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Publications:  Prof Seif Shaheen

Shaheen SO, Gissler M, Devereux G, Erkkola M, Kinnunen TI, Mcardle H, Sheikh A, Hemminki E et al.(2020). Maternal iron supplementation in pregnancy and asthma in the offspring: follow-up of a randomised trial in Finland. European Respiratory Journal vol. 55, (6)
10.1183/13993003.02335-2019
https://qmro.qmul.ac.uk/xmlui/handle/123456789/65147
Portas L, Pereira M, Shaheen SO, Wyss AB, London SJ, Burney PGJ, Hind M, Dean CH et al.(2020). Lung Development Genes and Adult Lung Function. Am J Respir Crit Care Med
10.1164/rccm.201912-2338OC
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64436
Bédard A, Northstone K, John Henderson A, Shaheen SO(2020). Mediterranean diet during pregnancy and childhood respiratory and atopic outcomes: Birth cohort study. European Respiratory Journal vol. 55, (3)
10.1183/13993003.01215-2019
Shaheen S(2019). Elucidating the causes of asthma: how can we do better?. Lancet Respir Med vol. 7, (8)
10.1016/S2213-2600(19)30225-5
SHAHEEN SO, Lundholm C, Brew B, Almqvist C(2019). Prescribed analgesics in pregnancy and risk of childhood asthma. European Respiratory Journal
10.1183/13993003.01090-2018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57357
Bédard A, Northstone K, Holloway JW, Henderson AJ, Shaheen SO(2018). Maternal dietary antioxidant intake in pregnancy and childhood respiratory and atopic outcomes: Birth cohort study. European Respiratory Journal vol. 52, (2)
10.1183/13993003.00507-2018
Bédard A, Lewis SJ, Burgess S, Henderson AJ, Shaheen SO(2018). Maternal iron status during pregnancy and respiratory and atopic outcomes in the offspring: a Mendelian randomisation study. BMJ Open Respir Res vol. 5, (1) e000275-e000275.
10.1136/bmjresp-2018-000275
Shaheen SO, Macdonald-Wallis C, Lawlor DA, Henderson AJ(2017). Haemoglobin concentrations in pregnancy and respiratory and allergic outcomes in childhood: Birth cohort study. Clinical & Experimental Allergy
10.1111/cea.13034
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34923
Brugha R, Lowe R, Henderson AJ, Holloway JW, Rakyan V, Wozniak E, Mahmud N, Seymour K et al.(2017). DNA methylation profiles between airway epithelium and proxy tissues in children. Acta Paediatrica
10.1111/apa.14027
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25323
Okely JA, Shaheen SO, Weiss A, Gale CR(2017). Wellbeing and chronic lung disease incidence: The Survey of Health, Ageing and Retirement in Europe. PLoS One vol. 12, (7) Article 0181320, e0181320-e0181320.
10.1371/journal.pone.0181320
https://qmro.qmul.ac.uk/xmlui/handle/123456789/33696
SHAHEEN SO, Bedard A(2017). Maternal intake of sugar during pregnancy and childhood respiratory and atopic outcomes. European Respiratory Journal
10.1183/13993003.00073-2017
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24893
Varraso R, Shaheen SO(2017). Could a healthy diet attenuate COPD risk in smokers?. Thorax vol. 72, (6) 491-492.
10.1136/thoraxjnl-2016-209608
Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA(2017). Combined Impact of Smoking and Early Life Exposures on Adult Lung Function Trajectories. Am J Respir Crit Care Med
10.1164/rccm.201703-0506OC
Polanska K, Krol A, Kaluzny P, Ligocka D, Mikolajewska K, Shaheen S, Walton R, Hanke W(2016). Estimation of Saliva Cotinine Cut-Off Points for Active and Passive Smoking during Pregnancy-Polish Mother and Child Cohort (REPRO_PL). Int J Environ Res Public Health vol. 13, (12)
10.3390/ijerph13121216
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18517
Gallo V, Dijk FN, Holloway JW, RIng SM, Koppelman GH, Postma DS, Strachan DP, Granell R et al.(2016). TRPA1 gene polymorphisms and childhood asthma. Pediatric Allergy and Immunology
10.1111/pai.12673
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16322
Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA(2016). The presence of chronic mucus hypersecretion across adult life in relation to chronic obstructive pulmonary disease development. American Journal of Respiratory and Critical Care Medicine vol. 193, (6) 662-672.
