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Publications:  Dr Michael Barnes

John CR, Watson D, Barnes MR, Pitzalis C, Lewis MJ(2020). Spectrum: Fast density-aware spectral clustering for single and multi-omic data. Bioinformatics vol. 36, (4) 1159-1166.
John CR, Watson D, Russ D, Goldmann K, Ehrenstein M, Pitzalis C, Lewis M, Barnes M(2020). M3C: Monte Carlo reference-based consensus clustering. Scientific Reports vol. 10, (1)
Lewis MJ, Barnes MR, Blighe K, Goldmann K, Rana S, Hackney JA, Ramamoorthi N, John CR et al.(2019). Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes. Cell Reports vol. 28, 2455-2470.
Cabrera CP, Ng F, Nicholls HL, Gupta A, Barnes MR, Munroe PB, Caulfield MJ(2019). Over 1000 genetic loci influencing blood pressure with multiple systems and tissues implicated. Human Molecular Genetics vol. 28, (R2) R151-R161.
Mancini A, Howard SR, Cabrera CP, Barnes MR, David A, Wehkalampi K, Heger S, Lomniczi A et al.(2019). EAP1 regulation of GnRH promoter activity is important for human pubertal timing. Human Molecular Genetics vol. 28, (8) 1357-1368.
Bodagh N, Archbold RA, Weerackody R, Hawking MKD, Barnes MR, Lee AM, Janjuha S, Gutteridge C et al.(2019). Feasibility of real-time capture of routine clinical data in the electronic health record: a hospital-based, observational service-evaluation study. BMJ Open vol. 8, (3) e019790-e019790.
Foulkes AC, Watson DS, Carr DF, Kenny JG, Slidel T, Parslew R, Pirmohamed M, PSORT Consortium et al.(2019). A Framework for Multi-Omic Prediction of Treatment Response to Biologic Therapy for Psoriasis. J Invest Dermatol vol. 139, (1) 100-107.
Watson DS, Krutzinna J, Bruce IN, Griffiths CEM, McInnes IB, Barnes MR, Floridi L(2019). Clinical applications of machine learning algorithms: Beyond the black box. BMJ (Online) vol. 364,
Cope AP, Barnes MR, Belson A, Binks M, Brockbank S, Bonachela-Capdevila F, Carini C, Fisher BA et al.(2018). The RA-MAP Consortium: a working model for academia-industry collaboration. Nat Rev Rheumatol vol. 14, (1) 53-60.
Cherlin S, Plant D, Taylor JC, Colombo M, Spiliopoulou A, Tzanis E, Morgan AW, Barnes MR et al.(2018). Prediction of treatment response in rheumatoid arthritis patients using genome-wide SNP data. Genetic Epidemiology vol. 42, (8) 754-771.
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N et al.(2018). Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet vol. 50, (12) 1755-1755.
Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB et al.(2018). Correction: Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Med vol. 15, (10) e1002694-e1002694.
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N et al.(2018). Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics vol. 50, (10) 1412-1425.
Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, S. Watson D, Barnes MR et al.(2018). Sex differences in the nitrate-nitrite-NO <sup>•</sup> pathway: Role of oral nitrate-reducing bacteria. Free Radical Biology and Medicine vol. 126, 113-121.
Howard SR, Oleari R, Poliandri A, Chantzara V, Fantin A, Ruiz-Babot G, Metherell LA, Cabrera CP et al.(2018). HS6ST1 Insufficiency Causes Self-Limited Delayed Puberty in Contrast with Other GnRH Deficiency Genes. Journal of Clinical Endocrinology and Metabolism vol. 103, (9) 3420-3429.
Tragante V, Hemerich D, Alshabeeb M, Brænne I, Lempiäinen H, Patel RS, den Ruijter HM, Barnes MR et al.(2018). Druggability of Coronary Artery Disease Risk Loci. Circ Genom Precis Med vol. 11, (8) e001977-e001977.
Taylor JC, Bongartz T, Massey J, Mifsud B, Spiliopoulou A, Scott IC, Wang J, Morgan M et al.(2018). Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients. Pharmacogenomics Journal vol. 18, (4) 528-538.
Lewis MJ, Barnes MR(2018). RNA sequencing and machine learning as molecular scalpels. Nat Rev Rheumatol vol. 14, (7) 388-390.
