21-21.
Johnson R, Greaves P, Powell M, Vinnicombe S, Wilson A, Sarker S, Gribben J, Lister A (2011). Survey of breast screening in long-term survivors treated with supra-diaphragmatic irradiation for lymphoma. BRITISH JOURNAL OF HAEMATOLOGY. vol. 153, 47-47.
Wrench D, Leighton P, Skibola CF, Conde L, Cazier J-B, Matthews J, Iqbal S, Carlotti E et al.(2011). SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma. Blood vol. 117, (11) 3147-3150.
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Greaves PJ, Gribben JG(2011). Demonstration of durable graft versus lymphoma effects in Hodgkin's lymphoma. J Clin Oncol vol. 29, (8) 952-953.
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Gribben JG, O'Brien S(2011). Update on therapy of chronic lymphocytic leukemia. J Clin Oncol vol. 29, (5) 544-550.
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Wierda WG, Kipps TJ, Keating MJ, Brown JR, Gribben JG, Browning M, Rassenti LZ, Greaves AW et al.(2011). Self-Administered, Subcutaneous Alemtuzumab to Treat Residual Disease in Patients With Chronic Lymphocytic Leukemia. CANCER-AM CANCER SOC vol. 117, (1) 116-124.
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Gribben JG, Hosing C, Maloney DG(2011). Stem cell transplantation for indolent lymphoma and chronic lymphocytic leukemia. Biol Blood Marrow Transplant vol. 17, (1 Suppl) S63-S70.
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Riches JC, Davies J, Iqbal S, Fatah R, Agrawal S, Ramsay AG, Gribben JG (2011). T-cells from Patients With CLL Exhibit Phenotypic and Transcription Factor Profiles Of Exhaustion Independent of CMV Serostatus. Blood. vol. 118, 1780-1783.
Riches JC, Ramsay AG, Gribben JG(2010). T-cell function in chronic lymphocytic leukaemia. Semin Cancer Biol vol. 20, (6) 431-438.
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Tsitsikas DA, Sibony DW, Oakervee HE, Agrawal SG, Smith M, Taussig DC, de Vos J, Stewart E et al. (2010). A Phase II Trial of Sequential Treatment with Cytoreductive Therapy and Reduced Intensity Conditioning Allogeneic Stem Cell Transplantation for Relapsed/Refractory Acute Myeloid Leukaemia, High Risk MDS and Other High Risk Myeoid Malignancies An Interim Report. BLOOD. vol. 116, 1430-1430.
Tsitsikas DA, Warcel-Sibony D, Oakervee HE, Agrawal SG, Smith M, Taussig DC, de Vos J, Stewart E et al. (2010). A Phase II Trial of Sequential Treatment with Cytoreductive Therapy and Reduced Intensity Conditioning Allogeneic Stem Cell Transplantation for Relapsed/Refractory Acute Myeloid Leukaemia, High-Risk MDS and Other High Risk Myeoid Malignancies: An Interim Report. BLOOD. vol. 116, 1430-1430.
Greaves P, Wilson A, Matthews J, Brown DLP, Montoto S, Gribben JG, Lister A (2010). A Single-Centre Analysis by Intention to Treat with High Dose Chemotherapy and Autologous Stem Cell Rescue Following Second-Line Treatment In Patients with Hodgkin Lymphoma. BLOOD. vol. 116, 989-990.
Greaves P, Clear AJ, Owen DA, Macdougall F, Wilson A, Lister A, Calaminici M, Gribben JG (2010). An Immunohistochemical Score Based On CD68 and FOXP3 Expression In the Tumour Microenvironment at Diagnosis Defines Prognostic Groups In Both Early and Advanced Stage Classical Hodgkin Lymphoma. BLOOD. vol. 116, 330-330.
Liu F, Jia L, Farren T, Gribben JG, Agrawal S (2010). Autocrine IL6/STAT3 Signaling Enhances Survival of Chronic Lymphocytic Leukaemia Cells. BLOOD. vol. 116, 1481-1481.
Ramsay AG, Evans R, Svensson L, Kiati S, Hogg N, Gribben JG (2010). Defective LFA 1 Mediated T Cell Motility In Chronic Lymphocytic Leukemia Is Mediated by Defects In the Rho GTPase Signaling Pathway. BLOOD. vol. 116, 403-403.
Ramsay AG, Evans R, Svensson L, Kiaii S, Hogg N, Gribben JG (2010). Defective LFA-1 Mediated T Cell Motility In Chronic Lymphocytic Leukemia Is Mediated by Defects In the Rho GTPase Signaling Pathway. BLOOD. vol. 116, 403-403.
Kiaii S, Clear AJ, Ramsay AG, Sangaralingam A, Gribben JG (2010). Differential Gene Expression Profile Identifies Defects and Abnormalities In Infiltrating T Cells In Patients With Follicular Lymphoma at Diagnosis. BLOOD. Conference: 52nd Annual Meeting of the American-Society-of-Hematology (ASH) (Orlando, FL) from: 04/12/2010 to: 07/12/2010, vol. 116, 66-67.
Kiaii S, Clear AJ, Ramsay AG, Sangaralingam A, Gribben JG (2010). Differential Gene Expression Profile Identifies Defects and Abnormalities In Infiltrating T Cells In Patients with Follicular Lymphoma at Diagnosis. BLOOD. vol. 116, 66-67.
Wendtner C, Hillmen P, Mahadevan D, Stilgenbauer S, Uharek L, Coutre S, Frankturt O, Bloor A et al. (2010). Final Results of the Phase I Study of Lenalidomide In Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL 001 Study). BLOOD. vol. 116, 591-592.
Wendtner C, Hillmen P, Mahadevan D, Stilgenbauer S, Uharek L, Coutre S, Frankfurt O, Bloor A et al. (2010). Final Results of the Phase I Study of Lenalidomide In Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL-001 Study). BLOOD. vol. 116, 591-592.
Ramsay AG, Clear AJ, Davenport A, Fatah R, Gribben JG (2010). Functional Screening Studies Identify Combinational Activity of PD L1 and CD200 In Mediating Dysfunctional T Cell Immunological Synapse Formation In Chronic Lymphocytic Leukemia. BLOOD. Conference: 52nd Annual Meeting of the American-Society-of-Hematology (ASH) (Orlando, FL) from: 04/12/2010 to: 07/12/2010, vol. 116, 306-307.
Ramsay AG, Clear AJ, Davenport A, Fatah R, Gribben JG (2010). Functional Screening Studies Identify Combinational Activity of PD-L1 and CD200 In Mediating Dysfunctional T Cell Immunological Synapse Formation In Chronic Lymphocytic Leukemia. BLOOD. vol. 116, 306-307.
Smith MR, Neuberg D, Flinn IW, Grever MR, Bennett JM, Dewald G, Paietta EM, Litzow MR et al. (2010). Increased Incidence of Therapy Related Myeloid Neoplasia (t MN) After Initial Therapy for CLL with Fludarabine Cyclophosphamide (FC) Vs Fludarabine (F) Long Term Follow up of US Intergroup Study E2997. BLOOD. vol. 116, 408-409.
Smith MR, Neuberg D, Flinn IW, Grever MR, Bennett JM, Dewald G, Paietta EM, Litzow MR et al. (2010). Increased Incidence of Therapy Related Myeloid Neoplasia (t-MN) After Initial Therapy for CLL with Fludarabine-Cyclophosphamide (FC) Vs Fludarabine (F): Long-Term Follow-up of US Intergroup Study E2997. BLOOD. vol. 116, 408-409.
Butler T, Gribben JG, Hodgson A (2010). Physician Scientists In Hematology: Hematologists' Experiences of Research and Recruitment to Academia - A Mixed Methods, Qualitative Approach. BLOOD. vol. 116, 1063-1064.
Jia L, Gopinathan G, Sukumar JT, Gribben JG (2010). Potentiation of Bortezomib Induced Killing of Lymphoma Cells by Inhibition of Autophagy and Prevention of I kappa B alpha Degradation. BLOOD. vol. 116, 57-57.
Jia L, Gopinathan G, Sukumar JT, Gribben JG (2010). Potentiation of Bortezomib-Induced Killing of Lymphoma Cells by Inhibition of Autophagy and Prevention of I-kappa B alpha Degradation. BLOOD. vol. 116, 57-57.
Greaves P, Montoto S, Matthews J, Wilson A, Brown DLP, Lillington D, Gribben JG, Lister A (2010). Prospective Use of a Triple FISH Probe to Predict sMDS/AML Following High Dose Therapy with Autologous Stem Cell Rescue for Lymphoma. BLOOD. vol. 116, 1420-1420.
Hillmen P, Gribben JG, Follows GA, Milligan D, Sayala HA, Moreton P, Oscier DG, Deanden CE et al. (2010). Rituximab Plus Chlorambucil In Patients with CD20-Positive B Cell Chronic Lymphocytic Leukemia (CLL) Final Response Analysis of An Open Label Phase H Study. BLOOD. Conference: 52nd Annual Meeting of the American-Society-of-Hematology (ASH) (Orlando, FL) from: 04/12/2010 to: 07/12/2010, vol. 116, 307-307.
Hillmen P, Gribben JG, Follows GA, Milligan D, Sayala HA, Moreton P, Oscier DG, Dearden CE et al. (2010). Rituximab Plus Chlorambucil In Patients with CD20-Positive B-Cell Chronic Lymphocytic Leukemia (CLL): Final Response Analysis of An Open-Label Phase II Study. BLOOD. vol. 116, 307-307.
Wrench D, Sangaralingam A, Tayyib H, Kang MK, Riain C, Gupta M, Carlotti E, Bodor C et al. (2010). TNERSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenviroment In Transformed Follicular Lymphoma. BLOOD. vol. 116, 349-349.
Wrench D, Sangaralingam A, Tayyib H, Kang MK, Riain C, Gupta M, Carlotti E, Bodor C et al. (2010). TNFRSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenvironment In Transformed Follicular Lymphoma. BLOOD. vol. 116, 349-349.
Xing DX, Decker W, Li SF, Robinson S, Shah N, Yang H, Champlin RE, Parmar S et al. (2010). Targeting Chronic Lymphocytic Leukemia with Cord Blood NK Cells In NSG Model. BLOOD. vol. 116, 1018-1019.