10.1164/rccm.201511-2210OC
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18952
Cai Y, Shaheen SO, Hardy R, Kuh D, Hansell AL(2016). Birth weight, early childhood growth and lung function in middle to early old age: 1946 British birth cohort. Thorax vol. 71, (10) 916-922.
10.1136/thoraxjnl-2014-206457
Griffiths M, Goldring S, Griffiths C, Shaheen SO, Martineau A, Cross L, Robinson S, Warner JO et al.(2015). Effects of pre-Natal Vitamin D supplementation with partial correction of Vitamin D deficiency on early life healthcare utilisation: A randomised controlled trial. PLoS ONE vol. 10, (12)
10.1371/journal.pone.0145303
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15406
Shaheen SO, Macdonald-Wallis C, Lawlor DA, Henderson AJ(2015). Hypertensive disorders of pregnancy, respiratory outcomes and atopy in childhood. European Respiratory Journal vol. 47, (1) 156-165.
10.1183/13993003.00643-2015
Lee DCP, Walker SA, Byrne AJ, Gregory LG, Buckley J, Bush A, Shaheen SO, Saglani S et al.(2015). Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life. Thorax vol. 70, (6) 528-536.
10.1136/thoraxjnl-2014-205280
Shaheen SO, Rutterford CM, Lewis SJ, Ring SM, Holloway JW, Golding J, Henderson AJ(2015). Maternal selenium status in pregnancy, offspring glutathione peroxidase 4 genotype, and childhood asthma. J Allergy Clin Immunol vol. 135, (4) 1083-5.e3.
10.1016/j.jaci.2014.10.035
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24343
Shaheen SO(2015). Acetaminophen and childhood asthma: pill-popping at our peril?. J Allergy Clin Immunol vol. 135, (2) 449-450.
10.1016/j.jaci.2014.10.030
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6692
Shaheen SO(2014). Antioxidants and respiratory disease: the uric acid paradox. Thorax vol. 69, (11) 978-979.
10.1136/thoraxjnl-2014-205751
Janha RE, Worwui A, Linton KJ, Shaheen SO, Sisay-Joof F, Walton RT(2014). Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolution. BMC Evol Biol vol. 14,
10.1186/1471-2148-14-71
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6565
Okubo H, Shaheen SO, Ntani G, Jameson KA, Syddall HE, Sayer AA, Dennison EM, Cooper C et al.(2014). Processed meat consumption and lung function: Modification by antioxidants and smoking. European Respiratory Journal vol. 43, (4) 972-982.
10.1183/09031936.00109513
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7970
Vawda S, Mansour R, Takeda A, Funnell P, Kerry S, Mudway I, Jamaludin J, Shaheen S et al.(2014). Associations between inflammatory and immune response genes and adverse respiratory outcomes following exposure to outdoor air pollution: A huge systematic review. American Journal of Epidemiology vol. 179, (4) 432-442.
10.1093/aje/kwt269
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6930
Wills AK, Shaheen SO, Granell R, Henderson AJ, Fraser WD, Lawlor DA(2013). Maternal 25-hydroxyvitamin D and its association with childhood atopic outcomes and lung function. Clinical and Experimental Allergy vol. 43, (10) 1180-1188.
