Publications: Dr Ewan Main
Perez-Riba A, Lowe A, MAIN E et al.(2018).
Context-dependent energetics of loop extensions in a family of tandem-repeat proteins. Biophysical Journal
Harvey JA, Itzhaki LS, Main ERG(2018).
Programmed Protein Self-Assembly Driven by Genetically Encoded Intein-Mediated Native Chemical Ligation. ACS Synth Biol
vol. 7,
(4)
1067-1074.
Lowe AR, Perez-Riba A, Itzhaki LS et al.(2018).
PyFolding: Open-Source Graphing, Simulation, and Analysis of the Biophysical Properties of Proteins. Biophysical Journal
Perez-Riba A, Lowe A, Main E et al. (2017).
Entropically-Challenged Tandem-repeat Proteins: Breakdown of Nearest-Neighbour Cooperativity. PROTEIN SCIENCE.
vol. 26,
108-108.
Millership C, Phillips JJ, Main ERG(2016).
Ising Model Reprogramming of a Repeat Protein's Equilibrium Unfolding Pathway. Journal of Molecular Biology
vol. 428,
(9 Pt A)
1804-1817.
Perez-Riba A, Main ER, Itzhaki LS (2016).
The Effect of Loop Insertions on the Folding of Tandem-Repeat Proteins. BIOPHYSICAL JOURNAL.
vol. 110,
181A-181A.
Rowling PJE, Sivertsson EM, Perez-Riba A et al.(2015).
Dissecting and reprogramming the folding and assembly of tandem-repeat proteins. Biochem Soc Trans
vol. 43,
(5)
881-888.
Main ERG, Phillips JJ, Millership C(2013).
Repeat protein engineering: creating functional nanostructures/biomaterials from modular building blocks. Biochem Soc Trans
vol. 41,
(5)
1152-1158.
Singh SK, Boyle AL, Main ERG(2013).
LcrH, a class II chaperone from the type three secretion system, has a highly flexible native structure. J Biol Chem
vol. 288,
(6)
4048-4055.
Phillips JJ, Millership C, Main ERG(2012).
Fibrous nanostructures from the self-assembly of designed repeat protein modules. Angew Chem Int Ed Engl
vol. 51,
(52)
13132-13135.
Phillips JJ, Javadi Y, Millership C et al.(2012).
Modulation of the multistate folding of designed TPR proteins through intrinsic and extrinsic factors. Protein Sci
vol. 21,
(3)
327-338.
Mahendrarajah K, Dalby PA, Wilkinson B et al.(2011).
A high-throughput fluorescence chemical denaturation assay as a general screen for protein-ligand binding. Anal Biochem
vol. 411,
(1)
155-157.
Boyd LK, Mercer B, Thompson D et al.(2010).
Characterisation of the SUMO-like domains of Schizosaccharomyces pombe Rad60. PLoS One
vol. 5,
(9)
Gaudet M, Remtulla N, Jackson SE et al.(2010).
Protein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scale. PROTEIN SCI
vol. 19,
(8)
1544-1554.
Javadi Y, Main ERG(2009).
Exploring the folding energy landscape of a series of designed consensus tetratricopeptide repeat proteins. P NATL ACAD SCI USA
vol. 106,
(41)
17383-17388.
Main ERG, Lowe AR, Mochrie SGJ et al.(2005).
A recurring theme in protein engineering: the design, stability and folding of repeat proteins. CURR OPIN STRUC BIOL
vol. 15,
(4)
464-471.
Kajander T, Cortajarena AL, Main ERG et al.(2005).
A new folding paradigm for repeat proteins. J AM CHEM SOC
vol. 127,
(29)
10188-10190.
Main ERG, Stott K, Jackson SE et al.(2005).
Local and long-range stability in tandemly arrayed tetratricopeptide repeats. P NATL ACAD SCI USA
vol. 102,
(16)
5721-5726.
Maxwell KL, Wildes D, Zarrine-Afsar A et al.(2005).
Protein folding: Defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins. PROTEIN SCI
vol. 14,
(3)
602-616.
Main ERG, Jackson SE, Regan L(2003).
The folding and design of repeat proteins: reaching a consensus. CURR OPIN STRUC BIOL
vol. 13,
(4)
482-489.
Main ERG, Xiong Y, Cocco MJ et al.(2003).
Design of stable alpha-helical arrays from an idealized TPR motif. STRUCTURE
vol. 11,
(5)
497-508.
Main ERG, Fulton KF, Daggett V et al.(2001).
A comparison of experimental and computational methods for mapping the interactions present in the transition state for folding of FKBP12. J BIOL PHYS
vol. 27,
(2)
99-117.
Main ERG, Jackson SE(1999).
Does trifluoroethanol affect folding pathways and can it be used as a probe of structure in transition states?. NAT STRUCT BIOL
vol. 6,
(9)
831-835.
Main ERG, Fulton KF, Jackson SE(1999).
Folding pathway of FKBP12 and characterisation of the transition state. J MOL BIOL
vol. 291,
(2)
429-444.
Fulton KF, Main ERG, Daggett V et al.(1999).
Mapping the interactions present in the transition state for unfolding/folding of FKBP12. J MOL BIOL
vol. 291,
(2)
445-461.
Main ERG, Fulton KF, Jackson SE(1998).
Context-dependent nature of destabilizing mutations on the stability of FKBP12. BIOCHEMISTRY-US
vol. 37,
(17)
6145-6153.
