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Publications:  Dr Bela Wrench

WRENCH BR(2017). Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukemia. Nature Communications vol. 7, Article 13331,
10.1038/ncomms13331
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18925
WRENCH BR(2017). Pegylated-asparaginase during induction therapy for adult acute lymphoblastic leukaemia: toxicity data from the UKALL14 trial. leukaemia
10.1038/leu.2016.219
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18902
Dey A, Zhang Y, Castleton AZ, Bailey K, Beaton B, Patel B, Fielding AK(2016). The Role of Neutrophils in Measles Virus-mediated Oncolysis Differs Between B-cell Malignancies and Is Not Always Enhanced by GCSF. Mol Ther vol. 24, (1) 184-192.
10.1038/mt.2015.149
Roberts KG, Payne-Turner D, McCastlain K, Gu Z, Iacobucci I, Harvey RC, Chen I-M, Valentine M et al. (2015). High Frequency and Poor Outcome of Ph-like Acute Lymphoblastic Leukemia in Adults. BLOOD. vol. 126,
Patel B, Dey A, Castleton AZ, Schwab C, Samuel E, Sivakumaran J, Beaton B, Zareian N et al.(2014). Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology. Blood vol. 124, (1) 96-105.
10.1182/blood-2014-01-549352
Castleton A, Dey A, Beaton B, Patel B, Aucher A, Davis DM, Fielding AK(2014). Human mesenchymal stromal cells deliver systemic oncolytic measles virus to treat acute lymphoblastic leukemia in the presence of humoral immunity. Blood vol. 123, (9) 1327-1335.
10.1182/blood-2013-09-528851
Fielding AK, Rowe JM, Buck G, Foroni L, Gerrard G, Litzow MR, Lazarus H, Luger SM et al.(2014). UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia. Blood vol. 123, (6) 843-850.
10.1182/blood-2013-09-529008
Moorman AV, Schwab C, Ensor HM, Russell LJ, Morrison H, Jones L, Masic D, Patel B et al.(2012). IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia. J Clin Oncol vol. 30, (25) 3100-3108.
10.1200/JCO.2011.40.3907
Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK(2012). Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function. J Immunol vol. 188, (3) 1002-1010.
10.4049/jimmunol.1102262
Patel B, Dey A, Ghorani E, Kumar S, Malam Y, Rai L, Steele AJ, Thomson J et al.(2011). Differential cytopathology and kinetics of measles oncolysis in two primary B-cell malignancies provides mechanistic insights. Mol Ther vol. 19, (6) 1034-1040.
10.1038/mt.2011.44
Patel B, Rai L, Buck G, Richards SM, Mortuza Y, Mitchell W, Gerrard G, Moorman AV et al.(2010). Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993. Br J Haematol vol. 148, (1) 80-89.
10.1111/j.1365-2141.2009.07941.x
Patel B, Kirkland KE, Szydlo R, Pearce RM, Clark RE, Craddock C, Liakopoulou E, Fielding AK et al.(2009). Favorable outcomes with alemtuzumab-conditioned unrelated donor stem cell transplantation in adults with high-risk Philadelphia chromosome-negative acute lymphoblastic leukemia in first complete remission. Haematologica vol. 94, (10) 1399-1406.
10.3324/haematol.2009.008649
Mansour MR, Duke V, Foroni L, Patel B, Allen CG, Ancliff PJ, Gale RE, Linch DC(2007). Notch-1 mutations are secondary events in some patients with T-cell acute lymphoblastic leukemia. Clin Cancer Res vol. 13, (23) 6964-6969.
10.1158/1078-0432.CCR-07-1474
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