10.1111/cea.12172
https://qmro.qmul.ac.uk/xmlui/handle/123456789/7969
Dennison EM, Dhanwal DK, Shaheen SO, Azagra R, Reading I, Jameson KA, Sayer AA, Cooper C(2013). Is lung function associated with bone mineral density? Results from the Hertfordshire Cohort Study. Archives of Osteoporosis vol. 8, (1-2)
10.1007/s11657-012-0115-y
Goldring ST, Griffiths CJ, Martineau AR, Robinson S, Yu C, Poulton S, Kirkby JC, Stocks J et al.(2013). Prenatal vitamin d supplementation and child respiratory health: a randomised controlled trial. PLoS One vol. 8, (6)
10.1371/journal.pone.0066627
https://qmro.qmul.ac.uk/xmlui/handle/123456789/4979
Shaheen S, Rutterford C, Zuccolo L, Ring S, Smith GD, Henderson J(2012). Prenatal alcohol exposure and childhood atopic disease: A Mendelian randomisation approach. EUROPEAN RESPIRATORY JOURNAL vol. 40,
10.1016/j.jaci.2013.04.051
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24850
Relton CL, Groom A, St. Pourcain B, Sayers AE, Swan DC, Embleton ND, Pearce MS, Ring SM et al.(2012). DNA methylation patterns in cord blood DNA and body size in childhood. PLoS ONE vol. 7, (3)
10.1371/journal.pone.0031821
https://qmro.qmul.ac.uk/xmlui/handle/123456789/5317
Shaheen SO, Martineau AR(2012). Vitamin D and chronic obstructive pulmonary disease: justified optimism or false hope?. Am J Respir Crit Care Med vol. 185, (3) 239-241.
10.1164/rccm.201111-2014ED
Soler Artigas M, Wain LV, Repapi E, Obeidat M, Sayers I, Burton PR, Johnson T, Zhao JH et al.(2011). Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med vol. 184, (7) 786-795.
10.1164/rccm.201102-0192OC
Shaheen SO, Jameson KA, Robinson SM, Boucher BJ, Syddall HE, Sayer AA, Cooper C, Holloway JW et al.(2011). Relationship of vitamin D status to adult lung function and COPD. Thorax vol. 66, (8) 692-698.
10.1136/thx.2010.155234
Shaheen SO(2011). Commentary: Paracetamol and asthma--lessons from the antibiotic hypothesis?. Int J Epidemiol vol. 40, (3) 667-669.
10.1093/ije/dyr070
Shaheen SO, Newson RB, Ring SM, Rose-Zerilli MJ, Holloway JW, Henderson AJ(2010). Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma. J Allergy Clin Immunol vol. 126, (6) 1141-8.e7.
10.1016/j.jaci.2010.08.047
Greenough A, Shaheen SO, Shennan A, Seed PT, Poston L(2010). Respiratory outcomes in early childhood following antenatal vitamin C and E supplementation. Thorax vol. 65, (11) 998-1003.
10.1136/thx.2010.139915
Henderson AJ, Newson RB, Rose-Zerilli M, Ring SM, Holloway JW, Shaheen SO(2010). Maternal Nrf2 and gluthathione-S-transferase polymorphisms do not modify associations of prenatal tobacco smoke exposure with asthma and lung function in school-aged children. Thorax vol. 65, (10) 897-902.
10.1136/thx.2009.125856
Shaheen SO, Jameson KA, Syddall HE, Aihie Sayer A, Dennison EM, Cooper C, Robinson SM, Hertfordshire Cohort Study Group(2010). The relationship of dietary patterns with adult lung function and COPD. Eur Respir J vol. 36, (2) 277-284.
10.1183/09031936.00114709
Shaheen SO, Newson RB, Smith GD, Henderson AJ(2010). Prenatal paracetamol exposure and asthma: further evidence against confounding. Int J Epidemiol vol. 39, (3) 790-794.
10.1093/ije/dyq049
Bakolis I, Hooper R, Thompson RL, Shaheen SO(2010). Dietary patterns and adult asthma: population-based case-control study. Allergy vol. 65, (5) 606-615.
10.1111/j.1398-9995.2009.02215.x
Minelli C, Granell R, Newson R, Rose-Zerilli MJ, Torrent M, Ring SM, Holloway JW, Shaheen SO et al.(2010). Glutathione-S-transferase genes and asthma phenotypes: a Human Genome Epidemiology (HuGE) systematic review and meta-analysis including unpublished data. Int J Epidemiol vol. 39, (2) 539-562.