Buchner M, Brantner P, Stickel N, Prinz G, Burger M, Bar C, Dierks C, Pfeifer D et al.(2010). The microenvironment differentially impairs passive and active immunotherapy in chronic lymphocytic leukaemia-CXCR4 antagonists as potential adjuvants for monoclonal antibodies. BRIT J HAEMATOL vol. 151, (2) 167-178.
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Gribben JG(2010). Chronic lymphocytic leukemia: planning for an aging population. Expert Rev Anticancer Ther vol. 10, (9) 1389-1394.
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Xing D, Ramsay AG, Gribben JG, Decker WK, Burks JK, Munsell M, Li S, Robinson SN et al.(2010). Cord blood natural killer cells exhibit impaired lytic immunological synapse formation that is reversed with IL-2 exvivo expansion. J Immunother vol. 33, (7) 684-696.
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Gribben JG(2010). Implications of the tumor microenvironment on survival and disease response in follicular lymphoma. CURR OPIN ONCOL vol. 22, (5) 424-430.
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Czuczman M, Straus D, Gribben J, Bredenfeld H, Friedberg J, Bollard C (2010). Management options, survivorship, and emerging treatment strategies for follicular and Hodgkin lymphomas. LEUKEMIA & LYMPHOMA. vol. 51, 41-49.
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Gribben J, Rosenwald A, Gascoyne R, Lenz G(2010). Targeting the microenvironment. Leuk Lymphoma vol. 51 Suppl 1, 34-40.
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Clear AJ, Lee AM, Calaminici M, Ramsay AG, Morris KJ, Hallam S, Kelly G, Macdougall F et al.(2010). Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment. Blood vol. 115, (24) 5053-5056.
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Taussig D, Miraki-Moud F, Lister A, Bonnet D, Gribben J (2010). BONE MARROW FAILURE IN ACUTE MYELOID LEUKEMIA IS INDUCED BY A BLOCK IN DIFFERENTIATION OF NORMAL HEMATOPOIETIC STEM CELLS. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 95, 13-13.
O' Riain C, Smith P, Clear A, Wrench D, Gupta M, Bodor C, Matolcsy A, Calaminici M et al. (2010). EZH2 MUTATION IN FOLLICULAR LYMPHOMA. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 95, 167-167.
Wrench J, Skibola C, Matthews J, Cazier JB, Iqbal S, Carlotti E, Calaminici M, Davies A et al. (2010). SNP RS6457327 ON CHROMOSOME 6P PREDICTS TRANSFORMATION OF FOLLICULAR LYMPHOMA. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 95, 170-171.
Sziosarek PW, Delage B, O'Riain C, Hatzimichael E, Crook T, Calaminici M, Gribben JG, Lemoine N et al.(2010). Effect of inactivation of argininosuccinate synthetase on sensitivity of lymphomas to caspase-dependent apoptosis following treatment with arginine deiminase. JOURNAL OF CLINICAL ONCOLOGY vol. 28, (15)
Streetly MJ, Maharaj L, Joel S, Schey SA, Gribben JG, Cotter FE(2010). GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death. BLOOD vol. 115, (19) 3939-3948.
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Hillmen P, Gribben JG, Follows GA, Milligan DW, Sayala HA, Moreton P, Oscier D, Dearden CE et al. (2010). An open-label phase II study to investigate the safety and efficacy of rituximab plus chlorambucil in previously untreated patients with CD20-positive B-cell chronic lymphocytic leukaemia (CLL): On behalf of the NCRI CLL sub-group. BRITISH JOURNAL OF HAEMATOLOGY. vol. 149, 2-2.
Butler T, Gribben JG(2010). Biologic and clinical significance of molecular profiling in Chronic Lymphocytic Leukemia. Blood Rev vol. 24, (3) 135-141.
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Auer RL, MacDougall F, Oakervee HE, Cavenagh JC, Gribben JG, Lister TA (2010). Fludarabine/cyclophosphamide non-myeloablative allogeneic stem cell transplantation for lymphoid malignancies. BRITISH JOURNAL OF HAEMATOLOGY. vol. 149, 70-70.
Liu F-T, Giustiniani J, Farren T, Jia L, Bensussan A, Gribben JG, Agrawal SG(2010). CD160 signaling mediates PI3K-dependent survival and growth signals in chronic lymphocytic leukemia. Blood vol. 115, (15) 3079-3088.
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Ramsay AG, Gribben JG(2010). The 3 Rs in CLL immune dysfunction. Blood vol. 115, (13) 2563-2564.
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Taussig DC, Vargaftig J, Miraki-Moud F, Griessinger E, Sharrock K, Luke T, Lillington D, Oakervee H et al.(2010). Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction. Blood vol. 115, (10) 1976-1984.
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Nagler A, Labopin M, Shimoni A, Mufti G, Cornelissen JJ, Blaise D, Janssen JJWM, Milpied N et al. (2010). Mobilized peripheral blood stem cells compared with bone marrow for related reduced-intensity transplantation in acute myeloid leukaemia in complete remission: a retrospective analysis from the ALWP of EBMT. BONE MARROW TRANSPLANTATION. vol. 45, S21-S22.
Hallam S, Gribben JG(2010). Stem cell transplantation in chronic lymphocytic leukaemia - steering a safe course over shifting sands. Best Pract Res Clin Haematol vol. 23, (1) 109-119.
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Gribben JG(2010). How I treat CLL up front. Blood vol. 115, (2) 187-197.
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Hillmen P, Gribben JG, Follows GA, Milligan DW, Sayala HA, Moreton P, Oscier D, Dearden CE et al. (2009). An Open-Label Phase II Study to Investigate the Safety and Efficacy of Rituximab Plus Chlorambucil in Previously Untreated Patients with CD20-Positive B-Cell Chronic Lymphocytic Leukaemia (CLL). BLOOD. vol. 114, 1331-1332.
Mohty M, Labopin M, Janssen JJWM, Mufti GJ, Cornelissen JJ, Milpied NJ, Sengeloev H, Blaise D et al. (2009). Comparison of Low Dose Total Body Irradiation (TBI)-Based Reduced Intensity Conditioning (RIC) Vs. Chemotherapy-Based RIC Prior to Allogeneic Stem Cell Transplantation (allo-SCT) From An HLA Identical Sibling Donor for Acute Myeloid Leukemia (AML) in First Complete Remission (CR1): a Retrospective Analysis of 1200 Patients From the Acute Leukemia Working Party of EBMT. BLOOD. vol. 114, 489-489.
Xing DX, Ramsay AG, Decker W, Li SF, Robinson S, Yang H, Shah N, Hosing C et al. (2009). Dramatic Reduction of Chronic Lymphocytic Leukemia (CLL) Cells Following Adoptive Transfer of Cord Blood (CB) Natural Killer (NK) Cells Using CB-Engrafted NOD-SCID IL2R gamma(null) (NSG) Mice as a Model. BLOOD. vol. 114, 936-936.
Xing DX, Ramsay AG, Decker W, Li SF, Robinson S, Yang H, Bollard CM, Gribben JG et al. (2009). Ex Vivo IL-2 Expansion of CB-NK Cells Promotes Synergistic LFA-1 and CD2 Engagement at the NK Cell Lytic Immune Synapse; Implications for Adoptive CB-NK Cell Therapy in Acute Myeloid Leukemia. BLOOD. vol. 114, 1180-1181.
Xing DX, Ramsay AG, Decker W, Li SF, Robinson S, Yang H, Gribben JG, Shpall EJ (2009). Impaired Natural Killer Cells Immune Synapse Formation in Acute Myeloid Leukemia. BLOOD. vol. 114, 1044-1044.
Woyach JA, Ruppert AS, Heerema NA, Peterson B, Gribben JG, Morrison VA, Rai KR, Larson RA et al. (2009). Treatment with Fludarabine and Rituximab Produces Extended Overall Survival (OS) and Progression-Free Survival (PFS) in Chronic Lymphocytic Leukemia (CLL) without Increased Risk of Second Malignancy: Long-Term Follow up of CALGB Study 9712. BLOOD. vol. 114, 226-226.
Ramsay AG, Clear AJ, Kelly G, Fatah R, Matthews J, Macdougall F, Lister TA, Lee AM et al.(2009). Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy. Blood vol. 114, (21) 4713-4720.
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Riches JC, Gribben JG(2009). Interesting times in the diagnosis and treatment of CLL. Oncology (Williston Park) vol. 23, (12) 1043-1046.
O'Brien S, Moore JO, Boyd TE, Larratt LM, Skotnicki AB, Koziner B, Chanan-Khan AA, Seymour JF et al.(2009). 5-year survival in patients with relapsed or refractory chronic lymphocytic leukemia in a randomized, phase III trial of fludarabine plus cyclophosphamide with or without oblimersen. J Clin Oncol vol. 27, (31) 5208-5212.
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Le Dieu R, Taussig DC, Ramsay AG, Mitter R, Miraki-Moud F, Fatah R, Lee AM, Lister TA et al.(2009). Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts. Blood vol. 114, (18) 3909-3916.
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Gribben JG(2009). One step back but 2 steps forward. Blood vol. 114, (16) 3359-3360.
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Carlotti E, Gribben JG(2009). Stem cell mimicry: key to transformation?. Blood vol. 114, (15) 3133-3134.
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O'Riain C, O'Shea DM, Yang Y, Le Dieu R, Gribben JG, Summers K, Yeboah-Afari J, Bhaw-Rosun L et al.(2009). Array-based DNA methylation profiling in follicular lymphoma. Leukemia vol. 23, (10) 1858-1866.
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Ramsay AG, Gribben JG(2009). Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug. HAEMATOL-HEMATOL J vol. 94, (9) 1198-1202.
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Tsitsikas DA, Oakervee H, Cavenagh JD, Gribben J, Agrawal SG, Mattes FM(2009). Treatment of respiratory syncytial virus infection in haemopoietic stem cell transplant recipients with aerosolized ribavirin and the humanized monoclonal antibody palivizumab: a single centre experience. Br J Haematol vol. 146, (5) 574-576.
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Le Dieu R, Taussig D, Lister TA, Gribben JG(2009). Negative immunomagnetic selection of T cells from peripheral blood of presentation AML specimens. J Immunol Methods vol. 348, (1-2) 95-100.
