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Publications:  Prof Karim Brohi

Gall LS, Vulliamy P, Gillespie S, Jones TF, Pierre RSJ, Breukers SE, Gaarder C, Juffermans NP et al.(2019). The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients. Ann Surg vol. 269, (6) 1184-1191.
10.1097/SLA.0000000000002733
Brohi K, Gruen RL, Holcomb JB(2019). Why are bleeding trauma patients still dying?. Intensive Care Med vol. 45, (5) 709-711.
10.1007/s00134-019-05560-x
Schyma BM, Cole E, Wren SM, Brohi K, Brundage SI(2019). Delivering trauma mastery with an international trauma masters. Injury vol. 50, (4) 877-882.
10.1016/j.injury.2019.03.023
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56512
Rehn M, Weaver A, Brohi K, Eshelby S, Green L, Røislien J, Lockey DJ(2019). Effect of Prehospital Red Blood Cell Transfusion on Mortality and Time of Death in Civilian Trauma Patients. Shock vol. 51, (3) 284-288.
10.1097/SHK.0000000000001166
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42284
Juffermans NP, Wirtz MR, Balvers K, Baksaas-Aasen K, van Dieren S, Gaarder C, Naess PA, Stanworth S et al.(2019). Towards patient-specific management of trauma hemorrhage: the effect of resuscitation therapy on parameters of thromboelastometry. J Thromb Haemost vol. 17, (3) 441-448.
10.1111/jth.14378
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54892
Marsden M, Benger J, Brohi K, Curry N, Foley C, Green L, Lucas J, Rossetto A et al.(2019). Coagulopathy, cryoprecipitate and CRYOSTAT-2: realising the potential of a nationwide trauma system for a national clinical trial. Br J Anaesth vol. 122, (2) 164-169.
10.1016/j.bja.2018.10.055
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56069
Crewdson K, Rehn M, Brohi K, Lockey DJ(2019). Response letter to Voelckel et al. Acta Anaesthesiol Scand vol. 63, (1)
10.1111/aas.13283
Crewdson K, Rehn M, Brohi K, Lockey DJ(2019). Response to Burns et al. Acta Anaesthesiol Scand vol. 63, (1)
10.1111/aas.13281
Vulliamy P, Faulkner M, Kirkwood G, West A, O'Neill B, Griffiths MP, Moore F, Brohi K(2018). Temporal and geographic patterns of stab injuries in young people: a retrospective cohort study from a UK major trauma centre. BMJ Open vol. 8, (10)
10.1136/bmjopen-2018-023114
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44003
Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB et al.(2018). Correction: Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Med vol. 15, (10) e1002694-e1002694.
10.1371/journal.pmed.1002694
Glasgow SM, Perkins ZB, Tai NRM, Brohi K, Vasilakis C(2018). Development of a discrete event simulation model for evaluating strategies of red blood cell provision following mass casualty events. European Journal of Operational Research vol. 270, (1) 362-374.
10.1016/j.ejor.2018.03.008
Virdee J, Pafitanis G, Alamouti R, Brohi K, Patel H(2018). Mind the gap: 11 years of train-related injuries at the Royal London Hospital Major Trauma Centre. Ann R Coll Surg Engl vol. 100, (7) 520-528.
10.1308/rcsann.2018.0089
MARSDEN M, CARDEN R, Navaratne L, Smith IM, Penn-Barwell JG, Kraven LM, BROHI KH, TAI N et al.(2018). Outcomes following trauma laparotomy for hypotensive trauma patients: a UK military and civilian perspective. Journal of Trauma and Acute Care Surgery
10.1097/TA.0000000000001988
https://qmro.qmul.ac.uk/xmlui/handle/123456789/50823
Baksaas-Aasen K, Van Dieren S, Balvers K, Juffermans NP, Næss PA, Rourke C, Eaglestone S, Ostrowski SR et al.(2018). Data-driven Development of ROTEM and TEG Algorithms for the Management of Trauma Hemorrhage: A Prospective Observational Multicenter Study. Ann Surg
10.1097/SLA.0000000000002825
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39423
Crewdson K, Rehn M, Brohi K, Lockey DJ(2018). Pre-hospital emergency anaesthesia in awake hypotensive trauma patients: beneficial or detrimental?. Acta Anaesthesiol Scand vol. 62, (4) 504-514.
