Menu
 
Research menu
Jump to menu

Publications:  Dr Richard Grose

Coetzee A, Grose R, Kocher H(2019). Pancreatic Cancer Organotypic Models. Curr Top Microbiol Immunol
10.1007/82_2019_155
Clayton NS, Grose RP(2018). Emerging Roles of Fibroblast Growth Factor 10 in Cancer. Front Genet vol. 9, 499-499.
10.3389/fgene.2018.00499
Fearon AE, Carter EP, Clayton NS, Wilkes EH, Baker A-M, Kapitonova E, Bakhouche BA, Tanner Y et al.(2018). PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer. Cell Rep vol. 22, (9) 2469-2481.
10.1016/j.celrep.2018.02.028
Clayton NS, Wilson AS, Laurent EP, Grose RP, Carter EP(2017). Fibroblast growth factor-mediated crosstalk in cancer etiology and treatment. Dev Dyn vol. 246, (7) 493-501.
10.1002/dvdy.24514
Carter EP, Gopsill JA, Gomm JJ, Jones JL, Grose RP(2017). A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer. Breast Cancer Res vol. 19, (1)
10.1186/s13058-017-0843-4
Chioni A-M, Bajwa RT, Grose R(2017). 3D Organotypic Culture Model to Study Components of ERK Signaling. Methods Mol Biol vol. 1487, 255-267.
10.1007/978-1-4939-6424-6_19
Carter E, Gomm JJ, Jones LJ, Grose RP (2016). A 3D in vitro model of the human breast duct: unravelling myoepithelial-luminal interactions in breast cancer. Breast Cancer Research and Treatment. Conference: UK Breast Cancer Research Symposium 2016 vol. 159, 187-188.
10.1007/s10549-016-3898-5
Carapuça EF, Gemenetzidis E, Feig C, Bapiro TE, Williams MD, Wilson AS, Delvecchio FR, Arumugam P et al.(2016). Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma. Journal of Pathology vol. 239, (3) 286-296.
10.1002/path.4727
GROSE RP, Dawkins JBN, Wang J, maniati, heward, koniali, kocher, martin et al.(2016). Reduced expression of histone methyltransferases KMT2C and KMT2D correlates with improved outcome in pancreatic ductal adenocarcinoma. Cancer Research
10.1158/0008-5472.CAN-16-0481
Tanner Y, Grose RP(2016). Dysregulated FGF signalling in neoplastic disorders. Seminars in Cell and Developmental Biology vol. 53, Article C, 126-135.
10.1016/j.semcdb.2015.10.012
Milagre CS, Gopinathan G, Everitt G, Thompson RG, Kulbe H, Zhong H, Hollingsworth RE, Grose R et al.(2015). Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer. Cancer Res vol. 75, (7) 1255-1264.
10.1158/0008-5472.CAN-14-1801
Carter EP, Fearon AE, Grose RP(2015). Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction. Trends Cell Biol vol. 25, (4) 221-233.
10.1016/j.tcb.2014.11.003
Coleman SJ, Bruce C, Chioni A-M, Kocher HM, Grose RP(2014). The ins and outs of fibroblast growth factor receptor signalling. Clin Sci (Lond) vol. 127, (4) 217-231.
10.1042/CS20140100
Coleman SJ, Watt J, Arumugam P, Solaini L, Carapuca E, Ghallab M, Grose RP, Kocher HM(2014). Pancreatic cancer organotypics: High throughput, preclinical models for pharmacological agent evaluation. World J Gastroenterol vol. 20, (26) 8471-8481.
10.3748/wjg.v20.i26.8471
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljevi¿ N, Chaplin T et al.(2014). Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol vol. 232, (5) 566-577.
10.1002/path.4327
Coleman SJ, Chioni A-M, Ghallab M, Anderson RK, Lemoine NR, Kocher HM, Grose RP(2014). Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasion. EMBO Mol Med vol. 6, (4) 467-481.
10.1002/emmm.201302698
Fearon AE, Grose RP(2014). Grb-ing receptor activation by the tail. Nat Struct Mol Biol vol. 21, (2) 113-114.
10.1038/nsmb.2767
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljevíc N, Chaplin T et al.(2014). Erratum:Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol (2014); 232: 566-577)). Journal of Pathology vol. 234, (1)
10.1002/path.4396
Coleman SJ, Grose RP, Kocher HM(2014). Fibroblast growth factor family as a potential target in the treatment of hepatocellular carcinoma. J Hepatocell Carcinoma vol. 1, 43-54.
10.2147/JHC.S48958
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Marzec J, Vasiljevic N, Chaplin T, Foster JM et al.(2014). Identification of ZDHHC14 as a novel human tumour suppressor: gene. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34, S90-S90.
