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Publications:  Prof John Marshall

HUANG D, PATEL K, Perez-Garrido S et al.(2018). DNA Origami Nanoarrays for Multivalent Investigations of Cancer Cell Spreading with Nanoscale Spatial Resolution and Single- Molecule Control. ACS Nano
10.1021/acsnano.8b08010
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54850
Anderson RL, Balasas T, Callaghan J et al.(2018). A framework for the development of effective anti-metastatic agents. Nat Rev Clin Oncol
10.1038/s41571-018-0134-8
Fearon AE, Carter EP, Clayton NS et al.(2018). PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer. Cell Rep vol. 22, (9) 2469-2481.
10.1016/j.celrep.2018.02.028
Man YKS, Davies JA, Coughlan L et al.(2018). The Novel Oncolytic Adenoviral Mutant Ad5-3Δ-A20T Retargeted to αvβ6 Integrins Efficiently Eliminates Pancreatic Cancer Cells. Mol Cancer Ther vol. 17, (2) 575-587.
10.1158/1535-7163.MCT-17-0671
Marshall JF(2018). Targeting CDH17 in Cancer: When Blocking the Ligand Beats Blocking the Receptor?. Clin Cancer Res vol. 24, (2) 253-255.
10.1158/1078-0432.CCR-17-2823
Pinnington SJL, Marshall JF, Wheeler AP(2018). Correlative 3D Structured Illumination Microscopy and Single-Molecule Localization Microscopy for Imaging Cancer Invasion. Methods Mol Biol vol. 1764, 253-265.
10.1007/978-1-4939-7759-8_15
Caley M, Martins V, Moore K et al. (2017). Tumour associated macrophage recruitment in SCC. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 137, S250-S250.
10.1016/j.jid.2017.07.531
Hayward M, Allen MD, Gomm JJ et al. (2017). Myoepithelial Cell Phenotype in DCIS Progression: Functional Significance of Integrin alpha v beta 6 and Fibronectin. JOURNAL OF PATHOLOGY. vol. 243, S16-S16.
Raab-Westphal S, Marshall JF, Goodman SL(2017). Integrins as Therapeutic Targets: Successes and Cancers. Cancers (Basel) vol. 9, (9)
10.3390/cancers9090110
https://qmro.qmul.ac.uk/handle/123456789/34005
Hung K-Y, Harris PWR, Desai A et al.(2017). Structure-activity relationship study of the tumour-targeting peptide A20FMDV2 via modification of Lys16, Leu13, and N- and/or C-terminal functionality. Eur J Med Chem vol. 136, 154-164.
10.1016/j.ejmech.2017.05.008
Tod J, Hanley CJ, Morgan MR et al.(2017). Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch. J Pathol vol. 243, (1) 37-50.
10.1002/path.4923
https://qmro.qmul.ac.uk/handle/123456789/33525
Hodgins NO, Al-Jamal WT, Wang JT-W et al.(2017). Investigating in vitro and in vivo αvβ6 integrin receptor-targeting liposomal alendronate for combinatory γδ T cell immunotherapy. J Control Release vol. 256, 141-152.
10.1016/j.jconrel.2017.04.025
https://qmro.qmul.ac.uk/handle/123456789/22659
Sarper M, Allen MD, Gomm J et al.(2017). Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function. Breast Cancer Res vol. 19, (1)
10.1186/s13058-017-0822-9
Rudran B, Desai A, Luzarraga M et al. (2017). Development of non-invasive imaging of integrin alpha-v-beta-6 (alpha v beta 6)-positive lung cancers in advance of testing alpha v beta 6-targeted therapies. Lung Cancer. Conference: British Thoracic Oncology Group Conference 2017 (Dublin, Ireland) from: 25/01/2017 to: 27/01/2017, vol. 103, S4-S4.
https://qmro.qmul.ac.uk/handle/123456789/25184
Whilding LM, Parente-Pereira AC, Zabinski T et al.(2017). Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells. Mol Ther vol. 25, (1) 259-273.