10.1111/aas.13059
Gall LS, Vulliamy P, Gillespie S, Jones TF, Pierre RSJ, Breukers SE, Gaarder C, Juffermans NP et al.(2018). The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients. Ann Surg
10.1097/SLA.0000000000002733
https://qmro.qmul.ac.uk/xmlui/handle/123456789/37964
PROWLE JR(2018). Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model. Scientific Reports
10.1038/s41598-018-21929-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34319
Harris T, Davenport R, Mak M, Brohi K(2018). The Evolving Science of Trauma Resuscitation. Emerg Med Clin North Am vol. 36, (1) 85-106.
10.1016/j.emc.2017.08.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36561
Aswani A, Manson J, Itagaki K, Chiazza F, Collino M, Wupeng WL, Chan TK, Wong WSF et al.(2018). Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage. Front Immunol vol. 9,
10.3389/fimmu.2018.00891
https://qmro.qmul.ac.uk/xmlui/handle/123456789/37104
VULLIAMY P, GILLESPIE S, ARMSTRONG P, CHAN M, DAVENPORT R, WARNER T, BROHI K (2017). Platelets Shift Towards a Procoagulant and Proin ammatory Phenotype at the Expense of Aggregation During Trauma Hemorrhage: a Potential Role of Extracellular Histones. Circulation. Conference: American Heart Association Scientific Sessions (Anaheim, CA) from: 11/11/2017 to: 15/11/2017, vol. e448-467,
10.1161/CIR.0000000000000546
Tremoleda JL, Watts SA, Reynolds PS, Thiemermann C, Brohi K(2017). Modeling Acute Traumatic Hemorrhagic Shock Injury: Challenges and Guidelines for Preclinical Studies. Shock vol. 48, (6) 610-623.
10.1097/SHK.0000000000000901
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23172
Nevin DG, Brohi K(2017). Permissive hypotension for active haemorrhage in trauma. Anaesthesia vol. 72, (12) 1443-1448.
10.1111/anae.14034
Moran CG, Webb C, Brohi K, Smith M, Willett K(2017). Lessons in planning from mass casualty events in UK. BMJ vol. 359,
10.1136/bmj.j4765
Baksaas-Aasen K, Gall L, Eaglestone S, Rourke C, Juffermans NP, Goslings JC, Naess PA, van Dieren S et al.(2017). iTACTIC - implementing Treatment Algorithms for the Correction of Trauma-Induced Coagulopathy: study protocol for a multicentre, randomised controlled trial. Trials vol. 18, (1) 486-486.
10.1186/s13063-017-2224-9
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28559
Wilson NM, Wall J, Naganathar V, Brohi K, De'Ath HD(2017). Mechanisms Involved in Secondary Cardiac Dysfunction in Animal Models of Trauma and Hemorrhagic Shock. Shock vol. 48, (4) 401-410.
10.1097/SHK.0000000000000882
Brohi K, Davenport RA(2017). In Reply. Anesthesiology vol. 127, (3) 585-586.
10.1097/ALN.0000000000001761
VULLIAMY P, GILLESPIE S, GALL L, GREEN L, Brohi K, Davenport R(2017). Platelet transfusions reduce fibrinolysis but do not restore platelet function during trauma hemorrhage. Journal of Trauma and Acute Care Surgery vol. 83, (3) 388-397.
10.1097/TA.0000000000001520.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22240
Lockey DJ, Brohi K(2017). Pre-hospital thoracotomy and the evolution of pre-hospital critical care for victims of trauma. Injury vol. 48, (9) 1863-1864.
10.1016/j.injury.2017.03.034
Asehnoune K, Balogh Z, Citerio G, Cap A, Billiar T, Stocchetti N, Cohen MJ, Pelosi P et al.(2017). The research agenda for trauma critical care. Intensive Care Med vol. 43, (9) 1340-1351.
