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Publications:  Prof Kamil Kranc

Luis TC, Lawson H, Kranc KR(2020). Divide and Rule: Mitochondrial Fission Regulates Quiescence in Hematopoietic Stem Cells. Cell Stem Cell vol. 26, (3) 299-301.
10.1016/j.stem.2020.02.009
Menendez-Gonzalez JB, Vukovic M, Abdelfattah A, Saleh L, Almotiri A, Thomas LA, Agirre-Lizaso A, Azevedo A et al.(2019). Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia. Stem Cell Reports vol. 13, (2) 291-306.
10.1016/j.stemcr.2019.07.005
Paris J, Morgan M, Campos J, Spencer GJ, Shmakova A, Ivanova I, Mapperley C, Lawson H et al.(2019). Targeting the RNA m<sup>6</sup>A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia. Cell Stem Cell vol. 25, (1) 137-148.e6.
10.1016/j.stem.2019.03.021
Van De Lagemaat LN, Flenley M, Lynch MD, Garrick D, Tomlinson SR, Kranc KR, Vernimmen D(2018). CpG binding protein (CFP1) occupies open chromatin regions of active genes, including enhancers and non-CpG islands 06 Biological Sciences 0601 Biochemistry and Cell Biology 06 Biological Sciences 0604 Genetics. Epigenetics and Chromatin vol. 11, (1)
10.1186/s13072-018-0230-0
Guitart AV, Finch AJ, Kranc KR(2018). Ca<sup>2+</sup>tapulting HSCs into action. Journal of Experimental Medicine vol. 215, (8) 1971-1973.
10.1084/jem.20181097
Pellicano F, Park L, Hopcroft LEM, Shah MM, Jackson L, Scott MT, Clarke CJ, Sinclair A et al.(2018). hsa-mir183/EGR1–mediated regulation of E2F1 is required for CML stem/progenitor cell survival. Blood vol. 131, (14) 1532-1544.
10.1182/blood-2017-05-783845
Guitart AV, Panagopoulou TI, Villacreces A, Vukovic M, Sepulveda C, Allen L, Carter RN, van de Lagemaat LN et al.(2017). Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions. The Journal of experimental medicine vol. 214, (3) 719-735.
10.1084/jem.20161087
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59365
Vukovic M, Sepulveda C, Subramani C, Guitart AV, Mohr J, Allen L, Panagopoulou TI, Paris J et al.(2016). Adult hematopoietic stem cells lacking Hif-1α self-renew normally. Blood vol. 127, (23) 2841-2846.
10.1182/blood-2015-10-677138
Guitart AV, Vukovic M, Sepulveda C, Panagopoulou T, Allen L, Pollard P, Morton N, Finch A et al. (2015). DUAL FUNCTION OF FUMARATE HYDRATASE IN HAEMATOPOIETIC STEM CELL FATES. EXPERIMENTAL HEMATOLOGY. vol. 43, S49-S49.
10.1016/j.exphem.2015.06.067
Guitart AV, Vukovic M, Sas Z, Vila M, Sepulveda C, Panagopoulou T, Allen L, Pollard P et al. (2015). FUMARATE HYDRATASE IS AN ESSENTIAL REGULATOR OF EMBRYONIC AND ADULT HAEMATOPOIETIC STEM CELL. HAEMATOLOGICA. vol. 100, 123-123.
Vukovic M, Guitart AV, Kranc K (2015). HIF-2A IS A TUMOUR SUPPRESSOR IN AML. HAEMATOLOGICA. vol. 100, 10-10.
Sepulveda C, Guitart A, Vukovic M, Panagopoulou TI, Allen L, Lengelling A, Ratcliffe PJ, Kranc KR (2015). THE ROLE OF 2-OXOGLUTARATE DEPENDENT DIOXYGENASES IN NORMAL HAEMATOPOIESIS AND ACUTE MYELOID LEUKEMIA. HAEMATOLOGICA. vol. 100, 9-9.
Vukovic M, Guitart AV, Sepulveda C, Villacreces A, O'Duibhir E, Panagopoulou TI, Ivens A, Menendez-Gonzalez J et al.(2015). Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance. Journal of Experimental Medicine vol. 212, (13) 2223-2234.
10.1084/jem.20150452
Sinclair A, Calaminus S, Pellicano F, Guitart A, Graham S, Poncz M, Graham G, Sansom O et al. (2013). CHEMOKINE SIGNALLING REGULATES HAEMOPOIETIC STEM CELL SURVIVAL. HAEMATOLOGICA. vol. 98, 391-392.
Guitart A, Pollard P, Holyoake T, Enver T, Ratcliffe P, Kranc K (2013). HIF-1ALPHA AND HIF-2APLPHA ARE NOT ESSENTIAL FOR STEADY-STATE HEMATOPOIETIC STEM CELL MAINTENANCE. HAEMATOLOGICA. vol. 98, 493-493.
Sinclair A, Pellicano P, Graham SM, Kinstrie R, Kranc K, Graham G, Holyoake TL (2012). An investigation of the role of CXCL1-CXCR2 signalling in haemopoietic stem cell quiescence. BRITISH JOURNAL OF HAEMATOLOGY. vol. 157, 26-27.
Clark JF, Pyne GJ, Tao LM, Claridge T, Harris D, Kranc K, Cadoux-Hudson T, Turnbull J et al. (2001). Oxidative degradation of bilirubin produces vasoactive compounds in subarachnoid hemorrhage patients with cerebral vasospasm. FASEB JOURNAL. vol. 15, A112-A112.
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