10.1016/j.ymthe.2016.10.012
https://qmro.qmul.ac.uk/handle/123456789/49611
Hayward M, Allen MD, Dreger S et al. (2016). Investigating the Functional Significance of Aberrant alpha v beta 6 and Fibronectin Expression in Myoepithelial Cells: Role in the Progression of DCIS?. JOURNAL OF PATHOLOGY. vol. 240, 28-28.
Caley M, Martins V, Moore K et al. (2016). Loss of Laminin alpha 3 drives SCC invasion via ROCK signalling. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S241-S241.
10.1016/j.jid.2016.06.494
Heuser S, Hufbauer M, Steiger J et al.(2016). The fibronectin/α3β1 integrin axis serves as molecular basis for keratinocyte invasion induced by βHPV. Oncogene vol. 35, (34) 4529-4539.
10.1038/onc.2015.512
Khan Z, Marshall JF(2016). The role of integrins in TGFβ activation in the tumour stroma. Cell and Tissue Research vol. 365, (3) 657-673.
10.1007/s00441-016-2474-y
Caley M, Martins V, Moore K et al. (2016). ROCK and Rac1 signalling in squamous cell carcinoma with loss of laminin 332. BRITISH JOURNAL OF DERMATOLOGY. vol. 174, E51-E51.
Whilding LM, Parente-Pereira AC, Zabinski T et al. (2016). Chimeric antigen receptor T-cells targeting the alpha v beta 6 integrin demonstrate potent antitumor activity in multiple solid tumors. CANCER IMMUNOLOGY RESEARCH. vol. 4,
10.1158/2326-6074.CRICIMTEATIAACR15-B129
Pantelidou C, Man YKS, Coughlan L et al.(2016). Oncolytic adenoviral mutants deleted in the anti-apoptotic E1B19K gene sensitize pancreatic cancer cells to drug-induced DNA damage. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 38, S58-S58.
Slack RJ, Hafeji M, Rogers R et al.(2016). Pharmacological Characterization of the αvβ6 Integrin Binding and Internalization Kinetics of the Foot-and-Mouth Disease Virus Derived Peptide A20FMDV2. Pharmacology vol. 97, (3-4) 114-125.
10.1159/000443180
Martins VL, Caley MP, Moore K et al.(2015). Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC. J Natl Cancer Inst vol. 108, (1)
10.1093/jnci/djv293
https://qmro.qmul.ac.uk/handle/123456789/29087
Paillas S, Desai A, Quetier I et al. (2015). Targeted Radionuclide Therapy using high-LET particle emitter-labeled vectors against alpha-v-beta6-expressing cancers. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. vol. 42, S201-S201.
https://qmro.qmul.ac.uk/handle/123456789/10035
Martins V, Caley M, Moore K et al. (2015). Skin type VII collagen acts as a tumour suppressor by regulating TGF beta and angiogenesis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 135, S28-S28.
https://qmro.qmul.ac.uk/handle/123456789/10961
Caley M, Martins V, Marsh S et al. (2015). Squamous Cell Carcinoma progression and Laminin 332. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 135, S23-S23.
Reader CS, Vallath S, Morton J et al. (2015). Cell lines generated from PDAC transgenic mice reveal integrin alpha v beta 6 modifies the invasive phenotype of pancreatic cancer. CANCER RESEARCH. vol. 75,
10.1158/1538-7445.PANCA2014-B87
Rudran B, Marshall JF (2015). The integrin alpha v beta 6: a new target for therapy in non-small cell Lung cancer. LUNG CANCER. vol. 87, S3-S3.
10.1016/S0169-5002(15)50007-X
https://qmro.qmul.ac.uk/handle/123456789/9506
Allen MD, Marshall JF, Jones JL(2014). αvβ6 Expression in myoepithelial cells: a novel marker for predicting DCIS progression with therapeutic potential. Cancer Res vol. 74, (21) 5942-5947.