10.1007/s00134-017-4895-9
CABRERA CP, MANSON J, SHEPHERD JM, TORRANCE HD, WATSON D, LONGHI MP, HOTI M, PATEL MB et al.(2017). Signatures of Inflammation and Impending Multiple Organ Dysfunction in the Hyperacute Phase of Trauma. PLoS Medicine
10.1371/journal.pmed.1002352
https://qmro.qmul.ac.uk/xmlui/handle/123456789/26246
Sordi R, Nandra KK, Chiazza F, Johnson FL, Cabrera CP, Torrance HD, Yamada N, Patel NSA et al.(2017). Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation. Ann Surg vol. 265, (2) 408-417.
10.1097/SLA.0000000000001664
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19199
Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB et al.(2017). Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Med vol. 14, (7)
10.1371/journal.pmed.1002352
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25043
Brohi K, Schreiber M(2017). The new survivors and a new era for trauma research. PLoS Med vol. 14, (7)
10.1371/journal.pmed.1002354
https://qmro.qmul.ac.uk/xmlui/handle/123456789/26264
Yamada N, Martin L, Zechendorf E, Chiazza F, Varrone B, Collino M, Shepherd J, Heinbockel L et al. (2017). A NOVEL SYNTHETIC, HOST-DEFENCE PEPTIDE PROTECTS AGAINST ORGAN INJURY/DYSFUNCTION IN A RAT-MODEL OF SEVERE HEMORRHAGIC SHOCK. vol. 47, is. 6, pp. 116-117.
Rourke C, Davenport R, Brohi K (2017). Informed consent in acute trauma resuscitation: experiences of a major trauma centre. TRIALS. vol. 18,
https://qmro.qmul.ac.uk/xmlui/handle/123456789/51944
Wilson NM, Wall J, Naganathar V, Brohi K, De'Ath HD(2017). Mechanisms Involved in Secondary Cardiac Dysfunction in Animal Models of Trauma and Haemorrhagic Shock. Shock vol. 48, (4)
10.1097/SHK.0000000000000882
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22680
Balendran CA, Lövgren A, Hansson KM, Nelander K, Olsson M, Johansson KJ, Brohi K, Fries D et al.(2017). Prothrombin time is predictive of low plasma prothrombin concentration and clinical outcome in patients with trauma hemorrhage: analyses of prospective observational cohort studies. Scand J Trauma Resusc Emerg Med vol. 25, (1) 30-30.
10.1186/s13049-016-0332-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35424
Yamada N, Lukas M, Zechendorf E, Purvis G, Chiazzo F, Varone B, Collino M, Shepherd J et al.(2017). Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock. Annals of Surgery
10.1097/SLA.0000000000002186
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23117
GALL L, BROHI K, DAVENPORT R(2017). Diagnosis And Treatment Of Hyperfibrinolysis In Trauma (A European Perspective). Seminars in Thrombosis and Hemostasis
10.1055/s-0036-1598001
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18447
Balvers K, van Dieren S, Baksaas-Aasen K, Gaarder C, Brohi K, Eaglestone S, Stanworth S, Johansson PI et al.(2017). Combined effect of therapeutic strategies for bleeding injury on early survival, transfusion needs and correction of coagulopathy. Br J Surg vol. 104, (3) 222-229.
10.1002/bjs.10330
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23023
Davenport RA, Guerreiro M, Frith D, Rourke C, Platton S, Cohen M, Pearse R, Thiemermann C et al.(2017). Activated Protein C Drives the Hyperfibrinolysis of Acute Traumatic Coagulopathy. Anesthesiology vol. 126, (1) 115-127.
10.1097/ALN.0000000000001428
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17825
Vulliamy PE, Perkins ZB, Brohi K, Manson J(2016). Persistent lymphopenia is an independent predictor of mortality in critically ill emergency general surgical patients. Eur J Trauma Emerg Surg vol. 42, (6) 755-760.
10.1007/s00068-015-0585-x
Perkins ZB, Lendrum RA, Brohi K(2016). Resuscitative endovascular balloon occlusion of the aorta: promise, practice, and progress?. Curr Opin Crit Care vol. 22, (6) 563-571.
