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Publications:  Dr Angus Cameron

Murray ER, Cameron AJM(2017). Towards specific inhibition of mTORC2. Aging (Albany NY) vol. 9, (12) 2461-2462.
10.18632/aging.101346
Hurst CD, Alder O, Platt FM, Droop A, Stead LF, Burns JE, Burghel GJ, Jain S et al.(2017). Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency. Cancer Cell vol. 32, (5) 701-715.e7.
10.1016/j.ccell.2017.08.005
Cameron AJM, Veeriah S, Marshall JJT, Murray ER, Larijani B, Parker PJ(2017). Uncoupling TORC2 from AGC kinases inhibits tumour growth. Oncotarget vol. 8, (49) 84685-84696.
10.18632/oncotarget.20086
Cenciarelli C, Marei HE, Felsani A, Casalbore P, Sica G, Puglisi MA, Cameron AJM, Olivi A et al.(2016). PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals. Oncotarget
10.18632/oncotarget.10132
Quétier I, Marshall JJT, Spencer-Dene B, Lachmann S, Casamassima A, Franco C, Escuin S, Worrall JT et al.(2016). Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion. Cell Rep vol. 14, (3) 440-448.
10.1016/j.celrep.2015.12.049
Martin-Liberal J, Cameron AJ, Claus J, Judson IR, Parker PJ, Linch M(2014). Targeting protein kinase C in sarcoma. Biochimica et Biophysica Acta - Reviews on Cancer vol. 1846, (2) 547-559.
10.1016/j.bbcan.2014.10.002
Linch M, Riou P, Claus J, Cameron AJ, de Naurois J, Larijani B, Ng T, McDonald NQ et al.(2014). Functional implications of assigned, assumed and assembled PKC structures. Biochem Soc Trans vol. 42, (1) 35-41.
10.1042/BST20130192
Linch M, Sanz-Garcia M, Rosse C, Riou P, Peel N, Madsen CD, Sahai E, Downward J et al.(2014). Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. Carcinogenesis vol. 35, (2) 396-406.
10.1093/carcin/bgt313
Linch M, Sanz-Garcia M, Soriano E, Zhang Y, Riou P, Rosse C, Cameron A, Knowles P et al.(2013). A cancer-associated mutation in atypical protein kinase Cι occurs in a substrate-specific recruitment motif. Sci Signal vol. 6, (293)
10.1126/scisignal.2004068
Claus J, Cameron AJM, Parker PJ(2013). Pseudokinase drug intervention: a potentially poisoned chalice. Biochem Soc Trans vol. 41, (4) 1083-1088.
10.1042/BST20130078
Cameron AJM, Linch MD, Saurin AT, Escribano C, Parker PJ(2011). mTORC2 targets AGC kinases through Sin1-dependent recruitment. Biochem J vol. 439, (2) 287-297.
10.1042/BJ20110678
Cameron AJM(2011). Occupational hazards: allosteric regulation of protein kinases through the nucleotide-binding pocket. Biochem Soc Trans vol. 39, (2) 472-476.
10.1042/BST0390472
Rosse C, Linch M, Kermorgant S, Cameron AJM, Boeckeler K, Parker PJ(2010). PKC and the control of localized signal dynamics. Nat Rev Mol Cell Biol vol. 11, (2) 103-112.
10.1038/nrm2847
Cameron AJM, Parker PJ(2010). Protein kinase C - a family of protein kinases, allosteric effectors or both?. Adv Enzyme Regul vol. 50, (1) 169-177.
10.1016/j.advenzreg.2009.10.004
Cameron AJM, Escribano C, Saurin AT, Kostelecky B, Parker PJ(2009). PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity. Nat Struct Mol Biol vol. 16, (6) 624-630.
10.1038/nsmb.1606
Cameron AJ, Procyk KJ, Leitges M, Parker PJ(2008). PKC alpha protein but not kinase activity is critical for glioma cell proliferation and survival. Int J Cancer vol. 123, (4) 769-779.
10.1002/ijc.23560
Saurin AT, Durgan J, Cameron AJ, Faisal A, Marber MS, Parker PJ(2008). The regulated assembly of a PKCepsilon complex controls the completion of cytokinesis. Nat Cell Biol vol. 10, (8) 891-901.
