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Publications:  Dr Gareth Ackland

Walker SLM, Muthoo C, Sanchez J, Del Arroyo AG, Ackland GL (2020). Sex influences cardiac dysfunction in early polymicrobial sepsis, independent of leucocyte-derived tumour necrosis factor-alpha. BRITISH JOURNAL OF ANAESTHESIA. vol. 124, E204-E205.
Ackland GL, ABBOTT T, Jones TF, Leuwer M, Pearse R, Niebrzegowska E, Wragg A, Archbold A et al.(2020). Early elevation in plasma high-sensitivity troponin T and morbidity after elective noncardiac surgery: prospective multicentre observational cohort study. British Journal of Anaesthesia
10.1016/j.bja.2020.02.003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63282
Wijeysundera D, Beattie WS, Hillis G, ABBOTT T, Shulman M, Ackland G, Mazer D, Myles P et al.(2019). Integration of the Duke Activity Status Index into Preoperative Risk Evaluation: A Multicentre Prospective Cohort Study. British Journal of Anaesthesia
10.1016/j.bja.2019.11.025
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62126
Manou-Stathopoulou V, Korbonits M, Ackland GL(2019). Redefining the perioperative stress response: a narrative review. British Journal of Anaesthesia vol. 123, (5) 570-583.
10.1016/j.bja.2019.08.011
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62840
Zarbock A, Kellum JA, Gourine AV, Ackland GL(2019). Salvaging remote ischaemic preconditioning as a therapy for perioperative acute kidney injury. British Journal of Anaesthesia vol. 124, (1) 8-12.
10.1016/j.bja.2019.09.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62205
May SM, Reyes A, Martir G, Reynolds J, Paredes LG, Karmali S, Stephens RCM, Brealey D et al.(2019). Acquired loss of cardiac vagal activity is associated with myocardial injury in patients undergoing noncardiac surgery: prospective observational mechanistic cohort study. British Journal of Anaesthesia vol. 123, (6) 758-767.
10.1016/j.bja.2019.08.003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61920
del Arroyo AG, Hadjihambi A, Sanchez J, Turovsky E, Kasymov V, Cain D, Nightingale TD, Lambden S et al.(2019). NMDA receptor modulation of glutamate release in activated neutrophils. EBioMedicine
10.1016/j.ebiom.2019.08.004
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60722
Ackland GL, Pryor KO(2019). Electroencephalography-guided anaesthetic administration does not impact postoperative delirium among older adults undergoing major surgery: an independent discussion of the ENGAGES trial. British Journal of Anaesthesia vol. 123, (2) 112-117.
10.1016/j.bja.2019.03.016
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59190
The Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators(2019). Association between complications and death within 30 days after noncardiac surgery. Canadian Medical Association Journal vol. 191, (30) E830-E837.
10.1503/cmaj.190221
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60052
Lau EYM, Carroll EC, Callender LA, Hood GA, Berryman V, Pattrick M, Finer S, Hitman GA et al.(2019). Type 2 diabetes is associated with the accumulation of senescent T cells. Clinical & Experimental Immunology
10.1111/cei.13344
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58984
Bartoszko J, Thorpe KE, Laupacis A, Wijeysundera DN, Myles PS, Shulman MA, Wallace S, Farrington C et al.(2019). Association of preoperative anaemia with cardiopulmonary exercise capacity and postoperative outcomes in noncardiac surgery: a substudy of the Measurement of Exercise Tolerance before Surgery (METS) Study. British Journal of Anaesthesia
10.1016/j.bja.2019.04.058
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58398
Peden CJ, Stephens T, Martin G, Kahan BC, Thomson A, Rivett K, Wells D, Richardson G et al.(2019). Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial. The Lancet vol. 393, (10187) 2213-2221.
10.1016/S0140-6736(18)32521-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54603
ABBOTT TEF, PEARSE RM, beattie S, Phull M, Beilstein C, Raj A, Grocott M, Cuthbertson B et al.(2019). Chronotropic incompetence and myocardial injury after non-cardiac surgery: planned secondary analysis of a prospective observational international cohort study. BJA: British Journal of Anaesthesia vol. 123, (1) 17-26.
