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Publications:  Dr William Alazawi

ALAZAWI W, Alexander M, Loomis AK, Fairburn-Beech J, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D et al.(2018). Real world data reveal a diagnostic gap in non-alcoholic fatty liver disease. Real world data reveal a diagnostic gap in non-alcoholic fatty liver disease vol. 16, (130)
10.1186/s12916-018-1103-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/43650
Alazawi W, Knolle PA(2018). Interfering with Kupffer cell replenishment: New insights into liver injury. J Hepatol vol. 68, (4) 635-637.
10.1016/j.jhep.2018.01.011
De Silva S, Li W, Kemos P, Brindley JH, Mecci J, Samsuddin S, Chin-Aleong J, Feakins RM et al.(2018). Non-invasive markers of liver fibrosis in fatty liver disease are unreliable in people of South Asian descent. Frontline Gastroenterol vol. 9, (2) 115-121.
10.1136/flgastro-2017-100865
Alazawi W, Bernabe E, Tai D, Janicki T, Kemos P, Samsuddin S, Syn W-K, Gillam D et al.(2017). Periodontitis is associated with significant hepatic fibrosis in patients with non-alcoholic fatty liver disease. PLoS One vol. 12, (12) e0185902-e0185902.
10.1371/journal.pone.0185902
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33443
Sheridan DA, Aithal G, Alazawi W, Allison M, Anstee Q, Cobbold J, Khan S, Fowell A et al.(2017). Care standards for non-alcoholic fatty liver disease in the United Kingdom 2016: a cross-sectional survey. Frontline Gastroenterol vol. 8, (4) 252-259.
10.1136/flgastro-2017-100806
Shetty A, Cho W, Alazawi W, Syn W-K(2017). Methotrexate Hepatotoxicity and the Impact of Nonalcoholic Fatty Liver Disease. Am J Med Sci vol. 354, (2) 172-181.
10.1016/j.amjms.2017.03.014
Ratziu V, Wong VW-S, Lanthier N, Boursier J, Alazawi W, Kluwe J, Genesca J, Andreone P et al. (2017). Hepatic fibrosis is associated with histological activity in nonalcoholic steatohepatitis: an analysis from a large database of screening biopsies in the CENTAUR trial. JOURNAL OF HEPATOLOGY. Conference: ™ EASL 2017 - European Association for the Study of the Liver (Amsterdam, Holland) from: 23/04/2017 to: 19/04/2017, vol. 66, S113-S113.
10.1016/S0168-8278(17)30486-5
De Silva S, Li W, Kemos P, Brindley JH, Feakins R, Chinaleong J, Samsuddin S, Foster GR et al. (2017). Blood-test based assessment of liver fibrosis, but not transient elastography, is less accurate in NAFLD patients of South Asian compared to White ethnicity. JOURNAL OF HEPATOLOGY. vol. 66, S595-S596.
10.1016/S0168-8278(17)31618-5
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25149
Alexander M, Loomis K, Fairburn-Beech J, van der Lei J, Duarte-Salles T, Ansell D, Pasqua A, Rijnbeek P et al. (2017). Incidence and prevalence of recorded non-alcoholic fatty liver disease in four large European primary care databases covering 21.9 million adults. JOURNAL OF HEPATOLOGY. vol. 66, S106-S107.
10.1016/S0168-8278(17)30473-7
Alazawi W, Tai DF, Kemos P, Bernabe E, Janicki T, Gillam D, Samsuddin S, Syn WK et al. (2017). Periodontitis is strongly associated with NAFLD in the NHANES III cohort and in an independent prospective study, is more common in those with biopsy-proven advanced compared to mild liver disease. JOURNAL OF HEPATOLOGY. vol. 66, S596-S596.
10.1016/S0168-8278(17)31619-7
Alazawi W, Pirmadjid N, Lahiri R, Bhattacharya S(2016). Inflammatory and Immune Responses to Surgery and Their Clinical Impact. Ann Surg vol. 264, (1) 73-80.