Foulkes AC, Watson DS, Barnes MR(2018). Bioinformatics for dermatology: why we should learn about code. Br J Dermatol vol. 178, (4) 984-984.
Howard SR, Guasti L, Poliandri A, David A, Cabrera CP, Barnes MR, Wehkalampi K, O'Rahilly S et al.(2018). Contributions of function-Altering variants in genes implicated in pubertal timing and body mass for self-limited delayed puberty. Journal of Clinical Endocrinology and Metabolism vol. 103, (2) 649-659.
Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, Manning AK, Grarup N et al.(2017). New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circulation: Cardiovascular Genetics vol. 10, (5)
CABRERA CP, MANSON J, SHEPHERD JM, TORRANCE HD, WATSON D, LONGHI MP, HOTI M, PATEL MB et al.(2017). Signatures of Inflammation and Impending Multiple Organ Dysfunction in the Hyperacute Phase of Trauma. PLoS Medicine
Sordi R, Nandra KK, Chiazza F, Johnson FL, Cabrera CP, Torrance HD, Yamada N, Patel NSA et al.(2017). Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation. Ann Surg vol. 265, (2) 408-417.
Cabrera CP, Manson J, Shepherd JM, Torrance HD, Watson D, Longhi MP, Hoti M, Patel MB et al.(2017). Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study. PLoS Medicine vol. 14, (7)
Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P et al.(2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet vol. 49, (3) 403-415.
Shaked A, Chang BL, Barnes MR, Sayre P, Li YR, Asare S, DesMarais M, Holmes MV et al.(2017). An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection. Hepatology vol. 65, (1) 269-280.
Gagliano SA, Pouget JG, Hardy J, Knight J, Barnes MR, Ryten M, Weale ME(2016). Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases. Annals of Clinical and Translational Neurology vol. 3, (12) 924-933.
Gagliano SA, Pouget JG, Hardy J, Barnes MR, Knight J, Ryten M, Weale ME (2016). Genetic Variability in Both the Adaptive and Innate Immune Systems Contribute to Alzheimer's and Parkinson's Disease Risk. GENETIC EPIDEMIOLOGY. vol. 40, 637-637.
Hosking A, Koulouroudias M, Zemrak F, Moon JC, Rossi A, Lee A, Barnes MR, Boubertakh R et al.(2016). Evaluation of splenic switch off in a tertiary imaging centre: validation and assessment of utility. European Heart Journal Cardiovascular Imaging
Smit RA, Postmus I, Trompet S, Barnes MR, Warren H, Arsenault BJ, Chasman DI, Cupples LA et al.(2016). Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment. Pharmacogenomics vol. 17, (15) 1621-1628.
MUNROE PB(2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics
Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE et al.(2016). Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. Journal of Medical Genetics
Foulkes AC, Watson DS, Rattray NJ, Donaldson M, Goodacre R, Reynolds N, Griffiths CE, Warren RB et al. (2016). Systems biology approach to the analysis of pharmacogenomic data in psoriasis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 136, S167-S167.
Broad J, Maurel D, Kung VWS, Hicks GA, Schemann M, Barnes MR, Kenakin TP, Granier S et al.(2016). Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design. Scientific Reports vol. 6,
Jia Z, Liu Y, Guan N, Bo X, Luo Z, Barnes MR(2016). Cogena, a novel tool for co-expressed gene-set enrichment analysis, applied to drug repositioning and drug mode of action discovery. BMC Genomics vol. 17, (1)
Narasimhan VM, Hunt KA, Mason D, Baker CL, Karczewski KJ, Barnes MR, Barnett AH, Bates C et al.(2016). Health and population effects of rare gene knockouts in adult humans with related parents. Science vol. 352, (6284) 474-477.
HOWARD SR, Guasti L, Ruiz-Babot G, Mancini A, David A, Storr H, Metherell LA, Sternberg MJE et al.(2016). IGSF10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty. EMBO Molecular Medicine vol. 8, (6) 626-42.
Tragante V, Braenne I, Moore JH, Barnes MR, Erdmann J, Asselbergs FW(2016). Evaluating CAD/MI loci as targets for prevention of myocardial infarction. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION vol. 46, 20-21.