10.1016/j.bja.2019.03.022
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56417
Sessler DI, Bloomstone JA, Aronson S, Berry C, Gan TJ, Kellum JA, Plumb J, Mythen MG et al.(2019). Perioperative Quality Initiative consensus statement on intraoperative blood pressure, risk and outcomes for elective surgery. British Journal of Anaesthesia vol. 122, (5) 563-574.
10.1016/j.bja.2019.01.013
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58425
Ackland GL, Brudney CS, Cecconi M, Ince C, Irwin MG, Lacey J, Pinsky MR, Grocott MP et al.(2019). Perioperative Quality Initiative consensus statement on the physiology of arterial blood pressure control in perioperative medicine. British Journal of Anaesthesia vol. 122, (5) 542-551.
10.1016/j.bja.2019.01.011
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58876
McEvoy MD, Gupta R, Koepke EJ, Feldheiser A, Michard F, Levett D, Thacker JKM, Hamilton M et al.(2019). Perioperative Quality Initiative consensus statement on postoperative blood pressure, risk and outcomes for elective surgery. British Journal of Anaesthesia
10.1016/j.bja.2019.01.019
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58819
Gourine AV, Ackland GL(2019). Cardiac Vagus and Exercise. Physiology (Bethesda) vol. 34, (1) 71-80.
10.1152/physiol.00041.2018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55136
Abbott TEF, Pearse RM, Cuthbertson BH, Wijeysundera DN, Ackland GL(2019). Cardiac vagal dysfunction and myocardial injury after non-cardiac surgery: a planned secondary analysis of the measurement of Exercise Tolerance before surgery study. British Journal of Anaesthesia
10.1016/j.bja.2018.10.060
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57537
Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA et al.(2019). Correction: Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies (PLoS ONE (2019) 14:8 (e0221277) DOI: 10.1371/journal.pone.0221277). PLoS ONE vol. 14, (12)
10.1371/journal.pone.0226379
Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA et al.(2019). Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies. PLoS ONE vol. 14, (8)
10.1371/journal.pone.0221277
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61876
ACKLAND GL(2019). Perioperative Quality Initiative consensus statement on preoperative blood pressure, risk and outcomes for elective surgery. British Journal of Anaesthesia
10.1016/j.bja.2019.01.018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59001
del Arroyo AG, Sanchez J, Patel S, Phillips S, Reyes A, Cubillos C, Fernando R, David AL et al.(2018). Role of leucocyte caspase-1 activity in epidural-related maternal fever: a single-centre, observational, mechanistic cohort study. British Journal of Anaesthesia
10.1016/j.bja.2018.09.024
https://qmro.qmul.ac.uk/xmlui/handle/123456789/51743
Ackland GL, Galley HF, Shelley B, Lambert DG(2018). Perioperative medicine and UK plc. British Journal of Anaesthesia
10.1016/j.bja.2018.09.023
https://qmro.qmul.ac.uk/xmlui/handle/123456789/51863
Ackland GL, Abbott TEF, Cain D, Edwards MR, Sultan P, Karmali SN, Fowler AJ, Whittle JR et al.(2018). Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery. British Journal of Anaesthesia
10.1016/j.bja.2018.09.002
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49203
TORRANCE H, LONGBOTTOM R, VIVIAN M, Lalabekyan B, ABBOTT TEF, ACKLAND GL, HINDS CJ, PEARSE RM et al.(2018). Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery. PLoS ONE vol. 13, (9)
10.1371/journal.pone.0203795
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45023
Wijeysundera D, PEARSE R, shulman M, ABBOTT TEF, Torres E, Ambosta A, Bernard C, Granton J et al.(2018). Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study. Lancet vol. 391, (10140) 2631-2640.
10.1016/S0140-6736(18)31131-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42364
WALKER S, ABBOTT TEF, Brown K, PEARSE R, ACKLAND G(2018). Perioperative management of angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers: a survey of perioperative medicine practitioners. PeerJ
10.7717/peerj.5061
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42127
Lurati Buse G, Manns B, Lamy A, Guyatt G, Polanczyk CA, Chan MTV, Wang CY, Villar JC et al.(2018). Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost–consequence analysis. Canadian Journal of Surgery vol. 61, (3) 185-194.