10.1097/MCC.0000000000000367
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32154
Perkins ZB, Lendrum RA, Brohi K (2016). Resuscitative endovascular balloon occlusion of the aorta: promise, practice, and progress?. United States , Abstract: java.sql.Clob org.hibernate.engine.jdbc.WrappedClob java.io.Serializable ,
10.1097/MCC.0000000000000367
Shepherd JM, Cole E, Brohi K(2016). Contemporary patterns of multiple organ dysfunction in trauma. Shock
10.1097/SHK.0000000000000779
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17824
De'Ath HD, Oakland K, Brohi K(2016). CT screened arterial calcification as a risk factor for mortality after trauma. Scand J Trauma Resusc Emerg Med vol. 24, (1) 120-120.
10.1186/s13049-016-0317-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16262
Bos L, Schouten L, van Vught L, Wiewel M, Ong D, Cremer O, Artigas A, Martin-Loeches I et al.(2016). ESICM LIVES 2016: part one : Milan, Italy. 1-5 October 2016. Intensive Care Med Exp vol. 4, (Suppl 1)
10.1186/s40635-016-0098-x
Sivakumar S, Taccone FS, Desai KA, Lazaridis C, Skarzynski M, Sekhon M, Henderson W, Griesdale D et al. (2016). ESICM LIVES 2016: part two : Milan, Italy. 1-5 October 2016. Intensive Care Med Exp. Conference: ESICM Lives 2016 (Germany) vol. 4, 30-30.
10.1186/s40635-016-0099-9
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16157
Roberts DJ, Zygun DA, Faris PD, Ball CG, Kirkpatrick AW, Stelfox HT, Indications for Trauma Damage Control Surgery International Study Group (2016). Opinions of Practicing Surgeons on the Appropriateness of Published Indications for Use of Damage Control Surgery in Trauma Patients: An International Cross-Sectional Survey. J Am Coll Surg. vol. 223, 515-529.
10.1016/j.jamcollsurg.2016.06.002
Sharples A, Brohi K(2016). Can clinical prediction tools predict the need for computed tomography in blunt abdominal? A systematic review. Injury vol. 47, (8) 1811-1818.
10.1016/j.injury.2016.05.032
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44845
Glasgow S, Vasilakis C, Perkins Z, Brundage S, Tai N, Brohi K(2016). Managing the surge in demand for blood following mass casualty events: Early automatic restocking may preserve red cell supply. J Trauma Acute Care Surg vol. 81, (1) 50-57.
10.1097/TA.0000000000001101
Cole E, Lecky F, West A, Smith N, Brohi K, Davenport R, ELoTS Study Collaborators(2016). The Impact of a Pan-regional Inclusive Trauma System on Quality of Care. Ann Surg vol. 264, (1) 188-194.
10.1097/SLA.0000000000001393
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22346
Glen J, Constanti M, Brohi K, Guideline Development Group(2016). Assessment and initial management of major trauma: summary of NICE guidance. BMJ vol. 353,
10.1136/bmj.i3051
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25947
Manson J, Cole E, De¿Ath HD, Vulliamy P, Meier U, Pennington D, Brohi K(2016). Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients. Critical Care vol. 20, (1)
10.1186/s13054-016-1341-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13173
Hoffman KP, Playford DE, Grill E, Soberg HL, Brohi K(2016). Minimum data set to measure rehabilitation needs and health outcome after major trauma: application of an international framework. Eur J Phys Rehabil Med vol. 52, (3) 331-346.
Heim C, Cole E, West A, Tai N, Brohi K(2016). Survival prediction algorithms miss significant opportunities for improvement if used for case selection in trauma quality improvement programs. Injury
10.1016/j.injury.2016.05.042
Roberts DJ, Bobrovitz N, Zygun DA, Ball CG, Kirkpatrick AW, Faris PD, Brohi K, D'Amours S et al.(2016). Indications for Use of Damage Control Surgery in Civilian Trauma Patients: A Content Analysis and Expert Appropriateness Rating Study. Ann Surg vol. 263, (5) 1018-1027.
