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Publications:  Dr James Garnett

White RC, Gunderson FF, Tyson JY et al.(2018). Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas. mBio vol. 9, (2) e00528-18-e00528-18.
10.1128/mBio.00528-18
http://qmro.qmul.ac.uk/xmlui/handle/123456789/36509
Gu S, Vladimir VE, Shaw R et al.(2017). The role of intrinsic disorder and dynamics in the assembly and function of the type II secretion system. BBA - Proteins and Proteomics
10.1016/j.bbapap.2017.07.006
http://qmro.qmul.ac.uk/xmlui/handle/123456789/25099
Lee W-C, Matthews S, Garnett JA(2016). Crystal structure and analysis of HdaB: The enteroaggregative Escherichia coli AAF/IV pilus tip protein. Protein Science vol. 25, (10) 1898-1905.
10.1002/pro.2982
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23176
Rasheed M, Garnett J, Pérez-Dorado I et al.(2016). Crystal structure of the CupB6 adhesive tip from the chaperone-usher family of pili from Pseudomonas aeruginosa. Biochim Biophys Acta vol. 1864, (11) 1500-1505.
10.1016/j.bbapap.2016.07.010
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23177
Taglialegna A, Navarro S, Ventura S et al.(2016). Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals. PLoS Pathogens vol. 12, (6) e1005711-e1005711.
10.1371/journal.ppat.1005711
http://qmro.qmul.ac.uk/xmlui/handle/123456789/23387
Wong CT, Xu Y, Gupta A et al.(2015). Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family. Nat Commun vol. 6,
10.1038/ncomms10172
Pakharukova N, Garnett JA, Tuittila M et al.(2015). Structural Insight into Archaic and Alternative Chaperone-Usher Pathways Reveals a Novel Mechanism of Pilus Biogenesis. PLoS Pathog vol. 11, (11)
10.1371/journal.ppat.1005269
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13457
Miliara X, Garnett JA, Tatsuta T et al.(2015). Structural insight into the TRIAP1/PRELI‐like domain family of mitochondrial phospholipid transfer complexes. EMBO reports
10.15252/embr.201540229
Garnett JA, Diallo M, Matthews SJ(2015). Purification, crystallization and preliminary X-ray diffraction analysis of the Escherichia coli common pilus chaperone EcpB. Acta Crystallographica Section F vol. 71, Article 6, 676-679.
10.1107/S2053230X15006354
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13453
Garnett JA, Muhl D, Douse CH et al.(2015). Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation. Protein science : a publication of the Protein Society
10.1002/pro.2640
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13458
Young JC, Clements A, Lang AE et al.(2014). The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation. NATURE COMMUNICATIONS vol. 5, Article ARTN 5887,
10.1038/ncomms6887
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13455
Douse CH, Maas SJ, Thomas JC et al.(2014). Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein–Helix Interaction. ACS Chemical Biology vol. 9, (10) 2204-2209.
10.1021/cb500271c
Berry AA, Yang Y, Pakharukova N et al.(2014). Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli. PLoS Pathogens vol. 10, (9)
10.1371/journal.ppat.1004404
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13456
Mousnier A, Schroeder GN, Stoneham CA et al.(2014). A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases. mBio vol. 5, (4) Article e01148-14,
10.1128/mBio.01148-14
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13459
Lin J, Oh S-H, Jones R et al.(2014). The peptide-binding cavity is essential for ALS3-mediated adhesion of Candida albicans to human cells. Journal of Biological Chemistry vol. 289, (26) 18401-18412.
10.1074/jbc.M114.547877
Lambert SM, Langley DR, Garnett JA et al.(2014). The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors. Protein Sci vol. 23, (6) 723-734.
10.1002/pro.2456
Liu B, Garnett JA, Lee W et al.(2012). Promoting Crystallization of the Salmonella enteritidis fimbriae 14 pilin SefD using Deuterium Oxide. Biochem Biophys Res Commun vol. 421, (2) 208-213.
10.1016/j.bbrc.2012.03.136
Garnett JA, Martínez-Santos VI, Saldaña Z et al.(2012). Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus. Proc Natl Acad Sci U S A vol. 109, (10) 3950-3955.
10.1073/pnas.1106733109
Garnett JA, Simpson PJ, Taylor J et al.(2012). Structural insight into the role of Streptococcus parasanguinis Fap1 within oral biofilm formation. Biochem Biophys Res Commun vol. 417, (1) 421-426.
