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Publications:  Dr Robert Keers

Rayner C, Coleman JRI, Purves KL, Hodsoll J, Goldsmith K, Alpers GW, Andersson E, Arolt V et al.(2019). A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Translational Psychiatry vol. 9, (1)
10.1038/s41398-019-0481-y
Reardon T, Creswell C, Lester KJ, Arendt K, Blatter-Meunier J, Bögels SM, Coleman JRI, Cooper PJ et al.(2019). The utility of the SCAS-C/P to detect specific anxiety disorders among clinically anxious children. Psychological Assessment vol. 31, (8) 1006-1018.
10.1037/pas0000700
Roberts S, Keers R, Breen G, Coleman JRI, Jöhren P, Kepa A, Lester KJ, Margraf J et al.(2019). DNA methylation of FKBP5 and response to exposure-based psychological therapy. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 180, (2) 150-158.
10.1002/ajmg.b.32650
Fox E, Keers R(2019). Bringing together cognitive and genetic approaches to the understanding of stress vulnerability and psychological well-being. Nebraska Symposium on Motivation, vol. 66,
Vincent J, Booth C, Songco A, Parson S, Kruijt A-W, Grol M, Spronk D, Keers R et al. (2019). THE GENETICS OF COGNITIVE BIASES IN THE DEVELOPMENT OF PSYCHIATRIC DISORDERS. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 29, 1294-1294.
10.1016/j.euroneuro.2018.08.414
Ullrich S, Keers R, Shaw J, Doyle M, Coid JW(2018). Acting on delusions: the role of negative affect in the pathway towards serious violence. Journal of Forensic Psychiatry and Psychology vol. 29, (5) 691-704.
10.1080/14789949.2018.1434227
KEERS R(2018). The Impact of Treatment Delivery Format on Response to Cognitive Behaviour Therapy for Pre-Adolescent Children with Anxiety Disorders. Journal of Child Psychology and Psychiatry
10.1111/jcpp.12872
https://qmro.qmul.ac.uk/xmlui/handle/123456789/36334
Booth C, Songco A, Parsons S, Heathcote L, Vincent J, Keers R, Fox E(2017). The CogBIAS longitudinal study protocol: cognitive and genetic factors influencing psychological functioning in adolescence. BMC Psychol vol. 5, (1) 41-41.
10.1186/s40359-017-0210-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32743
PLUESS M, Keers R(2017). Childhood Quality Influences Genetic Sensitivity to Environmental Influences across Adulthood: A Life-Course Gene-Environment Interaction Study. Development and Psychopathology
10.1017/S0954579417001493
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23260
Denis D, Eley TC, Rijsdijk F, Zavos HMS, Keers R, Espie CA, Luik AI, Badini I et al.(2017). Sleep Treatment Outcome Predictors (STOP) Pilot Study: a protocol for a randomised controlled trial examining predictors of change of insomnia symptoms and associated traits following cognitive-behavioural therapy for insomnia in an unselected sample. BMJ Open vol. 7, (11) e017177-e017177.
10.1136/bmjopen-2017-017177
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32763
Assary E, Vincent J, Keers R, PLUESS M(2017). Gene-Environment Interaction and Psychiatric Disorders: Review and Future Directions. Seminars in Cell and Developmental Biology
10.1016/j.semcdb.2017.10.016
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28312
Coleman J, Lester K, Keers R, Roberts S, Lee SH, de Jong S, Teismann T, Wannemueller A et al. (2017). COMBINING GENETIC AND GENE EXPRESSION METHODS TO IDENTIFY BIOLOGICAL PREDICTORS OF RESPONSE TO COGNITIVE BEHAVIOURAL THERAPY FOR ANXIETY DISORDERS. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 27, S159-S159.
Eley T, Keers R, Coleman J, Lester K, Thastum M, Schneider S, Heiervang E, Meiser-Stedman R et al. (2017). POLYGENIC SCORES FOR DIFFERENTIAL SUSCEPTIBILITY TO EMOTIONAL SYMPTOMS PREDICT RESPONSE TO CBT IN CHILD ANXIETY. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 27, S502-S503.