Fearon AE, Gould CR, Grose RP(2013). FGFR signalling in women's cancers. Int J Biochem Cell Biol vol. 45, (12) 2832-2842.
10.1016/j.biocel.2013.09.017
Guasti L, Candy Sze WC, McKay T, Grose R, King PJ(2013). FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. Molecular and Cellular Endocrinology vol. 371, (1-2) 182-188.
10.1016/j.mce.2013.01.014
Guasti L, Candy Sze WC, McKay T, Grose R, King PJ(2013). FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. Mol Cell Endocrinol vol. 371, (1-2) 182-188.
10.1016/j.mce.2013.01.014
Coleman S, Chioni A-M, Ghallab M, Lemoine N, Grose RP, Kocher H (2013). Nuclear Translocation of FGFR1 and FGF2 in Pancreatic Stellate Cells Is Necessary for Pancreatic Cancer Cell Invasion. GASTROENTEROLOGY. vol. 144, S98-S98.
Galavotti S, Bartesaghi S, Faccenda D, Shaked-Rabi M, Sanzone S, McEvoy A, Dinsdale D, Condorelli F et al.(2013). The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. Oncogene vol. 32, (6) 699-712.
10.1038/onc.2012.111
Robbez-Masson LJ, Bödör C, Jones JL, Hurst HC, Fitzgibbon J, Hart IR, Grose RP(2013). Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing. PLoS One vol. 8, (11)
10.1371/journal.pone.0078839
Meyer M, Müller A-K, Yang J, Moik D, Ponzio G, Ornitz DM, Grose R, Werner S(2012). FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin. J Cell Sci vol. 125, (Pt 23) 5690-5701.
10.1242/jcs.108167
Chioni A-M, Grose R(2012). FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior. J Cell Biol vol. 197, (6) 801-817.
10.1083/jcb.201108077
Tsang SM, Brown L, Lin K, Liu L, Piper K, O'Toole EA, Grose R, Hart IR et al.(2012). Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris. J Pathol vol. 227, (1) 81-93.
10.1002/path.3982
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Chaplin T, Xue L, Xu M et al.(2012). Identification of ZDHHC14 as a novel tumor suppressor gene commonly downregulated in human cancers. CANCER RESEARCH vol. 72,
10.1158/1538-7445.AM2012-4858
Jarosz M, Robbez-Masson L, Chioni A-M, Cross B, Rosewell I, Grose R(2012). Fibroblast growth factor 22 is not essential for skin development and repair but plays a role in tumorigenesis. PLoS One vol. 7, (6)
10.1371/journal.pone.0039436
Coleman SJ, Myrto-Chioni A, Grose RP, Kocher H (2011). Investigating the Role of FGF Signaling in Pancreatic Cancer. GASTROENTEROLOGY. vol. 140, S714-S714.
Chioni A-M, Jones LJ, Grose RP(2011). A novel role for FGFR in breast cancer. CANCER RESEARCH vol. 71,
10.1158/1538-7445.AM2011-1101
Tsang S, Liu L, Teh M, Wheeler A, Piper K, Grose R, Hart I, Garrod D et al. (2010). Novel role for human desmoglein 3 in regulating E-cadherin mediated adherens junctions through Src family kinase activation. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 130, S33-S33.
Yang J, Meyer M, Müller A-K, Böhm F, Grose R, Dauwalder T, Verrey F, Kopf M et al.(2010). Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis. J Cell Biol vol. 188, (6) 935-952.
10.1083/jcb.200910126
Turner N, Grose R(2010). Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer vol. 10, (2) 116-129.
10.1038/nrc2780
Chioni A-M, Shao D, Grose R, Djamgoz MBA(2010). Protein kinase A and regulation of neonatal Nav1.5 expression in human breast cancer cells: activity-dependent positive feedback and cellular migration. Int J Biochem Cell Biol vol. 42, (2) 346-358.
10.1016/j.biocel.2009.11.021
D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V et al.(2010). Regulation of lymphatic-blood vessel separation by endothelial Rac1 (vol 136, pg 4043, 2009). DEVELOPMENT vol. 137, (2) 359-359.
10.1242/dev.047597
Tsang SM, Liu L, Teh M-T, Wheeler A, Grose R, Hart IR, Garrod DR, Fortune F et al.(2010). Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src. PloS ONE vol. 5, (12)
10.1371/journal.pone.0014211
D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V et al.(2009). Regulation of lymphatic-blood vessel separation by endothelial Rac1. Development vol. 136, (23) 4043-4053.
10.1242/dev.035014
Muller A, Yang J, Meyer M, Bohm F, Grose R, Partanen J, Ornitz D, Werner S (2009). Control of epidermal barrier function and cutaneous homeostasis by FGF receptors 1 and 2. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 129, S85-S85.