10.1097/SLA.0000000000001347
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22460
Klein AA, Arnold P, Bingham RM, Brohi K, Clark R, Collis R, Gill R, McSporran W et al.(2016). AAGBI guidelines: the use of blood components and their alternatives 2016. Anaesthesia
10.1111/anae.13489
Davenport RA, Brohi K(2016). Cause of trauma-induced coagulopathy. Current Opinion in Anaesthesiology vol. 29, (2) 212-219.
10.1097/ACO.0000000000000295
Stanworth SJ, Davenport R, Curry N, Seeney F, Eaglestone S, Edwards A, Martin K, Allard S et al.(2016). Mortality from trauma haemorrhage and opportunities for improvement in transfusion practice. Br J Surg vol. 103, (4) 357-365.
10.1002/bjs.10052
Gall L, Davenport R, Brohi K (2016). Effect of early tranexamic acid on the coagulation system in patients with suspected traumatic haemorrhage: a prospective cohort study. LANCET. vol. 387, 46-46.
Sordi R, Nandra KK, Chiazza F, Johnson FL, Cabrera CP, Torrance HD, Yamada N, Patel NSA et al.(2016). Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation. Annals of surgery
Sordi R, Nandra KK, Chiazza F, Johnson FL, Cabrera CP, Torrance HD, Yamada N, Patel NSA et al.(2016). Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation. Ann Surg
10.1097/SLA.0000000000001664
Torrance H, Brohi K, Warnes G, Owen HC, Hinds CJ, Pennington DJ, O'Dwyer MJ(2015). T-helper cell polarisation following severe polytrauma. Intensive Care Med Exp vol. 3, (Suppl 1)
10.1186/2197-425X-3-S1-A848
Owen HC, Torrance H, Barnes MR, Brohi K, Knight JC, Hinds CJ, O'Dwyer MJ(2015). The Role of Micrornas in The Development of Hospital Acquired Infection in Polytrauma Patients. Intensive Care Med Exp vol. 3, (Suppl 1)
10.1186/2197-425X-3-S1-A35
Brohi K(2015). The trials of being a national trauma registry. Emerg Med J vol. 32, (12) 909-910.
10.1136/emermed-2015-205424
Owen HC, Torrance HDT, Jones TF, Pearse RM, Hinds CJ, Brohi K, O'Dwyer MJ(2015). Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma. J Trauma Acute Care Surg vol. 79, (5) 766-772.
10.1097/TA.0000000000000850
https://qmro.qmul.ac.uk/xmlui/handle/123456789/8032
Glasgow S, Vasilakis C, Perkins Z, Tai N, Brohi K (2015). DEVELOPING TRANSFUSION BASED STRATEGIES FOR OPTIMISING OUTCOMES FOLLOWING MASS CASUALTY EVENTS USING A DISCRETE EVENT SIMULATION MODELLING APPROACH. SHOCK. vol. 44, 5-6.
Schäfer N, Driessen A, Fröhlich M, Stürmer EK, Maegele M, TACTIC partners(2015). Diversity in clinical management and protocols for the treatment of major bleeding trauma patients across European level I Trauma Centres. Scand J Trauma Resusc Emerg Med vol. 23,
10.1186/s13049-015-0147-6
Wall JM, Tremoleda JL, Thiemermann C, Brohi K (2015). HEART FATTY ACID BINDING PROTEIN (H-FABP) IS A BIOMARKER OF TRAUMA-INDUCED SECONDARY CARDIAC INJURY IN A PRE-CLINICAL MODEL OF TRAUMA-HAEMORRHAGE. SHOCK. vol. 44, 21-22.
Roberts DJ, Bobrovitz N, Zygun DA, Ball CG, Kirkpatrick AW, Faris PD, Parry N, Nicol AJ et al.(2015). Indications for use of thoracic, abdominal, pelvic, and vascular damage control interventions in trauma patients: A content analysis and expert appropriateness rating study. J Trauma Acute Care Surg vol. 79, (4) 568-579.