10.1016/j.euroneuro.2016.09.606
Roberts S, Wong CCY, Breen G, Coleman JRI, De Jong S, Jöhren P, Keers R, Curtis C et al.(2017). Genome-wide expression and response to exposure-based psychological therapy for anxiety disorders. Transl Psychiatry vol. 7, (8) e1219-e1219.
10.1038/tp.2017.177
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32664
Coleman JRI, Lester KJ, Keers R, Munafò MR, Breen G, Eley TC(2017). Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders. Am J Med Genet B Neuropsychiatr Genet vol. 174, (7) 701-711.
10.1002/ajmg.b.32558
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32723
Eley T, Keers R, Coleman J, Lester K, Roberts S, Breen G, Thastum M, Bogels S et al. (2016). Therapygenetics: using polygenic risk scores for differential susceptibility to predict response to psychological therapy in child anxiety disorders. BEHAVIOR GENETICS. vol. 46, 780-781.
Coleman JRI, Lester KJ, Keers R, Roberts S, Curtis C, Arendt K, Bögels S, Cooper P et al.(2016). Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders. British Journal of Psychiatry vol. 209, (3) 236-243.
10.1192/bjp.bp.115.168229
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32683
Coleman JRI, Lester KJ, Roberts S, Keers R, Lee SH, De Jong S, Gaspar H, Teismann T et al.(2016). Separate and combined effects of genetic variants and pre-treatment whole blood gene expression on response to exposure-based cognitive behavioural therapy for anxiety disorders. World Journal of Biological Psychiatry1-34.
10.1080/15622975.2016.1208841
Lester KJ, Coleman JRI, Roberts S, Keers R, Breen G, Bögels S, Creswell C, Hudson JL et al.(2016). Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
10.1002/ajmg.b.32467
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23204
González RA, Kallis C, Ullrich S, Barnicot K, Keers R, Coid JW(2016). Childhood maltreatment and violence: Mediation through psychiatric morbidity. Child Abuse and Neglect vol. 52, 70-84.
10.1016/j.chiabu.2016.01.002
Lester KJ, Roberts S, Keers R, Coleman JRI, Breen G, Wong CCY, Xu X, Arendt K et al.(2016). Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders. British Journal of Psychiatry vol. 208, (2) 182-188.
10.1192/bjp.bp.114.154997
Keers R, Coleman JRI, Lester KJ, Roberts S, Breen G, Thastum M, Bögels S, Schneider S et al.(2016). A Genome-Wide Test of the Differential Susceptibility Hypothesis Reveals a Genetic Predictor of Differential Response to Psychological Treatments for Child Anxiety Disorders. Psychotherapy and psychosomatics vol. 85, (3) 146-158.
10.1159/000444023
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32684
Coid JW, Ullrich S, Bebbington P, Fazel S, Keers R(2016). Paranoid ideation and violence: Meta-analysis of individual subject data of 7 population surveys. Schizophrenia Bulletin vol. 42, (4) 907-915.
10.1093/schbul/sbw006
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15968
Roberts S, Keers R, Lester KJ, Coleman JRI, Breen G, Arendt K, Blatter-Meunier J, Cooper P et al.(2015). HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS. Depress Anxiety vol. 32, (12) 861-870.
10.1002/da.22430
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32783
Hudson JL, Keers R, Roberts S, Coleman JRI, Breen G, Arendt K, Bögels S, Cooper P et al.(2015). Clinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study. Journal of the American Academy of Child and Adolescent Psychiatry vol. 54, (6) 454-463.
10.1016/j.jaac.2015.03.018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/32703
Eley TC, Lester KJ, Roberts S, Coleman RI, Keers R, Breen G, Wong CY, Hudson JL (2014). Genetic predictors of psychotherapy for mood and anxiety disorders. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 24, S141-S142.
10.1016/S0924-977X(14)70204-4
Keers R(2014). Response to Pinta. American Journal of Psychiatry vol. 171, (7)
10.1176/appi.ajp.2014.14030296r
Malki K, Keers R, Tosto MG, Lourdusamy A, Carboni L, Domenici E, Uher R, McGuffin P et al.(2014). The endogenous and reactive depression subtypes revisited: Integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder. BMC Medicine vol. 12, (1)
10.1186/1741-7015-12-73
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11230
Keers R, Ullrich S, DeStavola BL, Coid JW(2014). Association of violence with emergence of persecutory delusions in untreated schizophrenia. American Journal of Psychiatry vol. 171, (3) 332-339.
