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Publications:  Dr James Garnett

Gu S, Vladimir VE, Shaw R et al. (2017) . The role of intrinsic disorder and dynamics in the assembly and function of the type II secretion system.BBA - Proteins and Proteomics
Lee W-C, Matthews S, Garnett JA (2016) . Crystal structure and analysis of HdaB: The enteroaggregative Escherichia coli AAF/IV pilus tip protein.Protein Science vol. 25, (10) 1898-1905.
Rasheed M, Garnett J, Pérez-Dorado I et al. (2016) . Crystal structure of the CupB6 adhesive tip from the chaperone-usher family of pili from Pseudomonas aeruginosa.Biochim Biophys Acta vol. 1864, (11) 1500-1505.
Taglialegna A, Navarro S, Ventura S et al. (2016) . Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals.PLoS Pathogens vol. 12, (6) e1005711-e1005711.
Wong CT, Xu Y, Gupta A et al. (2015) . Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family.Nat Commun vol. 6,
Pakharukova N, Garnett JA, Tuittila M et al. (2015) . Structural Insight into Archaic and Alternative Chaperone-Usher Pathways Reveals a Novel Mechanism of Pilus Biogenesis.PLoS Pathog vol. 11, (11)
Miliara X, Garnett JA, Tatsuta T et al. (2015) . Structural insight into the TRIAP1/PRELI‐like domain family of mitochondrial phospholipid transfer complexes.EMBO reports
Garnett JA, Diallo M, Matthews SJ (2015) . Purification, crystallization and preliminary X-ray diffraction analysis of the Escherichia coli common pilus chaperone EcpB.Acta Crystallographica Section F vol. 71, Article 6, 676-679.
Garnett JA, Muhl D, Douse CH et al. (2015) . Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation.Protein science : a publication of the Protein Society
Young JC, Clements A, Lang AE et al. (2014) . The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation.NATURE COMMUNICATIONS vol. 5, Article ARTN 5887,
Douse CH, Maas SJ, Thomas JC et al. (2014) . Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein–Helix Interaction.ACS Chemical Biology vol. 9, (10) 2204-2209.
Berry AA, Yang Y, Pakharukova N et al. (2014) . Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli.PLoS Pathogens vol. 10, (9)
Mousnier A, Schroeder GN, Stoneham CA et al. (2014) . A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases.mBio vol. 5, (4) Article e01148-14,
Lin J, Oh S-H, Jones R et al. (2014) . The peptide-binding cavity is essential for ALS3-mediated adhesion of Candida albicans to human cells.Journal of Biological Chemistry vol. 289, (26) 18401-18412.
Lambert SM, Langley DR, Garnett JA et al. (2014) . The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors.Protein Sci vol. 23, (6) 723-734.
Liu B, Garnett JA, Lee W et al. (2012) . Promoting Crystallization of the Salmonella enteritidis fimbriae 14 pilin SefD using Deuterium Oxide.Biochem Biophys Res Commun vol. 421, (2) 208-213.
Garnett JA, Martínez-Santos VI, Saldaña Z et al. (2012) . Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus.Proc Natl Acad Sci U S A vol. 109, (10) 3950-3955.
Garnett JA, Simpson PJ, Taylor J et al. (2012) . Structural insight into the role of Streptococcus parasanguinis Fap1 within oral biofilm formation.Biochem Biophys Res Commun vol. 417, (1) 421-426.
Garnett JA, Matthews S (2012) . Interactions in bacterial biofilm development: A structural perspective.Current Protein and Peptide Science vol. 13, (8) 739-755.
Lai L, Bumstead J, Liu Y et al. (2011) . The Role of Sialyl Glycan Recognition in Host Tissue Tropism of the Avian Parasite Eimeria tenella.PLoS Pathog vol. 7, (10)
Yang Y, Garnett JA, Matthews S (2011) . Crystallization and initial crystallographic analysis of AafA: the major adhesive subunit of the enteroaggregative Escherichia coli AAF/II pilus.Acta Crystallographica Section F vol. 67, Article 4, 454-456.
Garnett JA, Ramboarina S, Lee W-C et al. (2011) . Crystallization and initial crystallographic analysis of the Streptococcus parasanguinis FW213 Fap1-\-NR$\sb α$ adhesive domain at pH 5.0.Acta Crystallographica Section F vol. 67, Article 2, 274-276.
Yang Y, Berry A, Lee W et al. (2011) . Complete 1H, 13C and 15N NMR assignments for donor-strand complemented AafA, the major pilin of aggregative adherence fimbriae (AAF/II) from enteroaggregative E. coli.Biomolecular NMR Assignments vol. 5, (1) 1-5.
Bulgin R, Raymond B, Garnett JA et al. (2010) . Bacterial Guanine Nucleotide Exchange Factors SopE-Like and WxxxE Effectors.Infect Immun vol. 78, (4) 1417-1425.
Arbeloa A, Garnett J, Lillington J et al. (2010) . EspM2 is a RhoA guanine nucleotide exchange factor.Cellular Microbiology vol. 12, Article 5, 654-664.
Ramboarina S, Garnett JA, Zhou M et al. (2010) . Structural Insights into Serine-rich Fimbriae from Gram-positive Bacteria.Journal of Biological Chemistry vol. 285, Article 42, 32446-32457.
Garnett JA, Liu Y, Leon E et al. (2009) . Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.Protein Sci vol. 18, (9) 1935-1947.
Allman SA, Jensen HH, Vijayakrishnan B et al. (2009) . Potent Fluoro-oligosaccharide Probes of Adhesion in Toxoplasmosis.ChemBioChem vol. 10, Article 15, 2522-2529.
Dunsmore CJ, Miller K, Blake KL et al. (2008) . 2-Aminotetralones: Novel inhibitors of MurA and MurZ.Bioorganic & Medicinal Chemistry Letters vol. 18, Article 5, 1730-1734.
Garnett JA, Marincs F, Baumberg S et al. (2008) . Structure and Function of the Arginine Repressor-Operator Complex from Bacillus subtilis.Journal of Molecular Biology vol. 379, Article 2, 284-298.
Stead MA, Trinh CH, Garnett JA et al. (2007) . A Beta-Sheet Interaction Interface Directs the Tetramerisation of the Miz-1 POZ Domain.Journal of Molecular Biology vol. 373, (4) 820-826.
Garnett JA, Baumberg S, Stockley PG et al. (2007) . A high-resolution structure of the DNA-binding domain of AhrC, the arginine repressor/activator protein from Bacillus subtilis.Acta Crystallographica Section F vol. 63, Article 11, 914-917.
Garnett JA, Baumberg S, Stockley PG et al. (2007) . Structure of the C-terminal effector-binding domain of AhrC bound to its corepressor \sc l-arginine.Acta Crystallographica Section F vol. 63, Article 11, 918-921.
GARNETT JA, Gu, S, Shevchik VE et al.. The role of intrinsic disorder and dynamics in the assembly and function of the type II secretion system.BBA - Proteins and Proteomics
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