Rucker JJH, Tansey KE, Rivera M, Pinto D, Cohen-Woods S, Uher R, Aitchison KJ, Craddock N et al.(2016). Phenotypic association analyses with copy number variation in recurrent depressive disorder. Biological Psychiatry vol. 79, (4) 329-336.
Mancini A, Howard SR, Ruiz-Babot G, Cabrera CP, Barnes MR, Guasti L, Dunkel L (2016). LGR4 and EAP1 Mutations are Implicated in the Phenotype of Self-limited Delayed Puberty. HORMONE RESEARCH IN PAEDIATRICS. vol. 86, 58-58.
Rodriguez S, Gaunt TR, Guo Y, Zheng J, Barnes MR, Tang W, Danish F, Johnson A et al.(2016). Lipids, obesity and gallbladder disease in women: Insights from genetic studies using the cardiovascular gene-centric 50K SNP array. European Journal of Human Genetics vol. 24, (1) 106-112.
Griffiths CEM, Barnes MR, Burden AD, Nestle FO, Reynolds NJ, Smith CH, Warren RB, Barker JNWN(2015). Establishing an academic-industrial stratified medicine consortium: Psoriasis stratification to optimize relevant therapy. Journal of Investigative Dermatology vol. 135, (12) 2903-2907.
Owen HC, Torrance H, Barnes MR, Brohi K, Knight JC, Hinds CJ, O'Dwyer MJ(2015). The Role of Micrornas in The Development of Hospital Acquired Infection in Polytrauma Patients. Intensive Care Med Exp vol. 3, (Suppl 1)
Gagliano SA, Ravji R, Barnes MR, Weale ME, Knight J (2015). A Methods Comparison: In silico prioritization of genetic risk variants using functional genomic information. GENETIC EPIDEMIOLOGY. vol. 39, 549-550.
Kokkinopoulos I, Ishida H, Saba R, Ruchaya P, Cabrera C, Struebig M, Barnes M, Terry A et al.(2015). Single-cell expression profiling reveals a dynamic state of cardiac precursor cells in the early mouse embryo. PLoS ONE vol. 10, (10)
Jia Z, Zhang X, Guan N, Bo X, Barnes MR, Luo Z(2015). Gene ranking of RNA-seq data via discriminant non-negative matrix factorization. PLoS ONE vol. 10, (9)
Lanktree MB, Elbers CC, Li Y, Zhang G, Duan Q, Karczewski KJ, Guo Y, Tragante V et al.(2015). Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration. Journal of Lipid Research vol. 56, (9) 1781-1786.
Gagliano SA, Ravji R, Barnes MR, Weale ME, Knight J(2015). Smoking gun or circumstantial evidence? Comparison of statistical learning methods using functional annotations for prioritizing risk variants. Scientific Reports vol. 5,
Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, De Geus EJC, Hemani G et al.(2015). The association between lower educational attainment and depression owing to shared genetic effects? Results in ∼25 000 subjects. Molecular Psychiatry vol. 20, (6) 735-743.
O'Dushlaine C, Rossin L, Lee PH, Duncan L, Parikshak NN, Newhouse S, Ripke S, Neale BM et al.(2015). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. NATURE NEUROSCIENCE vol. 18, (2) 199-209.
Cabrera CP, Ng FL, Warren HR, Barnes MR, Munroe PB, Caulfield MJ(2015). Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics. Wiley Interdisciplinary Reviews: Systems Biology and Medicine vol. 7, (2) 73-90.
Taylor PN, Porcu E, Chew S, Campbell PJ, Traglia M, Brown SJ, Mullin BH, Shihab HA et al.(2015). Whole-genome sequence-based analysis of thyroid function. Nature Communications vol. 6,
Foulkes AC, Rattray NJW, Correa E, Trivedi DK, Al-Sharqi A, Parslew R, Barnes M, Goodacre R et al. (2014). Modulation of metabolomic signature on biological treatment with etanercept in psoriasis. BRITISH JOURNAL OF DERMATOLOGY. vol. 171, E169-E169.
Foulkes AC, Carr DF, Al-Sharqi A, Parslew R, Pirmohamed M, Reynolds NJ, Donaldson M, Barnes M et al. (2014). Pharmacogenomic signatures of response to etanercept therapy for psoriasis. BRITISH JOURNAL OF DERMATOLOGY. vol. 171, E114-E115.
Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K et al.(2014). Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun vol. 5,
Trompet S, Postmus I, Deshmukh HA, Barnes MR, Psaty BM, Tardif JC, Hitman G, Krauss RM et al. (2014). Pharmacogenetic GWAS meta-analysis of LDL cholesterol response to statins. EUROPEAN HEART JOURNAL. vol. 35, 370-370.
Marsh S, Martins V, Caley M, Barnes M, Donaldson M, O'toole E (2014). RNA-Seqing the skin basement membrane. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 134, S25-S25.
Marino S, Ricci B, Greco A, Acquati S(2014). A novel polycomb feed forward loop in glioblastoma multiforme. Neuro Oncol vol. 16 Suppl 3,
Gagliano SA, Barnes MR, Weale ME, Knight J(2014). A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization. PLoS ONE vol. 9, (5)
Yoneyama S, Guo Y, Lanktree MB, Barnes MR, Elbers CC, Karczewski KJ, Padmanabhan S, Bauer F et al.(2014). Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. HUMAN MOLECULAR GENETICS vol. 23, (9) 2498-2510.
Marsh S, Martins V, Caley M, Barnes M, Donaldson M, O'Toole E (2014). Global transcriptomic changes in primary keratinocytes with loss of basement membrane genes. BRITISH JOURNAL OF DERMATOLOGY. vol. 170, E37-E38.
Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T et al.(2014). Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Am J Hum Genet vol. 94, (3) 349-360.
Voros S, Maurovich-Horvat P, Marvasty IB, Bansal AT, Barnes MR, Vazquez G, Murray SS, Voros V et al.(2014). Precision phenotyping, panomics, and system-level bioinformatics to delineate complex biologies of atherosclerosis: Rationale and design of the "Genetic Loci and the Burden of Atherosclerotic Lesions" study. Journal of Cardiovascular Computed Tomography vol. 8, (6) 442-451.
Sanseau P, Agarwal P, Barnes MR, Pastinen T, Richards JB, Cardon LR, Mooser V(2013). Rational drug repositioning by medical genetics Reply. NATURE BIOTECHNOLOGY vol. 31, (12) 1082-1082.
Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ et al.(2013). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet vol. 45, (9) 984-994.
Best LG, Saxena R, Anderson CM, Barnes MR, Hakonarson H, Falcon G, Martin C, Castillo BA et al.(2013). Two Variants of the C-Reactive Protein Gene Are Associated with Risk of Pre-Eclampsia in an American Indian Population. PLOS ONE vol. 8, (8) Article ARTN e71231,
Munroe PB, Barnes MR, Caulfield MJ(2013). Advances in blood pressure genomics. Circ Res vol. 112, (10) 1365-1379.
Sullivan PF, Daly MJ, Ripke S, Lewis CM, Lin D-Y, Wray NR, Neale B, Levinson DF et al.(2013). A mega-analysis of genome-wide association studies for major depressive disorder. MOLECULAR PSYCHIATRY vol. 18, (4) 497-511.
Rucker JJH, Breen G, Pinto D, Pedroso I, Lewis CM, Cohen-Woods S, Uher R, Schosser A et al.(2013). Genome-wide association analysis of copy number variation in recurrent depressive disorder. MOLECULAR PSYCHIATRY vol. 18, (2) 183-189.
Pedroso I, Lourdusamy A, Rietschel M, Noethen MM, Cichon S, McGuffin P, Al-Chalabi A, Barnes MR et al.(2012). Common Genetic Variants and Gene-Expression Changes Associated with Bipolar Disorder Are Over-Represented in Brain Signaling Pathway Genes. BIOLOGICAL PSYCHIATRY vol. 72, (4) 311-317.
Sanseau P, Agarwal P, Barnes MR, Pastinen T, Richards JB, Cardon LR, Mooser V(2012). Use of genome-wide association studies for drug repositioning. NATURE BIOTECHNOLOGY vol. 30, (4) 317-320.
Barnes MR(2012). An Open Innovation Ecosystem for Drug Discovery. MEDCHEMCOMM vol. 3, (1) MCW92-MCW97.