10.1503/cjs.010217
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39863
ackland GL, ABBOTT T, Pearse RM, Karmali S, Whittle J, Minto G(2018). Arterial pulse pressure and postoperative morbidity in high-risk surgical patients. British Journal of Anaesthesia vol. 120, (1) 94-100.
10.1016/j.bja.2017.11.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24953
Karmali SN, Sciusco A, May SM, Ackland GL(2017). Heart rate variability in critical care medicine: a systematic review. Intensive Care Med Exp vol. 5, (1)
10.1186/s40635-017-0146-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25320
ABBOTT T, pearse RM, Archbold RA, Ahmad T, Niebrzegowska E, Wragg A, Rodseth R, Devereaux PJ et al.(2017). A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study. Anesthesia and Analgesia vol. 126, (6) 1936-1945.
10.1213/ANE.0000000000002560
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36643
ACKLAND GL, Minto G, Clark M, Whittle J, Stephens RCM, Owen T, Prabhu P, del Arroyo AG(2017). Autonomic regulation of systemic inflammation in humans: a multi-center, blinded observational cohort study. Brain, Behavior, and Immunity
10.1016/j.bbi.2017.08.010
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25329
ABBOTT T, pearse R, ahmad T, ackland G(2017). Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery. British Journal Of Anaesthesia vol. 119, (1) 78-86.
10.1093/bja/aex165
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25477
ABBOTT T, Lee A, Pearse R, Ackland G, Minto G(2017). Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients. British Journal Of Anaesthesia vol. 119, (1) 87-94.
10.1093/bja/aex164
https://qmro.qmul.ac.uk/xmlui/handle/123456789/25476
Patel A, Prowle JR, Ackland GL, POM-O Study Investigators(2017). Postoperative goal-directed therapy and development of acute kidney injury following major elective noncardiac surgery: post-hoc analysis of POM-O randomized controlled trial. Clin Kidney J vol. 10, (3) 348-356.
10.1093/ckj/sfw118
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24486
Machhada A, Trapp S, Marina N, Stephens RCM, Whittle J, Lythgoe MF, Kasparov S, Ackland GL et al.(2017). Vagal determinants of exercise capacity. Nature Communications vol. 8,
10.1038/ncomms15097
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24525
Biccard BM, Scott DJA, Chan MTV, Archbold A, Wang C-Y, Sigamani A, Urrútia G, Cruz P et al.(2017). Myocardial Injury After Noncardiac Surgery (MINS) in Vascular Surgical Patients: A Prospective Observational Cohort Study. Ann Surg
10.1097/SLA.0000000000002290
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23524
Writing Committee for the VISION Study Investigators, Devereaux PJ, Biccard BM, Sigamani A, Xavier D, Chan MTV, Srinathan SK, Walsh M et al.(2017). Association of Postoperative High-Sensitivity Troponin Levels With Myocardial Injury and 30-Day Mortality Among Patients Undergoing Noncardiac Surgery. JAMA vol. 317, (16) 1642-1651.
10.1001/jama.2017.4360
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58626
O'Connor ME, Hewson RW, Kirwan CJ, Ackland GL, Pearse RM, Prowle JR(2017). Acute kidney injury and mortality 1 year after major non-cardiac surgery. British Journal of Surgery
10.1002/bjs.10498
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19798
Basalay M, Mastitskaya S, Mrochek A, Ackland GL, Arroyo AGD, Sanchez J, Sjoquist P-O, Pernow J et al.(2017). Reply: Glucagon-like peptide-1 mediates cardioprotection by remote ischaemic conditioning. Cardiovasc Res vol. 113, (1) 13-14.
10.1093/cvr/cvw238
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61678
Basalay MV, Mastitskaya S, Mrochek A, Ackland GL, Del Arroyo AG, Sanchez J, Sjoquist PO, Pernow J et al.(2016). Glucagon-like peptide-1 (GLP-1) mediates cardioprotection by remote ischaemic conditioning. Cardiovascular research vol. 112, (3) 669-676.