10.1093/ije/dyp337
Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M, Zhao JH, Ramasamy A et al.(2010). Genome-wide association study identifies five loci associated with lung function. Nature Genetics vol. 42, (1) 36-44.
10.1038/ng.501
Shaheen SO, Adcock IM(2009). The developmental origins of asthma: does epigenetics hold the key?. Am J Respir Crit Care Med vol. 180, (8) 690-691.
10.1164/rccm.200906-0893ED
Rose-Zerilli MJ, Barton SJ, Henderson AJ, Shaheen SO, Holloway JW(2009). Copy-number variation genotyping of GSTT1 and GSTM1 gene deletions by real-time PCR. Clin Chem vol. 55, (9) 1680-1685.
10.1373/clinchem.2008.120105
Shaheen SO, Northstone K, Newson RB, Emmett PM, Sherriff A, Henderson AJ(2009). Dietary patterns in pregnancy and respiratory and atopic outcomes in childhood. Thorax vol. 64, (5) 411-417.
10.1136/thx.2008.104703
Henderson J, Granell R, Heron J, Sherriff A, Simpson A, Woodcock A, Strachan DP, Shaheen SO et al.(2008). Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood. Thorax vol. 63, (11) 974-980.
10.1136/thx.2007.093187
Shaheen SO, Cullinan P(2008). Peanuts in pregnancy: what is a mother to do?. Am J Respir Crit Care Med vol. 178, (2) 113-114.
10.1164/rccm.200804-546ED
Shaheen SO(2008). Prenatal nutrition and asthma: hope or hype?. Thorax vol. 63, (6) 483-485.
10.1136/thx.2007.090019
Shaheen SO(2008). Vitamin D deficiency and the asthma epidemic. Thorax vol. 63, (3)
10.1136/thx.2007.091728
Okoko BJ, Burney PG, Newson RB, Potts JF, Shaheen SO(2007). Childhood asthma and fruit consumption. Eur Respir J vol. 29, (6) 1161-1168.
10.1183/09031936.00097806
Shaheen SO, Newson RB, Rayman MP, Wong AP-L, Tumilty MK, Phillips JM, Potts JF, Kelly FJ et al.(2007). Randomised, double blind, placebo-controlled trial of selenium supplementation in adult asthma. Thorax vol. 62, (6) 483-490.
10.1136/thx.2006.071563
Shaheen SO, Hines M, Newson RB, Wheeler M, Herrick DRM, Strachan DP, Jones RW, Burney PGJ et al.(2007). Maternal testosterone in pregnancy and atopic outcomes in childhood. Allergy vol. 62, (1) 25-32.
10.1111/j.1398-9995.2006.01240.x
Garcia V, Arts ICW, Sterne JAC, Thompson RL, Shaheen SO(2005). Dietary intake of flavonoids and asthma in adults. Eur Respir J vol. 26, (3) 449-452.
10.1183/09031936.05.00142104
Shaheen SO, Newson RB, Henderson AJ, Headley JE, Stratton FD, Jones RW, Strachan DP, ALSPAC Study Team(2005). Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood. Clin Exp Allergy vol. 35, (1) 18-25.
10.1111/j.1365-2222.2005.02151.x
Newson RB, Shaheen SO, Henderson AJ, Emmett PM, Sherriff A, Calder PC(2004). Umbilical cord and maternal blood red cell fatty acids and early childhood wheezing and eczema. J Allergy Clin Immunol vol. 114, (3) 531-537.
10.1016/j.jaci.2004.05.010
Shaheen SO, Newson RB, Henderson AJ, Emmett PM, Sherriff A, Cooke M, ALSPAC Study Team(2004). Umbilical cord trace elements and minerals and risk of early childhood wheezing and eczema. Eur Respir J vol. 24, (2) 292-297.