10.1097/SLA.0000000000001691
Joshi NM, Goodhand J, Alazawi W, Das S, Wilks M, Rampton D (2016). PREDICTING TREATMENT FAILURE IN C.DIFFICILE INFECTION: A PROSPECTIVE OBSERVATIONAL COHORT STUDY. GUT. vol. 65, A209-A209.
10.1136/gutjnl-2016-312388.389
Pirmadjid N, Torrance HDT, Owen HC, Alazawi W, O'Dwyer MJ (2015). Association Between Early Postoperatively Elevated TLR-4 & TLR-5 Gene Expression and Late Nosocomial Infection in Elective High-Risk Hepato-Pancreato-Biliary (HPB) Surgery. BRITISH JOURNAL OF SURGERY. vol. 102, 2-2.
Tai FWD, Syn W-K, Alazawi W(2015). Practical approach to non-alcoholic fatty liver disease in patients with diabetes. Diabet Med vol. 32, (9) 1121-1133.
10.1111/dme.12725
Tai D, Lewis H, Derwa Y, Lillis A, Reynolds T, Maitland K, Hall D, Alazawi W et al. (2015). ONE YEAR MORTALITY OUTCOMES OF PATIENTS WITH LIVER CIRRHOSIS ADMITTED TO A TEACHING HOSPITAL INTENSIVE CARE UNIT. GUT. vol. 64, A448-A449.
10.1136/gutjnl-2015-309861.981
Gill US, Hansi NK, Payaniandy L, Schulz J, Payaniandy D, Alazawi W, Dearden J, Kallis YN et al. (2015). SEQUENTIAL NUC THERAPY FOLLOWING PEGYLATED INTERFERON PROVIDES A GREATER DECLINE IN HBSAG AND POTENTIALLY OFFERS A TREATMENT ADVANTAGE OVER CURRENT THERAPIES. GUT. vol. 64, A113-A113.
10.1136/gutjnl-2015-309861.232
Alazawi W, Heath H, Petts G, Kudu H, Feakins R, O'Brien A, Goldin R, Foster GR (2015). STAT2 IS A KEY INFLAMMATORY MOLECULE IN HUMAN NON-ALCOHOLIC FATTY LIVER DISEASE AND MURINE LIVER INJURY. GUT. vol. 64, A452-A453.
10.1136/gutjnl-2015-309861.990
Lahiri R, Derwa Y, Bashir Z, Giles E, Torrance H, O'Dwyer M, Owen H, O'Brien A et al. (2015). EARLY MONOCYTE DYSFUNCTION IN PATIENTS WHO DEVELOP SYSTEMIC INFLAMMATORY RESPONSE SYNDROME (SIRS) AND SEPSIS AFTER HEPATOPANCREATICOBILIARY SURGERY. JOURNAL OF HEPATOLOGY. vol. 62, S290-S291.
10.1016/S0168-8278(15)30209-9
Lahiri R, Derwa Y, Bashir Z, Giles E, Torrance HD, Owen HC, O'Dwyer MJ, O'Brien A et al.(2015). Systemic Inflammatory Response Syndrome After Major Abdominal Surgery Predicted by Early Upregulation of TLR4 and TLR5. Ann Surg vol. 2015, (3)
10.5966/sctm.2012-0137
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9508
Hull S, Mathur R, Boomla K, Chowdhury TA, Dreyer G, Alazawi W, Robson J(2014). Research into practice: understanding ethnic differences in healthcare usage and outcomes in general practice. Br J Gen Pract vol. 64, (629) 653-655.
10.3399/bjgp14X683053
Alazawi W, Mathur R, Abeysekera K, Hull S, Boomla K, Robson J, Foster GR(2014). Ethnicity and the diagnosis gap in liver disease: a population-based study. Br J Gen Pract vol. 64, (628) e694-e702.
