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Publications:  Dr Viji Draviam Sastry

Patel H, Stavrou I, Shrestha RL et al. (2016) . Kindlin1 regulates microtubule function to ensure normal mitosis.J Mol Cell Biol vol. 8, (4) 338-348.
10.1093/jmcb/mjw009
Hiroi N, Draviam VM, Funahashi A (2016) . Editorial: Quantitative Biology: Dynamics of Living Systems.Front Physiol vol. 7,
10.3389/fphys.2016.00196
Corrigan AM, Shrestha R, Draviam VM et al. (2015) . Modeling of Noisy Spindle Dynamics Reveals Separable Contributions to Achieving Correct Orientation.Biophys J vol. 109, (7) 1398-1409.
10.1016/j.bpj.2015.08.014
Tamura N, Simon JE, Nayak A et al. (2015) . A proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset.Biol Open vol. 4, (2) 155-169.
10.1242/bio.201410413
Ochi T, Blackford AN, Coates J et al. (2015) . DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.Science vol. 347, (6218) 185-188.
10.1126/science.1261971
Iorio F, Shrestha RL, Levin N et al. (2015) . A Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning Predictions.PLoS One vol. 10, (10)
10.1371/journal.pone.0139446
Nakai Y, Ozeki M, Hiraiwa T et al. (2015) . High-speed microscopy with an electrically tunable lens to image the dynamics of in vivo molecular complexes.Rev Sci Instrum vol. 86, (1)
10.1063/1.4905330
Shrestha RL, Draviam VM (2014) . Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK. MOLECULAR BIOLOGY OF THE CELL. vol. 25,
Conti D, Draviam VM (2014) . Role of phosphatases in chromosome segregation. MOLECULAR BIOLOGY OF THE CELL. vol. 25,
Shrestha RL, Tamura N, Fries A et al. (2014) . TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes.Open Biol vol. 4, (6)
10.1098/rsob.130108
Chin HMS, Nandra K, Clark J et al. (2014) . Need for multi-scale systems to identify spindle orientation regulators relevant to tissue disorganization in solid cancers.Front Physiol vol. 5,
10.3389/fphys.2014.00278
Shrestha RL, Draviam VM (2013) . Erratum: Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK (Current Biology (2013) 23 (1514-1526)).Current Biology vol. 23, (23) 2440-2441.
10.1016/j.cub.2013.11.015
Shrestha RL, Draviam VM (2013) . Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK.Curr Biol vol. 23, (16) 1514-1526.
10.1016/j.cub.2013.06.040
Corrigan AM, Shrestha RL, Zulkipli I et al. (2013) . Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance.Cell Cycle vol. 12, (16) 2643-2655.
10.4161/cc.25671
Tamura N, Draviam VM (2012) . Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.Open Biol vol. 2, (11)
10.1098/rsob.120132
Draviam VM, Funahashi A, Hiroi N et al. (2012) . Meeting report of the International Workshop on Quantitative Biology 2012: mesoscopic and microscopic worlds meet.Front Physiol vol. 3,
10.3389/fphys.2012.00479
Tamura N, Shrestha RL, Draviam VM (2012) . Microtubule-end bound complexes power chromosome movement during chromosome segregation. MOLECULAR BIOLOGY OF THE CELL. vol. 23,
Shrestha RL, Draviam VM (2012) . TAO1 maintains genome integrity by mediating the timely maturation of chromosome attachments made to lateral walls of microtubules. MOLECULAR BIOLOGY OF THE CELL. vol. 23,
Shrestha RL, Tamura N, Zulkipli I et al. (2011) . A mechanism linking microtubule destabilisation to maturation of chromosome-microtubule attachments. MOLECULAR BIOLOGY OF THE CELL. vol. 22,
Pagliuca C, Draviam VM, Marco E et al. (2009) . Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.PLoS One vol. 4, (10)
10.1371/journal.pone.0007640
McAinsh AD, Meraldi P, Draviam VM et al. (2009) . The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation (The EMBO Journal (2006) 25 (4033-4049) DOI:10.1038/sj.emboj.7601293).EMBO Journal vol. 28, (9)
10.1038/emboj.2009.94
Foijer F, Draviam VM, Sorger PK (2008) . Studying chromosome instability in the mouse.Biochim Biophys Acta vol. 1786, (1) 73-82.
10.1016/j.bbcan.2008.07.004
Stegmeier F, Rape M, Draviam VM et al. (2007) . Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.Nature vol. 447, (7141) 876-881.
Draviam VM, Stegmeier F, Nalepa G et al. (2007) . A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.Nat Cell Biol vol. 9, (5) 556-564.
10.1038/ncb1569
Stegmeier F, Rape M, Draviam VM et al. (2007) . Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.Nature vol. 446, (7138) 876-881.
10.1038/nature05694
Basto R, Gergely F, Draviam VM et al. (2007) . Hsp90 is required to localise cyclin B and Msps/ch-TOG to the mitotic spindle in Drosophila and humans.J Cell Sci vol. 120, (Pt 7) 1278-1287.
10.1242/jcs.000604
McAinsh AD, Meraldi P, Draviam VM et al. (2006) . The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation.EMBO J vol. 25, (17) 4033-4049.
10.1038/sj.emboj.7601293
Draviam VM, Shapiro I, Aldridge B et al. (2006) . Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells.EMBO J vol. 25, (12) 2814-2827.
10.1038/sj.emboj.7601168
Draviam VM, Stegmeier F, Nalepa G et al. (2006) . Functional Genomic Screen Reveals the Role of a Novel Checkpoint Kinase, TAO1 in Mitosis and Cell Cycle Progression. MOLECULAR BIOLOGY OF THE CELL. vol. 17,
Meraldi P, Draviam VM, Sorger PK (2004) . Timing and checkpoints in the regulation of mitotic progression.Dev Cell vol. 7, (1) 45-60.
10.1016/j.devcel.2004.06.006
Draviam VM, Xie S, Sorger PK (2004) . Chromosome segregation and genomic stability.Curr Opin Genet Dev vol. 14, (2) 120-125.
10.1016/j.gde.2004.02.007
Gergely F, Draviam VM, Raff JW (2003) . The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells.Genes Dev vol. 17, (3) 336-341.
10.1101/gad.245603
Draviam VM, Orrechia S, Lowe M et al. (2001) . The localization of human cyclins B1 and B2 determines CDK1 substrate specificity and neither enzyme requires MEK to disassemble the Golgi apparatus.J Cell Biol vol. 152, (5) 945-958.
10.1083/jcb.152.5.945
Shrestha RL, Conti D, Tamura N et al.. Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells.Nat Commun vol. 8, (1)
10.1038/s41467-017-00209-z
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