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Buchner M, Fuchs S, Prinz G, Pfeifer D, Bartholome K, Burger M, Chevalier N, Vallat L et al.(2009). Spleen Tyrosine Kinase Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia. CANCER RES vol. 69, (13) 5424-5432.
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Wendtner CM, Mahadevan D, Coutre S, Hillmen P, Stilgenbauer S, Frankfurt O, Bloor A, Bosch F et al. (2009). A PHASE I DOSE-ESCALATION OF LENALIDOMIDE IN PATIENTS WITH RELAPSED OR REFRACTORY CHRONIC LYMPHOCYTIC LEUKEMIA. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 94, 371-372.
Cotter F, Smith DA, Boyd TE, Richards DA, Alemany C, Loesch D, Salogub G, Tidmarsh GF et al. (2009). Single-agent activity of GCS-100, a first-in-class galectin-3 antagonist, in elderly patients with relapsed chronic lymphocytic leukemia. JOURNAL OF CLINICAL ONCOLOGY. vol. 27,
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Gorgun G, Ramsay AG, Holderried TAW, Zahrieh D, Le Dieu R, Liu F, Quackenbush J, Croce CM et al.(2009). E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction. Proc Natl Acad Sci U S A vol. 106, (15) 6250-6255.
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Gorgun G, Ramsay AG, Holderried TAW, Zahrieh D, Dieu RL, Liu F, Quackenbush J, Croce CM et al.(2009). Eμ- TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction. Proceedings of the National Academy of Sciences of the United States of America vol. 106, (15) 6250-6255.
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Carlotti E, Wrench D, Matthews J, Iqbal S, Davies A, Norton A, Hart J, Lai R et al.(2009). Transformation of follicular lymphoma to diffuse large B-cell lymphoma may occur by divergent evolution from a common progenitor cell or by direct evolution from the follicular lymphoma clone. Blood vol. 113, (15) 3553-3557.
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O'Shea D, O'Riain C, Gupta M, Waters R, Yang Y, Wrench D, Gribben J, Rosenwald A et al.(2009). Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation. Blood vol. 113, (10) 2298-2301.
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Messmer BT, Raphael BJ, Aerni SJ, Widhopf GF, Rassenti LZ, Gribben JG, Kay NE, Kipps TJ(2009). Computational identification of CDR3 sequence archetypes among immunoglobulin sequences in chronic lymphocytic leukemia. Leuk Res vol. 33, (3) 368-376.
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Gribben JG, Hallek M(2009). Rediscovering alemtuzumab: current and emerging therapeutic roles. Br J Haematol vol. 144, (6) 818-831.
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Tsitsikas DA, Oakervee H, Cavenagh J, Agrawal S, Gribben J, Mattes F (2009). Treatment of respiratory syncytial virus infection with nebulised ribavirin and the humanised monoclonal antibody palivizumab in eight haemopoietic stem cell transplant recipients. BONE MARROW TRANSPLANTATION. vol. 43, S252-S253.
Xing D, Ramsary AG, Gribben JG, Decker WK, Li S, Robinson SN, Yang H, David S et al. (2009). DEFECTIVE IMMUNE SYNAPSE FORMATION OF UMBILICAL CORD BLOOD-DERIVED NATURAL KILLER CELL S IS ABROGATED BY EX VIVO EXPANSION. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. vol. 15, 117-118.
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Decker WK, Li S, Xing D, Robinson SN, Yang H, Steiner D, Lapusbin R, Ramsay AG et al. (2009). GENERATION OF CLL-SPECIFIC CTL EFFECTORS FROM PARTIALLY HLA-MATCHED UMBILICAL CORD BLOOD GRAFTS USING CD154-TRANSDUCED CLL CELL S AS APCS. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. vol. 15, 123-123.
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Elter T, Vehreschild J, Gribben J, Cornely O, Engert A, Hallek M(2009). Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab. ANN HEMATOL vol. 88, (2) 121-132.
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Wrench D, Waters R, Carlotti E, Iqbal S, Matthews J, Calaminici M, Gribben J, Lister TA et al.(2009). Clinical relevance of MDM2 SNP 309 and TP53 Arg72Pro in follicular lymphoma. HAEMATOL-HEMATOL J vol. 94, (1) 148-150.
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Gribben JG (2009). Stem cell transplantation in chronic lymphocytic leukemia. Biol Blood Marrow Transplant. vol. 15, 53-58.
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Hallam S, Gribben JG(2009). Transplantation in chronic lymphocytic leukemia: timing and expectations. Clin Lymphoma Myeloma vol. 9 Suppl 3, S186-S193.
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Brown JR, Rassenti L, Neuberg D, Greaves A, Byrd JC, Grever MR, Gribben JG, Kay NE et al. (2008). Characteristics of Familial CLL Evaluated in the CLL Research Consortium Cohort. BLOOD. vol. 112, 1071-1072.
Ramsay AG, Clear AJ, Fatah R, Gribben JG (2008). Co-Treatment with Panobinostat Enhances Bortezomib-Induced Unfolded Protein Response, Endoplasmic Reticulum Stress and Apoptosis of Human Mantle Cell Lymphoma Cells. BLOOD. vol. 112, 327-327.
Brown JR, Stevenson K, Kim HT, Armand P, Cutler C, Fisher DC, Ho V, Koreth J et al. (2008). Comparative Outcome of Myeloablative and Reduced Intensity Allogeneic Stem Cell Transplantation for Chronic Lymphocytic Leukemia. BLOOD. vol. 112, 357-358.
Ramsay AG, Xing DX, Decker WK, Burks JK, Wierda WG, Gribben JG, Shpall EJ (2008). Compared to Adult Peripheral Blood T Cells, Cord Blood T Cells Show Enhanced Immunological Recognition of Chronic Lymphocytic Leukemia Tumor Cells. BLOOD. vol. 112, 813-813.
Ramsay AG, Svensson L, Hogg N, Gribben JG (2008). Defective T Cell Migration in Chronic Lymphocytic Leukemia Is Repaired by Lenalidomide. BLOOD. vol. 112, 1069-1069.
Le Dieu R, Ramsay AG, Taussig D, Mitter R, Gribben JG (2008). Differential Gene Expression Profile Identifies the Nature of T Cell Defects in AML Patients at Diagnosis. BLOOD. vol. 112, 433-433.
Agrawal SG, Liu FT, Giustiniani J, Jia L, Gribben JG, Bensussan A (2008). Dual Action of CD160 on CLL Cells: Giving Life to Prepare for Death!. BLOOD. vol. 112, 726-726.
Xing DX, Ramsay AG, Gribben JG, Decker WK, Burt JK, Li SF, Simon SN, Yang H et al. (2008). Ex Vivo Expansion of Cord Blood Natural Killer Cells Overcomes Impaired Immune Synapse Formation and Effector Function in Acute Myeloid Leukemia. BLOOD. vol. 112, 999-999.
Clear AJ, Lee AM, Morris KJ, Calaminici M, Macdougall F, Goff LK, Lister TA, Gribben JG (2008). Extended Focal Imaging Reveals An Improved Gauge of Angiogenic Activity and Highlights the Role of Angiogenesis in Survival and Time to Transformation in Follicular Lymphoma. BLOOD. vol. 112, 975-975.
Ramsay AG, Clear AJ, Fatah R, Gribben JG (2008). Lenalidomide Repairs Suppressed T Cell Immunological Synapse Formation in Follicular Lymphoma. Conference: 50th Annual Meeting of the American- Society-of-Hematology (San Francisco, CA) from: 06/12/2008 to: 09/12/2008,
Wendtner CM, Mahadevan D, Stilgenbauer S, Frankfurt O, Bloor A, Bosch F, Uharek L, Furman RR et al. (2008). Preliminary Results of a Phase 1/2, Multi-Center, Open-Label Study (CLL-001) Investigating a Stepwise Dose-Escalation Schedule of Lenalidomide in Relapsed or Refractory Chronic-Lymphocytic-Leukemia. BLOOD. vol. 112, 732-732.
Buchner M, Fuchs S, Prinz G, Pfeifer D, Bartholomee K, Chevalier N, Vallat L, Timmer J et al. (2008). Spleen Tyrosine Kinase (SYK) Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia. BLOOD. vol. 112, 203-203.
Liu F-T, Agrawal SG, Movasaghi Z, Wyatt PB, Rehman IU, Gribben JG, Newland AC, Jia L(2008). Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib. Blood vol. 112, (9) 3835-3846.
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Gribben JG(2008). Role of allogeneic hematopoietic stem-cell transplantation in chronic lymphocytic leukemia. J Clin Oncol vol. 26, (30) 4864-4865.
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O'Shea D, O'Riain C, Taylor C, Waters R, Carlotti E, Macdougall F, Gribben J, Rosenwald A et al.(2008). The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival. Blood vol. 112, (8) 3126-3129.
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Wrench D, Gribben JG(2008). Stem cell transplantation for non-Hodgkin's lymphoma. Hematol Oncol Clin North Am vol. 22, (5) 1051-xi.
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Davies JK, Gribben JG, Brennan LL, Yuk D, Nadler LM, Guinan EC(2008). Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies. Blood vol. 112, (6) 2232-2241.
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Ramsay AG, Gribben JG(2008). Vaccine therapy and chronic lymphocytic leukaemia. Best Pract Res Clin Haematol vol. 21, (3) 421-436.
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Taussig DC, Miraki-Moud F, Anjos-Afonso F, Pearce DJ, Allen K, Ridler C, Lillington D, Oakervee H et al.(2008). Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells. Blood vol. 112, (3) 568-575.
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Proto-Siqueira R, Panepucci RA, Careta FP, Lee A, Clear A, Morris K, Owen C, Rizzatti EG et al.(2008). SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL. BLOOD vol. 112, (2) 394-397.
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Ramsay AG, Johnson AJ, Lee AM, Gorgün G, Le Dieu R, Blum W, Byrd JC, Gribben JG(2008). Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug. J Clin Invest vol. 118, (7) 2427-2437.
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de Jong D, Lee AM, Hauptmann M, Heisterkamp S, Calaminici M, Gribben JG, Kerst M, Lister TA (2008). Changes in follicular lymphoma are related to time to transformation to diffuse large B-cell lymphoma. ANNALS OF ONCOLOGY. vol. 19, 111-111.