10.3399/bjgp14X682273
https://qmro.qmul.ac.uk/xmlui/handle/123456789/10805
Tai F, Derwa Y, Naik S, Alazawi W(2014). PTH-080 Risk Profile For Non-alcoholic Fatty Liver Disease (nafld) In A Paediatric Specialist Care Setting. Gut vol. 63 Suppl 1, A244-A245.
10.1136/gutjnl-2014-307263.526
Alazawi W, Mathur R, Abeysekera K, Hull S, Boomla K, Robson J, Foster G(2014). PTU-138 Population-based Study Of Ethnicity And The Diagnosis Gap In Liver Disease. Gut vol. 63 Suppl 1,
10.1136/gutjnl-2014-307263.212
Ooi J, Chinthapalli S, O'Toole E, Alazawi W(2014). PWE-142 Is Liver Disease Overlooked In Patients With Psoriasis?. Gut vol. 63 Suppl 1,
10.1136/gutjnl-2014-307263.402
O'Brien AJ, Fullerton JN, Massey KA, Auld G, Sewell G, James S, Newson J, Karra E et al.(2014). Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2. Nat Med vol. 20, (5) 518-523.
10.1038/nm.3516
O'Brien A, Fullerton J, Auld G, James S, Newson J, Karra E, Massey K, Alazawi W et al. (2014). PROSTAGLANDIN E-2 MEDIATES IMMUNOSUPPRESSION IN ACUTELY DECOMPENSATED CIRRHOSIS. JOURNAL OF HEPATOLOGY. vol. 60, S64-S64.
10.1016/S0168-8278(14)60156-2
Alazawi W, Agarwal K, Suddle A, Aluvihare V, Heneghan MA(2013). Maintaining clinical governance when giving telephone advice. Frontline Gastroenterol vol. 4, (4) 270-277.
10.1136/flgastro-2013-100351
Lahiri RP, Abeles A, Burnand KM, Alazawi W, Bhattacharya S, Foster GR, Knowles CH(2013). A cross sectional study of colonic diverticulosis in the London Bangladeshi population. United European Gastroenterol J vol. 1, (3) 191-197.
10.1177/2050640613489282
Joshi NM, Kok K, Alazawi W, Goodhand J, Das SS, Rampton DS (2013). RISES IN BOTH WHITE CELL COUNT AND CRP AT DAY 3 PREDICT FAILURE OF TREATMENT WITH METRONIDAZOLE IN C.DIFFICILE INFECTION. GUT. vol. 62, A215-A216.
10.1136/gutjnl-2013-304907.498
Alazawi W, Agarwal K, Suddle A, Aluvihare V, Heneghan M (2013). WHO CALLS THE LIVER REGISTRAR AT KING'S?. GUT. vol. 62, A283-A284.
10.1136/gutjnl-2013-304907.665
Alazawi W, Heath H, Waters JA, Woodfin A, O'Brien AJ, Scarzello AJ, Ma B, Lopez-Otalora Y et al.(2013). Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis. Proc Natl Acad Sci U S A vol. 110, (21) 8656-8661.
10.1073/pnas.1221652110
Lahiri R, Wong J, Waters J, Bhattacharya S, Foster G, Alazawi W (2013). Increased expression of toll-like receptor (TLR) 4 and TLR5 following complex hepato-pancreatico-biliary (HPB) surgery predicts the development of post-operative systemic inflammatory response syndrome (SIRS). BRITISH JOURNAL OF SURGERY. vol. 100, 20-21.
Lahiri R, Abeles A, Burnand K, Alazawi W, Foster G, Knowles C (2013). The London Bangladeshi community: A population protected against the disease of western civilisation. BRITISH JOURNAL OF SURGERY. vol. 100, 40-40.
Alazawi W, Abeysekera K, Dearden J, Glynn M, Kallis Y, Kennedy P, Marley R, Foster GR et al. (2013). IMPLEMENTING EASL & AASLD GUIDELINES FOR HEPATOCELLULAR CARCINOMA SCREENING IS COST-EFFECTIVE IN LONDON'S ETHNICALLY DIVERSE POPULATION. JOURNAL OF HEPATOLOGY. vol. 58, S397-S397.
