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Publications:  Dr Richard Grose

Clayton NS, Grose RP(2018). Emerging Roles of Fibroblast Growth Factor 10 in Cancer. Front Genet vol. 9, 499-499.
10.3389/fgene.2018.00499
https://qmro.qmul.ac.uk/handle/123456789/51503
Fearon AE, Carter EP, Clayton NS et al.(2018). PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer. Cell Rep vol. 22, (9) 2469-2481.
10.1016/j.celrep.2018.02.028
Clayton NS, Wilson AS, Laurent EP et al.(2017). Fibroblast growth factor-mediated crosstalk in cancer etiology and treatment. Dev Dyn vol. 246, (7) 493-501.
10.1002/dvdy.24514
Carter EP, Gopsill JA, Gomm JJ et al.(2017). A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer. Breast Cancer Res vol. 19, (1)
10.1186/s13058-017-0843-4
Chioni A-M, Bajwa RT, Grose R(2017). 3D Organotypic Culture Model to Study Components of ERK Signaling. Methods Mol Biol vol. 1487, 255-267.
10.1007/978-1-4939-6424-6_19
Carter E, Gomm JJ, Jones LJ et al. (2016). A 3D in vitro model of the human breast duct: unravelling myoepithelial-luminal interactions in breast cancer. Breast Cancer Research and Treatment. Conference: UK Breast Cancer Research Symposium 2016 vol. 159, 187-188.
10.1007/s10549-016-3898-5
Carapuça EF, Gemenetzidis E, Feig C et al.(2016). Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma. Journal of Pathology vol. 239, (3) 286-296.
10.1002/path.4727
https://qmro.qmul.ac.uk/handle/123456789/13271
GROSE RP, Dawkins JBN, Wang J et al.(2016). Reduced expression of histone methyltransferases KMT2C and KMT2D correlates with improved outcome in pancreatic ductal adenocarcinoma. Cancer Research
10.1158/0008-5472.CAN-16-0481
https://qmro.qmul.ac.uk/handle/123456789/12978
Tanner Y, Grose RP(2016). Dysregulated FGF signalling in neoplastic disorders. Seminars in Cell and Developmental Biology vol. 53, Article C, 126-135.
10.1016/j.semcdb.2015.10.012
Milagre CS, Gopinathan G, Everitt G et al.(2015). Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer. Cancer Res vol. 75, (7) 1255-1264.
10.1158/0008-5472.CAN-14-1801
https://qmro.qmul.ac.uk/handle/123456789/7203
Carter EP, Fearon AE, Grose RP(2015). Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction. Trends Cell Biol vol. 25, (4) 221-233.
10.1016/j.tcb.2014.11.003
Coleman SJ, Bruce C, Chioni A-M et al.(2014). The ins and outs of fibroblast growth factor receptor signalling. Clin Sci (Lond) vol. 127, (4) 217-231.
10.1042/CS20140100
Coleman SJ, Watt J, Arumugam P et al.(2014). Pancreatic cancer organotypics: High throughput, preclinical models for pharmacological agent evaluation. World J Gastroenterol vol. 20, (26) 8471-8481.
10.3748/wjg.v20.i26.8471
https://qmro.qmul.ac.uk/handle/123456789/10915
Yeste-Velasco M, Mao X, Grose R et al.(2014). Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol vol. 232, (5) 566-577.
10.1002/path.4327
Coleman SJ, Chioni A-M, Ghallab M et al.(2014). Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion. EMBO Mol Med vol. 6, (4) 467-481.
10.1002/emmm.201302698
https://qmro.qmul.ac.uk/handle/123456789/13773
Fearon AE, Grose RP(2014). Grb-ing receptor activation by the tail. Nat Struct Mol Biol vol. 21, (2) 113-114.
10.1038/nsmb.2767
Yeste-Velasco M, Mao X, Grose R et al.(2014). Erratum:Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol (2014); 232: 566-577)). Journal of Pathology vol. 234, (1)
10.1002/path.4396
Coleman SJ, Grose RP, Kocher HM(2014). Fibroblast growth factor family as a potential target in the treatment of hepatocellular carcinoma. J Hepatocell Carcinoma vol. 1, 43-54.
10.2147/JHC.S48958
Yeste-Velasco M, Mao X, Grose R et al.(2014). Identification of ZDHHC14 as a novel human tumour suppressor: gene. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34, S90-S90.