Cotter FE, Gribben J, Streetly M, Auer R, Smith D, Alemany C, Loesch D, Boyd TE et al. (2008). Clinical caspase activation in CLL by GCS-100, a novel carbohydrate, in a phase 2 study. ANNALS OF ONCOLOGY. vol. 19, 90-90.
Lee AM, Clear AJ, Morris KJ, Calaminici MR, Matthews J, Gribben JG, Lister TA (2008). Examination of changes in tumour microenvironment of follicular lymphoma using serial sample tissue microarrays. ANNALS OF ONCOLOGY. vol. 19, 179-179.
Wrench D, Waters R, Matthews J, Calaminici M, Carlotti E, Iqbal S, Gribben J, Lister A et al. (2008). MDM2 309 and TP53 ARG72PRO SNP genotypes do not predict clinical outcome of follicular lymphoma. ANNALS OF ONCOLOGY. vol. 19, 178-178.
O'Riain C, O'Shea D, Yang Y, Gribben J, Afari J, Mein CA, Crook T, Smith P et al. (2008). Methylation profiling in 158 cases of previously untreated follicular lymphoma (FL). ANNALS OF ONCOLOGY. vol. 19, 101-101.
Gribben JG(2008). New agents in chronic lymphocytic leukemia. Clin Adv Hematol Oncol vol. 6, (6) 409-468.
O'Shea D, O'Riain C, MacDougall F, Gribben J, Young BD, Rosenwald A, Rimsza L, Roberts R et al. (2008). SNP array genotyping in 182 diagnostic follicular lymphoma cases identifies sites of AUPD associated with overall survival and risk of transformation. ANNALS OF ONCOLOGY. vol. 19, 111-111.
Lee AM, Clear AJ, Morris KJ, Calaminici MR, Matthews J, Gribben JG, Lister TA (2008). The impact of tumour microenvironment in diagnostic follicular lymphoma samples using tissue microarrays. ANNALS OF ONCOLOGY. vol. 19, 126-126.
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Ghia EM, Jain S, Widhopf GF, Rassenti LZ, Keating MJ, Wierda WG, Gribben JG, Brown JR et al.(2008). Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection. BLOOD vol. 111, (10) 5101-5108.
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Gilleece MH, Pearce R, Linch DC, Wilson M, Towlson K, Mackinnon S, Potter M, Kazmi M et al.(2008). The outcome of haemopoietic stem cell transplantation in the treatment of lymphoplasmacytic lymphoma in the UK: a British Society Bone Marrow Transplantation study. Hematology vol. 13, (2) 119-127.
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Widhopf GF, Goldberg CJ, Toy TL, Rassenti LZ, Wierda WG, Byrd JC, Keating MJ, Gribben JG et al.(2008). Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3. BLOOD vol. 111, (6) 3137-3144.
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Liu F-T, Agrawal SG, Gribben JG, Ye H, Du M-Q, Newland AC, Jia L(2008). Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL. Blood vol. 111, (5) 2797-2805.
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Agrawal SG, Liu FT, Wiseman C, Shirali S, Liu H, Lillington D, Du MQ, Syndercombe-Court D et al.(2008). Increased proteasomal degradation of Bax is a common feature of poor prognosis chronic lymphocytic leukemia. BLOOD vol. 111, (5) 2790-2796.
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Davies J, Gribben J, Brennan L, Nadler L, Guinan E (2008). ALLOANERGIZED HLA-MISMATCHED BONE MARROW TRANSPLANTATION - LOW INCIDENCE OF CLINICALLY SIGNIFICANT GVHD AND VIRAL INFECTION RESULTING IN LONG TERM DISEASE FREE SURVIVAL. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. Conference: Annual Meeting of the American-Society-for-Blood-and-Marrow-Transplantation (San Diego, CA) from: 13/02/2008 to: 17/02/2008, vol. 14, 16-17.
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Ramsay AG, Gorgun G, Holderried TAW, Zahrieh D, Liu FL, Quackenbush J, Croce CM, Gribben JG (2008). A Mouse Model for Immunotherapeutic Reversal of Leukemia-induced T Cell Dysfunction. Conference: 50th ASH Annual Meeting and Exposition (Moscone Center, San Francisco, CA) from: 06/12/2008 to: 09/12/2008,
Butler T, Gribben JG(2008). Biologic prognostic markers and their application in clinical trials and management of chronic lymphocytic leukaemia patients. Expert Opinion on Medical Diagnostics vol. 2, (1) 101-112.
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Le Dieu R, Gribben JG(2008). Chronic Lymphocytic Leukaemia. Hematopoietic Stem Cell Transplantation, Editors: Soiffer, RJ, Edition. 1, Springer
Gribben JG(2008). Chronic lymphocytic leukemia: an historical perspective. Hematology Am Soc Hematol Educ Program
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Gribben JG(2008). Molecular profiling in CLL. Hematology Am Soc Hematol Educ Program444-449.
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Buske C, Gisselbrecht C, Gribben J, Letai T, McLaughlin P, Wilson W (2008). Refining the treatment of follicular lymphoma. LEUKEMIA & LYMPHOMA. vol. 49, 18-26.
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Stevens JM, Syndercombe-Court D, Oakervee HE, McCloskey D, Jenner MJ, Gribben JG, Cavenagh JD(2007). Development of original donor cell leukemia after successful engraftment from a second donor. BLOOD vol. 110, (13) 4621-4622.
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Auer RL, Gribben J, Cotter FE(2007). Emerging therapy for chronic lymphocytic leukaemia. Br J Haematol vol. 139, (5) 635-644.
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Doffman SR, Griffiths LJ, Lim C, Vinnicombe S, Wilks M, Gribben JG, Griffiths MJ, Agrawal SG (2007). A novel non-invasive method of detecting galactomannan in suspected pulmonary aspergillosis. BLOOD. vol. 110, 33B-33B.
Clear AJ, Lee AM, Morris KJ, Calaminici M, Macdougall F, Proto-Siqueira R, Goff LK, Lister TA et al. (2007). Angiogenesis assessed in tissue microarrays of diagnostic follicular lymphoma correlates with outcome. BLOOD. vol. 110, 768A-768A.
Agrawal SG, Liu FT, Wiseman C, Shirali S, Liu H, Lillington D, Du MQ, Court DS et al. (2007). Bax degradation activity is a novel poor prognosis marker of chronic lymphocytic leukemia. BLOOD. vol. 110, 908A-908A.
Le Dieu R, Taussig D, MacDougal F, Lister A, Gribben JG (2007). CD3+/CD56+cells, but not natural killer T cells, are increased in peripheral blood of untreated patients with leukemia. BLOOD. vol. 110, 538A-538A.
Giustiniani J, Wiseman C, Farren T, Gribben JG, Agrawal SG (2007). CLL cell proliferation and IL-6 production are regulated by CD160-MHC class I interactions offering new therapeutic targets. BLOOD. vol. 110, 342A-342A.
Carlotti E, Wrench D, Iqbal S, O'Shea D, Davies A, Virappane P, Hart J, Lai R et al. (2007). Determining the mechanism of transformation of follicular lymphoma into diffuse large B cell lymphoma. BLOOD. vol. 110, 61A-61A.
Wiseman C, Giustiniani J, Mikkelsen L, Macey M, Goff L, Gribben J, Agrawal S (2007). High frequency of surface immunoglobulin IgG in B-Cell chronic lymphocytic leukaemia. BLOOD. vol. 110, 245B-245B.
Ramsay AG, Lee AM, Gribben JG (2007). Impaired actin polymerization results in defective immunological synapse formation in T cells in chronic lymphocytic leukemia. BLOOD. vol. 110, 106A-107A.
Proto-Siqueira R, Panepucci RA, Careta FP, Rizzatti EG, Lee A, Clear A, Morris K, Falcao RP et al. (2007). SAGE analysis demonstrates increased expression of TOSO contributing to Fas mediated resistance in CLL. BLOOD. vol. 110, 340A-340A.
Ghia LEM, Rassenti LZ, Widhopf GF, Silverman GJ, Neuberg DS, Keating MJ, Wierda WG, Gribben JG et al. (2007). Stereotypie IGHV3-21/IGLV3-21 antibodies expressed in high-risk chronic lymphocytic leukemia bind peptostreptococcus magnus protein. BLOOD. vol. 110, 227A-228A.
Vallat L, Pionneau C, Jacob F, Davi F, Leblond V, Gribben JG, Merle-Beral H (2007). Temporal proteomic analysis of CLL B cell response to antigen receptor stimulation. BLOOD. vol. 110, 344A-344A.
Gribben JG (2007). Do we need allogeneic transplantation in HL?. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL. vol. 92, 19-19.
Brown JR, Feng Y, Gribben JG, Neuberg D, Fisher DC, Mauch P, Nadler LM, Freedman AS(2007). Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission. Biol Blood Marrow Transplant vol. 13, (9) 1057-1065.
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Zhou J, Goldwasser MA, Li A, Dahlberg SE, Neuberg D, Wang H, Dalton V, McBride KD et al.(2007). Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL Consortium Protocol 95-01. Blood vol. 110, (5) 1607-1611.
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Gribben JG(2007). Stem-cell transplantation in chronic lympocytic leukaernia. BEST PRACT RES CL HA vol. 20, (3) 513-527.
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Rohatiner AZS, Nadler L, Davies AJ, Apostolidis J, Neuberg D, Matthews J, Gribben JG, Mauch PM et al. (2007). Myeloablative therapy with autologous bone marrow transplantation for follicular lymphoma at the time of second or subsequent remission: long-term follow-up. J Clin Oncol. vol. 25, 2554-2559.
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Gribben JG(2007). How I treat indolent lymphoma. BLOOD vol. 109, (11) 4617-4626.
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Vallat LD, Park Y, Li C, Gribben JG(2007). Temporal genetic program following B-cell receptor cross-linking: altered balance between proliferation and death in healthy and malignant B cells. Blood vol. 109, (9) 3989-3997.