10.1097/TA.0000000000000821
Shepherd JM, Cole E, Brohi K (2015). PATTERNS OF MULTI-ORGAN DYSFUNCTION IN SEVERELY INJURED PATIENTS WITH HAEMORRHAGE. SHOCK. vol. 44, 21-21.
Vulliamy PE, Perkins ZB, Brohi K, Manson J (2015). SEVERE LYMPHOPENIA IN EMERGENCY SURGICAL PATIENTS IS ASSOCIATED WITH ILLNESS SEVERITY AND MORTALITY. SHOCK. vol. 44, 10-11.
Shepherd JM, Cole E, Brohi K (2015). T-5: PATTERNS OF MULTI-ORGAN DYSFUNCTION IN SEVERELY INJURED PATIENTS WITH HAEMORRHAGE. Shock. vol. 44 Suppl 2,
10.1097/01.shk.0000472070.23771.ef
Frith D, Wall J, Baptista M, Brohi K (2015). THROMBIN GENERATION POTENTIAL DECLINES DURING TRAUMA HAEMORRHAGE DESPITE HAEMOSTATIC RESUSCITATION. SHOCK. vol. 44, 1-2.
Gall L, Davenport R, Brohi K (2015). TRANEXAMIC ACID IS ASSOCIATED WITH ENHANCED CLOT STRENGTH, REDUCED FIBRINOLYSIS AND REDUCED ACUTE TRAUMATIC COAGULOPATHY IN BLEEDING TRAUMA PATIENTS. SHOCK. vol. 44, 4-4.
Sordi R, Nandra KK, Chiazza F, Patel NSA, Brohi K, Collino M, Thiemermann C (2015). TRAUMA ORGAN PROTECTION WITH ARTESUNATE (TOP-ART): PRECLINICAL EFFICACY OF AN ANTIMALARIAL DRUG WITH EXCELLENT SAFETY PROFILE AND PLANNED PHASE II RCT. SHOCK. vol. 44, 1-1.
Jones TF, Gillespie S, Gall LS, Davenport RA, Brohi K (2015). VENOUS THROMBOEMBOLIC EVENTS AFTER TRAUMATIC INJURY ARE ASSOCIATED WITH EARLY CHANGES TO THE FIBRINOLYTIC SYSTEM. SHOCK. vol. 44, 24-24.
Jones TF, Owen HC, Torrance HDT, Pirmadjid N, Brohi K, Hinds CJ, O'Dwyer MJ (2015). MicroRNA-mediated regulation of IL-10, IL-12 and TNFα gene expression in severely injured trauma patients. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. vol. 23,
10.1186/1757-7241-23-S2-O5
Taccone FS, Bunker N, Waldmann C, De Backer D, Brohi K, Jones RG, Vincent J-L(2015). A new device for the prevention of pulmonary embolism in critically ill patients: Results of the European Angel Catheter Registry. J Trauma Acute Care Surg vol. 79, (3) 456-462.
10.1097/TA.0000000000000756
Taccone FS, Bunker N, Waldmann C, De Backer D, Brohi K, Jones RG, Vincent J-L(2015). Nonopioid management of acute pain associated with trauma: Focus on pharmacologic options. JOURNAL OF TRAUMA AND ACUTE CARE SURGERY vol. 79, (3) 456-462.
10.1097/TA.0000000000000756
Whitaker J, West A, Brohi K, Sivapathasuntharam D (2015). Reason for Admission and Outcomes for Older Patients Admitted to a Major Trauma Centre. BRITISH JOURNAL OF SURGERY. vol. 102, 86-86.
Watts S, Nordmann G, Brohi K, Midwinter M, Woolley T, Gwyther R, Wilson C, Poon H et al.(2015). Evaluation of Prehospital Blood Products to Attenuate Acute Coagulopathy of Trauma in a Model of Severe Injury and Shock in Anesthetized Pigs. Shock vol. 44 Suppl 1, 138-148.