10.1016/S0168-8278(13)60966-6
Alazawi W, Lahiri R, Spyrou A, Giles E, Bashir Z, O'Brien A, Stagg A, Waters J et al. (2013). PATIENTS WITH COMPENSATED CIRRHOSIS HAVE SELECTIVE PARESIS OF FLAGELLIN-INDUCED INNATE IMMUNE RESPONSES DUE TO FAILURES IN ERK SIGNALLING. JOURNAL OF HEPATOLOGY. vol. 58, S133-S134.
10.1016/S0168-8278(13)60321-9
Alazawi W, Abeysekera K, Boomla K, Foster GR (2013). POPULATION BASED STUDY OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) SHOWS DISEASE IS MORE COMMON AMONG BANGLADESHIS IN ETHNICALLY DIVERSE BOROUGHS OF LONDON. JOURNAL OF HEPATOLOGY. vol. 58, S530-S530.
10.1016/S0168-8278(13)61314-8
Patel C, Gill U, Alazawi W, Shaw P, Alstead EM, Kallis Y, Kooner P, Marley R et al. (2012). Benchmarking disease activity and progression in Chronic Hepatitis B infected young adults. HEPATOLOGY. vol. 56, 362A-362A.
George PM, Cunningham ME, Galloway-Phillipps N, Badiger R, Alazawi W, Foster GR, Mitchell JA(2012). Endothelin-1 as a mediator and potential biomarker for interferon induced pulmonary toxicity. Pulm Circ vol. 2, (4) 501-504.
10.4103/2045-8932.105039
Alazawi W, Waters JA, Heath H, Woodfin A, O'Brien A, Jacobs M, Goldin R, Nourshargh S et al. (2012). Stat2 loss is associated with enhanced inflammatory cell egress and hepatitis after LPS stimulation despite abolishing inflammatory cytokine production: a novel model of liver inflammation. HEPATOLOGY. vol. 56, 1098A-1099A.
Patel C, Gill US, Alazawi W, Shaw P, Alstead E, Kallis Y, Kooner P, Marley R et al.(2012). EVALUATION OF LIVER FIBROSIS IN YOUNG ADULT PATIENTS WITH CHRONIC HEPATITIS B VIRUS. GUT vol. 61, A133-A133.
10.1136/gutjnl-2012-302514b.148
Alazawi W, Spyrou A, Lahiri R, Waters J, Foster GR(2012). FLAGELLIN-INDUCED IL-6 PRODUCTION IS SELECTIVELY IMPAIRED IN PATIENTS WITH CIRRHOSIS. GUT vol. 61, A130-A130.
10.1136/gutjnl-2012-302514b.141
George PM, Badiger R, Alazawi W, Foster GR, Mitchell JA(2012). Pharmacology and therapeutic potential of interferons. Pharmacol Ther vol. 135, (1) 44-53.
10.1016/j.pharmthera.2012.03.006
Konishi H, Okamoto K, Ohmori Y, Yoshino H, Ohmori H, Ashihara M, Hirata Y, Ohta A et al.(2012). An orally available, small-molecule interferon inhibits viral replication. Sci Rep vol. 2,
10.1038/srep00259
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17931
Alazawi W, Gamero A, Heath H, Smith P, Jacobs M, Waters J, Foster GR(2011). NF kappa B ACTIVATION BY TLR AGONISTS IS DEFICIENT IN MACROPHAGES LACKING STAT2. GUT vol. 60, A43-A43.
10.1136/gutjnl-2011-300857a.93
Buczacki S, Shalhoub J, George PM, Vearncombe LM, Byrne PD, Alazawi W(2011). Benefits of knowledge-based interprofessional communication skills training in medical undergraduate education. JRSM Short Rep vol. 2, (8)
10.1258/shorts.2011.011065
Glyn FJ, Gill U, Alazawi W, Ross V, Kooner P, Marley R, Foster G, Kennedy PT (2011). Efficacy of Combination Tenofovir Plus Lamivudine Versus Tenofovir Monotherapy in Patients With Chronic Hepatitis B Virus. GASTROENTEROLOGY. vol. 140, S455-S455.