10.1182/blood-2006-09-045377
Wallis LC, Streetly MJ, Auer R, Gribben J, Zhang D, Hankins WD, Zadeh SM, Cotter FE (2007). Dynamic assessment of apoptosis for in vitro design of bortezomib combination therapies for lymphoid malignancies. BRITISH JOURNAL OF HAEMATOLOGY. vol. 137, 63-63.
Grever MR, Lucas DM, Dewald GW, Neuberg DS, Reed JC, Kitada S, Flinn IW, Tallman MS et al.(2007). Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997. J Clin Oncol vol. 25, (7) 799-804.
10.1200/JCO.2006.08.3089
Le Dieu R, Gribben JG(2007). Transplantation in chronic lymphocytic leukemia. Curr Hematol Malig Rep vol. 2, (1) 56-63.
10.1007/s11899-007-0008-0
Zirlik KM, Zahrieh D, Neuberg D, Gribben JG(2006). Cytotoxic T cells generated against heteroclitic peptides kill primary tumor cells independent of the binding affinity of the native tumor antigen peptide. Blood vol. 108, (12) 3865-3870.
10.1182/blood-2006-04-014415
Wallis LC, Streetly MJ, Auer R, Gribben J, Zhang D, Hankins WD, Zadeh SM, Cotter FE (2006). Dynamic assessment of apoptosis for in vitro design of bortezomib combination therapies for lymphoid malignancies. BLOOD. vol. 108, 706A-706A.
Lee AM, Clear A, Calaminici M, Macdougall F, Goff L, Gribben JG (2006). Increased CD69 and decreased CD4 expressing cells in tissue microarray (TMA) in diagnostic lymph node biopsies are associated with poor outcome in CLL/SLL. BLOOD. vol. 108, 787A-787A.
Brown JR, Gribben JG, Feng Y, Neuberg D, Mauch P, Nadler LM, Freedman AS (2006). Long-term follow-up of autologous bone marrow transplantation for follicular lymphoma in first remission: Bone marrow involvement at harvest and PCR detectable disease after ex vivo purging predict relapse. BLOOD. vol. 108, 865A-865A.
Rassenti LZ, Neuberg DS, Huynh L, Wierda WG, Gribben JG, Brown JR, Flinn IW, Rai KR et al. (2006). Relative value of CD38 and ZAP-70 versus immunoglobutin mutation status in predicting early disease progression in chronic lymphocytic leukemia. BLOOD. vol. 108, 786A-787A.
Wierda WG, Kipps TJ, Keating MJ, Brown JR, Gribben JG, Browning ML, Rassenti L, Greaves A et al. (2006). Self-administered, subcutaneous (SQ) alemtuzumab to eliminate residual disease in patients (pts) with CLL. BLOOD. vol. 108, 804A-804A.
Zirlik K, Burger M, Brantner P, Prinz G, Buchner M, Gribben JG, Veelken H (2006). Stromal cells protect B-CLL cells from killing by antigen-specific cytotoxic T cells. BLOOD. vol. 108, 796A-797A.
Ghia EM, Rassenti LZ, Widhopf GF, Neuberg DS, Keating MJ, Wierda WG, Gribben JG, Brown JR et al. (2006). Study of VH3-21 in a large cohort of chronic lymphocytic leukemia patients reveals evidence for antigen selection and confirms its predictive value for early disease progression. BLOOD. vol. 108, 785A-785A.
Gilleece MH, Pearce R, Linen DC, Wilson M, Towlson K, Mackinnon S, Potter M, Kamzi M et al. (2006). Utilisation of stem cell transplantation for lymphoplasmacytic lymphoma in the UK. BLOOD. vol. 108, 844A-845A.
Lee AM, Clear AJ, Calaminici M, Davies AJ, Jordan S, MacDougall F, Matthews J, Norton AJ et al. (2006). Number of CD4+ cells and location of forkhead box protein P3-positive cells in diagnostic follicular lymphoma tissue microarrays correlates with outcome. J Clin Oncol. vol. 24, 5052-5059.
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Brown JR, Kim HT, Li S, Stephans K, Fisher DC, Cutler C, Ho V, Lee SJ et al.(2006). Predictors of improved progression-free survival after nonmyeloablative allogeneic stem cell transplantation for advanced chronic lymphocytic leukemia. Biol Blood Marrow Transplant vol. 12, (10) 1056-1064.
10.1016/j.bbmt.2006.06.004
Faderl S, Rai K, Gribben J, Byrd JC, Flinn IW, O'Brien S, Sheng SH, Esseltine DL et al.(2006). Phase II study of single-agent bortezomib for the treatment of patients with fludarabine-refractory B-cell chronic lymphocytic leukemia. CANCER vol. 107, (5) 916-924.
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Gribben JG(2006). Of mice and men... BLOOD vol. 108, (4) 1115-1116.
10.1182/blood-2006-06-025957
Martin SI, Marty FM, Fiumara K, Treon SP, Gribben JG, Baden LR(2006). Infectious complications associated with alemtuzumab use for lymphoproliferative disorders. Clin Infect Dis vol. 43, (1) 16-24.
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Grever MR, Dewald GW, Neuberg DS, Reed JC, Kitada S, Flinn IW, Appelbaum FR, Larson RA et al.(2006). Select high risk genetic features predict earlier progression following chemotherapy in chronic lymphocytic leukemia: Prospective randomized trial (Intergroup E2997) to evaluate justification for risk-adapted therapy. J Clin Oncol vol. 24, (18_suppl)
Davies JK, Taussig DC, Oakervee H, Davies AJ, Agrawal SG, Gribben JG, Lister TA, Cavenagh JD(2006). Long-term follow-up after reduced-intensity conditioning allogeneic transplantation for acute myeloid leukemia/myelodysplastic syndrome: late CNS relapses despite graft-versus-host disease. J Clin Oncol vol. 24, (14) e23-e25.
10.1200/JCO.2006.05.7281
Ho VT, Kim HT, Liney D, Milford E, Gribben J, Cutler C, Lee SJ, Antin JH et al. (2006). HLA-C mismatch is associated with inferior survival after unrelated donor non-myeloablative hematopoietic stem cell transplantation. BONE MARROW TRANSPLANTATION. vol. 37, 845-850.
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Le Dieu R, Gribben J(2006). Vaccine- and immune-based therapy in chronic lymphocytic leukemia. Semin Oncol vol. 33, (2) 220-229.
10.1053/j.seminoncol.2005.12.012
Byrd JC, Gribben JG, Peterson BL, Grever MR, Lozanski G, Lucas DM, Lampson B, Larson RA et al.(2006). Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy. J Clin Oncol vol. 24, (3) 437-443.
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Gribben JG, Zahrieh D, Stephans K, Bartlett-Pandite L, Alyea EP, Fisher DC, Freedman AS, Mauch P et al.(2005). Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia. Blood vol. 106, (13) 4389-4396.
10.1182/blood-2005-05-1778
Faderl S, Coutré S, Byrd JC, Dearden C, Denes A, Dyer MJS, Gregory SA, Gribben JG et al.(2005). The evolving role of alemtuzumab in management of patients with CLL. Leukemia vol. 19, (12) 2147-2152.
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Gorgun G, Holderried TAW, Ledieu R, Zahrieh D, Gribben JG (2005). CLL cells in TCL1 transgenic mice induce similar defects in CD4 and CD8 T cells to those observed in patients with CLL. BLOOD. vol. 106, 19A-19A.
Fukuda T, Neuberg DS, Huynh L, Rassenti LZ, Toy TL, Rai KR, Keating MJ, Gribben JG et al. (2005). Expression of T cell co-stimulator (ICOS) and its ligand and disease progression in B-cell chronic lymphocytic leukemia. BLOOD. vol. 106, 826A-826A.
Gribben J, Stephans K, Marshal B (2005). Fludarabine and alemtuzumab versus fludarabine and rituximab in the treatment of relapsed B-cell chronic lymphocytic leukemia: Results from a phase II study. BLOOD. vol. 106, 343B-343B.
Brown JR, Li SL, Kim H, Fisher DC, Cutler C, Ho V, Lee SJ, Ritz J et al. (2005). High levels of early donor chimerism and treatment-responsive disease predict improved progression-free survival following non-myeloablative transplantation for advanced CLL. BLOOD. vol. 106, 166A-167A.
Ledieu R, Gorgun G, Gribben JG (2005). In vivo demonstration of donor idiotype specific T cells that kill primary CLL cells post allogeneic transplant. BLOOD. vol. 106, 23A-23A.
Guinan EC, Gribben JG, Brennan LL, Nadler LM (2005). Patients (Pts) surviving haploidentical stem cell transplantation (SCT) after ex vivo costimulatory blockade to induce anergy experience few long-term complications. BLOOD. vol. 106, 178A-178A.
Mauerer K, Gorgun G, Zahrieh D, Gribben JG (2005). Successful generation of cytotoxic T-cells that kill CLL cells using heteroclitic peptides is independent of the native peptide binding affinity to HLA-A*0201. BLOOD. vol. 106, 20A-21A.
Flinn IW, Byrd JC, Bartlett N, Kipps T, Gribben J, Thomas D, Larson RA, Rai K et al.(2005). Flavopiridol administered as a 24-hour continuous infusion in chronic lymphocytic leukemia lacks clinical activity. LEUKEMIA RES vol. 29, (11) 1253-1257.
10.1016/j.leukres.2005.03.010
Li A, Goldwasser MA, Zhou J, Armstrong SA, Wang H, Dalton V, Fletcher JA, Sallan SE et al.(2005). Distinctive IGH gene segment usage and minimal residual disease detection in infant acute lymphoblastic leukaemias. Br J Haematol vol. 131, (2) 185-192.
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Le Dieu R, Gribben J(2005). CD40 activation: lessons for HIV immunotherapy from malignancies?. J HIV Ther vol. 10, (3) 51-55.
Görgün G, Holderried TAW, Zahrieh D, Neuberg D, Gribben JG(2005). Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells. J Clin Invest vol. 115, (7) 1797-1805.
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Gribben JG, Ryan DP, Boyajian R, Urban RG, Hedley ML, Beach K, Nealon P, Matulonis U et al.(2005). Unexpected association between induction of immunity to the universal tumor antigen CYP1B1 and response to next therapy. Clin Cancer Res vol. 11, (12) 4430-4436.
