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Publications:  Dr Viji Draviam Sastry

Zulkipli I, Clark J, HART M et al.(2018). Spindle rotation in human cells is reliant on a MARK2-mediated equatorial spindle centering mechanism. Journal of Cell Biology
10.1083/jcb.201804166
http://qmro.qmul.ac.uk/xmlui/handle/123456789/41928
Zulkipli I, Shrestha RL, Clark J et al. (2017). Proper rotation of the mitotic spindle requires an equatorial spindle centering mechanism in human cells. MOLECULAR BIOLOGY OF THE CELL. Conference: ASCB vol. 28,
Shrestha RL, Conti D, Tamura N et al.(2017). Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells. Nat Commun vol. 8, (1) 150-150.
10.1038/s41467-017-00209-z
http://qmro.qmul.ac.uk/xmlui/handle/123456789/34884
Conti D, Cieslinski KA, Ries J et al. (2017). Outer kinetochore phosphatases-PP2A-B56 and PP1-differently contribute to the establishment of chromosome-microtubule attachments. MOLECULAR BIOLOGY OF THE CELL. vol. 28,
Patel H, Stavrou I, Shrestha RL et al.(2016). Kindlin1 regulates microtubule function to ensure normal mitosis. J Mol Cell Biol vol. 8, (4) 338-348.
10.1093/jmcb/mjw009
Hiroi N, Draviam VM, Funahashi A(2016). Editorial: Quantitative Biology: Dynamics of Living Systems. Front Physiol vol. 7, Article 196,
10.3389/fphys.2016.00196
Corrigan AM, Shrestha R, Draviam VM et al.(2015). Modeling of Noisy Spindle Dynamics Reveals Separable Contributions to Achieving Correct Orientation. Biophys J vol. 109, (7) 1398-1409.
10.1016/j.bpj.2015.08.014
Tamura N, Simon JE, Nayak A et al.(2015). A proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset. Biol Open vol. 4, (2) 155-169.
10.1242/bio.201410413
Ochi T, Blackford AN, Coates J et al.(2015). DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science vol. 347, (6218) 185-188.
10.1126/science.1261971
Iorio F, Shrestha RL, Levin N et al.(2015). A Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning Predictions. PLoS One vol. 10, (10)
10.1371/journal.pone.0139446
Nakai Y, Ozeki M, Hiraiwa T et al.(2015). High-speed microscopy with an electrically tunable lens to image the dynamics of in vivo molecular complexes. Rev Sci Instrum vol. 86, (1)
10.1063/1.4905330
Shrestha RL, Draviam VM (2014). Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK. MOLECULAR BIOLOGY OF THE CELL. vol. 25,
Conti D, Draviam VM (2014). Role of phosphatases in chromosome segregation. MOLECULAR BIOLOGY OF THE CELL. vol. 25,
Shrestha RL, Tamura N, Fries A et al.(2014). TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes. Open Biol vol. 4, (6)
10.1098/rsob.130108
Chin HMS, Nandra K, Clark J et al.(2014). Need for multi-scale systems to identify spindle orientation regulators relevant to tissue disorganization in solid cancers. Front Physiol vol. 5,
10.3389/fphys.2014.00278
Shrestha RL, Draviam VM(2013). Erratum: Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK (Current Biology (2013) 23 (1514-1526)). Current Biology vol. 23, (23) 2440-2441.
10.1016/j.cub.2013.11.015
Shrestha RL, Draviam VM(2013). Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK. Curr Biol vol. 23, (16) 1514-1526.
10.1016/j.cub.2013.06.040
Corrigan AM, Shrestha RL, Zulkipli I et al.(2013). Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance. Cell Cycle vol. 12, (16) 2643-2655.
10.4161/cc.25671
Tamura N, Draviam VM(2012). Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles. Open Biol vol. 2, (11)
10.1098/rsob.120132
Draviam VM, Funahashi A, Hiroi N et al.(2012). Meeting report of the International Workshop on Quantitative Biology 2012: mesoscopic and microscopic worlds meet. Front Physiol vol. 3,
10.3389/fphys.2012.00479
Tamura N, Shrestha RL, Draviam VM (2012). Microtubule-end bound complexes power chromosome movement during chromosome segregation. MOLECULAR BIOLOGY OF THE CELL. vol. 23,
Shrestha RL, Draviam VM (2012). TAO1 maintains genome integrity by mediating the timely maturation of chromosome attachments made to lateral walls of microtubules. MOLECULAR BIOLOGY OF THE CELL. vol. 23,
Shrestha RL, Tamura N, Zulkipli I et al. (2011). A mechanism linking microtubule destabilisation to maturation of chromosome-microtubule attachments. MOLECULAR BIOLOGY OF THE CELL. vol. 22,
Pagliuca C, Draviam VM, Marco E et al.(2009). Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint. PLoS One vol. 4, (10)
10.1371/journal.pone.0007640
McAinsh AD, Meraldi P, Draviam VM et al.(2009). The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation (The EMBO Journal (2006) 25 (4033-4049) DOI:10.1038/sj.emboj.7601293). EMBO Journal vol. 28, (9)
10.1038/emboj.2009.94
Foijer F, Draviam VM, Sorger PK(2008). Studying chromosome instability in the mouse. Biochim Biophys Acta vol. 1786, (1) 73-82.
10.1016/j.bbcan.2008.07.004
Stegmeier F, Rape M, Draviam VM et al.(2007). Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities. Nature vol. 447, (7141) 876-881.
Draviam VM, Stegmeier F, Nalepa G et al.(2007). A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling. Nat Cell Biol vol. 9, (5) 556-564.
10.1038/ncb1569
Stegmeier F, Rape M, Draviam VM et al.(2007). Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities. Nature vol. 446, (7138) 876-881.
10.1038/nature05694
Basto R, Gergely F, Draviam VM et al.(2007). Hsp90 is required to localise cyclin B and Msps/ch-TOG to the mitotic spindle in Drosophila and humans. J Cell Sci vol. 120, (Pt 7) 1278-1287.
10.1242/jcs.000604
McAinsh AD, Meraldi P, Draviam VM et al.(2006). The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation. EMBO J vol. 25, (17) 4033-4049.
10.1038/sj.emboj.7601293
Draviam VM, Shapiro I, Aldridge B et al.(2006). Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells. EMBO J vol. 25, (12) 2814-2827.
10.1038/sj.emboj.7601168
Draviam VM, Stegmeier F, Nalepa G et al. (2006). Functional Genomic Screen Reveals the Role of a Novel Checkpoint Kinase, TAO1 in Mitosis and Cell Cycle Progression. MOLECULAR BIOLOGY OF THE CELL. vol. 17,
Meraldi P, Draviam VM, Sorger PK(2004). Timing and checkpoints in the regulation of mitotic progression. Dev Cell vol. 7, (1) 45-60.
10.1016/j.devcel.2004.06.006
Draviam VM, Xie S, Sorger PK(2004). Chromosome segregation and genomic stability. Curr Opin Genet Dev vol. 14, (2) 120-125.
10.1016/j.gde.2004.02.007
Gergely F, Draviam VM, Raff JW(2003). The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells. Genes Dev vol. 17, (3) 336-341.
10.1101/gad.245603
Draviam VM, Orrechia S, Lowe M et al.(2001). The localization of human cyclins B1 and B2 determines CDK1 substrate specificity and neither enzyme requires MEK to disassemble the Golgi apparatus. J Cell Biol vol. 152, (5) 945-958.
10.1083/jcb.152.5.945
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