Fearon AE, Gould CR, Grose RP(2013). FGFR signalling in women's cancers. Int J Biochem Cell Biol vol. 45, (12) 2832-2842.
10.1016/j.biocel.2013.09.017
Guasti L, Candy Sze WC, McKay T et al.(2013). FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. Molecular and Cellular Endocrinology vol. 371, (1-2) 182-188.
10.1016/j.mce.2013.01.014
Guasti L, Candy Sze WC, McKay T et al.(2013). FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. Mol Cell Endocrinol vol. 371, (1-2) 182-188.
10.1016/j.mce.2013.01.014
Coleman S, Chioni A-M, Ghallab M et al. (2013). Nuclear Translocation of FGFR1 and FGF2 in Pancreatic Stellate Cells Is Necessary for Pancreatic Cancer Cell Invasion. GASTROENTEROLOGY. vol. 144, S98-S98.
Galavotti S, Bartesaghi S, Faccenda D et al.(2013). The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. Oncogene vol. 32, (6) 699-712.
10.1038/onc.2012.111
Robbez-Masson LJ, Bödör C, Jones JL et al.(2013). Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing. PLoS One vol. 8, (11)
10.1371/journal.pone.0078839
https://qmro.qmul.ac.uk/handle/123456789/13790
Meyer M, Müller A-K, Yang J et al.(2012). FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin. J Cell Sci vol. 125, (Pt 23) 5690-5701.
10.1242/jcs.108167
Chioni A-M, Grose R(2012). FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior. J Cell Biol vol. 197, (6) 801-817.
10.1083/jcb.201108077
https://qmro.qmul.ac.uk/handle/123456789/13791
Tsang SM, Brown L, Lin K et al.(2012). Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris. J Pathol vol. 227, (1) 81-93.
10.1002/path.3982
Yeste-Velasco M, Mao X, Grose R et al.(2012). Identification of ZDHHC14 as a novel tumor suppressor gene commonly downregulated in human cancers. CANCER RESEARCH vol. 72,
10.1158/1538-7445.AM2012-4858
Jarosz M, Robbez-Masson L, Chioni A-M et al.(2012). Fibroblast growth factor 22 is not essential for skin development and repair but plays a role in tumorigenesis. PLoS One vol. 7, (6)
10.1371/journal.pone.0039436
https://qmro.qmul.ac.uk/handle/123456789/4825
Coleman SJ, Myrto-Chioni A, Grose RP et al. (2011). Investigating the Role of FGF Signaling in Pancreatic Cancer. GASTROENTEROLOGY. vol. 140, S714-S714.
Chioni A-M, Jones LJ, Grose RP(2011). A novel role for FGFR in breast cancer. CANCER RESEARCH vol. 71,
10.1158/1538-7445.AM2011-1101
Tsang S, Liu L, Teh M et al. (2010). Novel role for human desmoglein 3 in regulating E-cadherin mediated adherens junctions through Src family kinase activation. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 130, S33-S33.
Yang J, Meyer M, Müller A-K et al.(2010). Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis. J Cell Biol vol. 188, (6) 935-952.
10.1083/jcb.200910126
https://qmro.qmul.ac.uk/handle/123456789/13792
Turner N, Grose R(2010). Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer vol. 10, (2) 116-129.
10.1038/nrc2780
Chioni A-M, Shao D, Grose R et al.(2010). Protein kinase A and regulation of neonatal Nav1.5 expression in human breast cancer cells: activity-dependent positive feedback and cellular migration. Int J Biochem Cell Biol vol. 42, (2) 346-358.
10.1016/j.biocel.2009.11.021
D'Amico G, Jones DT, Nye E et al.(2010). Regulation of lymphatic-blood vessel separation by endothelial Rac1 (vol 136, pg 4043, 2009). DEVELOPMENT vol. 137, (2) 359-359.
10.1242/dev.047597
Tsang SM, Liu L, Teh M-T et al.(2010). Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src. PloS ONE vol. 5, (12)
10.1371/journal.pone.0014211
https://qmro.qmul.ac.uk/handle/123456789/11130
D'Amico G, Jones DT, Nye E et al.(2009). Regulation of lymphatic-blood vessel separation by endothelial Rac1. Development vol. 136, (23) 4043-4053.