10.1158/0008-5472.CAN-14-1841
Caley M, Martins V, Moore K et al. (2014). Diverse roles for laminin 332 subunits in squamous cell carcinoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 134, S19-S19.
Moore KM, Thomas GJ, Duffy SW et al.(2014). Therapeutic targeting of integrin αvβ6 in breast cancer. J Natl Cancer Inst vol. 106, (8)
10.1093/jnci/dju169
https://qmro.qmul.ac.uk/handle/123456789/8829
Elosegui-Artola A, Bazellières E, Allen MD et al.(2014). Rigidity sensing and adaptation through regulation of integrin types. Nat Mater vol. 13, (6) 631-637.
10.1038/nmat3960
https://qmro.qmul.ac.uk/handle/123456789/6445
Moutasim KA, Mellows T, Mellone M et al.(2014). Suppression of Hedgehog signalling promotes pro-tumourigenic integrin expression and function. JOURNAL OF PATHOLOGY vol. 233, (2) 196-208.
10.1002/path.4342
Muhammad H, Taher T, Mullen L et al. (2014). Development of a novel approach for targeted delivery of siRNA to B lymphocytes with a potential application in cancer. HUMAN GENE THERAPY. vol. 25, A5-A5.
Caley M, Martins V, Moore K et al. (2014). Diverse roles for laminin-332 subunits in squamous cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY. vol. 170, E26-E26.
Allen MD, Thomas GJ, Clark S et al.(2014). Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence. Clin Cancer Res vol. 20, (2) 344-357.
10.1158/1078-0432.CCR-13-1504
Haider S, Wang J, Nagano A et al.(2014). A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma. Genome Med vol. 6, (12)
10.1186/s13073-014-0105-3
https://qmro.qmul.ac.uk/handle/123456789/6841
Moore KM, Thomas GJ, Duffy SW et al.(2013). Integrin avb6 is a therapeutic target for high-risk breast cancer and enhances trastuzumab efficacy. CANCER RESEARCH vol. 73,
10.1158/0008-5472.SABCS13-P4-15-01
John AE, Luckett JC, Tatler AL et al.(2013). Preclinical SPECT/CT Imaging of alpha v beta 6 Integrins for Molecular Stratification of Idiopathic Pulmonary Fibrosis. JOURNAL OF NUCLEAR MEDICINE vol. 54, (12) 2146-2152.
10.2967/jnumed.113.120592
Ene-Obong A, Clear AJ, Watt J et al.(2013). Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma. Gastroenterology vol. 145, (5) 1121-1132.
10.1053/j.gastro.2013.07.025
Eccles SA, Aboagye EO, Ali S et al.(2013). Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Research vol. 15, (5)
10.1186/bcr3493
Moore KM, Thomas GJ, Duffy SW et al.(2013). Therapeutic targeting of integrin alpha v beta 6 in high-risk breast cancer. MOLECULAR CANCER RESEARCH vol. 11,
10.1158/1557-3125.ADVBC-B046
Eberlein C, Kendrew J, McDaid K et al.(2013). A human monoclonal antibody 264RAD targeting alpha v beta 6 integrin reduces tumour growth and metastasis, and modulates key biomarkers in vivo. ONCOGENE vol. 32, (37) 4406-4416.
10.1038/onc.2012.460
Caley MP, Martins V, Moore K et al. (2013). Diverse roles for laminin 332 subunits in squamous cell carcinoma. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S64-S64.
Martins VL, Caley MP, Moore K et al. (2013). Loss of type VII collagen in cutaneous SCC increases angiogenesis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 133, S158-S158.
Sarper M, Allen MD, Decock J et al. (2013). MMP-8 Loss Contributes to Altered Myoepithelial Cell Function in DCIS. JOURNAL OF PATHOLOGY. vol. 229, S11-S11.