10.1016/j.bbrc.2011.11.131
Garnett JA, Matthews S(2012). Interactions in bacterial biofilm development: A structural perspective. Current Protein and Peptide Science vol. 13, (8) 739-755.
10.2174/138920312804871166
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13849
Lai L, Bumstead J, Liu Y et al.(2011). The Role of Sialyl Glycan Recognition in Host Tissue Tropism of the Avian Parasite Eimeria tenella. PLoS Pathog vol. 7, (10)
10.1371/journal.ppat.1002296
Yang Y, Garnett JA, Matthews S(2011). Crystallization and initial crystallographic analysis of AafA: the major adhesive subunit of the enteroaggregative Escherichia coli AAF/II pilus. Acta Crystallographica Section F vol. 67, Article 4, 454-456.
10.1107/S1744309111001412
Garnett JA, Ramboarina S, Lee W-C et al.(2011). Crystallization and initial crystallographic analysis of the Streptococcus parasanguinis FW213 Fap1-\-NR$\sb α$ adhesive domain at pH 5.0. Acta Crystallographica Section F vol. 67, Article 2, 274-276.
10.1107/S1744309110052772
Yang Y, Berry A, Lee W et al.(2011). Complete 1H, 13C and 15N NMR assignments for donor-strand complemented AafA, the major pilin of aggregative adherence fimbriae (AAF/II) from enteroaggregative E. coli. Biomolecular NMR Assignments vol. 5, (1) 1-5.
10.1007/s12104-010-9252-7
Bulgin R, Raymond B, Garnett JA et al.(2010). Bacterial Guanine Nucleotide Exchange Factors SopE-Like and WxxxE Effectors. Infect Immun vol. 78, (4) 1417-1425.
10.1128/IAI.01250-09
Arbeloa A, Garnett J, Lillington J et al.(2010). EspM2 is a RhoA guanine nucleotide exchange factor. Cellular Microbiology vol. 12, Article 5, 654-664.
10.1111/j.1462-5822.2009.01423.x
http://qmro.qmul.ac.uk/xmlui/handle/123456789/13847
Ramboarina S, Garnett JA, Zhou M et al.(2010). Structural Insights into Serine-rich Fimbriae from Gram-positive Bacteria. Journal of Biological Chemistry vol. 285, Article 42, 32446-32457.
10.1074/jbc.M110.128165
Garnett JA, Liu Y, Leon E et al.(2009). Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii. Protein Sci vol. 18, (9) 1935-1947.
10.1002/pro.204
Allman SA, Jensen HH, Vijayakrishnan B et al.(2009). Potent Fluoro-oligosaccharide Probes of Adhesion in Toxoplasmosis. ChemBioChem vol. 10, Article 15, 2522-2529.
10.1002/cbic.200900425
Dunsmore CJ, Miller K, Blake KL et al.(2008). 2-Aminotetralones: Novel inhibitors of MurA and MurZ. Bioorganic & Medicinal Chemistry Letters vol. 18, Article 5, 1730-1734.
10.1016/j.bmcl.2008.01.089
Garnett JA, Marincs F, Baumberg S et al.(2008). Structure and Function of the Arginine Repressor-Operator Complex from Bacillus subtilis. Journal of Molecular Biology vol. 379, Article 2, 284-298.
10.1016/j.jmb.2008.03.007
Stead MA, Trinh CH, Garnett JA et al.(2007). A Beta-Sheet Interaction Interface Directs the Tetramerisation of the Miz-1 POZ Domain. Journal of Molecular Biology vol. 373, (4) 820-826.
10.1016/j.jmb.2007.08.026
Garnett JA, Baumberg S, Stockley PG et al.(2007). A high-resolution structure of the DNA-binding domain of AhrC, the arginine repressor/activator protein from Bacillus subtilis. Acta Crystallographica Section F vol. 63, Article 11, 914-917.
10.1107/S1744309107048166
Garnett JA, Baumberg S, Stockley PG et al.(2007). Structure of the C-terminal effector-binding domain of AhrC bound to its corepressor \sc l-arginine. Acta Crystallographica Section F vol. 63, Article 11, 918-921.
10.1107/S1744309107049391
GARNETT JA, Gu, S, Shevchik VE et al.. The role of intrinsic disorder and dynamics in the assembly and function of the type II secretion system. BBA - Proteins and Proteomics
10.1016/j.bbapap.2017.07.006
http://qmro.qmul.ac.uk/xmlui/handle/123456789/25099
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