10.1093/cvr/cvw216
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16286
Turovsky E, Theparambil SM, Kasymov V, Deitmer JW, Del Arroyo AG, Ackland GL, Corneveaux JJ, Allen AN et al.(2016). Mechanisms of CO<inf>2</inf>/H<sup>+</sup> sensitivity of astrocytes. Journal of Neuroscience vol. 36, (42) 10750-10758.
10.1523/JNEUROSCI.1281-16.2016
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23060
Toner A, Jenkins N, Ackland GL(2016). Baroreflex impairment and morbidity after major surgery. British Journal of Anaesthesia vol. 117, (3) 324-331.
10.1093/bja/aew257
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15182
Ackland GL, Whittle J, Toner A, Machhada A, Del Arroyo AG, Sciuso A, Jenkins N, Dyson A et al.(2016). Molecular Mechanisms Linking Autonomic Dysfunction and Impaired Cardiac Contractility in Critical Illness. Crit Care Med vol. 44, (8) e614-e624.
10.1097/CCM.0000000000001606
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12159
Abbott TEF, Ackland GL, Archbold RA, Wragg A, Kam E, Ahmad T, Khan AW, Niebrzegowska E et al.(2016). Preoperative heart rate and myocardial injury after non-cardiac surgery: results of a predefined secondary analysis of the VISION study. British Journal of Anaesthesia vol. 117, (2) 172-181.
10.1093/bja/aew182
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13922
Ackland GL, Stephens RCM(2016). Big Data: A Cheerleader for Translational Perioperative Medicine. Anesth Analg vol. 122, (6) 1744-1747.
10.1213/ANE.0000000000001286
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16007
Sultan P, David AL, Fernando R, Ackland GL(2016). Inflammation and Epidural-Related Maternal Fever. Anesthesia & Analgesia vol. 122, (5) 1546-1553.
10.1213/ANE.0000000000001195
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12269
Ackland GL, Mythen MG(2016). Physiology of the gastrointestinal tract including splanchnic blood flow and tonometry. Gastrointestinal and Colorectal Anesthesia,
Wijeysundera DN, Pearse RM, Shulman MA, Abbott TEF, Torres E, Croal BL, Granton JT, Thorpe KE et al.(2016). Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery. BMJ Open vol. 6, (3) e010359-e010359.
10.1136/bmjopen-2015-010359
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12155
Marina N, Kasymov V, Ackland GL, Kasparov S, Gourine AV(2016). Astrocytes and brain hypoxia. vol. 903, 201-207.
10.1007/978-1-4899-7678-9_14
Nelson A, Otto J, Whittle J, Stephens RCM, Martin DS, Prowle JR, Ackland GL(2016). Subclinical cardiopulmonary dysfunction in stage 3 chronic kidney disease. Open Heart vol. 3, (1)
10.1136/openhrt-2015-000370
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12835
Abbott T, Ackland GL, Wragg A, Rodseth R, Archbold A, Pearse RM(2015). Association between intraoperative heart rate and postoperative myocardial injury in patients following non-cardiac surgery. Intensive Care Med Exp vol. 3, (Suppl 1) A751-A751.
10.1186/2197-425X-3-S1-A751
Abbott T, Ackland G, Wragg A, Archbold A, Devereaux P, Pearse R (2015). Association of preoperative heart rate with postoperative myocardial injury. BRITISH JOURNAL OF ANAESTHESIA. vol. 115, E958-E959.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15463
Karmali S, Jenkins N, Sciusco A, John J, Haddad F, Ackland GL(2015). Randomized controlled trial of vagal modulation by sham feeding in elective non-gastrointestinal (orthopaedic) surgery. British Journal of Anaesthesia vol. 115, (5) 727-735.
10.1093/bja/aev283
Abbott T, Rodseth R, Le Manach Y, Ackland G, Archbold A, Wragg A, Devereaux P, Pearse R (2015). Association between preoperative resting heart rate and postoperative myocardial injury in patients undergoing non-cardiac surgery. ANAESTHESIA. vol. 70, 28-28.