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Gribben JG, Stephenson JJ, Bartlett NL, Milder MS, Boccia RV, Redfern C, Mizuno VM, Hillson J et al. (2005). A phase II study of Xcellerated T Cells in patients with relapsed or refractory indolent non-Hodgkin's lymphoma (NHL). JOURNAL OF CLINICAL ONCOLOGY. vol. 23, 168S-168S.
Gribben JG (2005). Combination therapy with MabCampath (R): Moving forward. ANNALS OF ONCOLOGY. vol. 16, 255-255.
Mauerer K, Zahrieh D, Gorgun G, Li A, Zhou J, Ansén S, Rassenti LZ, Gribben JG(2005). Immunoglobulin gene segment usage, location and immunogenicity in mutated and unmutated chronic lymphocytic leukaemia. Br J Haematol vol. 129, (4) 499-510.
10.1111/j.1365-2141.2005.05480.x
Zhou J, Mauerer K, Farina L, Gribben JG(2005). The role of the tumor microenvironment in hematological malignancies and implication for therapy. Front Biosci vol. 10, 1581-1596.
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Zhou J, Mauerer K, Farina L, Gribben JG(2005). The role of the tumor microenvironment in hematological malignancies and implication for therapy. Frontiers in Bioscience vol. 10, (2) 1581-1596.
Craiu A, Saito Y, Limon A, Eppich HM, Olson DP, Rodrigues N, Adams GB, Dombkowski D et al.(2005). Flowing cells through pulsed electric fields efficiently purges stem cell preparations of contaminating myeloma cells while preserving stem cell function. BLOOD vol. 105, (5) 2235-2238.
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Davies AJ, Gribben JG(2005). Hematopoietic stem cell transplantation in non-Hodgkin lymphoma. CURR OPIN ORGAN TRAN vol. 10, (1) 35-39.
Alyea EP, Kim HT, Ho V, Cutler C, Gribben J, DeAngelo DJ, Lee SJ, Windawi S et al.(2005). Comparative outcome of nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation for patients older than 50 years of age. BLOOD vol. 105, (4) 1810-1814.
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Gribben JG, Bartlett NL, Stephenson JJ, Milder MS, Boccia RV, Redfern C, Mizuno VM, Berenson RJ et al. (2005). A phase II study of Xcellerated T cells (TM) in patients with relapsed or refractory indolent non-Hodgkin's lymphoma (NHL). BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. vol. 11, 76-76.
10.1016/j.bbmt.2004.12.225
Darby A, Gribben JG(2005). Follicular lymphoma: quantitation of minimal residual disease by PCR of the t(14;18) translocation. Methods Mol Med vol. 115, 315-331.
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Gribben JG(2005). Salvage therapy for CLL and the role of stem cell transplantation. Hematology Am Soc Hematol Educ Program292-298.
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Gricks CS, Zahrieh D, Zauls AJ, Gorgun G, Drandi D, Mauerer K, Neuberg D, Gribben JG(2004). Differential regulation of gene expression following CD40 activation of leukemic compared to healthy B cells. Blood vol. 104, (13) 4002-4009.
10.1182/blood-2004-02-0494
Freedman AS, Gribben JG, Neuberg D, Li S, Kim H, Mauch P, Nadler LM (2004). Autologous bone marrow transplantation for follicular lymphoma in first remission: Long term follow up of two sequential trials with standard dose and high dose CHOP induction. BLOOD. vol. 104, 396B-396B.
Rassenti LZ, Neuberg DS, Keating MJ, Gribben JG, Flinn IW, Rai KR, Byrd JC, Kay NE et al. (2004). CD38 compared with ZAP-70 or immmunoglobulin mutation status as predictor of disease progression in chronic lymphocytic leukemia. BLOOD. vol. 104, 767A-768A.
Holderried TAW, Gorgun G, Gribben JG (2004). Cell contact with CLL cells induces defects in T cell differentiation and effector pathways: Impact of silencing specific cytokine production. BLOOD. vol. 104, 273A-274A.
Kitada S, Reed JC, David MLI, Neuberg DS, Gribben JG, Dewald GW, Flinn IW, Appelbaum FR et al. (2004). Critical molecular studies to strategically plan therapy in chronic lymphocytic leukemia (CLL): Correlating cellular proteins with defined prognostic patient subsets and their response to treatment. BLOOD. vol. 104, 274A-274A.
Mauerer K, Zahrieh D, Gorgun G, Li AH, Zhou JB, Rassenti L, Gribben JG (2004). Distinct VDJ-H gene usage between mutated and unmutated patients in B-CLL: Implications for pathogenesis and correlation with clinical outcome. BLOOD. vol. 104, 278A-278A.
Rizouli V, Zahrieh D, Gorgun G, Holderried TAW, Croce C, Gribben JG (2004). Gene expression profiling identifies similar CD4(+) and CD8(+) T cell defects in TCL1 transgenic mice after development of CLL to those observed in patients with CLL. BLOOD. vol. 104, 55A-55A.
Zhou JB, Xia ZN, Li AH, Gribben JG (2004). Mapping low molecular weight plasma proteome of chronic lymphoblastic leukemia patients using MALDI-TOF mass spectrometry. BLOOD. vol. 104, 528A-528A.
Li AH, Zhou JB, Wang HJ, Goldwasser MA, Lyons C, Sallan SE, Silverman LB, Gribben JG (2004). Molecular analysis of T-cell receptor gene rearrangements in children with T-cell acute lymphoblast leukemia on DFCI ALL consortium protocol 95-01. BLOOD. vol. 104, 308A-308A.
Grever MR, Lucas DM, Dewald GW, Neuberg DS, Flinn IW, Appelbaum FR, Larson RA, Tallman MS et al. (2004). Outcome of treatment with fludarabine versus fludarabine and cyclophosphamide in chronic lymphocytic leukemia (CLL) is adversely impacted by high risk genetic features: Results from ECOG 2997. BLOOD. vol. 104, 950A-951A.
Zhou JB, Li AH, Goldwasser MA, Wang HJ, Dalton V, Lyons C, McBride KD, Sallan SE et al. (2004). Quantitative analysis of minimal residual disease at the completion of induction therapy predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL consortium protocol 95-01. BLOOD. vol. 104, 96A-96A.
Vallat LD, Kemper CA, Park Y, Rassenti LZ, Fisher JW, Gribben JG (2004). Reprogramming the transcriptional response of chronic lymphocytic leukemia (CLL) cells: Influencing the temporal gene regulatory network. BLOOD. vol. 104, 319A-320A.
Byrd JC, Gribben JG, Peterson B, Grever MR, Lozanski G, Lucas DM, Larson RA, Caligiuri MA et al. (2004). Select high risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia (CLL): Preliminary justification for risk-adapted therapy. BLOOD. vol. 104, 139A-139A.
Mauerer K, Zahrieh D, Ansen S, Li AH, Xia ZN, Gribben JG (2004). Somatic hypermutation does not increase the binding affinity of Ig derived peptides to MHC class I or II - Implications for Ig peptide vaccination strategies. BLOOD. vol. 104, 275A-275A.
Vallat LD, Park Y, Rassenti L, Gribben JG (2004). Temporal gene expression after BCR-crosslinking based upon Zap70 related genomic features. BLOOD. vol. 104, 765A-765A.
Widhopf GF, Rassenti LZ, Toy TL, Gribben JG, Wierda WG, Kipps TJ(2004). Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins. Blood vol. 104, (8) 2499-2504.
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Rassenti LZ, Huynh L, Toy TL, Chen L, Keating MJ, Gribben JG, Neuberg DS, Flinn IW et al.(2004). ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. N Engl J Med vol. 351, (9) 893-901.
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Gribben JG(2004). Killing malignant but not normal B cells. BLOOD vol. 104, (3) 601-601.
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Rizouli V, Gribben Jg JG(2004). The role of stem cell transplantation in chronic lymphocytic leukemia. Semin Hematol vol. 41, (3) 246-253.
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Li AH, Rue M, Zhou JB, Wang HJ, Goldwasser MA, Neuberg D, Dalton V, Zuckerman D et al.(2004). Utilization of Ig heavy chain variable, diversity, and joining gene segments in children with B-lineage acute lymphoblastic leukemia: implications for the mechanisms of VDJ recombination and for pathogenesis. BLOOD vol. 103, (12) 4602-4609.
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von Bergwelt-Baildon M, Maecker B, Schultze J, Gribben JG(2004). CD40 activation: potential for specific immunotherapy in B-CLL. Ann Oncol vol. 15, (6) 853-857.
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Gribben JG(2004). Graft purging in autologous bone marrow transplantation: A promise not quite fulfilled - The Alvarnas/Forman article reviewed. ONCOLOGY-NY vol. 18, (7) 876-877.
Armstrong SA, Mabon ME, Silverman LB, Li AH, Gribben JG, Fox EA, Sallan SE, Korsmeyer SJ(2004). FLT3 mutations in childhood acute lymphoblastic leukemia. BLOOD vol. 103, (9) 3544-3546.
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Letestu R, Ugo V, Valensi F, Radford-Weiss I, Nataf J, Levy V, Gribben JG, Troussard X et al.(2004). Prognostic impact of p27KIP1 expression in cyclin D1 positive lymphoproliferative disorders. LEUKEMIA vol. 18, (5) 953-961.
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Brown JR, Gaudet G, Friedberg JW, Neuberg D, Mauch P, Kutok JL, Takvorian T, Fisher DC et al.(2004). Autologous bone marrow transplantation for marginal zone non-Hodgkin's lymphoma. LEUKEMIA LYMPHOMA vol. 45, (2) 315-320.
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Zubair AC, Zahrieh D, Daley H, Schott D, Gribben JG, Alyea EP, Schlossman R, Freedman A et al.(2004). Engraftment of autologous and allogeneic marrow HPCs after myeloablative therapy. Transfusion vol. 44, (2) 253-261.
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Friedberg JW, Dong DA, Li SG, Kim H, Stephans K, Noonan K, Neuberg D, Gribben JG et al. (2004). Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo. LEUKEMIA RESEARCH. vol. 28, 139-147.
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Gribben JG(2004). Death of follicular lymphoma cells - the long and the short of it. BLOOD vol. 103, (2) 374-374.