Jugurnauth SK, Chen CK, Barnes MR, Li T, Lin SK, Liu HC, Collier DA, Breen G(2011). A COMT gene haplotype associated with methamphetamine abuse. Pharmacogenetics and Genomics vol. 21, (11) 731-740.
Barnes MR, Huxley-Jones J, Maycox PR, Lennon M, Thornber A, Kelly F, Bates S, Taylor A et al.(2011). Transcription and Pathway Analysis of the Superior Temporal Cortex and Anterior Prefrontal Cortex in Schizophrenia. JOURNAL OF NEUROSCIENCE RESEARCH vol. 89, (8) 1218-1227.
Xu C-F, Reck BH, Goodman VL, Xue Z, Huang L, Barnes MR, Koshy B, Spraggs CF et al.(2011). Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma. JOURNAL OF HEPATOLOGY vol. 54, (6) 1237-1243.
Knight J, Barnes MR, Breen G, Weale ME(2011). Using functional annotation for the Empirical determination of Bayes factors for genome-wide association study analysis. PLoS ONE vol. 6, (4)
Dow DJ, Huxley-Jones J, Hall JM, Francks C, Maycox PR, Kew JNC, Gloger IS, Mehta NAL et al.(2011). ADAMTSL3 as a candidate gene for schizophrenia: Gene sequencing and ultra-high density association analysis by imputation. SCHIZOPHRENIA RESEARCH vol. 127, (1-3) 28-34.
Lewis CM, Ng MY, Butler AW, Cohen-Woods S, Uher R, Pirlo K, Weale ME, Schosser A et al.(2010). Genome-Wide Association Study of Major Recurrent Depression in the UK Population. AM J PSYCHIAT vol. 167, (8) 949-957.
Uher R, Perroud N, Ng MYM, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A et al.(2010). Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project. AMERICAN JOURNAL OF PSYCHIATRY vol. 167, (5) 555-564.
Barnes MR, Breen G(2010). A short primer on the functional analysis of copy number variation for biomedical scientists. Methods Mol Biol vol. 628, 119-135.
Barnes MR(2010). Exploring the landscape of the genome. Methods Mol Biol vol. 628, 21-38.
Barnes MR(2010). Genetic variation analysis for biomedical researchers: a primer. Methods Mol Biol vol. 628, 1-20.
Maycox PR, Kelly F, Taylor A, Bates S, Reid J, Logendra R, Barnes MR, Larminie C et al.(2009). Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function. MOLECULAR PSYCHIATRY vol. 14, (12) 1083-1094.
Knight J, Barnes MR, Breen G, Weale ME (2009). Functional annotation of GWAS hits. GENETIC EPIDEMIOLOGY. vol. 33, 787-788.
Barnes MR, Harland L, Foord SM, Hall MD, Dix I, Thomas S, Williams-Jones BI, Brouwer CR(2009). Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery. Nat Rev Drug Discov vol. 8, (9) 701-708.
Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D, Wu W, Uitdehaag BMJ et al.(2009). Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. HUMAN MOLECULAR GENETICS vol. 18, (11) 2078-2090.
Rujescu D, Ingason A, Cichon S, Pietilainen OPH, Barnes MR, Toulopoulou T, Picchioni M, Vassos E et al.(2009). Disruption of the neurexin 1 gene is associated with schizophrenia. HUMAN MOLECULAR GENETICS vol. 18, (5) 988-996.
Huxley-Jones J, Foord SM, Barnes MR(2009). Drug discovery in the extracellular matrix. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY vol. 90, (1) A80-A81.
Huxley-Jones J, Foord SM, Barnes MR(2008). Drug discovery in the extracellular matrix. Drug Discov Today vol. 13, (15-16) 685-694.
Bansal AT, Barnes MR(2008). Genomics in drug discovery: The best things come to those who wait. CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT vol. 11, (3) 303-310.
Pettersson F, Morris AP, Barnes MR, Cardon LR(2008). Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies. BMC BIOINFORMATICS vol. 9, Article ARTN 138,
Li H, Wetten S, Li L, St Jean PL, Upmanyu R, Surh L, Hosford D, Barnes MR et al.(2008). Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol vol. 65, (1) 45-53.