10.1186/2197-425x-3-s1-a751
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14811
Milne A, Mon WYU, Down J, Obichere A, Ackland GL(2015). Contemporary perioperative management of adult familial dysautonomia (Riley-Day syndrome). A &amp; A case reports vol. 4, (9) 111-113.
10.1213/XAA.0000000000000141
Cain DJ, Del Arroyo AG, Ackland GL(2015). Man is the new mouse: Elective surgery as a key translational model for multi-organ dysfunction and sepsis. Journal of the Intensive Care Society vol. 16, (2) 154-163.
10.1177/1751143714564826
Ackland GL, Cecconi M, Pearse RM(2015). Individualised targeted haemodynamic therapy in high-risk surgical patients - authors' reply. The Lancet. Respiratory medicine vol. 3, (4) e14-e15.
10.1016/s2213-2600(15)00100-9
Machhada A, Ang R, Ackland GL, Ninkina N, Buchman VL, Lythgoe MF, Trapp S, Tinker A et al.(2015). Control of ventricular excitability by neurons of the dorsal motor nucleus of the vagus nerve. Heart Rhythm vol. 12, (11) 2285-2293.
10.1016/j.hrthm.2015.06.005
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13063
Barsukevich V, Basalay M, Sanchez J, Mrochek A, Whittle J, Ackland GL, Gourine AV, Gourine A(2015). Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning. Basic Research in Cardiology vol. 110, (1)
10.1007/s00395-014-0452-7
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12974
Angelova PR, Kasymov V, Christie I, Sheikhbahaei S, Turovsky E, Marina N, Korsak A, Zwicker J et al.(2015). Functional oxygen sensitivity of astrocytes. Journal of Neuroscience vol. 35, (29) 10460-10473.
10.1523/JNEUROSCI.0045-15.2015
Ackland GL, Iqbal S, Paredes LG, Toner A, Lyness C, Jenkins N, Bodger P, Karmali S et al.(2015). Individualised oxygen delivery targeted haemodynamic therapy in high-risk surgical patients: A multicentre, randomised, double-blind, controlled, mechanistic trial. The Lancet Respiratory Medicine vol. 3, (1) 33-41.
10.1016/S2213-2600(14)70205-X
Ackland GL, Igbal S, Paredes LG, Toner A, Lyness C, Jenkins N, Bodger P, Karmali S et al.(2015). Individualised oxygen delivery targeted haemodynamic therapy in high-risk surgical patients: a multicentre, randomised, double-blind, controlled, mechanistic trial. LANCET RESPIRATORY MEDICINE vol. 3, (1) 33-41.
10.1016/s2213-2600(14)70205-X
Edwards MR, Sultan P, del Arroyo AG, Whittle J, Karmali SN, Ramani Moonesinghe S, Haddad FS, Mythen MG et al.(2015). Metabolic dysfunction in lymphocytes promotes postoperative morbidity. Clinical Science vol. 129, (5) 423-437.
10.1042/CS20150024
Patel ABU, Reyes A, Ackland GL(2015). Non-inferiority of retrospective data collection for assessing perioperative morbidity. PeerJ vol. 2015, (12)
10.7717/peerj.1466
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13270
Ackland GL, Prowle JR(2015). Presepsin: solving a soluble (CD14) problem in sepsis?. Intensive Care Medicine vol. 41, (2) 351-353.
10.1007/s00134-014-3642-8
Whittle J, Nelson A, Otto JM, Stephens RCM, Martin DS, Sneyd JR, Struthers R, Minto G et al.(2015). Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis. Open Heart vol. 2, (1)
10.1136/openhrt-2015-000268
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12977
Machhada A, Gourine AV, Ackland GL(2015). Vagal Modulation of Atrial Fibrillation. Journal of the American College of Cardiology vol. 66, (8) 977-978.
10.1016/j.jacc.2015.04.083
Henderson WR, Barnbrook J, Dominelli PB, Griesdale DE, Arndt T, Molgat-Seon Y, Foster G, Ackland GL et al.(2014). Administration of intrapulmonary sodium polyacrylate to induce lung injury for the development of a porcine model of early acute respiratory distress syndrome. Intensive Care Med Exp vol. 2, (1)
10.1186/2197-425X-2-5
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12975
Ackland GL, Laing CM(2014). Chronic kidney disease: a gateway for perioperative medicine. British journal of anaesthesia vol. 113, (6) 902-905.