10.1097/SHK.0000000000000409
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13171
Campbell HE, Stokes EA, Bargo DN, Curry N, Lecky FE, Edwards A, Woodford M, Seeney F et al.(2015). Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England. Crit Care vol. 19,
10.1186/s13054-015-0987-5
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13170
Naganathar S, De''Ath HD, Wall J, BROHI K(2015). Admission biomarkers of trauma-induced secondary cardiac injury predict adverse cardiac events and are associated with plasma catecholamine levels. Journal of Trauma and Acute Care Surgery vol. 79, (1) 71-77.
10.1097/TA.0000000000000694
Curry N, Rourke C, Davenport R, Beer S, Pankhurst L, Deary A, Thomas H, Llewelyn C et al.(2015). Early cryoprecipitate for major haemorrhage in trauma: a randomised controlled feasibility trial. Br J Anaesth vol. 115, (1) 76-83.
10.1093/bja/aev134
Sordi R, Chiazza F, Johnson FL, Patel NSA, Brohi K, Collino M, Thiemermann C(2015). Inhibition of IκB Kinase Attenuates the Organ Injury and Dysfunction Associated with Hemorrhagic Shock. Mol Med vol. 21, 563-575.
10.2119/molmed.2015.00049
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15622
Colom B, Bodkin JV, Beyrau M, Woodfin A, Ody C, Rourke C, Chavakis T, Brohi K et al.(2015). Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo. Immunity vol. 42, (6) 1075-1086.
10.1016/j.immuni.2015.05.010
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13961
Davenport R, Khan S, Brohi K(2015). Re: Hemostatic resuscitation is neither hemostatic nor resuscitative in trauma hemorrhage: But did they in fact test the effect of hemostatic resuscitation?. J Trauma Acute Care Surg vol. 78, (6) 1237-1238.
10.1097/TA.0000000000000624
Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ(2015). Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients. Annals of Surgery vol. 261, (4) 751-759.
10.1097/SLA.0000000000000653
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Abrams ST, Manson J, Liu T, Alhamdi Y, Brohi K, Wang G, Toh CH(2013). Pro-thrombotic properties of circulating histones cause microcirculatory obstruction and acute respiratory failure. BRITISH JOURNAL OF HAEMATOLOGY vol. 161, (SI, Suplement 1) Article 000317864900012, 6-6.
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Durai R, Agrawal R, Piper K, Brohi K(2009). Wegener's granulomatosis presenting as an abdominal aortic aneurysm: a case report. Cases J vol. 2,
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Cohen MJ, Bir N, Rahn P, Dotson R, Brohi K, Chesebro BB, Mackersie R, Carles M et al. (2009). Protein C Depletion Early After Trauma Increases the Risk of Ventilator-Associated Pneumonia. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE. vol. 67, 1176-1181.
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Brohi K(2009). Trauma induced coagulopathy. J R Army Med Corps vol. 155, (4) 320-322.
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Bent CL, Fotiadis N, Renfrew I, Walsh M, Brohi K, Kyriakides C, Matson M(2009). Total percutaneous aortic repair: midterm outcomes. Cardiovasc Intervent Radiol vol. 32, (3) 449-454.
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Davenport RA, Brohi K(2009). Coagulopathy in trauma patients: importance of thrombocyte function?. Curr Opin Anaesthesiol vol. 22, (2) 261-266.
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Cohen MJ, Brohi K, Calfee CS, Rahn P, Chesebro BB, Christiaans SC, Carles M, Howard M et al.(2009). Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion. CRIT CARE vol. 13, (6) Article R174,
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Greaves P, Konig T, Barber C, Barroso AF, Weaver A, Brohi K, Allard S (2009). Use of 'massive transfusion packs' at a major trauma centre. BRITISH JOURNAL OF HAEMATOLOGY. vol. 145, 80-80.
Hess JR, Brohi K, Dutton RP, Hauser CJ, Holcomb JB, Kluger Y, Mackway-Jones K, Parr MJ et al.(2008). The Coagulopathy of Trauma: A Review of Mechanisms. J TRAUMA vol. 65, (4) 748-754.