Ali I, Gautrot J, Caley M et al.(2013). Formation and inhibition of invadopodia in oral squamous cell carcinoma. MOLECULAR BIOLOGY OF THE CELL vol. 24,
Kogelberg H, Miranda E, Burnet J et al.(2013). Generation and characterization of a diabody targeting the αvβ6 integrin. PLoS One vol. 8, (9)
10.1371/journal.pone.0073260
John AE, Luckett JC, Tatler AL et al. (2013). Pre-Clinical Imaging Of The alpha v beta 6 Integrin For Molecular Stratification Of Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 187,
Elosegui-Artola A, Bazellieres E, Allen MD et al.(2013). Rigidity sensing and adaptation through regulation of integrin populations. MOLECULAR BIOLOGY OF THE CELL vol. 24,
Man YKS, DiCara D, Chan N et al.(2013). Structural guided scaffold phage display libraries as a source of bio-therapeutics. PLoS One vol. 8, (8)
10.1371/journal.pone.0070452
John AE, Luckett J, Awas R et al. (2012). TARGETED IN VIVO IMAGING OF THE alpha V beta 6 INTEGRIN IN MICE WITH BLEOMYCIN-INDUCED LUNG FIBROSIS. THORAX. vol. 67, A33-A33.
10.1136/thoraxjnl-2012-202678.072
Awais RO, Mather SJ, John AE et al. (2012). NanoSPECT/CT imaging of pulmonary alpha v beta 6 with [In-111]A20FMDV2 as a surrogate marker for monitoring lung fibrosis. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. vol. 39, S215-S215.
Martins V, Caley M, Moore K et al. (2012). Loss of keratinocyte type VII collagen in SCC increases TGF-beta signalling and angiogenesis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 132, S45-S45.
Dreger SA, Payne SJ, Dawoud M et al. (2012). Up-regulation of alpha v beta 6 integrin and fibronectin EDA in myoepithelial cells contribute to the angiogenic switch in pre-invasive breast cancer. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 93, A24-A24.
Ahmed KO, Allen M, Gomm J et al. (2012). MYOEPITHELIAL CONTROL OF THE INFLAMMATORY MICROENVIRONMENT PROMOTES TRANSITION OF DCIS TO INVASIVE DISEASE. ANNALS OF ONCOLOGY. vol. 23, 19-19.
Martins V, Caley M, Moore K et al. (2012). Loss of type VII collagen in squamous cell carcinoma increases angiogenesis in vitro and in vivo. BRITISH JOURNAL OF DERMATOLOGY. vol. 166, e25-e26.
Lines KE, Chelala C, Dmitrovic B et al.(2012). S100P-binding protein, S100PBP, mediates adhesion through regulation of cathepsin Z in pancreatic cancer cells. Am J Pathol vol. 180, (4) 1485-1494.
10.1016/j.ajpath.2011.12.031
Sarper M, Allen M, Decock J et al. (2012). Loss of MMP-8 Expression Contributes to Altered Myoepithelial Cell Function in DCIS. JOURNAL OF PATHOLOGY. vol. 226, S13-S13.
Wagstaff JL, Rowe ML, Hsieh S-J et al.(2012). NMR relaxation and structural elucidation of peptides in the presence and absence of trifluoroethanol illuminates the critical molecular nature of integrin alpha v beta 6 ligand specificity. RSC ADVANCES vol. 2, (29) 11019-11028.
10.1039/c2ra21655h
Moore KM, Hart IR, Jones LJ et al.(2011). Integrin avb6 Mediates HER2-Driven Invasion in Breast Cancer. CANCER RESEARCH vol. 71,
10.1158/0008-5472.SABCS11-P2-01-05
Martins VL, Moore K, Chen M et al. (2011). Loss of type VII collagen in SCC leads to increased invasion and TGF-beta signalling in vivo. BRITISH JOURNAL OF DERMATOLOGY. vol. 164, 910-910.