Chioni A-M, Grose R(2009). Negative regulation of fibroblast growth factor 10 (FGF-10) by polyoma enhancer activator 3 (PEA3). Eur J Cell Biol vol. 88, (7) 371-384.
10.1016/j.ejcb.2009.01.004
Chioni A-M, Grose R(2008). Organotypic modelling as a means of investigating epithelial-stromal interactions during tumourigenesis. Fibrogenesis Tissue Repair vol. 1, (1)
10.1186/1755-1536-1-8
Grose R, Fantl V, Werner S, Chioni A-M, Jarosz M, Rudling R, Cross B, Hart IR et al.(2007). The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development. EMBO J vol. 26, (5) 1268-1278.
10.1038/sj.emboj.7601583
Grose R(2006). Fibroblast growth factor receptor 2-IIIb is a critical mediator of intercellular signalling in development and disease. J INVEST DERM SYMP P vol. 11, (1) 142-142.
Grose R, Dickson C(2005). Fibroblast growth factor signaling in tumorigenesis. Cytokine Growth Factor Rev vol. 16, (2) 179-186.
10.1016/j.cytogfr.2005.01.003
Reynolds LE, Conti FJ, Lucas M, Grose R, Robinson S, Stone M, Saunders G, Dickson C et al.(2005). Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling. Nat Med vol. 11, (2) 167-174.
10.1038/nm1165
Grose R, Werner S(2004). Wound-healing studies in transgenic and knockout mice. Mol Biotechnol vol. 28, (2) 147-166.
10.1385/MB:28:2:147
Zhang HB, Dessimoz J, Beyer TA, Krampert M, Williams LT, Werner S, Grose R(2004). Fibroblast growth factor receptor 1-lllb is dispensable for skin morphogenesis and wound healing. EUR J CELL BIOL vol. 83, (1) 3-11.
10.1078/0171-9335-00355
Grose R(2004). Common ground in the transcriptional profiles of wounds and tumors. Genome Biol vol. 5, (6)
10.1186/gb-2004-5-6-228
Young P, Boussadia O, Halfter H, Grose R, Berger P, Leone DP, Robenek H, Charnay P et al.(2003). E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles. EMBO J vol. 22, (21) 5723-5733.
10.1093/emboj/cdg560
Petiot A, Conti FJA, Grose R, Revest J-M, Hodivala-Dilke KM, Dickson C(2003). A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning. Development vol. 130, (22) 5493-5501.
10.1242/dev.00788
Grose R(2003). Epithelial migration: open your eyes to c-Jun. Curr Biol vol. 13, (17) R678-R680.
10.1016/S0960-9822(03)00607-9
Beyer TA, Werner S, Dickson C, Grose R(2003). Fibroblast growth factor 22 and its potential role during skin development and repair. EXP CELL RES vol. 287, (2) 228-236.
10.1016/S0014-4827(03)00139-3
Werner S, Grose R(2003). Regulation of wound healing by growth factors and cytokines. Physiol Rev vol. 83, (3) 835-870.
10.1152/physrev.2003.83.3.835
Martin P, D'Souza D, Martin J, Grose R, Cooper L, Maki R, McKercher SR(2003). Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells. Curr Biol vol. 13, (13) 1122-1128.
10.1016/S0960-9822(03)00396-8
Grose R, Werner S(2003). Wound healing studies in transgenic and knockout mice. A review. Methods Mol Med vol. 78, 191-216.
10.1385/1-59259-332-1:191
Wood W, Jacinto A, Grose R, Woolner S, Gale J, Wilson C, Martin P(2002). Wound healing recapitulates morphogenesis in Drosophila embryos. NAT CELL BIOL vol. 4, (11) 907-912.
10.1038/ncb875
Grose R, Werner S, Kessler D, Tuckermann J, Huggel K, Durka S, Reichardt HM, Werner S(2002). A role for endogenous glucocorticoids in wound repair. EMBO Rep vol. 3, (6) 575-582.
10.1093/embo-reports/kvf119
Grose R, Hutter C, Bloch W, Thorey I, Watt FM, Fässler R, Brakebusch C, Werner S(2002). A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. Development vol. 129, (9) 2303-2315.
Grose R, Werner S(2002). An aPPARently protective mechanism for keratinocytes in wounded skin. TRENDS MOL MED vol. 8, (4) 149-151.
10.1016/S1471-4914(02)02312-2
Grose R, Harris BS, Cooper L, Topilko P, Martin P(2002). Immediate early genes krox-24 and krox-20 are rapidly up-regulated after wounding in the embryonic and adult mouse. Dev Dyn vol. 223, (3) 371-378.
10.1002/dvdy.10064
Return to top