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Parr MJ, Bouillon B, Brohi K, Dutton RP, Hauser CJ, Hess JR, Holcomb JB, Kluger Y et al.(2008). Traumatic Coagulopathy: Where are the Good Experimental Models?. J TRAUMA vol. 65, (4) 766-771.
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Brohi K(2008). The Utstein template for uniform reporting of data following major trauma: a valuable tool for establishing a pan-European dataset. Scand J Trauma Resusc Emerg Med vol. 16,
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Kortbeek JB, Al Turki SA, Ali J, Antoine JA, Bouillon B, Brasel K, Brenneman F, Brink PR et al.(2008). Advanced Trauma Life Support, 8th edition, the evidence for change. J TRAUMA vol. 64, (6) 1638-1650.
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Brohi K, Cohen MJ, Ganter MT, Schultz MJ, Levi M, Mackersie RC, Pittet JF (2008). Acute coagulopathy of trauma: Hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE. vol. 64, 1211-1217.
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Ganter MT, Cohen MJ, Brohi K, Chesebro BB, Staudenmayer KL, Rahn P, Christiaans SC, Bir ND et al.(2008). Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?. ANN SURG vol. 247, (2) 320-326.
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Aylwin CJ, Brohi K, Davies GD, Walsh MS(2008). Pre-hospital and in-hospital thoracostomy: indications and complications. Ann R Coll Surg Engl vol. 90, (1) 54-57.
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Frith D, Chesebro B, Patel N, Thiemermann C, Brohi K, Cohen M, Pearse R (2008). Towards a mouse model for acute coagulopathy of trauma/shock. SHOCK. vol. 29, 6-6.
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Bent CL, Matson MB, Sobeh M, Renfrew I, Uppal R, Walsh M, Brohi K, Kyriakides C(2007). Endovascular management of acute blunt traumatic thoracic aortic injury: a single center experience. J Vasc Surg vol. 46, (5) 920-927.
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Ganter MT, Brohi K, Cohen MJ, Shaffer LA, Walsh MC, Stahl GL, Pittet JF(2007). Role of the alternative pathway in the early complement activation following major trauma. SHOCK vol. 28, (1) 29-34.
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Brohi K(2007). Trauma specialist centres. ANN ROY COLL SURG vol. 89, (5) 252-253.
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Brohi K, Cohen MJ, Ganter MT, Matthay MA, Mackersie RC, Pittet JF(2007). Acute traumatic coagulopathy: Initiated by hypoperfusion - Modulated through the protein C pathway?. ANN SURG vol. 245, (5) 812-818.
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Aylwin CJ, König TC, Brennan NW, Shirley PJ, Davies G, Walsh MS, Brohi K(2006). Reduction in critical mortality in urban mass casualty incidents: analysis of triage, surge, and resource use after the London bombings on July 7, 2005. Lancet vol. 368, (9554) 2219-2225.
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Rickard MJFX, Brohi K, Bautz PC(2005). Pancreatic and duodenal injuries: Keep it simple. ANZ J SURG vol. 75, (7) 581-586.
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Brohi K, Healy M, Fotheringham T, Chan O, Aylwin C, Whitley S, Walsh M(2005). Helical computed tomographic scanning for the evaluation of the cervical spine in the unconscious, intubated trauma patient. J Trauma vol. 58, (5) 897-901.
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Brohi K, Singh J, Heron M, Coats T(2003). Acute traumatic coagulopathy. J TRAUMA vol. 54, (6) 1127-1130.
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British Trauma Society(2003). Guidelines for the initial management and assessment of spinal injury. British Trauma Society, 2002. Injury vol. 34, (6) 405-425.
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Walsh M, Brohi K, Cord-Udy C(2003). Splenectomy after major trauma: could more spleens be saved?. ANN ROY COLL SURG vol. 85, (3) 221-222.
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Kyriakides C, Bicknell CD, Walsh M, Brohi K, Nott D, Cheshire NJ (2003). Minimal-access aortic surgery: techniques and early experience. BRITISH JOURNAL OF SURGERY. vol. 90, 495-496.
Brohi K(2003). Use of the internet to improve trauma care. Trauma vol. 5, (2) 117-122.
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