10.1242/dev.035014
Muller A, Yang J, Meyer M et al. (2009). Control of epidermal barrier function and cutaneous homeostasis by FGF receptors 1 and 2. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 129, S85-S85.
Chioni A-M, Grose R(2009). Negative regulation of fibroblast growth factor 10 (FGF-10) by polyoma enhancer activator 3 (PEA3). Eur J Cell Biol vol. 88, (7) 371-384.
10.1016/j.ejcb.2009.01.004
Chioni A-M, Grose R(2008). Organotypic modelling as a means of investigating epithelial-stromal interactions during tumourigenesis. Fibrogenesis Tissue Repair vol. 1, (1)
10.1186/1755-1536-1-8
https://qmro.qmul.ac.uk/handle/123456789/13751
Grose R, Fantl V, Werner S et al.(2007). The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development. EMBO J vol. 26, (5) 1268-1278.
10.1038/sj.emboj.7601583
Grose R(2006). Fibroblast growth factor receptor 2-IIIb is a critical mediator of intercellular signalling in development and disease. J INVEST DERM SYMP P vol. 11, (1) 142-142.
Grose R, Dickson C(2005). Fibroblast growth factor signaling in tumorigenesis. Cytokine Growth Factor Rev vol. 16, (2) 179-186.
10.1016/j.cytogfr.2005.01.003
Reynolds LE, Conti FJ, Lucas M et al.(2005). Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling. Nat Med vol. 11, (2) 167-174.
10.1038/nm1165
Grose R, Werner S(2004). Wound-healing studies in transgenic and knockout mice. Mol Biotechnol vol. 28, (2) 147-166.
10.1385/MB:28:2:147
Zhang HB, Dessimoz J, Beyer TA et al.(2004). Fibroblast growth factor receptor 1-lllb is dispensable for skin morphogenesis and wound healing. EUR J CELL BIOL vol. 83, (1) 3-11.
10.1078/0171-9335-00355
Grose R(2004). Common ground in the transcriptional profiles of wounds and tumors. Genome Biol vol. 5, (6)
10.1186/gb-2004-5-6-228
https://qmro.qmul.ac.uk/handle/123456789/13771
Young P, Boussadia O, Halfter H et al.(2003). E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles. EMBO J vol. 22, (21) 5723-5733.
10.1093/emboj/cdg560
Petiot A, Conti FJA, Grose R et al.(2003). A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning. Development vol. 130, (22) 5493-5501.
10.1242/dev.00788
Grose R(2003). Epithelial migration: open your eyes to c-Jun. Curr Biol vol. 13, (17) R678-R680.
10.1016/S0960-9822(03)00607-9
Beyer TA, Werner S, Dickson C et al.(2003). Fibroblast growth factor 22 and its potential role during skin development and repair. EXP CELL RES vol. 287, (2) 228-236.
10.1016/S0014-4827(03)00139-3
Werner S, Grose R(2003). Regulation of wound healing by growth factors and cytokines. Physiol Rev vol. 83, (3) 835-870.
10.1152/physrev.2003.83.3.835
Martin P, D'Souza D, Martin J et al.(2003). Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells. Curr Biol vol. 13, (13) 1122-1128.
10.1016/S0960-9822(03)00396-8
Grose R, Werner S(2003). Wound healing studies in transgenic and knockout mice. A review. Methods Mol Med vol. 78, 191-216.
10.1385/1-59259-332-1:191
Wood W, Jacinto A, Grose R et al.(2002). Wound healing recapitulates morphogenesis in Drosophila embryos. NAT CELL BIOL vol. 4, (11) 907-912.
10.1038/ncb875
Grose R, Werner S, Kessler D et al.(2002). A role for endogenous glucocorticoids in wound repair. EMBO Rep vol. 3, (6) 575-582.
10.1093/embo-reports/kvf119
Grose R, Hutter C, Bloch W et al.(2002). A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. Development vol. 129, (9) 2303-2315.
Grose R, Werner S(2002). An aPPARently protective mechanism for keratinocytes in wounded skin. TRENDS MOL MED vol. 8, (4) 149-151.
10.1016/S1471-4914(02)02312-2
Grose R, Harris BS, Cooper L et al.(2002). Immediate early genes krox-24 and krox-20 are rapidly up-regulated after wounding in the embryonic and adult mouse. Dev Dyn vol. 223, (3) 371-378.
10.1002/dvdy.10064
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