Martins V, Moore K, Chen M et al. (2011). Loss of type VII collagen in squamous cell carcinoma leads to increased invasion and TGF-beta signalling in vivo. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 131, S33-S33.
Morgan MR, Jazayeri M, Ramsay AG et al.(2011). Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion. Oncogene vol. 30, (12) 1422-1435.
10.1038/onc.2010.535
Marsh D, Suchak K, Moutasim KA et al.(2011). Stromal features are predictive of disease mortality in oral cancer patients. J Pathol vol. 223, (4) 470-481.
10.1002/path.2830
Moutasim KA, Jenei V, Sapienza K et al.(2011). Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis. J Pathol vol. 223, (3) 366-377.
10.1002/path.2786
Marshall J(2011). Transwell(®) invasion assays. Methods Mol Biol vol. 769, 97-110.
10.1007/978-1-61779-207-6_8
Marsh D, Suchak K, Moutasim KA et al.(2010). Stromal features are predictive of disease mortality in oral cancer patients. J Pathol
10.1002/path.2830
Moutasim KA, Jenei V, Sapienza K et al.(2010). Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis. J Pathol
10.1002/path.2786
Moutasim KA, Jenei V, Sapienza K et al.(2010). Alkaloid-dependent upregulation of AlphavBeta6 integrin promotes oral submucous fibrosis. ORAL DIS vol. 16, (6) 528-528.
Saha A, Ellison D, Thomas GJ et al.(2010). High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6. J Pathol vol. 222, (1) 52-63.
10.1002/path.2745
Froeling FEM, Marshall JF, Kocher HM(2010). Pancreatic cancer organotypic cultures. J Biotechnol vol. 148, (1) 16-23.
10.1016/j.jbiotec.2010.01.008
Sampaio ALF, Zahn G, Leoni G et al.(2010). Inflammation-dependent alpha 5 beta 1 (very late antigen-5) expression on leukocytes reveals a functional role for this integrin in acute peritonitis. J Leukoc Biol vol. 87, (5) 877-884.
10.1189/jlb.1009670
Alexopoulou AN, Leao M, Caballero OL et al.(2010). Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines. Breast Cancer Res vol. 12, (4)
10.1186/bcr2610
Wagstaff JL, Vallath S, Marshall JF et al.(2010). Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin alpha v beta 6 protein-peptide interactions. CHEM COMMUN vol. 46, (40) 7533-7535.
10.1039/c0cc01846e
Payne SJL, Allen M, Dreger S et al. (2009). Myoepithelial Cells in DCIS Exhibit an Altered Phenotype and Promote Angiogenesis. CANCER RESEARCH. vol. 69, 642S-643S.
Robinson SD, Reynolds LE, Kostourou V et al.(2009). Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis. J Biol Chem vol. 284, (49) 33966-33981.
10.1074/jbc.M109.030700
Gagnon MKJ, Hausner SH, Marik J et al.(2009). High-throughput in vivo screening of targeted molecular imaging agents. P NATL ACAD SCI USA vol. 106, (42) 17904-17909.
10.1073/pnas.0906925106
Hausner SH, Abbey CK, Bold RJ et al.(2009). Targeted In vivo Imaging of Integrin alpha(v)beta(6) with an Improved Radiotracer and Its Relevance in a Pancreatic Tumor Model. CANCER RES vol. 69, (14) 5843-5850.
10.1158/0008-5472.CAN-08-4410
Coughlan L, Vallath S, Saha A et al.(2009). In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery. J Virol vol. 83, (13) 6416-6428.
10.1128/JVI.00445-09
Coughlan L, Vallath S, Saha A et al. (2009). An Ad5 Vector Retargeted to alpha v beta 6 Displays Improved Tumour Transduction Combined with Reduced Liver Uptake Following Systemic Delivery. MOLECULAR THERAPY. vol. 17, S323-S323.