10.1093/bja/aeu222
Cain DJ, Del Arroyo AG, Ackland GL(2014). Uncontrolled sepsis: a systematic review of translational immunology studies in intensive care medicine. Intensive Care Med Exp vol. 2, (1)
10.1186/2197-425X-2-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13410
Machhada A, Ang R, Ninkina N, Buchman VL, Ackland GL, Lythgoe MF, Marina N, Gourine AV (2014). A CNS cell group that controls electrical stability of the heart. EUROPEAN HEART JOURNAL. vol. 35, 435-435.
Machhada A, Gourine AV, Lythgoe MF, Ackland GL (2014). Vagal mechanisms controlling exercise capacity. EUROPEAN HEART JOURNAL. vol. 35, 953-953.
Sultan P, Edwards MR, Gutierrez Del Arroyo A, Cain D, Sneyd JR, Struthers R, Minto G, Ackland GL(2014). Cardiopulmonary exercise capacity and preoperative markers of inflammation. Mediators of Inflammation vol. 2014,
10.1155/2014/727451
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12973
Pearse RM, Harrison DA, MacDonald N, Gillies MA, Blunt M, Ackland G, Grocott MPW, Ahern A et al.(2014). Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery a randomized clinical trial and systematic review. JAMA - Journal of the American Medical Association vol. 311, (21) 2181-2190.
10.1001/jama.2014.5305
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11483
Botto F, Alonso-Coello P, Chan MTV, Villar JC, Xavier D, Srinathan S, Guyatt G, Cruz P et al.(2014). Myocardial Injury after Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes. Anesthesiology vol. 120, (3) 564-578.
10.1097/ALN.0000000000000113
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9817
Fragkou PC, Torrance HD, Pearse RM, Ackland GL, Prowle JR, Owen HC, Hinds CJ, O'Dwyer MJ(2014). Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study. Crit Care vol. 18, (5) 014-0541.
10.1186/s13054-014-0541-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12111
Ackland GL, Kazymov V, Marina N, Singer M, Gourine AV(2013). Peripheral neural detection of danger-associated and pathogen-associated molecular patterns. Critical Care Medicine vol. 41, (6)
10.1097/CCM.0b013e31827c0b05
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12972
Mastitskaya S, Marina N, Gourine A, Gilbey MP, Spyer KM, Teschemacher AG, Kasparov S, Trapp S et al.(2012). Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones. Cardiovascular Research vol. 95, (4) 487-494.
10.1093/cvr/cvs212
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12971
Pearse RM, Ackland GL(2012). Perioperative fluid therapy. Praxis vol. 101, (17) 1113-1118.
10.1024/1661-8157/a001028
Pearse RM, Ackland GL(2012). Perioperative fluid therapy. BMJ (Online) vol. 344, (7855)
10.1136/bmj.e2865
Ackland GL(2012). In response. Anesthesia and Analgesia vol. 114, (3)
10.1213/ANE.0b013e318245dd26
Holm L, Ackland GL, Edwards MR, Breckenridge RA, Sim RB, Offer J(2012). Chemical labelling of active serum thioester proteins for quantification. Immunobiology vol. 217, (2) 256-264.
10.1016/j.imbio.2011.07.021
Sultan P, Hamilton MA, Ackland GL(2012). Preoperative muscle weakness as defined by handgrip strength and postoperative outcomes: A systematic review. BMC Anesthesiology vol. 12,
10.1186/1471-2253-12-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12993
Dyson A, Cone S, Singer M, Ackland GL(2012). Microvascular and macrovascular flow are uncoupled in early polymicrobial sepsis. British Journal of Anaesthesia vol. 108, (6) 973-978.
10.1093/bja/aes093
Basalay M, Barsukevich V, Mastitskaya S, Mrochek A, Pernow J, Sjöquist PO, Ackland GL, Gourine AV et al.(2012). Remote ischaemic pre- and delayed postconditioning - similar degree of cardioprotection but distinct mechanisms. Experimental Physiology vol. 97, (8) 908-917.