10.1176/appi.ajp.2013.13010134
Hodgson K, Uher R, Crawford AA, Lewis G, O'Donovan MC, Keers R, Dernovšek MZ, Mors O et al.(2014). Genetic predictors of antidepressant side effects: A grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study. Journal of Psychopharmacology vol. 28, (2) 142-150.
10.1177/0269881113517957
Ullrich S, Keers R, Coid JW(2013). Delusions, Anger, and Serious Violence: New Findings From the MacArthur Violence Risk Assessment Study. Schizophr Bull vol. n/a, Article n/a,
10.1093/schbul/sbt126
Power RA, Wingenbach T, Cohen-Woods S, Uher R, Ng MY, Butler AW, Ising M, Craddock N et al.(2013). Estimating the heritability of reporting stressful life events captured by common genetic variants. Psychological Medicine vol. 43, (9) 1965-1971.
10.1017/S0033291712002589
Coid JW, Ullrich S, Keers R, Bebbington P, Destavola BL, Kallis C, Yang M, Reiss D et al.(2013). Gang membership, violence, and psychiatric morbidity. Am J Psychiatry vol. 170, (9) 985-993.
10.1176/appi.ajp.2013.12091188
Power RA, Lecky-Thompson L, Fisher HL, Cohen-Woods S, Hosang GM, Uher R, Powell-Smith G, Keers R et al.(2013). The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression. Journal of Psychiatric Research vol. 47, (8) 1032-1035.
10.1016/j.jpsychires.2013.03.017
Coid JW, Ullrich S, Kallis C, Keers R, Barker D, Cowden F, Stamps R(2013). The relationship between delusions and violence: Findings from the East London first episode psychosis study. JAMA Psychiatry vol. 70, (5) 465-471.
10.1001/jamapsychiatry.2013.12
Malki K, Lourdusamy A, Binder E, Payá-Cano J, Sluyter F, Craig I, Keers R, McGuffin P et al.(2012). Antidepressant-dependent mRNA changes in mouse associated with hippocampal neurogenesis in a mouse model of depression. Pharmacogenetics and Genomics vol. 22, (11) 765-776.
10.1097/FPC.0b013e328356fa90
Power RA, Keers R, Ng MY, Butler AW, Uher R, Cohen-Woods S, Ising M, Craddock N et al.(2012). Dissecting the Genetic Heterogeneity of Depression Through Age at Onset. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics vol. 159 B, (7) 859-868.
10.1002/ajmg.b.32093
Malki K, Campbell J, Davies M, Keers R, Uher R, Ward M, Paya-Cano J, Aitchinson KJ et al.(2012). Pharmacoproteomic investigation into antidepressant response in two mouse inbred strains. Proteomics vol. 12, (14) 2355-2365.
10.1002/pmic.201100306
Keers R, Pedroso I, Breen G, Aitchison KJ, Nolan PM, Cichon S, Nöthen MM, Rietschel M et al.(2012). Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours. PLoS ONE vol. 7, (6)
10.1371/journal.pone.0038263
https://qmro.qmul.ac.uk/xmlui/handle/123456789/11231
Zavos HMS, Wong CCY, Barclay NL, Keers R, Mill J, Rijsdijk FV, Gregory AM, Eley TC(2012). Anxiety sensitivity in adolescence and young adulthood: The role of stressful life events, 5HTTLPR and their interaction. Depression and Anxiety vol. 29, (5) 400-408.
10.1002/da.21921
Keers R(2012). Will gene-environment interactions explain differential antidepressant response?. Personalized Medicine vol. 9, (3) 319-322.
10.2217/pme.12.28
Keers R, Uher R(2012). Gene-environment interaction in major depression and antidepressant treatment response. Current Psychiatry Reports vol. 14, (2) 129-137.
10.1007/s11920-011-0251-x
Fisher HL, Cohen-Woods S, Hosang GM, Uher R, Powell-Smith G, Keers R, Tropeano M, Korszun A et al.(2012). Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression. Journal of Affective Disorders vol. 136, (1-2) 189-193.