Sampaio ALF, Leoni G, Marshall JF et al. (2009). A role for alpha 5 beta 1 integrin in leukocyte accumulation in acute peritonitis. EUR J CLIN INVEST. vol. 39, 22-23.
Hausner SH, Kukis DL, Gagnon MKJ et al.(2009). Evaluation of [Cu-64]Cu-DOTA and [Cu-64]Cu-CB-TE2A Chelates for Targeted Positron Emission Tomography with an alpha(v)beta(6)-Specific Peptide. MOL IMAGING vol. 8, (2) 111-121.
10.2310/7290.2009.00015
Kogelberg H, Tolner B, Thomas GJ et al.(2008). Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus. J Mol Biol vol. 382, (2) 385-401.
10.1016/j.jmb.2008.07.013
Coughlan L, McNeish I, Vassaux G et al. (2008). Transductional retargeting of adenovirus-5 to alphavbeta6 integrin. HUMAN GENE THERAPY. vol. 19, 1102-1102.
Lees DM, Hart IR, Marshall JF(2008). Existence of multiple isoforms of HS1-associated protein X-1 in murine and human tissues. J Mol Biol vol. 379, (4) 645-655.
10.1016/j.jmb.2008.04.020
Roy S, Marshall JF, Speight PM et al. (2008). Role of alpha 9 beta 1 integrin in the regulation of epithelial cell behaviour. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 89, A8-A9.
Marsh D, Dickinson S, Neill GW et al.(2008). alpha v beta 6 integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation. CANCER RES vol. 68, (9) 3295-3303.
10.1158/0008-5472.CAN-08-0174
Dicara D, Burman A, Clark S et al.(2008). Foot-and-mouth disease virus forms a highly stable, EDTA-resistant complex with its principal receptor, integrin alphavbeta6: implications for infectiousness. J Virol vol. 82, (3) 1537-1546.
10.1128/JVI.01480-07
Allen M, Mulligan K, Clark S et al. (2008). De novo expression of alpha(v)beta(6) integrin by myoepithelial cells in ductal carcinoma in situ may be an important marker of disease progression. BREAST CANCER RESEARCH. vol. 10, S16-S16.
10.1186/bcr1912
Jones JL, Thomas GJ, Duffy SW et al. (2007). Expression of alphavbeta6 supersedes Her2 and triple-negative/basal classification of breast cancer and defines novel subgroups with poor survival: implications for breast cancer classification and treatment. BREAST CANCER RESEARCH AND TREATMENT. vol. 106, S11-S11.
Gaggioli C, Hooper S, Hidalgo-Carcedo C et al.(2007). Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol vol. 9, (12) 1392-1400.
10.1038/ncb1658
Ramsay AG, Marshall JF, Hart IR(2007). Integrin trafficking and its role in cancer metastasis. Cancer Metastasis Rev vol. 26, (3-4) 567-578.
10.1007/s10555-007-9078-7
Clark SE, Marshall JE, Hart IR et al. (2007). Molecular profiling of DCIS: identification of distinct subgroups of potential prognostic importance. BREAST CANCER RESEARCH AND TREATMENT. vol. 106, S221-S221.
Hausner SH, DiCara D, Marik J et al.(2007). Use of a peptide derived from foot-and-mouth disease virus for the Noninvasive Imaging of human cancer: Generation and evaluation of 4-[F-18]fluorobenzoyl A20FMDV2 for in vivo imaging of integrin alpha(v)beta(6) expression with positron emission tomography. CANCER RES vol. 67, (16) 7833-7840.
10.1158/0008-5472.CAN-07-1026
Ramsay AG, Keppler MD, Jazayeri M et al.(2007). HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6. Cancer Res vol. 67, (11) 5275-5284.
10.1158/0008-5472.CAN-07-0318
DiCara D, Rapisarda C, Sutcliffe JL et al.(2007). Structure-function analysis of Arg-Gly-Asp helix motifs in alpha v beta 6 integrin ligands. J Biol Chem vol. 282, (13) 9657-9665.