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Li A, Zhou J, Zuckerman D, Rue M, Dalton V, Lyons C, Silverman LB, Sallan SE et al.(2003). Sequence analysis of clonal immunoglobulin and T-cell receptor gene rearrangements in children with acute lymphoblastic leukemia at diagnosis and at relapse: implications for pathogenesis and for the clinical utility of PCR-based methods of minimal residual disease detection. Blood vol. 102, (13) 4520-4526.
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Alyea E, Weller E, Schlossman R, Canning C, Mauch P, Ng A, Fisher D, Gribben J et al.(2003). Outcome after autologous and allogeneic stem cell transplantation for patients with multiple myeloma: impact of graft-versus-myeloma effect. BONE MARROW TRANSPL vol. 32, (12) 1145-1151.
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O'Brien SM, Gribben JG, Thomas DA, Albitar M, Wierda W, Ferrajoli A, Lerner S, Kantarjian HM et al. (2003). Alemtuzumab for minimal residual disease in CLL. BLOOD. vol. 102, 109A-109A.
Zhou JB, Li AH, Diller L, Gribben JG (2003). Application of molecular markers for minimal residual disease detection in neuroblastoma using real-time PCR technology. BLOOD. vol. 102, 215B-216B.
Drandi D, Lee C, Dal Cin P, Gribben JG (2003). Array-based comparative genomic hybridization identifies deletion at 14q32 as a new prognostic marker in chronic lymphocytic leukemia (CLL). BLOOD. vol. 102, 186A-186A.
Gorgun G, Zahrieh D, Drandi D, Neuberg D, Gribben J (2003). Gene expression profiling reveals defects in genes regulating T cell diffentiation and effector pathways in T cells in patients with CLL. BLOOD. vol. 102, 232A-232A.
Rassenti LZ, Toy TL, Huynh L, Greaves A, Gribben JG, Keating MJ, Rai KR, Flinn IW et al. (2003). High similarity between familial and sporadic cases of chroni lymphocytic leukemia. BLOOD. vol. 102, 670A-670A.
Mauerer K, Gorgun G, Drandi D, Gribben JG (2003). Impact of binding affinity to HLA*A0201 on both generation of cytotoxic T cells and their effector function to kill peptide pulsed APCs and CLL cells. BLOOD. vol. 102, 230A-231A.
Gribben JG, Sequist L, Zahrieh D, Neuberg D, Alyea EP, Fisher DC, Freedman AS, Schlossman RL et al. (2003). Outcome following autologous or allogeneic stem cell transplantation in chronic lymphocytic leukemia. BLOOD. vol. 102, 980A-981A.
Li AH, Armstrong S, Rue M, Wang HJ, Zhou JB, Silverman LB, Sallan SE, Gribben JG (2003). V-H gene usage, incomplete DJ(H) recombinations and MLL rearrangements in infant with B-lineage acute lymphoblastic leukemia: Implications for leukemic transformation occurring at an earlier stage of B cell development. BLOOD. vol. 102, 140A-140A.
Grever MR, Dewald GW, Lucas DM, Neuberg DS, Baird ME, Paternoster SF, Brockman SR, Lozanski G et al. (2003). ZAP-70 protein expression varies by interphase cytogenetic group and may predict disease progression to requirement of treatment among select genetic groups in patients with chronic lymphocytic leukemia (CLL). BLOOD. vol. 102, 73A-73A.
Rassenti LZ, Huynh L, Toy TL, Gribben JG, Keating MJ, Rai KR, Flinn IW, Byrd JC et al. (2003). Zap-70 is a more reliable marker of disease progression risk than immunoglobulin mutation status in chronic lymphocytic leukemia. BLOOD. vol. 102, 34A-34A.
Gribben JG (2003). Indolent B-cell malignancies: Immune recognition and antiself. LEUKEMIA & LYMPHOMA. vol. 44, S77-S83.
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Lee C, Drandi D, Dal Cin P, Gribben J (2003). Prognostic markers in CLL by array-based comparative genomic hybridization. AMERICAN JOURNAL OF HUMAN GENETICS. vol. 73, 218-218.
Friedberg JW, Kim H, Li S, Neuberg D, Boyd K, Daley H, Fisher DC, Gribben JG et al.(2003). Ex vivo B cell depletion using the Eligix B Cell SC system and autologous peripheral blood stem cell transplantation in patients with follicular non-Hodgkin's lymphoma. Bone Marrow Transplant vol. 32, (7) 681-686.
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Battle TE, Castro-Malaspina H, Gribben JG, Frank DA(2003). Sustained complete remission of CLL associated with the use of a Chinese herbal extract: case report and mechanistic analysis. LEUKEMIA RES vol. 27, (9) 859-863.
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Rizouli V, Gribben JG(2003). Role of autologous stem cell transplantation in chronic lymphocytic leukemia. CURR OPIN HEMATOL vol. 10, (4) 306-311.
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Zubair A, Zahrieh D, Daley H, Schott D, Gribben JG, Freedman A, Ritz J(2003). Early neutrophil engraftment following autologous BMT provides a functional predictor of long-term hematopoietic reconstitution. Transfusion vol. 43, (5) 614-621.
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Gricks CS, Gribben JG(2003). Cytotoxic T cell responses against immunoglobulin in malignant and normal B cells: implications for tumor immunity and autoimmunity. Curr Pharm Des vol. 9, (23) 1889-1903.
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Gricks CS, Zauls AJ, Zahrieh D, Chiaretti S, Krackhardt AM, Neuberg D, Gribben JG (2002). Gene expression profiling demonstrates differential regulation of genes controlling cell cycle progression following CD40 activation in healthy B cells compared to CLL cells. BLOOD. vol. 100, 99A-99A.
Gorgun G, Gribben JG (2002). Induction of autologous Th1 response against CLL cells by addition of exogenous interferon during generation of antigen presenting cells gamma. BLOOD. vol. 100, 591A-591A.
Savage KJ, Weng AP, Kutok JL, Pinkus G, Gribben JG (2002). Loss of CD20 expression following treatment with anti-CD20 monoclonal antibody in chronic lymphocytic leukemia. BLOOD. vol. 100, 364B-364B.
Friedberg JW, Dong DA, Li SG, Kim H, Stephans K, Noonan K, Neuberg D, Gribben JG et al. (2002). Oral fludarabine (FMP) is highly active in patients (pts) with previously untreated chronic lymphocytic leukemia (CLL), and leads to increased STAT1 levels in vivo. BLOOD. vol. 100, 388A-388A.
Li AH, Zuckerman D, Zuckerman A, Silverman LB, Sallan SE, Gribben JG (2002). Sequence analysis of clonal IgH and TCR gene rearrangements in children with acute lymphoblastic leukemia at diagnosis and at relapse: Implications for clinical utility of PCR based methods of minimal residual disease detection. BLOOD. vol. 100, 68A-68A.
Ricca I, Compagno M, Ladetto M, Dell'Aquila M, Bandesan P, Omede P, Rocci A, D'antico S et al. (2002). Telomere length loss in hematopoietic stem cells following two consecutive chemotherapy-induced mobilizing regimens. BLOOD. vol. 100, 146B-146B.
Li AH, Neuberg D, Zuckerman D, Zuckerman A, Silverman LB, Sallan SE, Gribben JG (2002). Utilization of Ig heavy-chain variable, diversity and joining gene segments in childhood acute lymphoblastic leukemia. BLOOD. vol. 100, 760A-761A.
Krackhardt AM, Witzens M, Harig S, Hodi FS, Zauls AJ, Chessia M, Barrett P, Gribben JG(2002). Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX. BLOOD vol. 100, (6) 2123-2131.
10.1182/blood-2002-02-0513
Andersen NS, Donovan JW, Zuckerman A, Pedersen L, Geisler C, Gribben JG(2002). Real-time polymerase chain reaction estimation of bone marrow tumor burden using clonal immunoglobulin heavy chain gene and bcl-1/JH rearrangements in mantle cell lymphoma. Exp Hematol vol. 30, (7) 703-710.
10.1016/S0301-472X(02)00807-X
Krackhardt AM, Harig S, Witzens M, Broderick R, Barrett P, Gribben JG(2002). T-cell responses against chronic lymphocytic leukemia cells: implications for immunotherapy. Blood vol. 100, (1) 167-173.
10.1182/blood.v100.1.167
Friedberg JW, Neuberg D, Gribben JG, Fisher DC, Canning C, Koval M, Poor CM, Green LM et al.(2002). Combination immunotherapy with rituximab and interleukin 2 in patients with relapsed or refractory follicular non-Hodgkin's lymphoma. BRIT J HAEMATOL vol. 117, (4) 828-834.
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Ladetto M, Omede P, Sametti S, Donovan JW, Astolfi M, Drandi D, Volpato F, Giaccone L et al.(2002). Real-time polymerase chain reaction in multiple myeloma: Quantitative analysis of tumor contamination of stem cell harvests. EXP HEMATOL vol. 30, (6) 529-536.
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Gribben JG(2002). Monitoring disease in lymphoma and CLL patients using molecular techniques. Best Pract Res Clin Haematol vol. 15, (1) 179-195.
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Howard OM, Gribben JG, Neuberg DS, Grossbard M, Poor C, Janicek MJ, Shipp MA(2002). Rituximab and CHOP induction therapy for newly diagnosed mantle-cell lymphoma: molecular complete responses are not predictive of progression-free survival. J Clin Oncol vol. 20, (5) 1288-1294.
10.1200/JCO.2002.20.5.1288
Gribben JG(2002). Autologous hematopoietic transplantation for low-grade lymphomas. Cytotherapy vol. 4, (3) 205-215.
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Alyea EP, Weller E, Fisher DC, Freedman AS, Gribben JG, Lee S, Schlossman RL, Stone RM et al.(2002). Comparable outcome with T-cell-depleted unrelated-donor versus related-donor allogeneic bone marrow transplantation. Biol Blood Marrow Transplant vol. 8, (11) 601-607.
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Alyea E, Neuberg D, Mauch P, Marcus K, Freedman A, Webb I, Anderson K, Schlossman R et al.(2002). Effect of total body irradiation dose escalation on outcome following T-cell-depleted allogeneic bone marrow transplantation. Biol Blood Marrow Transplant vol. 8, (3) 139-144.