10.1113/expphysiol.2012.064923
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15422
Edwards M, Whittle J, Ackland GL(2011). Biomarkers to guide perioperative management. Postgraduate Medical Journal vol. 87, (1030) 542-549.
10.1136/pgmj.2010.107177
Ackland GL, Moran N, Cone S, Grocott MPW, Mythen MG(2011). Chronic kidney disease and postoperative morbidity after elective orthopedic surgery. Anesthesia and Analgesia vol. 112, (6) 1375-1381.
10.1213/ANE.0b013e3181ee8456
Ackland GL(2011). Reply from the authors. British Journal of Anaesthesia vol. 106, (5)
10.1093/bja/aer070
Ackland GL, Dyson A, Singer M(2010). Arterial hyperoxia and in-hospital mortality after resuscitation from cardiac arrest [1]. JAMA - Journal of the American Medical Association vol. 304, (13)
10.1001/jama.2010.1396
Barnes SJ, Singer M, Ackland GL (2010). DOBUTAMINE STRESS ECHOCARDIOGRAPHY UNMASKS MYOCARDIAL DYSFUNCTION IN EARLY RODENT POLYMICROBIAL SEPSIS. INTENSIVE CARE MEDICINE. vol. 36, S334-S334.
del Arroyo AG, Singer M, Ackland GL (2010). NEURO-IMMUNOMODULATION OF HUMAN CD14+CD16+NEUTROPHILS IN SEPSIS. INTENSIVE CARE MEDICINE. vol. 36, S409-S409.
Ackland GL, Edwards M(2010). Defining higher-risk surgery. Current Opinion in Critical Care vol. 16, (4) 339-346.
10.1097/MCC.0b013e328339fad5
Barnes SJ, Ackland GL(2010). Beta-adrenoreceptor modulation of metabolic, endocrine and immunologic function during critical illness. Endocrine, Metabolic and Immune Disorders - Drug Targets vol. 10, (3) 292-300.
10.2174/187153010791936883
Ackland GL, Yao ST, Rudiger A, Dyson A, Stidwill R, Poputnikov D, Singer M, Gourine AV(2010). Cardioprotection, attenuated systemic inflammation, and survival benefit of β1-adrenoceptor blockade in severe sepsis in rats. Critical Care Medicine vol. 38, (2) 388-394.
10.1097/CCM.0b013e3181c03dfa
Ackland GL, Gutierrez Del Arroyo A, Yao ST, Stephens RC, Dyson A, Klein NJ, Singer M, Gourine AV(2010). Low-molecular-weight polyethylene glycol improves survival in experimental sepsis. Critical Care Medicine vol. 38, (2) 629-636.
10.1097/CCM.0b013e3181c8fcd0
Ackland GL, Harris S, Ziabari Y, Grocott M, Mythen M(2010). Revised cardiac risk index and postoperative morbidity after elective orthopaedic surgery: A prospective cohort study. British Journal of Anaesthesia vol. 105, (6) 744-752.
10.1093/bja/aeq245
Ackland GL, O'Beirne J, Platts AR, Ward SC(2008). False-positive presentation of Battle's sign during hepatic encephalopathy. Neurocritical Care vol. 9, (2) 253-255.
10.1007/s12028-008-9116-5
Ackland GL, Harrington J, Downie P, Holding JW, Singh-Ranger D, Griva K, Mythen MG, Newman SP(2008). Dehydration induced by bowel preparation in older adults does not result in cognitive dysfunction. Anesthesia and Analgesia vol. 106, (3) 924-929.
10.1213/ane.0b013e3181615247
Ackland GL, Patterson AJ(2007). The pivotal role of beta-adrenoreceptors in critical illness pathophysiology. Yearbook of Intensive Care and Emergency Medicine 2009,
Ackland GL, Mythen MG(2007). Novel biomarkers in critical care: Utility or futility?. Critical Care vol. 11, (6)
10.1186/cc6127
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14988
Ackland GL, Kasymov V, Gourine AV(2007). Physiological and pathophysiological roles of extracellular ATP in chemosensory control of breathing. Biochemical Society Transactions vol. 35, (5) 1264-1268.