10.1016/j.jad.2011.09.016
Keers R, Bonvicini C, Scassellati C, Uher R, Placentino A, Giovannini C, Rietschel M, Henigsberg N et al.(2011). Variation in GNB3 predicts response and adverse reactions to antidepressants. Journal of Psychopharmacology vol. 25, (7) 867-874.
10.1177/0269881110376683
Uher R, Mors O, Hauser J, Rietschel M, Maier W, Kozel D, Henigsberg N, Souery D et al.(2011). Changes in body weight during pharmacological treatment of depression. International Journal of Neuropsychopharmacology vol. 14, (3) 367-375.
10.1017/S1461145710000933
Keers R, Uher R, Huezo-Diaz P, Smith R, Jaffee S, Rietschel M, Henigsberg N, Kozel D et al.(2011). Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project. Pharmacogenomics Journal vol. 11, (2) 138-145.
10.1038/tpj.2010.14
Amstadter AB, Balachandar V, Bergenb SE, Ceulemans S, Christensen JH, Cole J, Dagdan E, De Luca V et al.(2011). Erratum: Selected summaries from the XVII World Congress of Psychiatric Genetics, San Diego, California, USA, 4-8 November 2009 (Psychiatric Genetics (2010) 20:5 (229)). Psychiatric Genetics vol. 21, (1)
10.1097/YPG.0b013e328343171a
Keers R, Aitchison KJ(2011). Pharmacogenetics of antidepressant response. Expert Review of Neurotherapeutics vol. 11, (1) 101-125.
10.1586/ern.10.186
Keers R, Uher R, Gupta B, Rietschel M, Schulze TG, Hauser J, Skibinska M, Henigsberg N et al.(2010). Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEP. Journal of Affective Disorders vol. 127, (1-3) 337-342.
10.1016/j.jad.2010.06.011
Keers R, Aitchison KJ(2010). Gender differences in antidepressant drug response. International Review of Psychiatry vol. 22, (5) 485-500.
10.3109/09540261.2010.496448
Hosang GM, Uher R, Keers R, Cohen-Woods S, Craig I, Korszun A, Perry J, Tozzi F et al.(2010). Stressful life events and the brain-derived neurotrophic factor gene in bipolar disorder. Journal of Affective Disorders vol. 125, (1-3) 345-349.
10.1016/j.jad.2010.01.071
Amstadter AB, Balachandar V, Bergen SE, Ceulemans S, Christensen JH, Cole J, de Luca V, Ducci F et al.(2010). Selected summaries from the XVII world congress of psychiatric genetics, San Diego, California, USA, 4-8 November 2009. Psychiatric Genetics
10.1097/YPG.0b013e32833d17c3
Keers R, Ingelman-Sundberg M, Hauser J, Maier W, Rietschel M, Mors O, McGuffin P, Farmer AE et al. (2010). CYP2D6 genotype predicts antidepressant dose in the GENDEP project. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 20, S172-S173.
10.1016/S0924-977X(10)70148-6
Keers R, Farmer AE, Aitchison KJ(2010). Further evidence is required to confirm association between CACNA1C gene variants and bipolar affective disorder Reply. PSYCHOLOGICAL MEDICINE vol. 40, (4) 702-704.
Keers R, Farmer AE, Aitchison KJ(2010). The authors reply. Psychological Medicine vol. 40, (4) 702-704.
10.1017/S0033291710000012
Keers R, Ingelman-Sundberg M, Hauser J, Maier W, Rietschel M, Mors O, McGuffin P, Farmer AE et al. (2010). CYP2D6 and CYP2C19 genotypes predict antidepressant dose in the GENDEP project. EUROPEAN NEUROPSYCHOPHARMACOLOGY. vol. 20, S70-S71.
10.1016/S0924-977X(10)70082-1
Amstadter AB, Balachandar V, Bergen SE, Ceulemans S, Christensen JH, Cole J, De Luca V, Ducci F et al.(2010). Selected summaries from the XVII World Congress of Psychiatric Genetics, San Diego, California, USA, 4-8 November 2009. Psychiatric Genetics vol. 20, (5) 229-268.
10.1097/YPG.0b013e32833d17c3
Keers R, Farmer AE, Aitchison KJ(2009). Extracting a needle from a haystack: Reanalysis of whole genome data reveals a readily translatable finding. Psychological Medicine vol. 39, (8) 1231-1235.
10.1017/S0033291708005084
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