10.1053/bbmt.2002.v8.pm11939603
Webb IJ, Friedberg NW, Gribben JG, Fisher DC, Spitzer T, Neuberg D, Jallow H, Kim H et al.(2002). Effective purging of autologous hematopoietic stem cells using anti-B-cell monoclonal antibody-coated high-density microparticles prior to high-dose therapy for patients with non-Hodgkin's lymphoma. Biol Blood Marrow Transplant vol. 8, (8) 429-434.
10.1053/bbmt.2002.v8.pm12234168
Gilliland DG, Gribben JG(2002). Evaluation of the risk of therapy-related MDS/AML after autologous stem cell transplantation. BIOL BLOOD MARROW TR vol. 8, (1) 9-16.
10.1053/bbmt.2002.v8.pm11846355
Gribben JG(2002). Immunotherapy in the B-cell lymphomas. Cytotherapy vol. 4, (5) 439-440.
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Vonderheide RH, Dutcher JP, Anderson JE, Eckhardt SG, Caron DA, Gribben JG(2001). Cd40 ligand therapy of lymphoma patients - Reply. J CLIN ONCOL vol. 19, (23) 4352-4353.
Krackhardt AM, Witzens M, Zauls AJ, Barrett P, Chessia M, Gribben JG(2001). Differential expression of newly identified CLL-associated antigenes: Ientification of a novel antigen with cancer-testis like expression pattern and genes with tumor-restricted splice variants. BLOOD vol. 98, (11) 731A-731A.
Rai KR, Coutre S, Rizzieri D, Gribben JG, Flinn I, Rabinowe S, Keating MJ, Campath Study Grp(2001). Efficacy and safety of alemtuzumab (Campath-1H) in refractory B-CLL patients treated on a compassionate basis. BLOOD vol. 98, (11) 365A-365A.
Coutre S, Rai KR, Keating MJ, Gribben JG, Flinn I, Rabinowe S, Rizzieri D, Campath Study Grp(2001). Efficacy and safety of alemtuzumab (Campath-1H) used on a compassionate basis in refractory T-PLL. BLOOD vol. 98, (11) 366A-366A.
Krackhardt AM, Witzens M, Zauls AJ, Barrett P, Gribben JG(2001). Identification of novel tumor-associated antigens in CLL - Implications for immunotherapy in CLL. BLOOD vol. 98, (11) 807A-807A.
Zubair AC, Freedman AS, Gribben JG, Friedberg J, Ritz J, Webb IJ(2001). Neutrophil engraftment is a better predictor of long-term hematopoietic function than number of CD34 positive cells infused. BLOOD vol. 98, (11) 323B-323B.
Ladetto M, Omede P, Sametti S, Donovan JW, Drandi D, Giaccone L, Volpato F, Astolfi M et al.(2001). Real time PCR in multiple myeloma: Quantitative analysis of tumor contamination of stem cell harvests. BLOOD vol. 98, (11) 300B-300B.
Lin TS, Zahrieh D, Weller E, Alyea ER, Fisher DC, Gribben JG, Freedman AS, Schlossman RL et al.(2001). Risk factors for CMV reactivation after T-cell depleted allogeneic bone marrow transplantation. BLOOD vol. 98, (11) 480A-481A.
Harig S, Witzens M, Krackhardt AM, Trojan A, Barrett P, Broderick R, Zauls AJ, Gribben JG(2001). Induction of cytotoxic T-cell responses against immunoglobulin V region-derived peptides modified at human leukocyte antigen-A2 binding residues. BLOOD vol. 98, (10) 2999-3005.
10.1182/blood.v98.10.2999
Vonderheide RH, Butler MO, Liu JF, Battle TE, Hirano N, Gribben JG, Frank DA, Schultze JL et al.(2001). CD40 activation of carcinoma cells increases expression of adhesion and major histocompatibility molecules but fails to induce either CD80/CD86 expression or T cell alloreactivity. Int J Oncol vol. 19, (4) 791-798.
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Alyea E, Weller E, Schlossman R, Canning C, Webb I, Doss D, Mauch P, Marcus K et al.(2001). T-cell--depleted allogeneic bone marrow transplantation followed by donor lymphocyte infusion in patients with multiple myeloma: induction of graft-versus-myeloma effect. Blood vol. 98, (4) 934-939.
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Vonderheide RH, Dutcher JP, Anderson JE, Eckhardt SG, Stephans KF, Razvillas B, Garl S, Butine MD et al. (2001). Phase I study of recombinant human CD40 ligand in cancer patients. JOURNAL OF CLINICAL ONCOLOGY. vol. 19, 3280-3287.
10.1200/JCO.2001.19.13.3280
Trojan A, Witzens M, Schultze JL, Vonderheide RH, Harig S, Krackhardt AM, Stahel RA, Gribben JG(2001). Generation of cytotoxic T lymphocytes against native and altered peptides of human leukocyte antigen-A*0201 restricted epitopes from the human epithelial cell adhesion molecule. Cancer Res vol. 61, (12) 4761-4765.
Schultze JL, Anderson KC, Gilleece MH, Gribben JG, Nadler LM(2001). A pilot study of combined immunotherapy with autologous adoptive tumour-specific T-cell transfer, vaccination with CD40-activated malignant B cells and interleukin 2. BRIT J HAEMATOL vol. 113, (2) 455-460.
10.1046/j.1365-2141.2001.02760.x
Soiffer RJ, Weller E, Alyea EP, Mauch P, Webb IL, Fisher DC, Freedman AS, Schlossman RL et al.(2001). CD6+ donor marrow T-cell depletion as the sole form of graft-versus-host disease prophylaxis in patients undergoing allogeneic bone marrow transplant from unrelated donors. J Clin Oncol vol. 19, (4) 1152-1159.
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Ladetto M, Sametti S, Donovan JW, Ferrero D, Astolfi M, Mitterer M, Ricca I, Drandi D et al.(2001). A validated real-time quantitative PCR approach shows a correlation between tumor burden and successful ex vivo purging in follicular lymphoma patients. Exp Hematol vol. 29, (2) 183-193.
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Ladetto M, Sametti S, Donovan JW, Ferrero D, Astolfi M, Mitterer M, Ricca I, Drandi D et al.(2000). An extensively valitaded real-time quantitative PCR approach shows a correlation between tumour burden (tb) and successful ex vivo purging in follicular lymphoma (FL) patients. BLOOD vol. 96, (11) 583A-+.
Donovan JW, Zuckerman A, Waters S, Silverman L, Sallan S, Gribben JG(2000). Analysis of residual disease levels in pediatric acute lymphoblastic leukemia by TaqMan quantitative PCR. BLOOD vol. 96, (11) 314A-314A.
Witzens M, Krackhardt AM, Harig S, Zauls AJ, Donovan JW, Gribben JG(2000). Chronic lymphocytic leukemia antigens elicit specific immune responses in the autologous host. BLOOD vol. 96, (11) 513A-513A.
Soiffer RJ, Weller E, Lee SJ, Alyea EP, Schlossman RL, Gribben JG, Ritz J, Antin JH(2000). Comparative outcomes of cyclosporine/methotrexate and CD6+T cell depletion (TCD) as graft-vs-host disease (GVHD) prophylaxis for allogeneic bone marrow transplantation (BMT) from unrelated donors (URD). BLOOD vol. 96, (11) 415A-415A.
Ash S, Donovan JW, Temel J, Zuckerman A, Grupp SD, Diller L, Gribben JG(2000). Detection of minimal residual disease and assessment of stem cell purging by TaqMan real time PCR quantitation of GAGE expression in patients with neuroblastoma. BLOOD vol. 96, (11) 187A-187A.
Krackhardt AM, Witzens M, Donovan JW, Chessia M, Harig S, Gribben JG(2000). Identification of tumor associated genes in CLL by subtractive hybridization. BLOOD vol. 96, (11) 165B-165B.
Harig S, Witzens M, Trojan A, Krackhardt AM, Broderick R, Barrett P, Donovan JW, Gribben JG(2000). Induction of cytotoxic T-cell responses against immunoglobulin derived peptides modified at HLA-A2 binding residues. BLOOD vol. 96, (11) 830A-830A.
Krackhardt AM, Witzens M, Donovan JW, Chessia M, Harig S, Gribben JG(2000). JM1, isolation and characterization of a novel CLL antigen recognized by autologous and syngeneic IgG antibodies. BLOOD vol. 96, (11) 513A-513A.
Widhopf GF, Marathe CM, Rassenti LZ, Byrd JC, Flinn IW, Gribben JG, Kipps TJ(2000). Lack of correlation between immunoglobulin somatic mutation and expression of CD38 in chronic lymphocytic leukemia. BLOOD vol. 96, (11) 367A-367A.
Grdisa M, Tang RP, Delmer A, Levy V, Gribben JG, Ajchenbaum-Cymbalista F(2000). Ligation of CD40 on B-cell chronic lymphocytic leukemia (B-CLL) cells promotes increased survival but does not impair fludarabine induced apoptosis. BLOOD vol. 96, (11) 159A-159A.
Witzens M, Krackhardt AM, Harig S, Donovan JW, Gribben JG(2000). Overexpression of ribosomal proteins in chronic lymphocytic leukemia identified by subtractive hybridization. BLOOD vol. 96, (11) 168B-168B.
Friedberg JW, Neuberg D, Gribben JG, Canning C, Daley JF, Kuhlman C, Koval M, Donovan J et al.(2000). Phase II study of combination immunotherapy with interleukin-2 (IL-2) and rituximab in patients with relapsed or refractory follicular non-Hodgkin's lymphoma (NHL). BLOOD vol. 96, (11) 730A-731A.
Ladetto M, Omede P, Sametti S, Donovan JW, Astolfi M, Giaccone L, Giaretta F, Volpato F et al.(2000). Real time quantitative PCR shows that peripheral blood stem cell (PBPC) harvests are significantly less contaminated than bone marrow (BM) in multiple myeloma patients (MM). BLOOD vol. 96, (11) 154A-154A.
Krackhardt AM, Harig S, Witzens M, Barrett P, Broderick R, Gribben JG(2000). T cell responses in CLL: Superiority of TH2 responses might contribute to reduced cytotoxic autologous antitumor responses. BLOOD vol. 96, (11) 28A-28A.
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