10.1042/BST0351264
Ackland GL, Scollay JM, Parks RW, De Beaux I, Mythen MG(2007). Pre-operative high sensitivity C-reactive protein and postoperative outcome in patients undergoing elective orthopaedic surgery. Anaesthesia vol. 62, (9) 888-894.
10.1111/j.1365-2044.2007.05176.x
Ackland GL, Smith M, McGlennan AP(2007). Acute, severe hypoglycemia occurring during general anesthesia in a nondiabetic adult [35]. Anesthesia and Analgesia vol. 105, (2) 553-554.
10.1213/01.ane.0000268143.05226.a0
Hamilton MA, Mythen MG, Ackland GL(2006). Less is not more: A lack of evidence for intraoperative fluid restriction improving outcome after major elective gastrointestinal surgery [15]. Anesthesia and Analgesia vol. 102, (3) 970-971.
10.1213/01.ANE.0000190877.56380.FE
Spyer KM, Ackland GL, Gourine AV(2006). Neurophysiology: Overview. Encyclopedia of Respiratory Medicine, Four-Volume Set,
Ackland GL, Fox R(2005). Low-dose propofol infusion for controlling acute hyperspasticity after withdrawal of intrathecal baclofen therapy. Anesthesiology vol. 103, (3) 663-665.
10.1097/00000542-200509000-00033
Ackland GL, Mythen MG(2005). Negative pressure pulmonary edema as an unsuspected imitator of acute lung injury/ARDS [10]. Chest vol. 127, (5) 1867-1868.
10.1378/chest.127.5.1867-a
Ackland GL, Singh-Ranger D, Fox S, McClaskey B, Down JF, Farrar D, Sivaloganathan M, Mythen MG(2004). Assessment of preoperative fluid depletion using bioimpedence analysis. British Journal of Anaesthesia vol. 92, (1) 134-136.
10.1093/bja/aeh015
Ackland GL, Gourine AV, Spyer KM (2003). Endotoxin impairs the hypoxic ventilatory response in anaesthetized adult rats. INTENSIVE CARE MEDICINE. vol. 29, S86-S86.
Ackland GL, Noble R, Hanson MA(1997). Red nucleus inhibits breathing during hypoxia in neonates. Respiration Physiology vol. 110, (2-3) 251-260.
10.1016/S0034-5687(97)00090-X
Waites BA, Ackland GL, Noble R, Hanson MA(1996). Red nucleus lesions abolish the biphasic respiratory response to isocapnic hypoxia in decerebrate young rabbits. Journal of Physiology vol. 495, (1) 217-225.
10.1113/jphysiol.1996.sp021586
Moore PJ, Ackland GL, Hanson MA(1996). Unilateral cooling in the region of locus coeruleus blocks the fall in respiratory output during hypoxia in anaesthetized neonatal sheep. Experimental Physiology vol. 81, (6) 983-994.
10.1113/expphysiol.1996.sp003998
WAITES BA, ACKLAND GL, NOBLE R, HANSON MA (1995). MICROINJECTION OF L-GLUTAMATE IN THE RED NUCLEUS PRODUCES INHIBITION OF RESPIRATORY OUTPUT IN DECEREBRATE NEONATAL RABBITS. JOURNAL OF PHYSIOLOGY-LONDON. vol. 489P, P156-P156.
ACKLAND GL, WAITES BA, NOBLE R, HANSON MA (1995). BILATERAL LESIONS IN THE RED NUCLEUS ABOLISH THE BIPHASIC RESPIRATORY RESPONSE TO HYPOXIA IN DECEREBRATE NEWBORN RABBITS. JOURNAL OF PHYSIOLOGY-LONDON. vol. 483P, P89-P89.
Ackland GL, Moore PJ, Hanson MA(1994). Is the ventilatory decline seen in newborns during hypoxaemia centrally mediated?. Advances in Experimental Medicine and Biology vol. 360, 345-348.
10.1007/978-1-4615-2572-1_63
Ackland GL, Moore PJ, Hanson MA (1993). Hypoxia inhibits the effect on breathing of transient chemoreceptor stimulation in anaesthetized newborn rabbits. Journal of Physiology. vol. 467,
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