10.1074/jbc.M610461200
Nystrom ML, McCulloch D, Weinreb PH et al.(2006). Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion. Cancer Res vol. 66, (22) 10833-10842.
10.1158/0008-5472.CAN-06-1640
Hart I, Dicara D, Marshall JF(2006). Targeting the invasion-association integrin alphavbeta6 as an anti-carcinoma strategy. EJC SUPPL vol. 4, (12) 82-82.
10.1016/S1359-6349(06)70260-9
Thomas GJ, Nyström ML, Marshall JF(2006). Alphavbeta6 integrin in wound healing and cancer of the oral cavity. J Oral Pathol Med vol. 35, (1) 1-10.
10.1111/j.1600-0714.2005.00374.x
Allen M, Mulligan K, Clark S et al. (2006). Functional analysis of normal and DCIS modified breast myoepithelial cells. BREAST CANCER RESEARCH. vol. 8, S9-S9.
10.1186/bcr1569
Salama I, Mihaimeed F, Marshall J et al. (2006). S100A7 and the basal phenotype in breast cancer. BREAST CANCER RESEARCH AND TREATMENT. vol. 100, S159-S159.
Hooper S, Marshall JF, Sahai E(2006). Tumor cell migration in three dimensions. Methods Enzymol vol. 406, 625-643.
10.1016/S0076-6879(06)06049-6
Ylipalosaari M, Thomas GJ, Nystrom M et al.(2005). alpha v beta 6 integrin down-regulates the MMP-13 expression in oral squamous cell carcinoma cells. EXP CELL RES vol. 309, (2) 273-283.
10.1016/j.yexcr.2005.06.008
Vyas J, Ahmed W, Jayazeri M et al. (2005). Mechanisms of migration and invasion of squamous cell carcinoma in an in vitro model of squamous cell carcinogenesis. BRITISH JOURNAL OF DERMATOLOGY. vol. 152, 843-843.
Vyas JJ, Ahmed W, Jayazeri M et al. (2005). Migration and invasion mechanisms in an in vitro model of squamous cell carcinogenesis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 124, A22-A22.
Nyström ML, Thomas GJ, Stone M et al.(2005). Development of a quantitative method to analyse tumour cell invasion in organotypic culture. J Pathol vol. 205, (4) 468-475.
10.1002/path.1716
Scott KA, Arnott CH, Robinson SC et al.(2004). TNF-alpha regulates epithelial expression of MMP-9 and integrin alphavbeta6 during tumour promotion. A role for TNF-alpha in keratinocyte migration?. Oncogene vol. 23, (41) 6954-6966.
10.1038/sj.onc.1207915
Nystrom M, Stone M, Thomas GJ et al. (2004). A quantitative method for measuring three-dimensional invasion in vitro using organotypic cultures. BRITISH JOURNAL OF CANCER. vol. 91, S58-S58.
Lygoe KA, Norman JT, Marshall JF et al.(2004). alpha v integrins play an important role in myofibroblast differentiation. WOUND REPAIR REGEN vol. 12, (4) 461-470.
10.1111/j.1067-1927.2004.12402.x
Morgan MR, Thomas GJ, Russell A et al.(2004). The integrin cytoplasmic-tail motif EKQKVDLSTDC is sufficient to promote tumor cell invasion mediated by matrix metalloproteinase (MMP)-2 or MMP-9. J Biol Chem vol. 279, (25) 26533-26539.
10.1074/jbc.M401736200
Huntley SP, Davies M, Matthews JB et al.(2004). Attenuated type II TGF-B receptor signalling in human malignant oral keratinocytes induces a less differentiated and more aggressive phenotype that is associated with metastatic dissemination. INT J CANCER vol. 110, (2) 170-176.
10.1002/ijc.20111
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