10.1183/09031936.04.00117803
Shaheen SO, Newson RB, Sherriff A, Henderson AJ, Heron JE, Burney PGJ, Golding J, ALSPAC Study Team(2002). Paracetamol use in pregnancy and wheezing in early childhood. Thorax vol. 57, (11) 958-963.
10.1136/thorax.57.11.958
Shaheen SO, Sterne JA, Thompson RL, Songhurst CE, Margetts BM, Burney PG(2001). Dietary antioxidants and asthma in adults: population-based case-control study. Am J Respir Crit Care Med vol. 164, (10 Pt 1) 1823-1828.
10.1164/ajrccm.164.10.2104061
Newson RB, Shaheen SO, Chinn S, Burney PG(2000). Paracetamol sales and atopic disease in children and adults: an ecological analysis. Eur Respir J vol. 16, (5) 817-823.
10.1183/09031936.00.16581700
Aaby P, Shaheen SO, Heyes CB, Goudiaby A, Hall AJ, Shiell AW, Jensen H, Marchant A(2000). Early BCG vaccination and reduction in atopy in Guinea-Bissau. Clin Exp Allergy vol. 30, (5) 644-650.
10.1046/j.1365-2222.2000.00803.x
Shaheen SO, Sterne JA, Songhurst CE, Burney PG(2000). Frequent paracetamol use and asthma in adults. Thorax vol. 55, (4) 266-270.
10.1136/thorax.55.4.266
Shaheen SO, Sterne JA, Montgomery SM, Azima H(1999). Birth weight, body mass index and asthma in young adults. Thorax vol. 54, (5) 396-402.
10.1136/thx.54.5.396
Shaheen SO(1999). Obesity and asthma: cause for concern?. Clin Exp Allergy vol. 29, (3) 291-293.
10.1046/j.1365-2222.1999.00516.x
Shaheen SO, Sterne JA, Tucker JS, Florey CD(1998). Birth weight, childhood lower respiratory tract infection, and adult lung function. Thorax vol. 53, (7) 549-553.
10.1136/thx.53.7.549
Stein CE, Kumaran K, Fall CH, Shaheen SO, Osmond C, Barker DJ(1997). Relation of fetal growth to adult lung function in south India. Thorax vol. 52, (10) 895-899.
10.1136/thx.52.10.895
Shaheen SO, Aaby P, Hall AJ, Barker DJ, Heyes CB, Shiell AW, Goudiaby A(1996). Cell mediated immunity after measles in Guinea-Bissau: historical cohort study. BMJ vol. 313, (7063) 969-974.
10.1136/bmj.313.7063.969
Shaheen SO, Aaby P, Hall AJ, Barker DJ, Heyes CB, Shiell AW, Goudiaby A(1996). Measles and atopy in Guinea-Bissau. Lancet vol. 347, (9018) 1792-1796.
10.1016/s0140-6736(96)91617-7
Shaheen SO(1995). Changing patterns of childhood infection and the rise in allergic disease. Clin Exp Allergy vol. 25, (11) 1034-1037.
10.1111/j.1365-2222.1995.tb03248.x
Shaheen SO, Barker DJ, Holgate ST(1995). Do lower respiratory tract infections in early childhood cause chronic obstructive pulmonary disease?. Am J Respir Crit Care Med vol. 151, (5) 1649-1651.
10.1164/ajrccm/151.5_Pt_1.1649
Shaheen SO, Barker DJ, Shiell AW, Crocker FJ, Wield GA, Holgate ST(1994). The relationship between pneumonia in early childhood and impaired lung function in late adult life. Am J Respir Crit Care Med vol. 149, (3 Pt 1) 616-619.
10.1164/ajrccm.149.3.8118627
Barker DJ, Godfrey KM, Fall C, Osmond C, Winter PD, Shaheen SO(1991). Relation of birth weight and childhood respiratory infection to adult lung function and death from chronic obstructive airways disease. BMJ vol. 303, (6804) 671-675.
10.1136/bmj.303.6804.671
Shaheen SO, Ellis FG(1983). Actinomycosis of the larynx. J R Soc Med vol. 76, (3) 226-228.
10.1177/014107688307600317
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