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Publications:  Dr Sarah McClelland

Tovini L, McClelland SE(2020). Towards restoring proper chromosome segregation and preventing ageing. EMBO Reports vol. 21, (5)
10.15252/embr.202050322
Dumont M, Gamba R, Gestraud P, Klaasen S, Worrall JT, De Vries SG, Boudreau V, Salinas-Luypaert C et al.(2020). Human chromosome-specific aneuploidy is influenced by DNA-dependent centromeric features. EMBO J vol. 39, (2)
10.15252/embj.2019102924
McClelland SE(2019). Single-cell approaches to understand genome organisation throughout the cell cycle. Essays in Biochemistry vol. 63, (2) 209-216.
10.1042/EBC20180043
Johnson SC, McClelland SE(2019). Watching cancer cells evolve through chromosomal instability. Nature vol. 570, (7760) 166-167.
10.1038/d41586-019-01709-2
Tijhuis AE, Johnson SC, McClelland SE(2019). The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity. Molecular Cytogenetics vol. 12, (1)
10.1186/s13039-019-0429-1
Tovini L, McClelland SE(2019). Impaired CENP-E function renders large chromosomes more vulnerable to congression failure. Biomolecules vol. 9, (2)
10.3390/biom9020044
Currie CE, Mora-Santos M, Smith CA, McClelland SE, McAinsh AD, Millar JB (2018). Elucidating the role of Bub1 in human checkpoint signalling. MOLECULAR BIOLOGY OF THE CELL. vol. 29,
Worrall JT, Tamura N, Mazzagatti A, Shaikh N, van Lingen T, Bakker B, Spierings DCJ, Vladimirou E et al.(2018). Non-random Mis-segregation of Human Chromosomes. Cell Reports vol. 23, (11) 3366-3380.
10.1016/j.celrep.2018.05.047
https://qmro.qmul.ac.uk/xmlui/handle/123456789/53803
McClelland SE(2017). Role of chromosomal instability in cancer progression. Endocr Relat Cancer vol. 24, (9) T23-T31.
10.1530/ERC-17-0187
Worrall JT, McClelland SE (2016). Determining the Missegregation Rates of Individual Human Chromosomes. CYTOGENETIC AND GENOME RESEARCH. vol. 148, 131-131.
Worrall JT, McClelland SE (2016). Determining the missegregation rates of individual human chromosomes. MOLECULAR BIOLOGY OF THE CELL. vol. 27,
Tamura N, Shaikh N, McGuinness JR, Bowtell D, Balkwill F, Petermann E, McClelland SE (2016). What drives chromosomal instability in high-grade serous ovarian cancer?. MOLECULAR BIOLOGY OF THE CELL. vol. 27,
Burrell RA, McClelland SE, Bartek J, Swanton C(2014). Response to Bakhoum et al. Curr Biol vol. 24, (4)
10.1016/j.cub.2014.01.021
Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller M-C, Shaikh N, Domingo E, Kanu N et al.(2013). Replication stress links structural and numerical cancer chromosomal instability. Nature vol. 494, (7438) 492-496.
10.1038/nature11935
Burrell RA, McClelland SE, Endesfelder D, Rowan A, Schenk A, Sheffer M, Shaikh N, Domingo E et al. (2012). Chromosome 18q encodes a chromosomal instability suppressor locus in colorectal cancer. CANCER RESEARCH. vol. 72,
10.1158/1538-7445.AM2012-3105
Burrell RA, McClelland SE, Juul N, Downward J, Szallasi Z, Swanton C (2009). Regulators of Mitotic Transition Determine Paclitaxel Resistance In Vitro and Predict Poor Prognosis in Breast Cancer In Vivo. CANCER RESEARCH. vol. 69, 641S-641S.
McClelland SE, Burrell RA, Swanton C(2009). Chromosomal instability: a composite phenotype that influences sensitivity to chemotherapy. Cell Cycle vol. 8, (20) 3262-3266.
10.4161/cc.8.20.9690
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