Glyn F, Gill US, Alazawi W, Ross V, Kooner P, Marley R, Foster GR, Kennedy PTF (2011). EFFICACY OF COMBINATION TENOFOVIR PLUS LAMIVUDINE VERSUS TENOFOVIR MONOTHERAPY IN PATIENTS WITH CHRONIC HEPATITIS B VIRUS. GUT. vol. 60, A231-A231.
10.1136/gut.2011.239301.488
Goodhand JR, Alazawi W, Rampton D (2011). SYSTEMATIC REVIEW: CLOSTRIDIUM DIFFICILE AND IBD. GUT. vol. 60, A146-A146.
10.1136/gut.2011.239301.309
Goodhand JR, Alazawi W, Rampton DS(2011). Systematic review: Clostridium difficile and inflammatory bowel disease. Aliment Pharmacol Ther vol. 33, (4) 428-441.
10.1111/j.1365-2036.2010.04548.x
ALAZAWI W, Lewis H, Foster GR(2011). Other Liver Viruses. Medicine vol. 39, (9) 561-563.
10.1016/j.mpmed.2011.06.005
Javaid A, Hibbert L, Waters JA, Alazawi W, Foster GR (2010). CAN AN EX VIVO HUMAN LIVER BIOPSY MODEL BE USED TO TEST THE EFFICACY OF DRUGS FOR THE TREATMENT OF HEPATITIS C?. HEPATOLOGY. vol. 52, 1217A-1217A.
Alazawi W, Cunningham M, Dearden J, Foster GR(2010). Systematic review: outcome of compensated cirrhosis due to chronic hepatitis C infection. Aliment Pharmacol Ther vol. 32, (3) 344-355.
10.1111/j.1365-2036.2010.04370.x
Alazawi W, Vearncombe LM(2010). Ready to Excel. Lulu
ALAZAWI W, Foster GR(2010). Combination Therapy for Chronic Hepatitis B Virus Infection: Should we use it ab initio or Sequentially?. Clinical Dilemmas in Viral Liver Disease, Editors: Foster, G, Reddy, KR, Wiley-Blackwell
Alazawi W, Cunningham M, Dearden J, Foster GR (2010). NATURAL HISTORY OF COMPENSATED CIRRHOSIS DUE TO CHRONIC HEPATITIS C INFECTION: A SYSTEMATIC REVIEW. GUT. vol. 59, A101-A101.
10.1136/gut.2009.208967l
Simpson AI, Alazawi W, Warwick S, Sheridan E, Glynn M (2010). Mycobacterium mucogenicum causing central line-related sepsis in a home parenteral nutrition patient. PROCEEDINGS OF THE NUTRITION SOCIETY. vol. 69, E181-E181.
10.1017/S0029665109993776
Alazawi W, Cunningham M, Dearden J, Foster GR (2010). NATURAL HISTORY OF COMPENSATED CIRRHOSIS DUE TO CHRONIC HEPATITIS C INFECTION: A SYSTEMATIC REVIEW. JOURNAL OF HEPATOLOGY. vol. 52, S402-S402.
10.1016/S0168-8278(10)61039-2
Alazawi W, Cottle R, Ross V, Ushiro-Lumb I, Alstead EM, Glynn M, Marley R, Foster GR (2009). SUBSTITUTION OF ADEFOVIR FOR TENOFOVIR IN PATIENTS WITH CHRONIC HBV RECEIVING COMBINATION THERAPY WHO HAVE INCOMPLETE CONTROL OR VIROLOGICAL BREAKTHROUGH - IS IT WORTH-WHILE?. HEPATOLOGY. vol. 50, 501A-501A.