Zhu G, Carlsen K, Carlsen K-H, Lenney W, Silverman M, Whyte MK, Hosking L, Helms P et al.(2008). Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations. GENES AND IMMUNITY vol. 9, (1) 23-29.
Barnes MR, Deharo S, Grocock RJ, Brown JR, Sanseau P(2007). The micro RNA target paradigm: a fundamental and polymorphic control layer of cellular expression. EXPERT OPINION ON BIOLOGICAL THERAPY vol. 7, (9) 1387-1399.
Pettersson F, Morris AP, Derwent PS, Barnes MR, Cardon LR (2007). GOLDsurfer2: A comprehensive tool for the analysis and visualization of whole genome association studies. GENETIC EPIDEMIOLOGY. vol. 31, 494-494.
Southan C, Ulvsbäck M, Barnes MR(2007). A Bioinformatics Perspective on Genetics in Drug Discovery and Development. 495-528.
Barnes MR(2007). Bioinformatics Challenges for the Geneticist. 1-16.
Barnes MR(2007). Bioinformatics for Geneticists: A Bioinformatics Primer for the Analysis of Genetic Data: Second Edition. Bioinformatics for Geneticists: A Bioinformatics Primer for the Analysis of Genetic Data: Second Edition1-554.
Southan C, Barnes MR(2007). Finding, Delineating and Analysing Genes. 85-104.
Barnes MR(2007). Integrating Genetics, Genomics and Epigenomics to Identify Disease Genes. 185-215.
Barnes MR, Derwent PS(2007). Needle in a Haystack? Dealing with 500 000 SNP Genome Scans. 447-493.
Brown JR, Deharo S, Dancis B, Barnes MR, Sanseau P(2007). Non-Coding RNA Bioinformatics. 343-368.
Plumpton M, Barnes MR(2007). Predictive Functional Analysis of Polymorphisms: An Overview. 247-280.
Barnes MR(2007). Preface. Bioinformatics for Geneticists: A Bioinformatics Primer for the Analysis of Genetic Data: Second Edition
Barnes MR(2007). Bioinformatics for Geneticists. John Wiley & Sons
Teh MT, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM et al.(2007). Erratum: Role for WNT16B in human epidermal keratinocyte proliferation and differentiation (Journal of Cell Science vol. 120 (330-339)). Journal of Cell Science vol. 120, (5)
Teh MT, Blaydon D, Ghali LR, Edmunds S, Pantazi E, Barnes MR, Leigh IM, Kelsell DP et al.(2007). Role for WNT16B in human epidermal keratinocyte proliferation and differentiation. J CELL SCI vol. 120, (2) 330-339.
Philpott MP, Kelsell DP, Leigh IM, TEH M, Briggs V, Pantazi E, Edmunds S, Blaydon D et al.(2007). Role for WNT16B in Human Epidermal Keratinocyte Proliferation and Differentiation. Journal Cell Science vol. 120, (2) 330-339.
Barnes MR, Holbrook J, Feild JA, Searls DB, Sanseau P(2006). Risk in drug trials. LANCET vol. 368, (9554) 2205-2205.
Barnes MR(2006). Navigating the HapMap. Brief Bioinform vol. 7, (3) 211-224.
Common JEA, Bitner-Glindzicz M, O'Toole EA, Barnes MR, Jenkins L, Forge A, Kelsell DP(2005). Specific loss of connexin 26 expression in ductal sweat gland epithelium associated with the deletion mutation del(GJB6-D13S1830). CLIN EXP DERMATOL vol. 30, (6) 688-693.
Prabhakar U, Conway TM, Murdock P, Mooney JL, Clark S, Hedge P, Bond BC, Jazwinska EC et al.(2005). Correlation of protein and gene expression profiles of inflammatory proteins after endotoxin challenge in human subjects. DNA AND CELL BIOLOGY vol. 24, (7) 410-431.
Scott BB, Zaratin PF, Clarke GD, Barnes MR, Murdock PR, Lynch FJ, Duckworth M(2004). C20orf9-003 (ACI-1), a gene localized on chromosome 20q13.12 encoding for a 49 kD cytoplasmic protein with a putative nucleotide binding site. DNA SEQUENCE vol. 15, (1) 1-8.