10.1038/ncb1749
Durgan J, Cameron AJ, Saurin AT, Hanrahan S, Totty N, Messing RO, Parker PJ(2008). The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily. Biochem J vol. 411, (2) 319-331.
10.1042/bj20071348
Cameron AJ, De Rycker M, Calleja V, Alcor D, Kjaer S, Kostelecky B, Saurin A, Faisal A et al.(2007). Protein kinases, from B to C. Biochem Soc Trans vol. 35, (Pt 5) 1013-1017.
10.1042/BST0351013
Hillyard DZ, Nutt CD, Thomson J, McDonald KJ, Wan RK, Cameron AJM, Mark PB, Jardine AG(2007). Statins inhibit NK cell cytotoxicity by membrane raft depletion rather than inhibition of isoprenylation. Atherosclerosis vol. 191, (2) 319-325.
10.1016/j.atherosclerosis.2006.05.037
Cameron AJ, De Rycker M, Calleja V, Alcor D, Kjaer S, Kostelecky B, Saurin A, Faisal A et al.(2007). Protein kinases, from B to C. Biochemical Society Transactions vol. 35, (5) 1013-1017.
10.1042/BST0351013
Hillyard DZ, Cameron AJM, McDonald KJ, Thomson J, MacIntyre A, Shiels PG, Panarelli M, Jardine AG(2004). Simvastatin inhibits lymphocyte function in normal subjects and patients with cardiovascular disease. Atherosclerosis vol. 175, (2) 305-313.
10.1016/j.atherosclerosis.2004.03.018
Hillyard DZ, Jardine AG, McDonald KJ, Cameron AJM(2004). Fluvastatin inhibits raft dependent Fcgamma receptor signalling in human monocytes. Atherosclerosis vol. 172, (2) 219-228.
10.1016/j.atherosclerosis.2003.11.004
Cameron AJM, McDonald KJ, Harnett MM, Allen JM(2002). Differentiation of the human monocyte cell line, U937, with dibutyryl cyclicAMP induces the expression of the inhibitory Fc receptor, FcgammaRIIb. Immunol Lett vol. 83, (3) 171-179.
10.1016/S0165-2478(02)00118-9
McDonald KJ, Cameron AJM, Allen JM, McLay JS, Jardine AG(2002). A pathophysiological role for tubular Fc receptors in glomerulonephritis?. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY vol. 13, 175A-175A.
Hillyard DZ, Cameron AJM, McIntyre AH, Hadden MH, Marshall HE, Johnston N, Jardine AG(2002). Inhibition of proliferation and signalling mechanisms in human lymphocytes by fluvastatin. Clin Exp Pharmacol Physiol vol. 29, (8) 673-678.
10.1046/j.1440-1681.2002.03711.x
McDonald KJ, Cameron AJM, Allen JM, Jardine AG(2002). Expression of Fc alpha/mu receptor by human mesangial cells: a candidate receptor for immune complex deposition in IgA nephropathy. Biochem Biophys Res Commun vol. 290, (1) 438-442.
10.1006/bbrc.2001.6218
Cameron AJ, Harnett MM, Allen JM(2001). Differential recruitment of accessory molecules by FcgammaRI during monocyte differentiation. Eur J Immunol vol. 31, (9) 2718-2725.
10.1002/1521-4141(200109)31:9<2718::AID-IMMU2718>3.0.CO;2-7
Cameron AJ, Allen JM(1999). The human high-affinity immunoglobulin G receptor activates SH2-containing inositol phosphatase (SHIP). Immunology vol. 97, (4) 641-647.
10.1046/j.1365-2567.1999.00813.x
Melendez A, Floto RA, Cameron AJ, Gillooly DJ, Harnett MM, Allen JM(1998). A molecular switch changes the signalling pathway used by the Fc gamma RI antibody receptor to mobilise calcium. Curr Biol vol. 8, (4) 210-221.
10.1016/S0960-9822(98)70085-5
Cameron AJ, Allen JM(1997). Differential expression of the human high affinity IgG receptor Fc gamma RI and associated signalling molecules in differentiated U937 monocyte cells. Biochem Soc Trans vol. 25, (3)
10.1042/bst025502s
Leng J, Cameron AJ, Buckel S, Kennelly PJ(1995). Isolation and cloning of a protein-serine/threonine phosphatase from an archaeon. J Bacteriol vol. 177, (22) 6510-6517.
10.1128/jb.177.22.6510-6517.1995
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