ALAZAWI W(2009). Syncope in a Patient with Noonan Syndrome. Cases in Adult Congenital Heart Disease, Editors: Gatzoulis, MA, Gary D Webb, MD, Craig S Broberg, MD, Churchill Livingstone
Alazawi W, Gamero A, Waters J, Jacobs M, Foster G (2009). STAT2 IS A MAJOR DETERMINANT OF HEPATIC INFLAMMATION AND MORTALITY IN A KNOCKOUT MOUSE MODEL OF PERITONEAL INFLAMMATION. JOURNAL OF HEPATOLOGY. vol. 50, S307-S307.
10.1016/S0168-8278(09)60843-6
Alazawi W, Foster GR(2008). Advances in the diagnosis and treatment of hepatitis B. Curr Opin Infect Dis vol. 21, (5) 508-515.
10.1097/QCO.0b013e32830fb924
Herdman MT, Pett MR, Roberts I, Alazawi WOF, Teschendorff AE, Zhang X-Y, Stanley MA, Coleman N(2006). Interferon-beta treatment of cervical keratinocytes naturally infected with human papillomavirus 16 episomes promotes rapid reduction in episome numbers and emergence of latent integrants. CARCINOGENESIS vol. 27, (11) 2341-2353.
10.1093/carcin/bg1172
Alazawi W, Pett M, Strauss S, Moseley R, Gray J, Stanley M, Coleman N(2004). Genomic imbalances in 70 snap-frozen cervical squamous intraepithelial lesions: associations with lesion grade, state of the HPV16 E2 gene and clinical outcome. Br J Cancer vol. 91, (12) 2063-2070.
10.1038/sj.bjc.6602237
Morgan C, Alazawi W, Sirieix P, Freeman T, Coleman N, Fitzgerald R(2004). In vitro acid exposure has a differential effect on apoptotic and proliferative pathways in a Barrett's adenocarcinoma cell line. Am J Gastroenterol vol. 99, (2) 218-224.
10.1111/j.1572-0241.2004.04054.x
Pett MR, ALAZAWI W, Roberts I, Dowen S, Smith DI, Stanley MA, Coleman N(2004). Acquisition of High-Level Chromosomal Instability Is Associated with Integration of Human Papillomavirus Type 16 in Cervical Keratinocytes. Cancer Research vol. 64, (4) 1359-1368.
10.1158/0008-5472.CAN-03-3214
Alazawi W, Gonzalez M, Abraham J, Arends M, Coleman N, Wilson C(2003). Primary or secondary malignancy? Fingerprint evidence. Clin Oncol (R Coll Radiol) vol. 15, (7) 408-411.
10.1016/S0936-6555(03)00062-1
Pett MR, Alazawi W, Dowen S, Roberts I, Stanley MA, Coleman N (2003). Acquisition of high-level genomic instability is associated with integration of HPV16 in cervical keratinocytes. JOURNAL OF PATHOLOGY. vol. 201, 4A-4A.
Morgan C, Alazawi W, Sirieix P, Freeman T, Coleman N, Fitzgerald R (2003). Immediate and early gene response to in vitro acid exposure in a Barrett's adenocarcinoma cell line. GUT. vol. 52, A44-A45.
ALAZAWI W, Morris LS, Stanley MA, Garrod DR, Coleman N(2003). Altered expression of desmosomal components in high-grade squamous intraepithelial lesions of the cervix. Virchows Archiv: the European Journal of Pathology vol. 443, (1) 51-56.
10.1007/s00428-003-0771-9
Alazawi W, Pett M, Arch B, Scott L, Freeman T, Stanley MA, Coleman N(2002). Changes in cervical keratinocyte gene expression associated with integration of human papillomavirus 16. Cancer Res vol. 62, (23) 6959-6965.
Alazawi W, Pett M, Freeman T, Stanley M, Coleman N(2002). Changes in host cell genome and transcriptome associated with integration of HPV 16 in cervical keratinocytes. J PATHOL vol. 198, 8A-8A.
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