Dow D, Devitt PJ, Candlin A, Gray IC, Barnes MR (2002). SNP Locator - A bioinformatics tool for determining the distance between SNPs as an aid to linkage disequilibrium mapping. JOURNAL OF MEDICAL GENETICS. vol. 39, S73-S73.
Barnes MR(2002). Psychiatric genetics in silico: databases and tools for psychiatric geneticists. PSYCHIATRIC GENETICS vol. 12, (2) 67-73.
Barnes MR(2002). SNP and mutation data on the Web - hidden treasures for uncovering. COMPARATIVE AND FUNCTIONAL GENOMICS vol. 3, (1) 67-74.
Hosking LK, Boyd PR, Xu CF, Nissum M, Cantone K, Purvis IJ, Khakhar R, Barnes MR et al.(2002). Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity. Pharmacogenomics J vol. 2, (3) 165-175.
McGinnis RE, Fox H, Yates P, Cameron LA, Barnes MR, Gray IC, Spurr NK, Hurko O et al.(2001). Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland. NATURE GENETICS vol. 28, (2) 128-129.
Fear MW, Kelsell DP, Spurr NK, Barnes MR(2000). Wnt-16a, a novel Wnt-16 isoform, which shows differential expression in adult human tissues. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS vol. 278, (3) 814-820.
James IE, Kumar S, Barnes MR, Gress CJ, Hand AT, Dodds RA, Connor JR, Bradley BR et al.(2000). FrzB-2: a human secreted frizzled-related protein with a potential role in chondrocyte apoptosis. OSTEOARTHRITIS AND CARTILAGE vol. 8, (6) 452-463.
Sims MA, Field SD, Barnes MR, Shaikh N, Ellington K, Murphy KE, Spurr N, Campbell DA(2000). Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51. CYTOGENETICS AND CELL GENETICS vol. 89, (3-4) 268-271.
Wilgoss A, Leigh IM, Barnes MR, Dopping-Hepenstal P, Eady RA, Walter JM, Kennedy CT, Kelsell DP(1999). Identification of a novel mutation R42P in the gap junction protein beta-3 associated with autosomal dominant erythrokeratoderma variabilis. J Invest Dermatol vol. 113, (6) 1119-1122.
Barnes MR, Russell RB(1999). A lipid-binding domain in Wnt: a case of mistaken identity?. CURRENT BIOLOGY vol. 9, (19) R717-R718.
Valdes AM, Bouzyk M, O'Brien E, Gale D, Panchal S, Barnes M, Ralston S, Reid D et al.(1999). Role of polymorphisms in parathyroid hormone receptor 1, transforming growth factor beta 1 and estrogen receptor in the genetics of osteoporosis. AMERICAN JOURNAL OF HUMAN GENETICS vol. 65, (4) A470-A470.
Valdes AM, Chamberlain JC, Bouzyk M, Panchal S, Gale D, Barnes M, Ralston SH, Reid DM et al.(1999). Genetics of osteoporosis: Association between ESR (11q12) and ERR1 (6q25) and bone mineral density and rate of change. JOURNAL OF BONE AND MINERAL RESEARCH vol. 14, S333-S333.
Barnes MR, Duckworth DM, Beeley LJ(1998). Frizzled proteins constitute a novel family of G protein-coupled receptors, most closely related to the secretin family. TRENDS IN PHARMACOLOGICAL SCIENCES vol. 19, (10) 399-400.
Hu ED, Zhu Y, Fredrickson T, Barnes M, Kelsell D, Beeley L, Brooks D(1998). Tissue restricted expression of two human Frzbs in preadipocytes and pancreas. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS vol. 247, (2) 287-293.
Duetz WA, Wind B, van Andel JG, Barnes MR, Williams PA, Rutgers M(1998). Biodegradation kinetics of toluene, m-xylene, p-xylene and their intermediates through the upper TOL pathway in Pseudomonas putida (pWW0). MICROBIOLOGY-SGM vol. 144, 1669-1675.
Barnes MR, Duetz WA, Williams PA(1997). A 3-(3-hydroxyphenyl)propionic acid catabolic pathway in Rhodococcus globerulus PWD1: Cloning and characterization of the hpp operon. JOURNAL OF BACTERIOLOGY vol. 179, (19) 6145-6153.
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